Clinical trials: SARS-CoV-2 Infection Covid19
Acute Respiratory Infection
Clinical Trial of Natural Therapeutics for COVID-19 and Other Acute Respiratory Viral Infections
The trial "Safety, Pharmacokinetics and Preliminary Efficacy of herbal products for the treatment of acute respiratory viral infections including SARS-CoV2 in Uganda; Phase 2A Open Label Clinical Trial" is currently being…
- Trial name
- CONAT (NCT05897203)
- Testing
- TAZCOV, Vidicine
- Where
- Uganda
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- Makerere University
Thalassemia Major, Covid19
Frequency of COVID-19 Antibodies in Patients With Hereditary Hematological Diseases
In Italy there are about 5000 patients with dependent transfusion thalassemia (source Italian Thalassemia and Hemoglobinopathies - SITE) and a smaller number, currently not definable, of patients with sickle cell anemia in…
- Trial name
- ThalaCoV (NCT04526405)
- Testing
- SARS-CoV-2 S1/S2 IgG
- Where
- Italy
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Milano Bicocca
Post COVID Condition
Sonlicromanol in Post-COVID
The aim of this randomized, double-blind, placebo-controlled, phase II trial, is to study the effect of sonlicromanol on fatigue in patients with post-COVID who experience post-exertional malaise (PEM).
- Trial name
- SON4PEM (NCT07298005)
- Testing
- Sonlicromanol
- Where
- Netherlands
- Volunteers
- 80 people
- Sponsor
- Michele van Vugt
COVID-19
Pulmonary Rehabilitation Implemented With VR for Post-COVID-19 Patients
Although the COVID-19 pandemic was announced almost 2 years ago, societies are still facing the effects not only of individuals but also of entire populations.
- Trial name
- NCT05242094
- Testing
- Pulmonary Rehabilitation Program
- Where
- Poland
- Volunteers
- 2,000 people
- Sponsor
- The Opole University of Technology
COVID-19, SARS-CoV 2
EXercise TRAining and Sedentary Lifestyle on Clinical Outcomes in Patients With COVID-19
The present study aims to assess the impact of exercise training, physical activity, and sedentary lifestyle on clinical outcomes in surviving patients infected with the severe acute respiratory syndrome coronavirus 2…
- Conditions
- COVID-19, SARS-CoV 2, Corona Virus Infection, Sedentary Behavior
- Trial name
- WHO (NCT04396353)
- Testing
- Electronic questionnaire
- Where
- Brazil
- Volunteers
- 1,574 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
COVID, Statin
Statin Therapy and COVID-19 Infection
Considering that simvastatin, and probably statins in general, interfere with SARS-cov-2 cellular uptake and some inflammatory pathways activated by the virus, those patients on statin therapy should be less vulnerable to…
- Conditions
- COVID, Statin, Cardiovascular Diseases
- Trial name
- STACOV (NCT04407273)
- Testing
- observational
- Where
- Spain
- Volunteers
- 2,159 people
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili
COVID-19
Glassy Trial for Effects of Wearing Glasses
Randomized trial testing 6 forms of a communication summarizing the results of a recent study (about the effects of wearing glasses on reducing covid infection risk).
- Trial name
- NCT05642754
- Testing
- Overall uncertainty language
- Where
- Norway
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- Trustees of Dartmouth College
COVID-19
Study on Determine the Utilisation and Clinical Outcomes of Evusheld in COVID-19 PrEP in China
Evusheld(AZD7442) is a combination of 2 human long-acting antibodies, which was selected for maximal potency and demonstrated synergistic neutralization of SARS-CoV-2 in vitro.
- Trial name
- CLEAR (NCT05917951)
- Where
- China
- Volunteers
- 248 people
- Sponsor
- AstraZeneca
Covid19
Clinical Efficiency of Surgical Masks and Filtering Face-piece 2 Masks
Recent results demonstrated an increased risk of COVID-19 infection among healthcare workers (HCW), particularly when access to personal protective equipment (PPE) was inadequate. (ref).
- Trial name
- NCT04823351
- Testing
- Surgical Mask
- Where
- Switzerland
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Nurse, Student
Psychological Impact of the Covid-19 Pandemic on Student Nurses
The World Health Organization (WHO) declared in early 2020 the emergence of a new highly contagious SARS-CoV-2 coronavirus responsible for a global public health emergency.
- Conditions
- Nurse, Student, Post Traumatic Stress Disorder, COVID-19
- Trial name
- StudentCov (NCT04402229)
- Where
- 2 sites in France
- Volunteers
- 2,000 people
- Sponsor
- Versailles Hospital
COVID-19
High Dose Inhaled Nitric Oxide for COVID-19 (ICU Patients)
Novel therapies are desperately needed for treatment of COVID-19 patients. At present, there are no proven interventions to prevent progression of the disease or to rapidly treat patients with COVID-19 related respiratory…
- Trial name
- NCT04383002
- Testing
- Nitric Oxide
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- University Health Network, Toronto
Emergency Medicine
Assessing Mixed Reality for Emergency Medical Care Delivery in a Simulated Environment
This study assessed the feasibility and effectiveness of using Mixed Reality (MR) through the use of HoloLens2TM technology to enhance emergency clinical care delivery in a simulated environment.
- Trial name
- NCT05870137
- Testing
- HoloLens2TM, Standard care
- Where
- United Kingdom
- Volunteers
- 22 people
- Sponsor
- Imperial College London
COVID-19 Infection, Sars-cov-2
Use of Dexmedetomidine in Light to Moderate Sedation in the Patient in the Palliative Situation of a Sars-cov-2 / COVID-19 Infection
The current sars-cov-2 epidemic is responsible for severe respiratory infections leading to end-of-life situations. Dexmedetomidine may be indicated in mild to moderate sedation in palliative patients, due to its pharmacological…
- Conditions
- COVID-19 Infection, Sars-cov-2, Respiratory Failure, Palliative Situation
- Trial name
- PRODEX (NCT04350086)
- Testing
- Treatment with Dexmedetomidine
- Where
- France
- Sponsor
- University Hospital, Limoges
Acute Respiratory Failure
A Check-list Including Lung Ultrasound for ED Patients With ARF
The aim of the study is to evaluate if a check-list including lung ultrasonography can help to identify the etiology of the acute respiratory failure of patients managed at the emergency room.
- Trial name
- CHECKIRA-COVID (NCT04791241)
- Testing
- check-list including lung ultrasound
- Where
- 3 sites in France
- Volunteers
- 105 people
- Sponsor
- Centre Hospitalier Metropole Savoie
COVID-19, Post-COVID-19 Syndrome
Cohort Follow-up of Epidemic and Neuroimaging for Patients During the 1st Wave of the COVID-19 in China
Our main objective is to analyze the development of physical impact, mental health and blood profile over follow-up time during the 1st wave of the COVID-19.
- Conditions
- COVID-19, Post-COVID-19 Syndrome, Acute COVID-19, Post-Acute COVID-19
- Trial name
- NCT05745805
- Testing
- Simultaneous cortico-spinal magnetic resonance imaging, Serum
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
SARS-CoV-2, Covid19
Clinical Evaluation of a Point-of-Care (POC), COVID-19 Rapid Antigen Test (CoviDx™)
Prospective study that will evaluate the clinical agreement of the CoviDx™ Rapid Antigen test compared to SARS-CoV-2 RT-PCR.
- Trial name
- CoviDx (NCT04750629)
- Testing
- POC CoviDx™ Rapid Antigen Test
- Where
- 2 sites in United States
- Volunteers
- 140 people
- Sponsor
- Lumos Diagnostics
Coronavirus Infections
In-depth Immunological Investigation of COVID-19.
The COntAGIouS trial (COvid-19 Advanced Genetic and Immunologic Sampling; an in-depth characterization of the dynamic host immune response to coronavirus SARS-CoV-2) proposes a transdisciplinary approach to identify host factors…
- Trial name
- COntAGIouS (NCT04327570)
- Testing
- Patient sampling
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Covid19, Kidney Transplant Infection
Optimized Management of Covid-19 Positive Kidney Transplant Recipients: Single Center Experience From the Middle East
Methods: Out of 2000 kidney transplant recipients in our center in Kuwait, collecting data was started for all COVID-19-positive kidney transplant recipients till August 2020.
- Conditions
- Covid19, Kidney Transplant Infection, Risk Factor, Cardiovascular, Immunosuppression
- Trial name
- OMC-KTR (NCT04542954)
- Testing
- Optimized Management of Covid-19 Positive Kidney Transplant Recipients: Single Center Experience from the Middle East
- Where
- Kuwait
- Volunteers
- 104 people
- Sponsor
- Hamid Al-Essa Organ Transplant Center
Supplemental Nutrition Assistance Program Education, Post COVID Syndrome
Effect of a Non-pharmacological Intervention on Endothelial Function, Body Composition, and Physical Functionality in Recovered COVID-19 Patients.
This study aims to evaluate the impact of a non-pharmacological treatment (nutritional therapy and pulmonary rehabilitation) on endothelial function, body composition, and physical functionality in recovered COVID-19 patients.
- Conditions
- Supplemental Nutrition Assistance Program Education, Post COVID Syndrome, Endothelial Function
- Trial name
- NCT07544186
- Testing
- L-citrulline supplementation
- Where
- Mexico
- Volunteers
- 43 people
- Sponsor
- Instituto Nacional de Enfermedades Respiratorias
COVID-19, Inflammation
SARS CoV-2 Infection and Inflammatory Biomarkers
Early research suggests that inflammation plays a key role in the development of SARS CoV-2 infection. The immune response to respiratory infection is characterized by an influx of neutrophils to the lungs.
- Trial name
- NCT05145751
- Testing
- Simple inflammatory biomarkers measurement
- Where
- Greece
- Volunteers
- 115 people
- Sponsor
- University of Thessaly
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