Clinical trials: SARS-CoV-2 Infection Covid19
COVID-19, SAR-CoV-2
Long-term Effects of COVID-19
The purpose of this study is to measure, monitor, and analyze long term effects of SARS-CoV-2. The main purpose is to assess the post-hospitalization outcomes of patients who were diagnosed with SAR-CoV-2 by comparing to patients…
- Trial name
- NCT05220514
- Testing
- (R)-1-(2-chlorophenyl)- N-[11C] ([11C] PK11195), 2-(4-[11C]methylamino phenyl)-6-hydroxybenzothiazole (11C]6-OH-BTA-1 or [11C]PIB)
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- Mayo Clinic
Hospitalized Patients With Covid-19 Pneumonia
Use of Ascorbic Acid in Patients With COVID 19
Different studies showed that ascorbic acid (vitaminC) positively affects the development and maturation of T-lymphocytes, in particular NK (natural Killer) cells involved in the immune response to viral agents.
- Trial name
- NCT04323514
- Testing
- Vitamin C
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- University of Palermo
Nociceptive Pain
Nociception and BIS Level Monitoring in COVID-19 Patients in the Intensive Care Unit
Pain (nociception), stress and discomfort are difficult to detect in sedated and intubated patients during mechanical ventilation.
- Trial name
- NEMO (NCT05579106)
- Testing
- Nociception Level Monitor (NOL) by Medasense Biometrics Ltd., Israel, Bispectral index (BIS), Questionnaire perception of the nurse on pain patient
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Leiden University Medical Center
SARS-CoV-2 Infection
A COVID-19 Study to Evaluate Safety and PK of COVID-HIG Administered Through IM, SC, or IV Routes to SARS-CoV-2 Uninfected Adults
The primary objectives of this open-label trial were to evaluate the safety and pharmacokinetics (PK) of Anti-SARS-CoV-2 Immunoglobulin (Human) Investigational Product (COVID-HIG) administered intramuscularly (IM), subcutaneously…
- Trial name
- NCT05142306
- Testing
- COVID-HIG
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Emergent BioSolutions
COVID-19
Improvement of the Nutritional Status Regarding Nicotinamide (Vitamin B3) and the Disease Course of COVID-19
Based on the literature, it seems likely that a nutritional intervention with nicotinamide (a form of vitamin B3) can support the therapy of SARS-CoV-2 infection (COVID-19).
- Trial name
- COVit-2 (NCT04751604)
- Testing
- Nicotinamide
- Where
- Germany
- Volunteers
- 900 people
- Sponsor
- University Hospital Schleswig-Holstein
Anal Fissure, Corona Virus Infection
Anal Fissure Among Survivors of COVID-19 Virus Infection.
Background Anal fissure is one of the most common anorectal problems. After an outbreak of coronavirus disease (COVID-19) has rapidly spread from China to almost all over the world, it nearly affected all countries.
- Trial name
- NCT05736926
- Where
- Egypt
- Volunteers
- 176 people
- Sponsor
- Mansoura University
Coronavirus, Depression
Social Media and COVID-19
In this protocol, we seek to examine the role of popular messaging platform WhatsApp in information spread during a crisis. As there have been few global crises in the last decade (coinciding with the rise of social media), the…
- Conditions
- Coronavirus, Depression, Anxiety, Stress
- Trial name
- NCT04367363
- Testing
- Social media & news consumption
- Where
- Singapore
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Jean Liu
Covid-19
Exploratory Study to Evaluate the Efficacy of RUTI® Against SARS-COV-2 Infection (COVID-19) in Healthcare Workers
The aim of this study is to explore potential for reduction of incidence and/or morbidity of SARS-CoV-2 infection in healthcare personnel. The study will include a comparison between placebo and RUTI® vaccine in a 2:1 design.
- Trial name
- NCT04903184
- Testing
- RUTI® vaccine
- Where
- 6 sites in Argentina
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- RUTI Immunotherapeutics S.L.
COVID 19 Disease
Tafenoquine in Patients With Mild to Moderate COVID-19
A clinical study to assess the efficacy and safety of oral tafenoquine compared to placebo in patients with mild to moderate COVID 19 disease.
- Trial name
- NCT04533347
- Testing
- Tafenoquine Oral Tablet
- Where
- 10 sites in United States
- Volunteers
- 86 people
- Sponsor
- 60 Degrees Pharmaceuticals LLC
Covid19, COVID-19 Respiratory Infection
Standardized Olive Leaf Capsules; as a Co-therapy in the Treatment of COVID-19 Patients
Starting from December 2019, novel coronavirus disease 2019 (COVID-19) pandemic has caused a tremendous economic loss and unprecedented health crisis across the globe.
- Conditions
- Covid19, COVID-19 Respiratory Infection, Symptoms and Signs, COVID-19 Acute Bronchitis
- Trial name
- NCT04873349
- Testing
- Nusapure standardized olive leaves capsule, 750 mg (50% oleuropein)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Shimaa M. Abdelgawad
COVID-19, Cardiovascular Diseases
The McGill RAAS-COVID-19 Trial
Coronavirus disease (COVID-19) related pneumonia significantly impact patients with underlying cardiovascular (CV) conditions. Animal studies suggest that drugs commonly used to treated CV diseases may increase the ability of…
- Trial name
- RAAS-COVID (NCT04508985)
- Testing
- Temporarily holding the RAAS inhibitor [intervention], RAAS inhibitor [continued standard of care]
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
COVID-19
A Study to Determine the Tolerability of Intranasal LMN-301
LMN-301 is to prevent infection by severe acute respiratory syndrome-corona virus (SARS-CoV-2) (the virus causing coronavirus disease of 2019 (COVID-19) in uninfected individuals.
- Trial name
- NCT06030414
- Testing
- LMN-301
- Where
- Australia
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Lumen Bioscience, Inc.
Covid19, Corona Virus Infection
Expanded Access to Zofin for Patients With COVID-19
This expanded access protocol will provide access to the investigational product Zofin for patients in outpatient facilities infected with SARS-CoV-2 who have mild to moderate COVID-19, or who are judged by a healthcare provider…
- Conditions
- Covid19, Corona Virus Infection, SARS (Severe Acute Respiratory Syndrome), Acute Respiratory Distress Syndrome
- Trial name
- NCT04657406
- Testing
- Zofin
- Sponsor
- ZEO ScientifiX, Inc.
Chronic Kidney Disease Stage 5 on Dialysis, Chronic Kidney Disease Stage 5 With Transplant
Vaccination Against COVID-19 in Chronic Kidney Disease
This is a prospective, multi-center, observational study that will enroll patients receiving dialysis (hemodialysis or peritoneal dialysis) or patients with kidney transplantation who will be vaccinated against COVID-19.
- Conditions
- Chronic Kidney Disease Stage 5 on Dialysis, Chronic Kidney Disease Stage 5 With Transplant, Vaccine Response Impaired
- Trial name
- NCT04743947
- Testing
- No intervention; observational study
- Where
- 5 sites in Germany
- Volunteers
- 400 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
COVID, SARS-CoV 2
COVID19 Clinical Predictors and Outcome
In December 2019, a novel coronavirus (SARS-CoV-2) emerged in Wuhan, Hubei, China, and now spreads across international borders.
- Trial name
- NCT04416347
- Testing
- SARS-CoV2 Infection
- Where
- United Kingdom
- Volunteers
- 800 people
- Sponsor
- St George's University Hospitals NHS Foundation Trust
COVID-19
Recombinant Hyperimmune Polyclonal Antibody (GIGA-2050) in COVID-19 Patients
The purpose of this study is to evaluate the safety and tolerability of single ascending IV dose administrations of GIGA-2050 in patients hospitalized with COVID-19.
- Trial name
- NCT04883138
- Testing
- GIGA-2050
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- GigaGen, Inc.
Tracheostomy
Percutaneous Tracheostomy With COVID-19
Coronavirus disease 2019 (COVID-19) has brought about a requirement of intensive care and mechanical ventilation for a significant portion of patients.
- Trial name
- NCT04447638
- Testing
- Tracheostomy with aerosol box in COVID-19 positive patients
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Çanakkale Onsekiz Mart University
Coronavirus Infection
Clinical Evaluation of Cordio Application in Adult COVID-19 Virus Positive Patients
Study on adult patients positive to COVID-19 virus. After signing informed consent and undergoing screening assessments, eligible patients will record few times a day several pre-defined sentences to the Cordio App installed in a…
- Trial name
- NCT04325048
- Testing
- Cordio App
- Where
- Israel
- Volunteers
- 42 people
- Sponsor
- Cordio Medical
Vaccination
Effect of Electronic and Mail Outreach From Primary Care Physicians for COVID-19 Vaccination Among Elderly Patients
This randomized controlled trial tested the effect of culturally tailored and standard electronic secure messages and mailings from patients' primary care physicians to encourage COVID-19 vaccination among adults aged 65 and…
- Trial name
- NCT05096026
- Testing
- Standard PCP Outreach, Culturally Tailored PCP Outreach
- Where
- United States
- Volunteers
- 8,287 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Bronchoalveolar Lavage
Bronchoalveolar Lavage in Recovered From COVID-19 Pneumonia
Coronaviruses such as SARS-CoV2, MERS-CoV, and SARS-CoV can cause significant morbidity and mortality in infected persons. Lung is the most common site of infection for these viruses, which may manifest as acute respiratory…
- Trial name
- NCT06022198
- Testing
- Bronchoalveolar Lavage
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mohamed Abd Elmoniem Mohamed
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