Clinical trials: SARS-CoV-2 Infection Covid19
Neck Pain
Distance Learning and Neck Problems During Pandemic Period
For people who use computers a lot, Work-related musculoskeletal disorders of the neck are a common problem . It is generally agreed that the etiology of work-related neck disorders is multidimensional which is associated with…
- Trial name
- NCT04925999
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Misr University for Science and Technology
Post-COVID-19 Syndrome, Post-COVID Syndrome
Immunoadsorption Study Mainz in Adults With Post-COVID Syndrome
The aim of this study is to evaluate the efficiency and safety of immunoadsorption for the treatment of post-COVID syndrome (PCS).
- Conditions
- Post-COVID-19 Syndrome, Post-COVID Syndrome, Post COVID-19 Condition
- Trial name
- IAMPOCO (NCT05841498)
- Testing
- Immunoadsorption
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University Medical Center Mainz
Covid19, Endoplasmic Reticulum Stress
High GRP78 Levels in Covid-19 Infection: A Case-Control Study
Covid-19 infection was declared a global pandemic by WHO on March 11, 2020. GRP78 protein is known to be involved in the intrusion of numerous viruses.
- Trial name
- NCT04628637
- Testing
- Serum protein level analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Kafkas University
Vitamin D Deficiency, Covid19
The Relationship Between Vitamin D Levels, Inflammatory Parameters and Disease Severity of COVID-19 Infection
Vitamin D deficiency increases the susceptibility to respiratory virus infections and the severity of infections. Inflammation plays a key role in pathogenesis in COVID19 while identifying clinical course and prognosis…
- Trial name
- NCT04945577
- Testing
- Inflammatory Parameters, 25 OH Vitamin D Level
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Covid19
Povidone-Iodine Rinses in the Management of COVID-19
The aim of this study is to determine if Povidone iodine (PVP-I) rinses and throat gargles or a PVP-I gel forming nasal spray compared to a placebo (a treatment that has no physical effect to a person) is an effective treatment…
- Trial name
- NCT04449965
- Testing
- Povidone-iodine
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- St. Paul's Hospital, Canada
SARS-CoV 2
Immune Responses to COVID-19; Isolation of Neutralizing Antibodies for Therapeutics and Vaccine.
According to different projections, the COVID-19 outbreak currently happening in France and worldwide could result in millions of deaths in the absence of efficient therapies.
- Trial name
- AcNT-COVID19 (NCT04596098)
- Testing
- Blood sampling
- Where
- France
- Volunteers
- 55 people
- Sponsor
- University Hospital, Grenoble
Covid-19
Study to Evaluate STI-1499 (COVI-GUARD) in Patients With Moderate COVID-19
Randomized, placebo-controlled study to evaluate the safety, pharmacokinetics and efficacy of a single dose of STI-1499 (COVI-GUARD™) in hospitalized patients with moderate COVID-19
- Trial name
- NCT04454398
- Testing
- COVI-GUARD, Standard of Care
- Sponsor
- Sorrento Therapeutics, Inc.
Covid19
Study to Evaluate the Clinical Outcomes in Adults With Covid-19 Who Have Been Treated With Remdesivir.
This is a multi-centre, multi-country retrospective cohort study. At least 450COVID-19 cases from up to 20 participating study sites who meet all eligibility criteria will be included in the analysis.
- Trial name
- 909REM (NCT04847622)
- Testing
- Remdesivir
- Where
- 12 sites in France, Israel and 3 more
- Volunteers
- 451 people
- Sponsor
- NEAT ID Foundation
COVID-19
Short-time Intervention in Post-Covid Syndrome Syndrome (SIPCOV): A Pragmatic Randomised Controlled Trial
The present study is a 2-arm pragmatic randomised controlled trial (RCT) in which 310 patients who suffer from post-Covid syndrome are randomised to either a short-time outpatient-based rehabilitation program (the intervention)…
- Trial name
- SIPCOV (NCT05196451)
- Testing
- Rehabilitation based on CBT principles
- Where
- Norway
- Volunteers
- 314 people
- Sponsor
- University Hospital, Akershus
Covid19
Symptom-Based Markers for COVID-19 Transmission
In this study, COVID-19 positive patients will be added to a bidirectional texting program to receive daily surveys about their symptoms with the infection.
- Trial name
- NCT04665245
- Where
- United States
- Volunteers
- 214 people
- Sponsor
- University of Iowa
Breast Cancer, Iron Chelation
Ketotifen: as a Cardioprotective Agent in Breast Cancer Patients Receiving Anthracycline-containing Chemotherapy
The objective of our study was to evaluate the expected cardioprotective effects of ketotifen due to its activity as an iron-chelating agent previously uncovered by us in the in vitro chemical test which included in the study…
- Trial name
- NCT04435028
- Testing
- Ketotifen 1 MG
- Where
- Egypt
- Volunteers
- 111 people
- Sponsor
- Horus University
COVID-19
#StayHome: Early Hydroxychloroquine to Reduce Secondary Hospitalisation and Household Transmission in COVID-19
BACKGROUND Despite drastic quarantine measures, COVID-19 continues to propagate and threatens global healthcare systems by saturating their capacity with high transmissibility and the particularly protracted length of stay needed…
- Trial name
- #StayHome (NCT04385264)
- Testing
- Hydroxychloroquine, Mannitol
- Where
- Switzerland
- Volunteers
- healthy volunteers welcome
- Sponsor
- Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland
Ventilator Associated Pneumonia
Microbial Etiology of Ventilator-associated Pneumonia in COVID-19 Infected Patients
National multicentric observational retrospective case-control study comparing the relative frequency of the various microorganisms responsible for VAP in patients infected or not by SARS-CoV-2 and their resistance to antibiotics.
- Trial name
- NCT04344509
- Testing
- Bacterial species isolated
- Volunteers
- 10,000 people
- Sponsor
- Poitiers University Hospital
Post-COVID-19 Syndrome
Physiotherapy in Post COVID-19 Syndrome Patients
Patients who have undergone COVID-19 infection often have long-term sequelae. One of the most prevalent sequelae is pain. The main objective of this research is to investigate the efficacy of a cognitive behavioral…
- Trial name
- NCT05477199
- Testing
- Cognitive behavioral principles-based treatment program, Control intervention
- Where
- Spain
- Volunteers
- 54 people
- Sponsor
- Universidad de Granada
Mental Health, PTSD
Further Development and Initial Testing of RESTORE in Frontline Workers
There is considerable need for psychological intervention targeting stressor-related mental health symptoms related to COVID-19.
- Conditions
- Mental Health, PTSD, Anxiety, Depressive Symptoms
- Trial name
- RESTORE (NCT04873622)
- Testing
- RESTORE: Recovering from Extreme Stressors Through Online Resources and E-health
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
COVID-19 Infection
Long Covid (Individuals with Ongoing COVID-19 Symptoms) Ongoing Effects
Persistent Covid-19 symptoms, known as long Covid, can impact healthcare provision. This study aimed to assess how symptoms persisting six months after Covid-19 affect quality of life and functional capacity.
- Trial name
- COVID-19 (NCT06528145)
- Testing
- Evalation
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ziya Yildiz
Covid19
Elderly Patients and COVID-19 Infection: a Cohort of Fifty Patients Over Ninety Years of Age
SARS-CoV2 or CoVid19 disease is a newly described pathology linked to a subtype of the coronavirus family identified in China in December 2019.
- Trial name
- NCT04499300
- Testing
- Data collection from medical files
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Murielle Surquin
Coronavirus Disease (COVID-19)
Feasibility of Rapid COVID-19 Testing in Disadvantaged Populations
The purpose of this study is to assess the feasibility of establishing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing at a federally-qualified health center (FQHC) during a global health crisis to mitigate…
- Trial name
- NCT04558307
- Testing
- Pilot a rapid SARS-CoV-2 testing strategy, Community-driven messages to promote COVID-19 testing
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
COVID-19 Disease
Back to the Traditional: Anti-COX Drugs Can Improve the Outcome of COVID-19 Patients Admitted to ICU
Retrospective multicenter study to evaluate the data of COVID-19 patients who were admitted to university hospitals in relation to their recent administration or maintenance on non-steroidal anti-inflammatory drugs (NSAID) prior…
- Trial name
- NCT04757792
- Testing
- File inquiry
- Where
- Egypt
- Volunteers
- 475 people
- Sponsor
- Benha University
Pneumonia, COVID-19
A Study to Evaluate Efficacy and Safety of PTC299 (Emvododstat) in Hospitalized Participants With Coronavirus (COVID-19)
This is a randomized, double-blind, placebo-controlled, multicenter, 28-day study of adult participants hospitalized with COVID-19, with a safety follow-up telephone call at Day 60.
- Conditions
- Pneumonia, COVID-19, Coronavirus
- Trial name
- FITE19 (NCT04439071)
- Testing
- PTC299, SOC
- Where
- 41 sites in United States, Australia and 9 more
- Volunteers
- 189 people
- Sponsor
- PTC Therapeutics
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