Clinical trials: SCI - Spinal Cord Injury
Spinal Cord Injury, Paraplegia
Exoskeletal-assisted Walking to Improve Mobility, Bowel Function and Cardio-Metabolic Profiles in Persons With SCI
The primary objective of this study is to achieve successful walking skills using exoskeletal walking devices over the course of 36 sessions in 3 months at specific velocities and distances in people with chronic SCI who are…
- Conditions
- Spinal Cord Injury, Paraplegia, Tetraplegia
- Trial name
- EAWSCI (NCT02314221)
- Testing
- Exoskeletal-assisted walking (ReWalk, Ekso)
- Where
- 3 sites in United States
- Volunteers
- 73 people
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Osteoporosis, Bone Loss
Effect of Parathyroid Hormone (PTH) and Weight-Bearing on Bone in Spinal Cord Injury (SCI)
Individuals with spinal cord injury sustain significant loss of bone mass in their lower extremities (20-40% or more). This study evaluates the ability of PTH and weight-bearing, two interventions that build bone, to increase…
- Conditions
- Osteoporosis, Bone Loss, Spinal Cord Injury
- Trial name
- NCT00826228
- Testing
- teriparatide, weight-bearing
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Thomas J. Schnitzer
Spinal Cord Injury, Neurogenic Bladder
Multifaceted Treatment of Catheter-related Urinary Tract Infection
The specific objective of this clinical trial is to demonstrate that a multifaceted approach for treatment for catheter-related urinary tract infection (UTI) in patients with spinal cord injury is effective and feasible.
- Conditions
- Spinal Cord Injury, Neurogenic Bladder, Urinary Tract Infection
- Trial name
- NCT00732238
- Testing
- Shortened course of antibiotic therapy, Standard Therapy
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- US Department of Veterans Affairs
SCI - Spinal Cord Injury, Incomplete Spinal Cord Injury
Stimulation to Enhance Walking Post-SCI
This pilot study will investigate the effects of transcutaneous direct current stimulation (tsDCS) on walking function in individuals with incomplete spinal cord injury.
- Trial name
- NCT03702842
- Testing
- Soterix Medical tsDCS stimulator, Locomotor training
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Florida
Orthostatic Hypotension, Spinal Cord Injuries
A Study of Blood Pressure and Blood Supply to the Brain in Persons With a Spinal Cord Injury.
The purpose of this study is to determine how blood pressure and blood flow are controlled during head-up tilt in a semi-upright position.
- Trial name
- NCT00248807
- Testing
- 1.25 mg enalaprilat IV, Head up tilt (HUT)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Spinal Cord Injuries
Feasibility of Exercise and Spinal Cord Injury
The purpose of the study is to examine the impact of a community-based exercise intervention (CBEI) for persons with spinal cord injury (PwSCI) on physiological and psychological well-being and identify barriers and facilitators…
- Trial name
- NCT03941600
- Testing
- Community-based Exercise Intervention group (CBE), Exercise Education Control group (EEG)
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Washington University School of Medicine
Immobilization
Time Performance of Scoop Stretcher Versus Vacuum Mattress for Prehospital Spinal Stabilization
A simulation-based randomized controlled trial was designed with the objective to assess the time needed to achieve spinal stabilization using a scoop stretcher compared to a vacuum mattress.
- Trial name
- NCT04904770
- Testing
- Scoop stretcher, Vacuum mattress
- Where
- Switzerland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Stuby Loric
Spinal Cord Injury
Acute Effect of Ventilatory Support During Exercise in Spinal Cord Injury
The investigators have an existing exercise program (N>70) with a unique population of individuals with spinal cord injury (SCI) who have been enrolled in Functional Electrical Stimulation - Rowing Training (FES-RT) for at least…
- Trial name
- NIV-Ex-CS (NCT03267212)
- Testing
- Non-invasive ventilation(NIV), Functional Electrical Stimulation Row Training (FESRT)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Spaulding Rehabilitation Hospital
Spinal Cord Injuries, Paraplegia
Multimodal Exercises to Improve Leg Function After Spinal Cord Injury
Many people with spinal cord injury (SCI) retain at least some movement below their injury, but their muscles often have a 'mind of their own'.
- Conditions
- Spinal Cord Injuries, Paraplegia, Paraparesis
- Trial name
- NCT01740128
- Testing
- Robotic body weight supported treadmill training, Harness-supported multimodal balance training
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- VA Office of Research and Development
Spinal Cord Injury, Spinal Cord Injuries
Testosterone Plus Finasteride Treatment After Spinal Cord Injury
The purpose of this study is to determine whether testosterone plus finasteride treatment will improve musculoskeletal health, neuromuscular function, body composition, and metabolic health in hypogonadal men who have experienced…
- Conditions
- Spinal Cord Injury, Spinal Cord Injuries, Trauma, Nervous System, Wounds and Injuries
- Trial name
- NCT02248701
- Testing
- Testosterone Enanthate, Finasteride
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- VA Office of Research and Development
Spinal Cord Injury
Respiratory Resistance Training on Sleep Quality in Persons With Spinal Cord Injury
The purpose of this study is to determine if the use of a respiratory resistance trainer will increase respiratory muscle strength, improve sleep quality and improve quality of life in individuals with spinal cord injury.
- Trial name
- NCT00629850
- Testing
- Powerlung Performer
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Texas State University, San Marcos
Spinal Cord Injury/Disorder
Evaluation of Vision-Guided Shared Control for Assistive Robotics Manipulators
The purpose of this study is to evaluate a new control (i.e., the vision-guided shared (VGS) control) for a wheelchair-mounted assistive robotic manipulator among powered wheelchair users.
- Trial name
- ARM Control (NCT04323449)
- Testing
- Compare two control methods for a wheelchair-mounted robotic manipulator
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- VA Office of Research and Development
Spinal Cord Injuries
Repeated Subarachnoid Administrations of hUC-MSCs in Treating SCI
The purpose of this study is to evaluate the safety and efficacy of repeated intrathecal administrations of allogeneic human umbilical cord mesenchymal stem cells for the treatment of spinal cord injury.
- Trial name
- NCT02481440
- Testing
- human umbilical cord mesenchymal stem cells (hUC-MSCs)
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Limin Rong