Clinical trials: SCS
Chronic Pain
Use of Dermabond in Mitigation of Spinal Cord Stimulation (SCS) Trial Lead Migration
During the typical SCS trial the leads remain outside of the skin and can be prone to migration. The leads are typically secured in place with suture, tape, or a combination of both.
- Trial name
- NCT05914311
- Testing
- Suture, Suture and Dermabond
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Wake Forest University Health Sciences
Back Pain With Radiation
Evaluation of the Percutaneous SCS Trial Using the DSSEP Collision Testing
This study is to objectively evaluate the success of a spinal cord stimulator (SCS) trial using testing (DSSEP) to determine if the paresthesia (tingling sensation) or pain reduction achieved correlates with the degree of…
- Trial name
- NCT02614079
- Testing
- DSSEP
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Toledo Health Science Campus
Chronic Pain
Study of Gemini Rechargeable Spinal Cord Stimulation (SCS) System
The aim of this pre-market, prospective, single-arm, non-randomized, open-label, multi-center clinical study is to collect confirmatory data to show that the Gemini SCS neurostimulation system functions as intended in a clinical…
- Trial name
- NCT05590000
- Testing
- Gemini SCS neuromodulation system
- Where
- 6 sites in Australia
- Volunteers
- 25 people
- Sponsor
- Abbott Medical Devices
Limb Pain, Trunk Pain
SCS Research Study
To characterize the effects of stimulation parameters on pain relief and other cohort specific outcomes.
- Trial name
- NCT03763708
- Testing
- Spinal Cord Stimulation
- Where
- 9 sites in United States
- Volunteers
- 100 people
- Sponsor
- MedtronicNeuro
Spinal Cord Injuries, Paraplegia, Spinal
Transspinal Stimulation Plus Locomotor Training for SCI
Locomotor training is often used with the aim to improve corticospinal function and walking ability in individuals with Spinal Cord Injury.
- Conditions
- Spinal Cord Injuries, Paraplegia, Spinal, Tetraplegia/Tetraparesis, Paraplegia, Spastic
- Trial name
- NCT04807764
- Testing
- Standing transspinal stimulation followed by robotic gait training, Lying transspinal stimulation followed by robotic gait training
- Where
- 2 sites in United States
- Volunteers
- 14 people
- Sponsor
- City University of New York
Pain, Intractable, Pain, Chronic
Comparison of DTM™ SCS Therapy Combined With Conventional Medical Management (CMM) to CMM Alone in the Treatment of Intractable Back Pain Subjects Without Previous History of Lumbar Spine Surgery
The purpose of this investigational study is to document the safety, clinical effectiveness and health economic analytics of DTM™ SCS programming delivered through the Intellis™ neurostimulator in subjects with chronic…
- Trial name
- NCT06442410
- Testing
- DTM™ spinal cord stimulation therapy delivered via Intellis™ neurostimulator system, Conventional Medical Management (CMM)
- Where
- 12 sites in Belgium, Germany and 2 more
- Volunteers
- 115 people
- Sponsor
- MedtronicNeuro
Chronic Pain, Low Back Pain
High Frequency Stimulation Trials in Patients With Precision Spinal Cord Stimulator System
Study designed to compare the conventional stimulation programming versus the high frequency stimulation programming of the spinal cord stimulator for subjects who already have a spinal cord stimulator.
- Conditions
- Chronic Pain, Low Back Pain, Radiculopathy, Complex Regional Pain Syndrome (CRPS)
- Trial name
- HFSCS (NCT02265848)
- Testing
- High frequency stimulation, Low frequency stimulation
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- The Center for Clinical Research, Winston-Salem, NC
Back Pain, Chronic Pain
Effectiveness of Precision Spinal Cord Stimulation With Artisan Paddle Electrode
The primary objective of this study is to evaluate the acute and chronic efficacy of spinal cord stimulation using the Precision implantable neurostimulation device with the Artisan paddle electrode in patients with Failed Back…
- Conditions
- Back Pain, Chronic Pain, Pain in Leg, Unspecified
- Trial name
- NCT00386724
- Testing
- Precision Spinal Cord Stimulation System, Artisan Surgical Lead
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- Boston Scientific Corporation
Low Back Pain
Effects of Programming Parameters on Back Pain Relief in Subthreshold Spinal Cord Stimulation
The purpose of this study is to investigate the effects of varying programming parameters in subthreshold spinal cord stimulation therapy for pain relief.
- Trial name
- NCT01550562
- Testing
- Boston Scientific Precision Plus spinal cord stimulation therapy
- Where
- Australia
- Volunteers
- 1 people
- Sponsor
- Boston Scientific Corporation
Chronic Pain, Pain, Chronic
APM in the Evoke SCS System to Program Patients With Chronic Pain of the Trunk and/or Limbs
Study to evaluate the use of the Assisted Programming Module (APM) in the Evoke Spinal Cord Stimulation (SCS) System to program patients with chronic pain of the trunk and/or limbs.
- Trial name
- APM (NCT06057480)
- Testing
- Evoke Spinal Cord Stimulation System
- Where
- 4 sites in United States
- Volunteers
- 30 people
- Sponsor
- Saluda Medical Pty Ltd
Chronic Pain
Focal Pain Outcomes Using Configurations Applied for Lateral Stimulation
To evaluate programming modalities at various targets for focal foot, knee pain, and groin pain relief.
- Trial name
- FOCAL (NCT04073446)
- Testing
- Spinal Cord Stimulation
- Where
- Belgium
- Volunteers
- 3 people
- Sponsor
- Boston Scientific Corporation
Chronic Pain
PROLONG Prospective, Multi-center, Open-label, Post-market Study
Spinal cord stimulation (SCS) has been shown to be effective for relieving intractable chronic pain. However, a portion of patients who initially succeed with SCS will eventually lose their therapeutic benefit.
- Trial name
- PROLONG (NCT03908476)
- Testing
- Burst-capable SCS system, DRG Stimulator
- Where
- 21 sites in United States
- Volunteers
- 118 people
- Sponsor
- Abbott Medical Devices
Chronic Pain
Clinical Outcomes Study Using a New Implantable Neurostimulation System for Chronic Intractable Pain
The primary objective of this study is to investigate patient satisfaction with treatment using a new implantable neurostimulation system for chronic pain of the trunk and/or limbs.
- Trial name
- NCT01665040
- Testing
- Neurostimulation device implantation
- Where
- 7 sites in Australia, Belgium and 1 more
- Volunteers
- 40 people
- Sponsor
- Boston Scientific Corporation
Chronic Pain
Comparing Long-term Effectiveness of High Frequency and Burst Spinal Cord Stimulation
Over 100 million Americans suffer from chronic pain resulting in annual cost of roughly $635 billion. Limited treatments are available for this widespread disease.
- Trial name
- NCT03681262
- Testing
- High frequency spinal cord stimulation, Burst spinal cord stimulation
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Stanford University
Pain, Low Back Pain
Changes in Cerebral Blood Flow in Patients Treated With Spinal Cord Stimulation for Low Back and Leg Pain
The primary objective of this study is to identify the brain regions in which activity is affected by SCS. Baseline cerebral blood flow scans with the device turned off will be generated compared to scans produced with the device…
- Conditions
- Pain, Low Back Pain, Leg Pain
- Trial name
- NCT00418301
- Testing
- Precision Spinal Cord Stimulation and PET Scan
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Boston Scientific Corporation
Chronic Low Back Pain, Chronic Leg Pain
Comparison of the Effects of Two Spinal Cord Stimulation (SCS) Therapies on Subject Reported Pain (BENEFIT-02)
A BIOTRONIK wearable stimulator will be utilized in order to investigate the effects of two study spinal cord stimulation (SCS) therapies on subject reported pain and paresthesia perception observed over 12 days of study…
- Trial name
- NCT03594266
- Testing
- Therapy A spinal cord stimulation parameter set using BIO-RNA system and associated components, Therapy B spinal cord stimulation parameter set using BIO-RNA system and associated components
- Where
- 18 sites in United States
- Volunteers
- 136 people
- Sponsor
- Biotronik, Inc.
Chronic Pain
Randomized Study of Failed SCS Trials Comparing Outcomes Using the Observational Mechanical Gateway (OMG) Connector
The purpose of this study is to evaluate patient preference of the Boston Scientific Corporation (BSC) commercially approved spinal cord stimulation (SCS) systems with the Observational Mechanical Gateway (OMG) in patients who…
- Trial name
- RESCUE (NCT01643213)
- Testing
- Non Boston Scientific SCS Trial Therapy, BSC approved SCS Trial Therapy w/ OMG
- Where
- 13 sites in United States
- Volunteers
- 27 people
- Sponsor
- Boston Scientific Corporation
Chronic Pain, Neuropathic Pain
Intraoperative Neuromonitoring Recording With a Novel SCS Paddle
The purpose of this study is to demonstrate safety and efficacy of a new spinal cord stimulation paddle electrode which is able to target the dorsal horns, dorsal nerve roots, and dorsal columns.
- Conditions
- Chronic Pain, Neuropathic Pain, Failed Back Surgery Syndrome, Complex Regional Pain Syndromes
- Trial name
- NCT05045625
- Testing
- HD Study Electrode
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Albany Medical College
Upper Limb, Pain
Observational, Post Market Study in Treating Chronic Upper Extremity Limb Pain
This is a post-market, open-label, prospective, multi-center, observational study evaluating upper limb pain relief with the DTM™ SCS programming approach.
- Trial name
- PROC2020PM (NCT04466111)
- Testing
- Intellis neurostimulator system
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- SGX Procura LLC
Chronic Pain
VELOCITY: A Study to Characterize Real-World Outcomes of Spinal Cord Stimulation
The primary objective of this study is to characterize the real-world outcomes of spinal cord stimulation (SCS) therapy as an aid in the management of chronic intractable pain of the trunk, including unilateral or bilateral pain…
- Trial name
- NCT02741297
- Testing
- Spinal Cord Stimulation (SCS) System
- Where
- 5 sites in Germany, Italy and 2 more
- Volunteers
- 73 people
- Sponsor
- Boston Scientific Corporation