Clinical trials: SPECT-CT, open to volunteers
Prostate Cancer
99mTc-P137 SPECT/CT in Prostate Cancer
Purpose: This study will take prostate specific membrane antigen (PSMA) as the targeting of radionuclide labeled molecular probe to explore the diagnostic efficacy of 99mTc-P137 radioactive probe in prostate cancer.
- Trial name
- NCT05672485
- Testing
- SPECT/CT imaging with 99mTc-P137 nuclide probe
- Where
- China
- Volunteers
- 40 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Renal Cell Carcinoma (Kidney Cancer)
Study of 111In-XYIMSR-01 SPECT/CT in Patients With Metastatic Clear Cell Renal Cell
This study is being done to determine if the investigational radiotracer called 111In-XYIMSR-01 is helpful in detecting clear cell renal cell carcinoma tissue in your body when used during a SPECT-CT Scan
- Trial name
- NCT07062549
- Testing
- 111In-XYIMSR-01
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Hyperparathyroidism
NUclear MEdicine DIagnostic and Artificial Intelligence
Artificial intelligence algorithms for parathyroid adenoma detection in parathyroid scans The aim of the study is to develop programs for the automatic subtraction of planar and tomographic parathyroid images and for the…
- Trial name
- NUMEDIA (NCT05963841)
- Testing
- treatment program
- Where
- France
- Volunteers
- 1 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
SPECT-CT
Single Photon Emission Computed Tomography/Computed Tomography (SPECT/CT) Prospective Double-Scanning Study
The goal of this study is to collect image data for the StarGuide GX Single Photon Emission Computed Tomography/Computed Tomography (SPECT/CT) System in a clinical setting.
- Trial name
- NCT07725237
- Testing
- StarGuide GX SPECT/CT Scan
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Breast Cancer
99mTc-MY6349 SPECT/CT Imaging in Trop2-positive Triple-negative Breast Cancer
Human trophoblast cell-surface glycoprotein antigen 2 (Trop2) is a membrane surface receptor that plays an important role in the occurrence and development of tumors.
- Trial name
- NCT06104085
- Testing
- 99mTc-MY6349 SPECT/CT scan
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking Union Medical College Hospital
Parathyroid Adenoma
99mTc Sestamibi SPECT/CT vs 18F Fluorocholine PET/CT
This study proposes the use of a well-established PET isotope, Fluorine-18 (18F), bound to Choline, for a prospective single-center, single-arm study for participants with suspected parathyroid adenoma and negative or equivocal…
- Trial name
- 18FCH (NCT05891769)
- Testing
- 18Fluorocholine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Andrei Iagaru
Rheumatoid Arthritis (RA)
Research on the Application of 99mTc-TCR-FAPI SPECT Imaging in Rheumatoid Arthritis
This study proposes to evaluate 99mTc-CTR-FAPI SPECT imaging as a cost-effective, low-radiation, and widely accessible alternative to 68Ga-FAPI PET/CT for assessing synovial lesions in RA patients, aiming to validate its…
- Trial name
- NCT07138729
- Testing
- 68Ga-FAPI PET/CT and 99mTc-CTR-FAPI SPECT
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Luo Yaping
Bone Lesion, SPECT-CT
A Study on the Diagnostic Value of 99mTc-FAPI Quantitative SPECT/CT Imaging in Adult Solitary Bone Lesions
Using the novel FAPI probe 99mTc-HYNIC-FAPI-04 and quantitative SPECT/CT imaging technology, this study investigates the diagnostic efficacy of 99mTc-HYNIC-FAPI-04 quantitative SPECT/CT in patients with common solitary bone…
- Trial name
- NCT07114211
- Testing
- 99mTc-HYNIC-FAPI-04 SPECT-CT
- Volunteers
- 50 people
- Sponsor
- Xijing Hospital
Prostate Cancer
99mTc-MIP-1404 SPECT/CT in Primary Staging of Prostate Cancer
Prostate cancer (PCa) is currently the most common cancer in men in Finland (www.cancerregistry.fi). Although prognosis is very good in majority of men, it is noteworthy that still up to 20% of PCa cases are metastatic at the…
- Trial name
- NCT06219746
- Testing
- PSMA-imaging
- Where
- Finland
- Volunteers
- 320 people
- Sponsor
- Turku University Hospital
Knowledge
Knowledge and Attitudes About Advanced Maxillofacial Imaging in Dental Professionals
Introduction: Advanced maxillofacial imaging techniques, such as CBCT, CT, MRI, and hybrid modalities (PET/CT and SPECT/CT), have transformed diagnosis and treatment planning in dentistry.
- Trial name
- KAAMI (NCT07651969)
- Testing
- Submit a questionnaire
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Amyloidosis Transthyretin
Quantitative Analysis of Myocardial Uptake of Bone Radiopharmaceuticals in Patients With Cardiac ATTR Amyloidosis
Introduction: Transthyretin cardiac amyloidosis (ATTR) is an important cause of heart failure. Cardiac planar radionuclide imaging using 99mTc-labeled bone seeking radiopharmaceuticals is used as a noninvasive diagnostic…
- Trial name
- REMOD-TTR (NCT04535349)
- Testing
- Whole-body & CZT bone tracer imaging (SPECT)
- Where
- 2 sites in France
- Volunteers
- 35 people
- Sponsor
- University Hospital, Caen
Oropharyngeal Squamous Cell Carcinoma, Oropharyngeal Cancers
SPECT-CT Guided ELEctive Contralateral Neck Treatment in Lateralized Oropharyngeal Cancer
Oropharyngeal cancer (OPC) is the most common type of head and neck cancer. The current standard treatment for this cancer is radiotherapy (RT) of the tumour and lymph nodes of both sides of the neck, combined with concurrent…
- Conditions
- Oropharyngeal Squamous Cell Carcinoma, Oropharyngeal Cancers, Oropharyngeal Carcinoma, Head and Neck
- Trial name
- SELECT-FR (NCT07241273)
- Testing
- Lymphatic mapping with SPECT-CT, Bilateral neck radiotherapy, Ipsilateral neck radiotherapy & SPECT-CT guided contralateral neck radiotherapy
- Where
- 12 sites in France
- Volunteers
- 128 people
- Sponsor
- UNICANCER
Pseudoarthrosis of Bone
SPECT/CT Bone Scan Quantification Surgery
The hypothesis of our study is that SPECT/CT bone scan fixation quantified by SUVMAX on a CZT solid state camera preoperatively would identify good responders to lumbar arthrodesis surgery.
- Trial name
- PERQUAL (NCT05183542)
- Testing
- Bone scan
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Central Hospital, Nancy, France
Prostatic Cancer
Contribution of the VERITON-CT Camera in Prostate Bone Radiostereotaxy
Stereotactic radiotherapy enables bone metastases to be treated with highly precise irradiation beams, enabling small targets to be irradiated.
- Trial name
- VERIOS (NCT06439784)
- Testing
- whole body SPECT/CT
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Henri Becquerel
Lung Cancer
A Phase 3 Study of 99mTC-EC-DG SPECT/CT Versus PET/CT in Lung Cancer
The purpose of this study is to determine if the images of the primary lesions of lung cancer and any metastatic lesions seen from the investigational SPECT/CT 99mTC-EC-DG scans are the same as the PET/CT 18F-FDG scans.
- Trial name
- NCT01394679
- Testing
- (99m Tc) ECDG (Ethylenedicysteine-Deoxyglucose), 18 F FDG followed by PET/CT imaging
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Cell>Point LLC
HCC, SPECT-CT
Preliminary Evaluation of Clinical Application of SPECT Imaging Targeting GPC3
This project will target patients with highly clinically suspected or histopathology diagnosed hepatocellular carcinoma (HCC) using targeted GPC3-specific imaging agents (e.g.
- Trial name
- NCT07353333
- Testing
- 131I-aGPC3
- Where
- China
- Volunteers
- 6 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Primary Breast Cancer
Evaluation of Different Types of HER2 Expression in Breast Cancer Using [99mTc]Tc -ZHER2:4107
The study should evaluate the [99mTc]Tc -ZHER2:4107 accumulation in primary tumour of breast cancer patients with different HER2 expression
- Trial name
- NCT07292571
- Testing
- Injection of [99mTc]Tc-ZHER2:4107, SPECT/CT
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Osteoarthritis Ankle, Osteoarthritis
SPECT-CT vs MRI for the Diagnosis of Osteoarthritis in the Foot and Ankle
The diagnose of symptomatic osteoarthritis in the ankle, mid- and hind foot remains challenging. There is no gold standard for the work-up and various hospitals use different protocols.
- Trial name
- NCT05912153
- Testing
- SPECT/CT, MRI
- Where
- Netherlands
- Volunteers
- 132 people
- Sponsor
- Martini Hospital Groningen
Primary Breast Cancer
[99mTc]Tc-DB8 Accumulation in Primary Tumor in Breast Cancer With Positive and Negative Estrogen Receptor Expression
The study should evaluate the [99mTc]Tc-DB8 accumulation in primary tumour of breast cancer patients with positive and negative estrogen receptor expression.
- Trial name
- NCT07275463
- Testing
- [99mTc]Tc-DB8
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Prostate Cancer Metastatic Disease
Prospective Evaluation of Imaging Response Biomarkers During [177Lu]Lu-PSMA in Metastatic Castration-resistant Prostate Cancer
Lutetium-177 (177Lu) prostate-specific membrane antigen (177Lu-PSMA) is a radiolabelled small-molecule inhibitor that binds with high affinity to PSMA and delivers β particle radiation.
- Trial name
- 68Ga-PSMA (NCT06828263)
- Where
- France
- Volunteers
- 130 people
- Sponsor
- University Hospital, Grenoble