Clinical trials: SRP, active
Periodontitis, Diabetes Mellitus Type 2
Effect of Arestin-Enhanced SRP on Periodontal and Glycemic Outcomes in Diabetics
Periodontitis is a prevalent chronic inflammatory disease that exacerbates systemic inflammation and poses challenges for glycemic control in diabetic patients.
- Trial name
- NCT07298057
- Testing
- local antibiotic application of topical minocycline, Scaling and Root Planing
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Case Western Reserve University
Periodontal Diseases, Periodontitis
Evaluation Of The Efficacy Of Subgingival Application Of Lovastatin Gel As An Adjunct To Non-Surgical Treatment Of Periodontitis In Generally Healthy Smokers And Non-Smokers Patients in Central Europe.
The aim of the study is to evaluate how a gel (1.2% lovastatin) applied under the gum improves the results of classic periodontal treatment (SRP-scaling, root planing).
- Conditions
- Periodontal Diseases, Periodontitis, Periodontal Disease, Smokers
- Trial name
- RCT (NCT07282756)
- Testing
- Subgingival application of 1.2% lovastatin
- Where
- Poland
- Volunteers
- 44 people
- Sponsor
- Medical University of Silesia
Stage II, Grade B Periodontitis, Chronic Periodontitis
Metformin Versus Chlorhexidine Gel as Adjuncts to Scaling and Root Planing in Stage II Grade B Periodontitis
This clinical trial is designed to evaluate two locally delivered gels, metformin and chlorhexidine, as adjunctive therapies to scaling and root planing (SRP) in patients with Stage II, Grade B periodontitis.
- Trial name
- MET-CHX Perio (NCT07215156)
- Testing
- Arm 1 Scaling and Root Planing (SRP), Arm 2 Metformin Gel 1% (locally delivered), Arm 3 Chlorhexidine Gel 0.2% (locally delivered)
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Periodontal Disease, Periodontitis
Evaluation of the Influence of PRF (Platelet-rich Fibrin) on the Clinical Parameters and the Concentration of Selected Inflammation Mediators in GCF (Gingival Crevice Fluid) of Patients With Periodontitis
Assessment of the influence of injectable platelet-rich fibrin (i-PRF) on the clinical parameters and the inflammation mediators levels in the gingival crevicular fluid (GCF) in patients with periodontitis.
- Trial name
- PRFperio (NCT06920849)
- Testing
- SRP+iPRF, SRP
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Medical University of Bialystok
Stroke, Cerebrovascular Accident
Cardiac Rehabilitation of Stroke Survivors (SRP-CROSS)
This study examines the effectiveness of the cardiac rehabilitation program for stroke patients. The study will examine if patients with stroke, who receive cardiac rehabilitation in addition to their standard of care treatments…
- Trial name
- SRP-CROSS (NCT05651945)
- Testing
- Cardiac rehabilitation program
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Hackensack Meridian Health
Refractory Immune-mediated Necrotizing Myopathy
A Phase I/II Study of Eque-cel in Subjects Withimmune-mediated Necrotizing Myopathy
This is an open-label, single-arm Phase I/II clinical study to evaluate the efficacy and safety of Eque-cel Injection in patients with refractory immune-mediated necrotizing myopathy.
- Trial name
- NCT07752264
- Testing
- Equecabtagene Autoleucel Injection (Eque-cel)
- Where
- 4 sites in China
- Volunteers
- 27 people
- Sponsor
- Nanjing IASO Biotechnology Co., Ltd.
Periodontitis, Periodontal Disease
Photodynamic Therapy as an Adjunct in Periodontal Treatment
This study aims to evaluate the clinical effectiveness of antimicrobial photodynamic therapy (aPDT) as an adjunct to scaling and root planing (SRP) in the treatment of periodontitis.
- Trial name
- PDT-PERIO (NCT07633405)
- Testing
- Scaling and Root Planing, Antimicrobial Photodynamic Therapy
- Where
- Ecuador
- Volunteers
- 30 people
- Sponsor
- Universidad Catolica Santiago de Guayaquil
Periodontitis (Stage 3)
A Clinical Trial Comparing 2x/Day for 30-minutes Use of the Emanate Perio PODS Post-SRP to a Control Group Post-SRP.
The goal of this clinical trial is to compare safety and to see if individuals with generalized stage III periodontitis that are given a periodontal hydrogel dressing on a wound healing after plaque and tartar have been removed…
- Trial name
- NCT06914596
- Testing
- Emanate Perio PODS
- Where
- 9 sites in United States
- Volunteers
- 72 people
- Sponsor
- McGuire Institute
Periodontitis
Influence of SRP With MM on the Composition and Functional Characteristics of Subgingival Microbiome Communities
The purpose of this study is to characterize the effect of minocycline microspheres (MM) administered as an adjunct to scaling and rooting planning (SRP) on the subgingival community composition and metatranscriptome functional…
- Trial name
- NCT05422742
- Testing
- SRP + MM, Scaling and Root Planing (SRP)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- West Virginia University
Periodontal Pocket
Evaluation of 2%Bromelain Gel With 0.2%CHX Gel as Subgingival LDD Following SRP in Stage II/III and Grade B Periodontitis -A RCT
The current study is a prospective randomised study Evaluation of 2%Bromelain Gel With 0.2%Chlorhexidine Gel as Subgingival Local Drug Delivery Following Scaling and Root Planing in Stage II/III and Grade B Periodontitis
- Trial name
- NCT06505759
- Testing
- Bromelain gel, chlorhexidine gel, SRP
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital