Clinical trials: ST Segment Elevation Acute Myocardial Infarction
Acute Myocardial Infarction
PAclitaxel-eluting Balloon in Primary PCI in Amsterdam; Pilot Study
This clinical evaluation will study the feasibility and safety of a CE-marked paclitaxel-eluting balloon in primary PCI in patients with a STEMI.
- Trial name
- PAPPA-pilot (NCT01274728)
- Testing
- Percutaneous coronary intervention
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Onze Lieve Vrouwe Gasthuis
Acute Myocardial Infarction
TandemHeart to Reduce Infarct Size (TRIS Trial)
The purpose of this study is to determine if a device known as the TandemHeart® System (TandemHeart) can help limit heart damage and reduce serious complications after a certain type of heart attack (acute ST elevation anterior…
- Trial name
- TRIS (NCT02164058)
- Testing
- TandemHeart System, Percutaneous coronary intervention
- Sponsor
- CardiacAssist, Inc.
Acute Coronary Syndrome
Influence of Intensive Lipid Lowering Treatment Compared to Moderate Lipid Lowering Treatment on Plaque Composition in Patients With ST-Segment Elevation Myocardial Infarction (MI)
In patients with ST-segment elevation acute myocardial infarction (STEMI) increased LDL-cholesterol reduction (rosuvastatin 40 mg) will provide incremental plaque stabilization (changes in plaque composition) and plaque…
- Trial name
- VIRHISTAMI (NCT01058915)
- Testing
- Rosuvastatin 5mg, Rosuvastatin 40mg
- Where
- Denmark
- Volunteers
- 87 people
- Sponsor
- Odense University Hospital
Myocardial Infarction
Complete Infarct Related Artery Revascularization in Acute Myocardial Infarction
Objective of this registry study is to compare strategy of complete vs. target lesion-only primary PCI (percutaneous coronary intervention) in IRA (infarct related artery) in STEMI (ST elevation myocardial infarction) patients.
- Trial name
- CORAMIreg (NCT01642784)
- Testing
- Primary PCI of culprit lesion in IRA with drug eluting stent (DES), Primary PCI of culprit lesion in IRA with drug eluting stent (DES) and PCI of the other critical lesion in IRA with another DES
- Where
- 8 sites in Poland, Slovenia
- Volunteers
- 100 people
- Sponsor
- Fundacja Ośrodek Badań Medycznych
Acute Myocardial Infarction
Myocardial Protection With Adenosine During Primary Percutaneous Coronary Intervention in Pts With STEMI
OBJECTIVE: to evaluate the safety and efficacy of a brief intracoronary infusion of ADO applied at the time of reperfusion to limit infarct size and LV remodelling in patients with ACSST submitted to primary ACTP.
- Trial name
- PROMISE (NCT00781404)
- Testing
- Adenosine
- Where
- Spain
- Volunteers
- 201 people
- Sponsor
- David Garcia-Dorado
Acute ST-elevation Myocardial Infarction
the Effect of Prolonged Inflation Time During Stents Deployment for ST-elevation Myocardial Infarction
The purpose of this study is to determine whether prolonged inflation time on drug-eluting stents deployment for ST-elevation myocardial Infarction was better than conventional stents deployment.
- Trial name
- NCT03199014
- Testing
- deploying the Drug-eluting Stents with a prolonged time, deploying the Drug-eluting Stents with a conventional time
- Where
- China
- Volunteers
- 60 people
- Sponsor
- West China Hospital
Acute Myocardial Infarction, Congestive Heart Failure
IK-5001 for the Prevention of Remodeling of the Ventricle and Congestive Heart Failure After Acute Myocardial Infarction
The primary objective is to evaluate the safety and effectiveness of the IK-5001 device for the prevention of ventricular remodeling and congestive heart failure when administered to subjects who had successful percutaneous…
- Conditions
- Acute Myocardial Infarction, Congestive Heart Failure, ST-Elevation Myocardial Infarction
- Trial name
- PRESERVATION-1 (NCT01226563)
- Testing
- IK-5001, Saline Solution
- Where
- 82 sites in United States, Australia and 7 more
- Volunteers
- 303 people
- Sponsor
- Bellerophon BCM LLC
STEMI
Cangrelor Following Ticagrelor Loading vs Ticagrelor Loading Alone in STEMI
Platelets and thrombus formation play a key role in the pathogenesis of acute coronary artery occlusion and subsequent myocardial infarction.
- Trial name
- NCT02943369
- Testing
- Ticagrelor 180 mg loading dose, Cangrelor 30 mcg/kg bolus + 4 mcg/kg/min
- Where
- Greece
- Volunteers
- 30 people
- Sponsor
- Attikon Hospital
Acute Myocardial Infarction
Alpha-1 Anti-Trypsin (AAT) Treatment in Acute Myocardial Infarction
Acute myocardial infarction is characterized by an intense inflammatory response. The degree of the response influences clinical outcome, with 'more' inflammation promoting heart failure.
- Trial name
- VCU-Alpha1RT (NCT01936896)
- Testing
- Alpha 1-Antitrypsin
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Virginia Commonwealth University
ST Segment Elevation Myocardial Infarction
Distal Radial Access for Primary PCI in STEMI Patients to Prevent RAO
Randomized-controlled trial to compare early radial artery occlusion via distal vs. conventional transradial access among ST segment elevation myocardial infarction patients for primary percutaneous coronary intervention.
- Trial name
- RAPIDIII (NCT05461781)
- Testing
- distal radial access, conventional transradial access
- Where
- China
- Volunteers
- 512 people
- Sponsor
- Beijing Luhe Hospital
ST-elevation MI, Hypothermia
Evaluation of Ultrafast Hypothermia Before Reperfusion in STEMI Patients
This study will look at the safety of treating patients with heart attack with mild hypothermia induced using a system of automated peritoneal lavage.
- Trial name
- VELOCITY (NCT01655433)
- Testing
- Velomedix APLS device, No Hypothermia Treatment
- Where
- 7 sites in United States, Canada
- Volunteers
- 54 people
- Sponsor
- Velomedix, Inc.
Angina, Unstable, Non-ST-Segment Elevation Myocardial Infarction
OCT Based Edge and In-stent Vascular Response After Cordimax Stent in patIents With NSTE-ACS
This study evaluates the completeness of strut coverage and vessel wall response, at different time points (3-6-12 Months), following CordimaxTM stent implantation in patients with non-ST elevation acute coronary syndrome
- Trial name
- NCT02868203
- Testing
- OCT, eLuting stent
- Volunteers
- 80 people
- Sponsor
- Xijing Hospital
STEMI - ST Elevation Myocardial Infarction, Percutaneous Coronary Intervention
Non Culprit Functional Evaluation With 3D Angio QFR in STEMI PCI Procedure
Reliability of 3D angio QFR functional evaluation of all non culprit lesions >50% in STEMI patients during first acute procedure
- Conditions
- STEMI - ST Elevation Myocardial Infarction, Percutaneous Coronary Intervention, Coronary Artery Disease
- Trial name
- NCT02998853
- Testing
- QFR measurement by dedicated workstation on xrays angio selected runs
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Azienda Ospedaliera Sant'Anna e San Sebastiano
Myocardial Infarction, Myocardial Ischemia
OPTIMISER Registry - A Prospective Cohort Study to Describe the OPTIMal Management and Outcomes of PatIents PreSEnting With Acute MyocaRdial Infarction
The purpose of the OPTIMISER Registry is to prospectively and retrospectively collect baseline, clinical and procedural data in patients who present with AMI and are treated with PCI as well as prospectively collect the clinical…
- Conditions
- Myocardial Infarction, Myocardial Ischemia, STEMI, NSTEMI
- Trial name
- OPTIMISER (NCT04988672)
- Where
- Switzerland
- Volunteers
- 4,000 people
- Sponsor
- Luzerner Kantonsspital
Acute Coronary Syndromes
Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry
The primary objective of the UPSTREAM Registry is to address the data gap regarding the course of NSTEMI (Non-ST-Elevation Myocardial Infarction)between ED (Emergency Department) arrival and diagnostic angiography in detail, by…
- Trial name
- NCT02271022
- Testing
- Non-Interventional Study
- Where
- 55 sites in United States
- Volunteers
- 2,000 people
- Sponsor
- AstraZeneca
Acute Myocardial Infarction
Paced Electrocardiogram Requiring Fast Emergent Coronary Therapy (PERFECT) Study
The number of patients with cardiovascular implantable electronic devices (CIED), including ventricular pacemakers, continues to increase.
- Trial name
- PERFECT (NCT02765477)
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- Hennepin County Medical Center, Minneapolis
Coronary Artery Disease, Atherosclerosis
Drug-eluting Balloon in Acute Myocardial Infarction
The investigators hypothesize that patients with Acute ST Elevation Myocardial Infarction may benefit from primary angioplasty with use of a drug eluting balloon/bare metal stent combination without impairing the process of…
- Conditions
- Coronary Artery Disease, Atherosclerosis, Thrombosis, Acute Myocardial Infarction
- Trial name
- DEB-AMI (NCT00856765)
- Testing
- Drug eluting balloon, Bare metal stent, Drug eluting stent
- Where
- 2 sites in Italy, Netherlands
- Volunteers
- 150 people
- Sponsor
- UMC Utrecht
Coronary Artery Disease, Myocardial Ischemia
BIOFLOW-III Belgium Satellite Registry
This registry is a clinical post-market evaluation of the Orsiro LESS in subjects requiring coronary revascularization with Drug Eluting Stents (DES).
- Trial name
- NCT01831336
- Where
- 8 sites in Belgium
- Volunteers
- 332 people
- Sponsor
- Biotronik Belgium NV
Acute Coronary Syndrome
Ticagrelor Versus Clopidogrel in Myocardial Salvage in Patients With STEMI Undergoing Primary PCI
Therefore, in this study, we try to evaluate the impact of clopidogrel loading dose 300mg vs. ticagrelor 180 mg on myocardial injury as measured by contrast-enhanced magnetic resonance imaging (CE-MRI) in STEMI patients…
- Trial name
- NCT02792712
- Testing
- Ticagrelor, Clopidogrel
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Myocardial Infarction
A Structuralised Sick-leave Program Compared to Usual Care Sick Leave Management in Patients After an Acute Myocardial Infarction
In this study the investigators aim at comparing the effect on quality of life and the cost-effectiveness of a structuralised sick-leave program compared to usual care sick leave management in patients after an acute non ST…
- Trial name
- NCT01108653
- Testing
- Usual care sick-leave management, Structuralised sick-leave program
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Oslo University Hospital