Clinical trials: ST Segment Elevation Myocardial Infarction (STEMI)
Type 2 Diabetes, Acute Myocardial Infarction
Glucose Monitoring After Acute Myocardial Infarct in People With Diabetes
Glucose monitoring after Acute Myocardial infarct in people with diabetes is a Dexcom funded study that is investigating whether the use of continuous glucose monitors (Dexcom ONE model) in people with type 2 diabetes facilitates…
- Conditions
- Type 2 Diabetes, Acute Myocardial Infarction, Acute Myocardial Infarction With ST Elevation, Diabetes Complications
- Trial name
- GLAM (NCT05431296)
- Testing
- Dexcom ONE Continuous Glucose Monitoring System
- Where
- United Kingdom
- Volunteers
- 160 people
- Sponsor
- Imperial College London
Acute Myocardial Infarction
Norwegian Study on District Treatment of ST-Elevation Myocardial Infarction
In the district areas of Norway patients with acute myocardial infarction with ST-elevation, are treated with thrombolysis. An increasing part of them receives thrombolysis before arrival to the local hospital.Usually these…
- Trial name
- NCT00161005
- Testing
- PCI
- Where
- Norway
- Volunteers
- 266 people
- Sponsor
- Ullevaal University Hospital
Multi Vessel Coronary Artery Disease, STEMI
Assessing Microvascular Resistance Via IMR To Predict Cumulative Outcome in STEMI Patients Undergoing Primary PCI
The purpose of this study is to assess whether the Index of Microcirculatory Resistance (IMR) can be considered a prognostic predictor for the occurrence of events at one year of follow up after primary Percutaneous Coronary…
- Trial name
- AMICRO (NCT02325973)
- Testing
- PressureWire Certus guidewire
- Where
- 14 sites in Italy
- Volunteers
- 242 people
- Sponsor
- Abbott Medical Devices
Acute Myocardial Infarction
Paced Electrocardiogram Requiring Fast Emergent Coronary Therapy (PERFECT) Study
The number of patients with cardiovascular implantable electronic devices (CIED), including ventricular pacemakers, continues to increase.
- Trial name
- PERFECT (NCT02765477)
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- Hennepin County Medical Center, Minneapolis
Coronary Artery Ectasia, Acute Coronary Syndromes (ACS)
Multicenter Trial of Antithrombotic Strategies in Acute Coronary Syndrome With Coronary Artery Ectasia
Coronary artery ectasia (CAE) is a condition in which a coronary artery becomes abnormally dilated, measuring at least 50% larger than the adjacent normal segment.
- Conditions
- Coronary Artery Ectasia, Acute Coronary Syndromes (ACS), STEMI - ST Elevation Myocardial Infarction, NSTEMI - Non-ST Segment Elevation Myocardial Infarction (MI)
- Trial name
- OVER-TIME II (NCT07511257)
- Testing
- Aspirin 100 mg, Clopidogrel 75 mg, Rivaroxaban 15 mg
- Where
- Mexico
- Volunteers
- 326 people
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
ST Elevation Myocardial Infarction
Remote Ischemic Conditioning With Local Ischemic Postconditioning in High-Risk ST-elevation Myocardial Infarction
The RIP-HIGH trial is a two-arm randomized controlled trial aiming to compare the impact of combined remote ischemic conditioning (RIP) and local ischemic postconditioning (PostC) vs.
- Trial name
- RIP-HIGH (NCT04844931)
- Testing
- RIC + PostC + Standard PCI, Standard PCI
- Where
- 11 sites in Austria, Germany
- Volunteers
- 250 people
- Sponsor
- Helios Health Institute GmbH
ST-elevation Myocardial Infarction
The Short- and Long Term Outcomes of Early Routine PCI With the Standard Treatment in Low-intermediate Risk ST-elevation Myocardial Infarction Patients Who Successfully Fibrinolysis.
1. Objective: To evaluate short- and long-term in the STEMI patients who successfully thrombolysis with early routine and delay percutaneous coronary intervention in low-intermediate risk patients. 2.
- Trial name
- NCT02131103
- Testing
- Percutaneous coronary intervention
- Where
- Thailand
- Volunteers
- 130 people
- Sponsor
- Chiang Mai University
Myocardial Infarction
Incheon-Bucheon Cohort of Patients Undergoing Primary PCI for Acute STEMI
INcheon-Bucheon cohorT of patients undERgoing primary percutaneous coronary intervention for acute ST-ELevation myocardiaL infARction (INTERSTELLAR) registry is a retrospective, observational, 4-regional-hospital based registry…
- Trial name
- NCT02804958
- Testing
- STEMI treated with primary PCI
- Where
- 4 sites in South Korea
- Volunteers
- 1,537 people
- Sponsor
- Gachon University Gil Medical Center
ST Elevation Myocardial Infarction, Coronary Microvascular Dysfunction
Assessment of Coronary Microvascular Dysfunction After STEMI Using Continuous Saline Thermodilution
The goal of this observational study to measure the heart's microvascular function in the setting of a myocardial infarction (MI), or heart attack, using a method called continuous saline thermodilution (CST).
- Conditions
- ST Elevation Myocardial Infarction, Coronary Microvascular Dysfunction, Microvascular Obstruction
- Trial name
- ConMICRO (NCT06795035)
- Testing
- Continuous Saline Thermodilution
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- The Cleveland Clinic
ST-Elevation Myocardial Infarction
PraSugrel vs TicagrElor in ST-Elevation Myocardial Infarction paTients With Diabetes Mellitus
Dual antiplatelet therapy is essential in patients following ST-Elevation myocardial infarction (STEMI) with percutaneous coronary intervention (PCI) and drug eluting stent implantation.
- Trial name
- RESET 2D (NCT01531114)
- Testing
- ticagrelor, prasugrel
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Gennaro Sardella
Acute Myocardial Infarction, Coronary Artery Disease
Physiology-guided vs Angiography-guided Non-culprit Lesion Complete Revascularization for Acute MI & Multivessel Disease
COMPLETE-2 is a prospective, multi-centre, randomized controlled trial comparing a strategy of physiology-guided complete revascularization to angiography-guided complete revascularization in patients with acute ST-segment…
- Trial name
- COMPLETE-2 (NCT05701358)
- Testing
- Physiology-guided NCL PCI, Angiography-guided NCL PCI
- Where
- 138 sites in United States, Australia and 18 more
- Volunteers
- 5,100 people
- Sponsor
- Population Health Research Institute
Optical Coherence Tomography, Dual Antiplatelet Therapy
OCT or Angiography Guided De-escalation of DAPT
Optical coherence tomography (OCT) offers a high-resolution intravascular imaging modality to accurately assess vessel and lumen geometry and identify the hallmark of a culprit lesion including plaque disruption and thrombus.
- Conditions
- Optical Coherence Tomography, Dual Antiplatelet Therapy, Antiplatelet De-escalation, Neointimal Coverage
- Trial name
- NCT06339021
- Testing
- OCT-guided PCI, Conventional angiography-based PCI, DAPT de-escalation
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shenyang Northern Hospital
Cardiac Rehabilitation
The Use of Contextualised Body Data in Cardiac Rehabilitation (CR)
KiCS1 study : Digital health for current hospital- based Cardiac rehabilitation programmes to increase effectiveness and patient outcomes.
- Trial name
- KiCS1 (NCT05492526)
- Testing
- Ki Monitor without feedback, Ki monitor with contextualised data feedback
- Where
- United Kingdom
- Volunteers
- 130 people
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Coronary Artery Disease, Atherosclerosis
Drug-eluting Balloon in Acute Myocardial Infarction
The investigators hypothesize that patients with Acute ST Elevation Myocardial Infarction may benefit from primary angioplasty with use of a drug eluting balloon/bare metal stent combination without impairing the process of…
- Conditions
- Coronary Artery Disease, Atherosclerosis, Thrombosis, Acute Myocardial Infarction
- Trial name
- DEB-AMI (NCT00856765)
- Testing
- Drug eluting balloon, Bare metal stent, Drug eluting stent
- Where
- 2 sites in Italy, Netherlands
- Volunteers
- 150 people
- Sponsor
- UMC Utrecht
ST-segment Elevation Myocardial Infarction
Phase 2 Study to Evaluate the Efficacy, Safety and PK of Intravenous Single Injection LC28-0126 Immediately Before PCI in STEMI Patients
Evaluate the efficacy, Safety and Pharmacokinetics of Intravenous single injection LC28-0126 immediately before PCI (Percutaneous Coronary Intervention) in Patients with STEMI (ST-segment Elevation Myocardial Infarction)
- Trial name
- NCT02070471
- Testing
- LC28-0126 Dose A, LC28-0126 Dose B, LC28-0126 Dose C
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- LG Life Sciences
Acute Myocardial Infarction
FFR Versus Angiography-Guided Strategy for Management of AMI With Multivessel Disease
The aim of the study is to compare clinical outcomes following fractional flow reserve (FFR)-guided versus angiography only guided strategy in treatment of non-infarction related artery (non-IRA) stenosis in patients with acute…
- Trial name
- FRAME-AMI (NCT02715518)
- Testing
- PCI using 2nd generation drug-eluting stent
- Where
- South Korea
- Volunteers
- 1,292 people
- Sponsor
- Samsung Medical Center
Acute Coronary Syndrome, Depression
MBCT Delivered Via Group Videoconferencing for ACS Patients With Elevated Depression Symptoms
The objective of this study is to identify Acute Coronary Syndromes (ACS) patients' specific needs and preferences for depression treatment via in-person or virtual individual interviews to (a) guide MBCT adaptation; and identify…
- Conditions
- Acute Coronary Syndrome, Depression, Myocardial Infarction, Unstable Angina
- Trial name
- NCT03878160
- Testing
- Individual Interview
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Cardiac Rupture
Clinical Risk Score Predicting the Cardiac Rupture in Patients With ST-elevation Myocardial Infarction
The purpose of this study is to validate a practical risk score to predict the mechanical complication of ST-elevation myocardial infarction (STEMI).
- Trial name
- NCT02484326
- Testing
- Grouping by different risk stratification
- Where
- China
- Volunteers
- 3,779 people
- Sponsor
- Chinese PLA General Hospital
Coronary Artery Disease, Acute Coronary Syndrome
BIOSTEMI Extended Survival
The objective of the BIOSTEMI ES study is to assess the long-term clinical outcomes with the Orsiro ultrathin-strut biodegradable polymer sirolimus-eluting stent compared to the Xience thin-strut durable polymer…
- Trial name
- BIOSTEMI ES (NCT05484310)
- Where
- 10 sites in Switzerland
- Volunteers
- 1,300 people
- Sponsor
- University Hospital, Geneva
ST Elevation Myocardial Infarction, Arrhythmia Ventricular
Different Reperfusion Timing and Ventricular Arrhythmias in STEMI Patients
The aim of this study was to investigate the association between different reperfusion timing and ventricular arrhythmias (VAs) to provide evidence for clinical decision-making for patients with ST-segment elevation myocardial…
- Trial name
- NCT04660474
- Where
- China
- Volunteers
- 517 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
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