Clinical trials: ST Segment Elevation Myocardial Infarction (STEMI)
ST-elevation Myocardial Infarction
Cost-effectiveness of Remote Ischemic Conditioning as an Adjunct to Primary Percutaneous Coronary Intervention
The aim of this study is to investigate the cost-effectiveness of remote ischemic conditioning as an adjunct to primary percutaneous coronary intervention from the perspective of a Danish healthcare system.
- Trial name
- NCT02431338
- Testing
- Remote ischemic conditioning
- Where
- Denmark
- Volunteers
- 333 people
- Sponsor
- University of Aarhus
Acute Myocardial Infarction
Intervention of Suxiao Jiuxin Pill on Instability of Vulnerable Plaque in Acute Myocardial Infarction
The incidence of cardiovascular disease is still high in China under the condition of non-standard treatment of Western medicine.
- Trial name
- NCT05466968
- Testing
- Suxiao Jiuxin Pills
- Where
- China
- Volunteers
- 116 people
- Sponsor
- Xiaolu Li
ACS - Acute Coronary Syndrome
European Unified Registries for Heart Care Evaluation and Randomised Trials Italy
Major advances in cardiovascular medicine have been driven by innovations in basic research in biological and technical sciences.
- Trial name
- EuroHeart ITA (NCT07283809)
- Testing
- Adherence to European Society of Cardiology (ESC) quality indicators
- Where
- 57 sites in Italy
- Volunteers
- 5,000 people
- Sponsor
- Heart Care Foundation
Anterior Myocardial Infarction
A Research Study to Evaluate the Safety and Preliminary Efficacy of SGC001 in Patients With Myocardial Infarction
The research study is being done to see if SGC001 can be used to treat people scheduled to undergo percutaneous coronary intervention for Anterior ST-segment Elevation Myocardial Infarction.
- Trial name
- NCT07091929
- Testing
- SGC001
- Where
- 4 sites in China
- Volunteers
- 38 people
- Sponsor
- Beijing Sungen Biomedical Technology Co., Ltd
Non-ST-elevation Myocardial Infarction, Multivessel Coronary Artery Disease
Complete Revascularization Versus Culprit Lesion Only PCI in NSTEMI
Prospective, randomized, controlled, multicenter, open-label trial to study whether multivessel percutaneous coronary intervention (PCI) is superior over culprit-lesion only PCI in patients with non-ST-segment elevation…
- Trial name
- CompleteNSTEMI (NCT05786131)
- Testing
- Culprit-lesion revascularization, Non-culprit-lesion revascularization
- Where
- 58 sites in Austria, Germany
- Volunteers
- 3,390 people
- Sponsor
- Leipzig Heart Science gGmbH
STEMI - ST Elevation Myocardial Infarction, Unstable Angina
Evaluation of Short Term Outcome of Different Bifurcation Stenting Techniques at Assuit University Cath. Lab
Primary aim: evaluation of the short term outcome of different techniques used in bifurcational coronary arteries intervention regarding major adverse cardiac event (MACE): cardiac death, myocardial infarction, target vessel…
- Trial name
- NCT03266289
- Volunteers
- 50 people
- Sponsor
- MA Abdelreheem
Coronary Heart Disease
After Eighty Study
The rationale of the present clinical trial is to study whether an invasive strategy in clinical stable patients over 80 years with NSTEMI/UAP may improve rates of death, reinfarction, stroke, need of urgent revascularisation…
- Trial name
- NCT01255540
- Where
- Norway
- Volunteers
- 492 people
- Sponsor
- Oslo University Hospital
ST Elevation Myocardial Infarction
The Eosinophils Percentage Predicts In-hospital Major Adverse Cardiac Events in STEMI Patients After PCI
Eosinophils (EOS) in peripheral blood are significantly decreased in ST-segment elevation myocardial infarction (STEMI) and the reduced EOS indicates severe myocardial damage.
- Trial name
- NCT03740776
- Volunteers
- 2 people
- Sponsor
- Dongying Zhang
ST Elevation Myocardial Infarction
Efficacy and Safety of a Half-dose Bolus of r-SAK Prior to Primary PCI in ST-elevation Myocardial Infarction
As an effective treatment for acute ST-segment elevation myocardial infarction (STEMI), early reperfusion may reduce the infarct size and improve the prognosis of patients.
- Trial name
- OPTIMA-6 (NCT05410925)
- Testing
- Recombinant staphylokinase
- Where
- 61 sites in China
- Volunteers
- 2,260 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Acute Myocardial Infarction
Safety Study of Allogeneic Mesenchymal Precursor Cell Infusion in Myocardial Infarction
This was a double-blind, randomized, placebo-controlled study that was designed to enroll a total of 225 participants with de novo anterior wall acute ST-segment elevation myocardial infarction (STEMI) due to a lesion of the left…
- Trial name
- AMICI (NCT01781390)
- Testing
- Mesenchymal Precursor Cells (MPC) 12.5 M, Mesenchymal Precursor Cells (MPC) 25 M
- Volunteers
- 106 people
- Sponsor
- Mesoblast, Inc.
ST Segment Elevation Myocardial Infarction
China STEMI-PCI Program
1. Registration 2. Performing in three stages 3. Major aim: Much more and standard reperfusion therapy in STEMI patients
- Trial name
- NCT01716884
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Peking University First Hospital
Cardiovascular Diseases
Bioabsorbable Scaffold vs Drug-coated Balloon for Coronary de Novo Lesions in STEMI: Prospective Observational Trial
a prospective, single center, observational clinical trail. Aim to to compare the efficacy and safety of the Bioabsorbable scaffold (BRS) Neovas BRS and Drug-coating balloon (DCB) in the treatment of STEMI patients with coronary…
- Trial name
- NeovasvsDCB (NCT04565561)
- Testing
- Neovas BRS or DCB
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Shenzhen People's Hospital
Myocardial Infarction
Postconditioning in ST-elevation Myocardial Infarction
Study objectives: To assess the effects of postconditioning on infarct size in patients with ST-elevation infarction referred to PCI. Study design: Prospective, randomized, open-label study with blinded endpoint evaluation.
- Trial name
- POSTEMI (NCT00922675)
- Testing
- Postconditioning, Control intervention
- Where
- Norway
- Volunteers
- 272 people
- Sponsor
- Oslo University Hospital
Acute Coronary Syndrome, Myocardial Infarction
Utilization of Diagnostic Ultrasound in the Detection and Therapy of Acute Coronary Syndromes
The study will see if mechanical impulses delivered by an echocardiographic probe during a continuous infusion of MRX 801 are capable of improving blood flow in smaller heart vessels in patients with acute coronary syndromes.
- Trial name
- NCT00955136
- Testing
- Use of intermittent high MI impulses during echocardiogram
- Sponsor
- University of Nebraska
ST-elevation Myocardial Infarction
Early Treatment With Evolocumab in Patients With ST-elevation Myocardial Infarction
This is a prospective, multi-centre, open label, randomised study of Phase II that enrolls patients hospitalized with a diagnosis of ST-elevation myocardial infarction (STEMI), comparing Evolocumab versus Standard of Care.
- Trial name
- ExOTIC (NCT04303377)
- Testing
- Evolocumab
- Where
- Italy
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
ST Elevation Myocardial Infarction
Supplemental Oxygen in Catheterized Coronary Emergency Reperfusion
The aim of SOCCER is to evaluate the effects of treatment with supplemental O2 before and during acute balloon angioplasty (PCI) for patients with ST-elevation myocardial infarction (STEMI).
- Trial name
- SOCCER (NCT01423929)
- Testing
- Oxygen, Room air
- Where
- 3 sites in Sweden
- Volunteers
- 100 people
- Sponsor
- Region Skane
Myocardial Infarction, Ischemia
Smartphone Twelve-Lead ECG Utility In ST-Elevation Myocardial Infarction II
AliveCor (www.alivecor.com) has developed several electrocardiogram (ECG) devices that interface with iOS and Android smartphones and tablets via various Kardia apps.
- Conditions
- Myocardial Infarction, Ischemia, Myocardial Ischemia, Heart Diseases
- Trial name
- STLEUISII (NCT06271577)
- Testing
- AliveCor 12-lead ECG
- Where
- 4 sites in United States, United Kingdom
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- AliveCor
Coronary Artery Disease, Coronary Stenosis
ILUMIEN IV: OPTIMAL Percutaneous Coronary Intervention (PCI)
The objective of this prospective, single-blind clinical investigation is to demonstrate the superiority of an Optical Coherence Tomography (OCT)-guided stent implantation strategy as compared to an angiography-guided stent…
- Conditions
- Coronary Artery Disease, Coronary Stenosis, Atherosclerosis, STEMI
- Trial name
- NCT03507777
- Testing
- Coronary PCI guided by OCT, Coronary PCI guided by Angiography
- Where
- 90 sites in United States, Australia and 18 more
- Volunteers
- 2,487 people
- Sponsor
- Abbott Medical Devices
STEMI - ST Elevation Myocardial Infarction
Use of the Methoxyflurane as Pain-killer in the Prehospital Management of Acute Myocardial Infarction
Chest pain is the main symptom of acute myocardial infarction. A precocious analgesic treatment is justified by patient's comfort and unfavorable hemodynamic consequences of persistent pain.
- Trial name
- MAMI (NCT07445737)
- Testing
- Methoxyflurane, Morphine
- Where
- France
- Volunteers
- 700 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
ST Elevation Myocardial Infarction
Optimal Reperfusion Strategy for STEMI Patients With Anticipated PPCI Delay
The OPTIMAL-REPERFUSION trial will help determine whether reduced-dose facilitated PCI strategy improves clinical outcomes in patients with STEMI and anticipated PPCI delay
- Trial name
- NCT04752345
- Testing
- Pharmacoinvasive strategy, Reduced-dose facilitated PCI strategy
- Volunteers
- 632 people
- Sponsor
- West China Hospital
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