Clinical trials: ST Segment Elevation Myocardial Infarction (STEMI)
Coronary Artery Disease, Acute Myocardial Infarction
Effects of Intracoronary Progenitor Cell Therapy on Coronary Flow Reserve After Acute MI
Coronary flow reserve is an important measure of the integrity of the coronary microcirculation. Moreover, impaired coronary flow reserve is a predictor of future cardiovascular events and poor prognosis in patients after acute…
- Trial name
- REPAIR-ACS (NCT00711542)
- Testing
- autologous bone marrow-derived progenitor cells
- Where
- 2 sites in Germany
- Volunteers
- 31 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Acute Coronary Syndromes, STEMI
Early Single Antiplatelet Therapy After IVUS-Guided PCI in Acute Coronary Syndrome
This is a prospective, open-label, multicenter, randomized, phase IV clinical trial designed to evaluate the safety and efficacy of early aspirin discontinuation followed by potent P2Y12 inhibitor monotherapy after intravascular…
- Conditions
- Acute Coronary Syndromes, STEMI, NSTEMI, Unstable Angina
- Trial name
- SAPT-ACS (NCT07684742)
- Testing
- Early P2Y12 Inhibitor Monotherapy, Standard Dual Antiplatelet Therapy
- Where
- South Korea
- Volunteers
- 1,900 people
- Sponsor
- Gyeongsang National University Hospital
ST Elevation Myocardial Infarction
Reduced Stent Strategy Versus Conventional Percutaneous Coronary Revascularization in Patients Presenting With STEMI
The objective is to compare a reduced stent strategy based on drug-coated balloon (DCB) percutaneous coronary intervention (PCI) with conventional drug-eluting stent (DES) coronary revascularization in patients presenting with…
- Trial name
- COPERNICAN (NCT06353594)
- Testing
- Primary PCI
- Where
- 23 sites in Spain
- Volunteers
- 1,272 people
- Sponsor
- Hospital Universitario La Fe
Myocardial Infarction
Two- Dimensional Speckle Tracking Echocardiography After Primary Percutaneous Coronary Intervention
ST-segment elevation myocardial infarction (STEMI) is a major cause of morbidity and mortality worldwide. In spite of decrease in acute and long-term mortality following STEMI in parallel with more use of reperfusion therapy…
- Trial name
- NCT04228510
- Testing
- 2D speckle tracking echocardiography
- Volunteers
- 204 people
- Sponsor
- Assiut University
Acute Myocardial Infarction
ClearWay Rx Readmission Registry
The purpose of this registry is to determine if delivery of weight adjusted, in a large dose with either Abcixmab or Eptifibitide through the ClearWay™ RX, in patients admitted for primary coronary intervention lowers readmission…
- Trial name
- ClearWay (NCT01673893)
- Testing
- ClearWay™ Rx catheter
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Cardiovascular Institute of the South Clinical Research Corporation
Predictive Value of Admission Blood Glucose Level in Acute Myocardial Infarction
Predictive Value Of Admission Blood Glucose Level In Patients With Acute Myocardial Infarction
Coronary atherosclerosis is the leading cause of death worldwide. Diabetes mellitus is associated with increased prevalence of coronary artery disease Increased plasma glucose is a common feature in the acute phase of myocardial…
- Trial name
- NCT03164707
- Testing
- Blood Glucose Level
- Volunteers
- 100 people
- Sponsor
- Assiut University
ST Elevated Myocardial Infarction Undergoing Mechanical Reperfusion
Primary Angioplasty for STEMI During COVID-19 Pandemic (ISACS-STEMI COVID-19) Registry
The ISACS STEMI COVID-19 has been established in response to the emerging outbreak of COVID-19 to provide a European overview to estimate the real impact of COVID-19 pandemic on treatment and outcome of STEMI by primary…
- Trial name
- ISACS-STEMI (NCT04412655)
- Testing
- Percutaneous Coronary Revascularization for STEMI
- Where
- Italy
- Volunteers
- 6,609 people
- Sponsor
- Università degli Studi del Piemonte Orientale Amedeo Avogadro
ST-elevation MI, Hypothermia
Evaluation of Ultrafast Hypothermia Before Reperfusion in STEMI Patients
This study will look at the safety of treating patients with heart attack with mild hypothermia induced using a system of automated peritoneal lavage.
- Trial name
- VELOCITY (NCT01655433)
- Testing
- Velomedix APLS device, No Hypothermia Treatment
- Where
- 7 sites in United States, Canada
- Volunteers
- 54 people
- Sponsor
- Velomedix, Inc.
Myocardial Infarction, Angioplasty
Efficacy of High Dose atorvaSTATIN Loading Before Primary Percutaneous Coronary Intervention in ST Elevation Myocardial Infarction (STATIN STEMI)
Although statin prior to PCI has favorable effects in stable angina and ACS except ST elevation MI (STEMI), there have been few studies for STEMI. Celik T et al.
- Conditions
- Myocardial Infarction, Angioplasty, Percutaneous Coronary
- Trial name
- STATIN STEMI (NCT00808717)
- Testing
- Atorvastatin
- Where
- South Korea
- Volunteers
- 170 people
- Sponsor
- Yonsei University
ST Elevation Myocardial Infarction
The Eosinophils Percentage Predicts In-hospital Major Adverse Cardiac Events in STEMI Patients After PCI
Eosinophils (EOS) in peripheral blood are significantly decreased in ST-segment elevation myocardial infarction (STEMI) and the reduced EOS indicates severe myocardial damage.
- Trial name
- NCT03740776
- Volunteers
- 2 people
- Sponsor
- Dongying Zhang
Acute Non-ST Elevation Myocardial Infarction
DLBS1033 for Acute NSTEMI Without Early Coronary Revascularization
This is a prospective, randomized, double-blind, double-dummy, and controlled study of DLBS1033 in the management of acute non-ST elevation myocardial infarction (NSTEMI) without early coronary revascularization.
- Trial name
- NCT02146664
- Testing
- DLBS1033
- Where
- 2 sites in Indonesia
- Sponsor
- Dexa Medica Group
ST Elevation Acute Myocardial Infarction
COMBinAtion Therapy in Myocardial Infarction: The COMBAT-MI Trial
Remote ischemic conditioning (RIC) and intravenous exenatide administered immediately before primary angioplasty have been found to limit infarct size in patients with STEMI (ST segment elevation myocardial infarction), but the…
- Trial name
- COMBAT-MI (NCT02404376)
- Testing
- Exenatide, Remote Ischemic Conditioning (RIC)
- Where
- 6 sites in Spain
- Volunteers
- 378 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Clonal Hematopoiesis, Clonal Hematopoiesis of Indeterminate Potential
CHIP in Health and Disease
Clonal hematopoiesis (CH), including clonal hematopoiesis of indeterminate potential (CHIP), is an age-associated condition characterized by the expansion of hematopoietic stem and progenitor cell clones carrying acquired somatic…
- Conditions
- Clonal Hematopoiesis, Clonal Hematopoiesis of Indeterminate Potential, Clonal Cytopenia of Undetermined Significance (CCUS), Myelodysplastic Syndrome
- Trial name
- CHIP2 (NCT07780552)
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- VASCage GmbH
ASCVD, NSTEMI
Telehealth Group Counseling and Preventive Care for Women
The purpose of this study is to utilize an innovative healthcare delivery strategy via telehealth group counseling sessions to improve engagement, adherence, and ultimately outcomes in female patients with atherosclerotic…
- Conditions
- ASCVD, NSTEMI, STEMI, Coronary Artery Disease
- Trial name
- NCT06404515
- Testing
- Telehealth Group Counseling
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Weill Medical College of Cornell University
NSTEMI, NSTE-ACS (NSTEMI and UA)
Prognostic Impact of Guideline-recommended Timing for Invasive Strategy in NSTEMI
The objective of this multicentric observational study is to evaluate the prognostic influence of adherence or non-adherence to the recommended coronary angiography timeframe (within 24 hours) and the six-month prognosis of the…
- Conditions
- NSTEMI, NSTE-ACS (NSTEMI and UA), NSTEMI - Non-ST-Segment Elevation Myocardial Infarction
- Trial name
- NCT07204847
- Where
- France
- Volunteers
- 407 people
- Sponsor
- University Hospital, Montpellier
Coronary Artery Stenoses, Stable Angina
e-BioMatrix 6 Month DAPT France
Prospective, multi-center observational study to be conducted in up to 30 French interventional cardiology centers. The purpose of this observational study is to capture, in French Centers, clinical data of the BioMatrix Flex™…
- Conditions
- Coronary Artery Stenoses, Stable Angina, Ischemia, NSTEMI - Non-ST Segment Elevation MI
- Trial name
- NCT03461484
- Volunteers
- 2,098 people
- Sponsor
- Biosensors Europe SA
ST Elevation Myocardial Infarction (STEMI)
Effect of Long Term Trimetazidine Treatment on Final Myocardial Fibrosis for ST Eleviation Myocardial Infarction
Trimetazidine is a agent promoting glucose utilization by limiting fatty-acid oxidation.Trimetazidine could improve cardiac function in patients with ischemic heart disease.
- Trial name
- Easy (NCT07325955)
- Where
- China
- Volunteers
- 194 people
- Sponsor
- Chinese PLA General Hospital
ST Elevation Myocardial Infarction
The Incidence, Effect and Persistence of Fragmented-QRS, in Patients Presenting With ST-Elevation Myocardial Infarction
This study will assess the incidence, effect and persistence of F-QRS (Fragmented-QRS) in STEMI (ST-elevation Myocardial Infarction) patients post-PCI (percutaneous coronary intervention).
- Trial name
- NCT03156699
- Where
- United Kingdom
- Volunteers
- 64 people
- Sponsor
- The Royal Wolverhampton Hospitals NHS Trust
Acute Coronary Syndrome
Vaccination Against Influenza to Prevent Cardiovascular Events After Acute Coronary Syndromes
Cardiovascular disease has a great burden in the context of public health, as well as the low pharmacological adherence of patients who have chronic non-transmissible diseases.
- Trial name
- VIP-ACS (NCT04001504)
- Testing
- Double Dose Quadrivalent Influenza Vaccine, Standard Dose Quadrivalent Influenza Vaccine
- Where
- 22 sites in Brazil
- Volunteers
- 1,801 people
- Sponsor
- Hospital Israelita Albert Einstein
ST-segment Elevation Myocardial Infarction
Efficacy and Safety Study of Deferred Stenting in Patients With STEMI
It is known that no reflow phenomenon by microvascular obstruction after revascularization in STEMI increase infarct size, cardiac remodeling, and a risk of late mortality.
- Trial name
- INNOVATION (NCT02324348)
- Testing
- Deferred coronary stenting, Immediate coronary stenting
- Where
- South Korea
- Volunteers
- 114 people
- Sponsor
- Korea University Anam Hospital
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