Clinical trials: ST Segment Elevation Myocardial Infarction (STEMI)
ST Elevation Myocardial Infarction
Trial Comparing Radial and Femoral Approach in Primary Percutaneous Coronary Intervention (PCI)
Percutaneous coronary interventions (PCIs) from the femoral approach have more bleeding complications related to access site in comparison to the radial approach in patients with acute coronary syndrome (ACS).
- Trial name
- STEMI-RADIAL (NCT01136187)
- Testing
- Access site in primary PCI
- Where
- 4 sites in Czechia
- Volunteers
- 707 people
- Sponsor
- Charles University, Czech Republic
ST Segment Elevation Myocardial Infarction
NBS10 (Also Known as AMR-001) Versus Placebo Post ST Segment Elevation Myocardial Infarction
This study will assess the safety and efficacy of intracoronary artery administered autologous bone marrow derived stem cells in subjects post ST segment elevation myocardial infarction (STEMI).
- Trial name
- PreSERVE-AMI (NCT01495364)
- Testing
- NBS10
- Where
- 58 sites in United States
- Volunteers
- 195 people
- Sponsor
- Lisata Therapeutics, Inc.
ST Elevation Myocardial Infarction
Remote Ischemic Conditioning in ST-elevation Myocardial Infarction as Adjuvant to Primary Angioplasty
The primary objective of the RIC-STEMI trial is to assess whether remote ischaemic conditioning (RIC) as an adjunctive therapy during primary percutaneous coronary intervention (PCI) in patients presenting with ST-elevation…
- Trial name
- RIC-STEMI (NCT02313961)
- Testing
- Remote ischaemic conditioning
- Where
- Portugal
- Volunteers
- 516 people
- Sponsor
- Hospital de Braga
ST-segment Elevation Myocardial Infarction
Henan STEMI Registry
ST-segment elevation myocardial infarction (STEMI) remains among the most acute and critical diseases, with primary percutaneous coronary intervention (pPCI) and thrombolysis as mainstay reperfusion treatments.
- Trial name
- NCT02641262
- Where
- China
- Volunteers
- 5,479 people
- Sponsor
- Henan Institute of Cardiovascular Epidemiology
Out-Of-Hospital Cardiac Arrest, Infarction, Myocardial
Post-ROSC Electrocardiogram After Cardiac arrEst
PEACE study retrospectively evaluate patients who suffered an out-hospital cardiac arrest (OHCA) and who underwent a coronary angiography, enrolled in the registry of the Province of Pavia (Italy), Ticino Region (Switzerland)…
- Trial name
- PEACE (NCT04096079)
- Volunteers
- 1,000 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
STEMI, NSTEMI
Assessment of Individual Risk of Cardiovascular Events by Platelet FcGammaRIIa
This is a Prospective, Observational Multicenter Non-Interventional Cohort Study. The primary objective is to determine whether platelet expression of FcγRIIa is associated with risk of myocardial infarction (MI), stroke and…
- Trial name
- NCT05175261
- Testing
- Prolocor pFCG test
- Where
- United States
- Volunteers
- 764 people
- Sponsor
- Prolocor, Inc
Tomography, Optical Coherence, Myocardial Revascularization
The FAST OCT Study
This trial is designed to associate angiography-based fractional flow reserve (3D-angio-based FFR) values with optical coherence tomography findings in pre- and post-percutaneous coronary intervention in patients with non-ST…
- Conditions
- Tomography, Optical Coherence, Myocardial Revascularization, NSTEMI - Non-ST Segment Elevation MI, Unstable Angina
- Trial name
- NCT04683133
- Testing
- Optical coherence tomography assessment
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Erasmus Medical Center
NSTEMI - Non-ST Segment Elevation MI, STEMI (ST Elevation MI)
Aspirin-free Strategy With Ticagrelor in Patients With a Myocardial Infarction Treated Medically Alone
In patients with a myocardial infarction (MI) treated medically alone, the objective of the PANTHEON trial is to evaluate if ticagrelor monotherapy reduces bleeding events, without an increase in patient-oriented ischemic events…
- Conditions
- NSTEMI - Non-ST Segment Elevation MI, STEMI (ST Elevation MI), Myocardial Infarction
- Trial name
- PANTHEON (NCT07257198)
- Testing
- Ticagrelor + aspirin
- Where
- Canada
- Volunteers
- 2,570 people
- Sponsor
- Montreal Heart Institute
Myocardial Infarction
Utility of Residual Syntax Score to Predict Outcome After Acute Myocardial Infarction
The aim of this study is to evaluate the utility of residual syntax score after PCI of the culprit vessel for patients with AMI (STEMI or NSTEMI) to predict 6-months clinical outcomes.
- Trial name
- NCT05392777
- Testing
- Residual syntax score
- Where
- Egypt
- Volunteers
- 490 people
- Sponsor
- Cairo University
STEMI - ST-segment Elevation Myocardial Infarction, Chest Pain
SMARTwatch for the Diagnosis of ST-segment Elevation Myocardial Infarction in Patients With Chest Pain
The main symptom that initiates the diagnostic and therapeutic process for patients with suspected acute coronary syndrome is chest pain.
- Trial name
- SMART-CART-AMI (NCT07780942)
- Testing
- ECG smartwatch recording
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Hospital General Universitario Santa Lucia
ST Elevation Myocardial Infarction
Evolocumab in STEMI
The goal of this clinical trial is to compare the size of myocardial infarct between evolocumab and control groups in patients with ST segment elevation myocardial infarction who undergoing primary percutaneous coronary…
- Trial name
- EVO-STEMI (NCT06081803)
- Testing
- Repatha®
- Where
- South Korea
- Volunteers
- 166 people
- Sponsor
- Sejong General Hospital
Ischemic Heart Disease (IHD)
XTR003 PET Radiotracer for the Detection of Viable Myocardium
The study was designed to explore the clinical feasibility of XTR003, a PET myocardial fatty-acid tracer, for the detection of viable myocardium in patients with ischemic heart disease (IHD).
- Trial name
- NCT05885854
- Testing
- XTR003
- Where
- China
- Volunteers
- 51 people
- Sponsor
- Sinotau Pharmaceutical Group
Myocardial Infarction
Optimizing Infarct Size by Transforming Emergent Stenting Into an Elective Procedure Study
The goal of primary PCI is to restore anterograde myocardial flow. Stenting a largely thrombotic lesion may determine distal embolisation of thrombotic material therefore deteriorating myocardial perfusion.
- Trial name
- OPTIMASTRATEGY (NCT01462188)
- Testing
- Immediate stenting, Delayed stenting
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Marco Valgimigli
Myocardial Infarction
Reappraisal of GIK in Acute STEMI by Pre-hospital Administration
The purpose of this study is: 1. to assess whether pre-hospital glucose-insulin-potassium (GIK) administration in acute STEMI patients would reduce infarct size and ischemia/reperfusion damage using comprehensive tissue…
- Trial name
- REAGIK-STEMI (NCT02591927)
- Testing
- Glucose-Insulin-Potassium, Glucose 5%
- Where
- Switzerland
- Volunteers
- 334 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
ST Elevation Myocardial Infarction (STEMI), Acute Coronary Syndromes (ACS)
A Single-Center, Retrospective, Propensity-Score-Matched Cohort Study Comparing Drug-Coated Balloon Versus Drug-Eluting Stent for Reducing Immediate Post-Procedural Slow-Flow/No-Reflow in Acute ST-Elevation Myocardial Infarction Patients With High Thrombus Burden
This is a single-center, retrospective, propensity-score-matched observational study. It aims to compare the rate of immediate slow-flow or no-reflow after percutaneous coronary intervention (PCI) between drug-coated balloon…
- Trial name
- STEMI-DCB (NCT07806370)
- Testing
- Drug-Coated Balloon (DCB), Drug-Eluting Stent (DES)
- Where
- China
- Volunteers
- 668 people
- Sponsor
- Xijing Hospital
Acute Coronary Syndrome, Unstable Angina
Acute Coronary Syndrome Sri Lanka Audit Project
ACSSLAP is the first island wide audit project in Sri Lanka on ACS.
- Conditions
- Acute Coronary Syndrome, Unstable Angina, Non ST Elevation Myocardial Infarction, ST Elevation Myocardial Infarction
- Trial name
- ACSSLAP (NCT02893280)
- Testing
- aspirin, clopidogrel, statin, enoxaparin, streptokinase
- Where
- Sri Lanka
- Sponsor
- University of Colombo
Acute Myocardial Infarction
Mortality Analysis of ST Elevation Myocardial Infarction (STEMI) Patients in Belgium
The purpose of this observational study is to assess predictors of in-hospital mortality in patients with acute myocardial infarction admitted to Belgian hospitals.
- Trial name
- NCT00727623
- Where
- Belgium
- Volunteers
- 20,000 people
- Sponsor
- Universiteit Antwerpen
STEMI - ST Elevation Myocardial Infarction
Effects of Salvianolate Injection on Myocardial Microcirculation in Patients With Acute STEMI After Primary PCI
To evaluate the influence of Salvianolate injection on myocardial microcirculation perfusion in subjects with STEMI who underwent primary PCI
- Trial name
- SISTEMI (NCT03045562)
- Testing
- Normal saline, Salvianolate injection
- Where
- China
- Volunteers
- 536 people
- Sponsor
- Green Valley Group of China
STEMI
Effects of PCSK-9 Inhibitor Treatment Prior to Undergoing Primary Percutaneous Coronary Intervention in Patients With ST-segment Elevation Myocardial Infarction
Acute ST-segment elevation myocardial infarction (STEMI) is a common manifestation of cardiovascular emergencies. Percutaneous coronary intervention (PCI) and guideline-recommended pharmacotherapy have reduced mortality rates…
- Trial name
- NCT06364124
- Testing
- evolocumab, standard post-treatment for STEMI
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Beijing Luhe Hospital
Myocardial Infarction, Coronary Artery Disease
Safety and Efficacy Study of CYPHER® Sirolimus Stent and ENDEAVOR® Zotarolimus Stent in Patients With Acute ST Elevation Myocardial Infarction (STEMI) and Analysis of Current Status of Emergency PCI Green Channel for STEMI Patients in China
This study is to compare the clinical effect of CYPHER® stent and ENDEAVOR® stent in patients with acute ST elevation myocardial infarction.
- Trial name
- CREST-MI (NCT00781716)
- Testing
- Drug eluting coronary stent system
- Where
- China
- Volunteers
- 1,020 people
- Sponsor
- Beijing Chao Yang Hospital
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