Clinical trials: ST-elevation Myocardial Infarction (STEMI)
ST-elevation Myocardial Infarction (STEMI)
Effect of Digitally Supported Medical Nutrition Therapy on Left Ventricular Ejection Fraction in Patients With ST-Elevation Myocardial Infarction
This study is designed to investigate the effect of a nutrition program supported by digital content on heart function in patients who have experienced a heart attack with ST-elevation.
- Trial name
- NCT07427199
- Testing
- Digital Content-Supported Medical Nutrition Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Saglik Bilimleri Universitesi
STEMI - ST Elevation Myocardial Infarction
Prognostic Markers of Patients With STEMI
To analyze the relationship between the clinical data and the outcomes of STEMI patients.
- Trial name
- NCT03527940
- Where
- China
- Volunteers
- 932 people
- Sponsor
- Chongqing Medical University
Cardiac Magnetic Resonance, Extracellular Volume Overload
Extracellular Volume Associated With New-Onset Atrial Fibrillation
Left ventricular fibrosis is strongly associated with atrial fibrillation (AF). However, the relationship between LV fibrosis and new-onset AF (NOAF) after ST-segment elevation myocardial infarction (STEMI) is currently unknown.
- Conditions
- Cardiac Magnetic Resonance, Extracellular Volume Overload, Myocardial Infarction, Atrial Fibrillation
- Trial name
- NCT06447857
- Testing
- Cardiac MRI
- Where
- China
- Volunteers
- 589 people
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University
ST Elevated Myocardial Infarction
Rituximab in Patients With ST-elevation Myocardial Infarction
The main objective is to compare the effect of a single injection of two doses of rituximab versus placebo on 6 months left ventricular systolic function, using CMR, in patients who have had an acute anterior STEMI.
- Trial name
- RITA-MI2 (NCT05211401)
- Testing
- Active arm 1000 mg
- Where
- France
- Volunteers
- 372 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Vitamin D Deficiency, Non-ST Elevation Myocardial Infarction (nSTEMI)
Vitamin D Deficiency Treatment Outcomes After Non-ST-Segment Elevation Myocardial Infarction
The leading cause of death in the world is due to cardiovascular events, which originate from coronary artery stenosis therefore it affects myocardial blood flow and finally may cause infarction.
- Conditions
- Vitamin D Deficiency, Non-ST Elevation Myocardial Infarction (nSTEMI), Inflammation, Coronary Artery Disease With Myocardial Infarction
- Trial name
- NAVID (NCT03405207)
- Testing
- Vitamin D3 50000 UNT Oral Capsule
- Where
- Iran
- Volunteers
- 70 people
- Sponsor
- Isfahan University of Medical Sciences
ST-segment Elevation AMI
Efficacy of Early Intensive ROsuvastatin Therapy in Patients With ST-segment Elevation Myocardial Infarction Undergoing PrimARY Percutaneous Coronary Intervention (the ROSEMARY Trial)
Objectives: An investigator-initiated, double-blind, randomized, placebo-controlled, multi-center study to evaluate the efficacy of early intensive rosuvastatin therapy (rosuvastatin 40 mg for pre-PCI loading and 7 days post PCI…
- Trial name
- NCT01153334
- Testing
- Early intensive rosuvastatin therapy (40 mg for 7days, starting in ER prior to primary PCI)
- Where
- South Korea
- Volunteers
- 125 people
- Sponsor
- Yonsei University
Non-ST-elevation Myocardial Infarction, Multivessel Coronary Artery Disease
Complete Revascularization Versus Culprit Lesion Only PCI in NSTEMI
Prospective, randomized, controlled, multicenter, open-label trial to study whether multivessel percutaneous coronary intervention (PCI) is superior over culprit-lesion only PCI in patients with non-ST-segment elevation…
- Trial name
- CompleteNSTEMI (NCT05786131)
- Testing
- Culprit-lesion revascularization, Non-culprit-lesion revascularization
- Where
- 58 sites in Austria, Germany
- Volunteers
- 3,390 people
- Sponsor
- Leipzig Heart Science gGmbH
Acute Myocardial Infarction
Efficacy of Combination of IntraCoronary Bolus Abciximab and Aspiration Thrombectomy in STEMI
The routine use of glycoprotein (Gp) IIb-IIIa inhibitor such as abciximab is not recommended by current ACC/AHA guideline (Class IIb, level of evidence of A). This may be partly due to potential increase of bleeding.
- Trial name
- ICAT (NCT01404507)
- Testing
- Gp 2b 3a inhibitor, aspiration thrombectomy, Both use
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Yonsei University
ST Elevation Myocardial Infarction
Study of Roxadustat in the Treatment of Acute Myocardial Infarction
Depite successful primary percutaneous coronary intervention (PCI) and standardized medical treatment, prognosis of acute ST-elevation myocardial infarction patents are still a poor, with high morality and various complications…
- Trial name
- ROXAMI (NCT04803864)
- Testing
- Roxadustat
- Where
- China
- Volunteers
- 158 people
- Sponsor
- Ruijin Hospital
Myocardial Infarction
Improving Door-to-Balloon Time in STEMI
The investigators prospectively determined the impact on median door-to-balloon time of a protocol mandating (1) emergency department physician activation of the catheterization lab and (2) immediate transfer of the patient to an…
- Trial name
- EHART (NCT00800163)
- Testing
- ED Activation/Immediate Transfer
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- St. Francis Hospitals & Health Centers
ST-elevation Myocardial Infarction
Prognostic Value of Copeptin for Infarct Size and Prognosis in Patients With ST-elevation Myocardial Infarction
ST-elevation myocardial infarction (STEMI) has a serious health threaten to population. PCI, which can timely restore the blood flow to the ischemic myocardium, is a well-proved measure in STEMI management.
- Trial name
- GOODI (NCT03074214)
- Testing
- percutaneous coronary intervention
- Where
- China
- Volunteers
- 275 people
- Sponsor
- Shengjing Hospital
Reperfusion Injury, Myocardial, Myocardial Infarction
Effect of L-Carnitine on Biomarkers of Myocardial Reperfusion Injury in Patients With STEMI
The study aims is to evaluate the efficacy and tolerability of L-Carnitine on biomarkers of myocardial reperfusion injury in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary PCI by the…
- Trial name
- NCT06564909
- Testing
- L-Carnitine, The standard care for the management of myocardial infarction post PCI
- Where
- Egypt
- Volunteers
- 76 people
- Sponsor
- Ain Shams University
ST Segment Elevation Myocardial Infarction, Heart Failure
Doxycycline to Protect Heart Muscle After Heart Attacks
Current medical treatment allows more people to survive heart attacks than in the past. However, some of the survivors suffer heart disease and require hospitalization later on.
- Trial name
- NCT03508232
- Testing
- Doxycycline Hyclate
- Where
- Canada
- Volunteers
- 174 people
- Sponsor
- University of Alberta
STEMI, Intravascular Imaging
Intravascular ULTRAsound-Guided PCI in Patients With ST-Elevation Myocardial Infarction
The main goal of the ULTRA-STEMI trial is to investigate the prognostic impact of IVUS-guided PCI in patients with STEMI and correlate IVUS measurements with clinical, procedural, imaging and follow-up outcomes of interest.
- Conditions
- STEMI, Intravascular Imaging, IVUS
- Trial name
- ULTRA-STEMI (NCT05974930)
- Testing
- IVUS imaging for primary PCI guidance
- Volunteers
- 80 people
- Sponsor
- Aristotle University Of Thessaloniki
Ischemic Cardiovascular Disease, Magnetic Resonance
Tissue Characterization in STEMI Using Cardiac MRI: a Multicenter Registry
This multicenter registry includes patients with a first ST-segment elevation myocardial infarction (STEMI) who underwent cardiac magnetic resonance (CMR) imaging during the acute phase and follow-up.
- Trial name
- NCT07291999
- Where
- 3 sites in Spain
- Volunteers
- 500 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Myocardial Infarction, Acute ST-Segment Elevation
Enoxaparin and Thrombolysis Reperfusion for Acute Myocardial Infarction Treatment Thrombolysis in Myocardial Infarction - Study 25 (ExTRACT-TIMI25)
The primary objective of the study is to determine whether enoxaparin compared to unfractionated heparin will reduce the composite endpoint of all-cause mortality and non-fatal myocardial re-infarction within 30 days after…
- Trial name
- NCT00077792
- Testing
- Enoxaparin sodium (XRP4563)
- Where
- 48 sites in United States, Argentina and 46 more
- Volunteers
- 20,506 people
- Sponsor
- Sanofi
ST Elevation Myocardial Infarction, Multivessel Coronary Artery Disease
Validation of vFFR as Compared to FFR to Guide Revascularization of Non-culprit Lesions in STEMI Patients
This prospective multicenter observational cohort study is designed to study the diagnostic performance of acute-setting angiography-based FFR (e.g.
- Conditions
- ST Elevation Myocardial Infarction, Multivessel Coronary Artery Disease, Percutaneous Coronary Intervention
- Trial name
- NCT05698719
- Where
- 2 sites in Netherlands, Poland
- Volunteers
- 111 people
- Sponsor
- Erasmus Medical Center
Left Ventricular Remodeling, Plasma Multi-Omics
Prediction of LVAR and MACE in STEMI Though Plasma Multiomics Analysis
To identify plasma multi-omics biomarkers that predict left ventricular adverse remodeling (LVAR) and major adverse cardiovascular events (MACE) in patients with acute ST-segment elevation myocardial infarction, and to…
- Conditions
- Left Ventricular Remodeling, Plasma Multi-Omics, Acute ST-segment Elevation Myocardial Infarction, Immunomics
- Trial name
- NCT06885619
- Testing
- Diagnostic Test: echocardiography and blood collection
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Beijing Anzhen Hospital
STEMI - ST Elevation Myocardial Infarction
Emergency Medical Services (EMS) Telehealth to Speed STEMI Reperfusion
The aim of this study is to evaluate the impact of a Telehealth program on the time from First Medical Contact (FMC) to Reperfusion in STEMI (ST-elevation myocardial infarction) patients, by supporting local paramedics in their…
- Trial name
- THOR (NCT06945900)
- Testing
- Telehealth
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Wake Forest University Health Sciences
Unstable Angina, Non-ST-Elevation Myocardial Infarction
Diagnosis and Treatment of Acute Coronary Syndrome in the ED & the Impact of Rapid Bedside cTnl on Outcome.
The primary outcome in this study will be time to discharge for low-risk patients and therapeutic turnaround time for patients with NSTEMI or unstable angina.
- Trial name
- NCT00276432
- Testing
- iSTAT point of care analyzer
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Mayo Clinic
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