Clinical trials: STEMI (ST Elevation MI)
ST Elevation Myocardial Infarction
Risk Characterization of Non-culprit Vessels in Patients Undergoing Primary PCI for ST-elevation MI in Multivessel Disease
Most heart attacks occur because a clot forms in a coronary artery blocking blood flow. Without blood heart muscle dies. Untreated, clots can cause a specific type of heart attack -ST-elevation myocardial infarction (STEMI).
- Trial name
- PICNIC (NCT06506448)
- Testing
- CT Coronary Angiography
- Where
- 3 sites in United Kingdom
- Volunteers
- 320 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Myocardial Infarction
Chronic Remote Ischemic Conditioning to Modify Post-MI Remodeling
During a heart attack, an artery carrying blood and oxygen to the heart becomes blocked, which causes damage to the heart muscle.
- Trial name
- CRIC-RCT (NCT01817114)
- Testing
- Auto Remote Ischemic Conditioning (AutoRIC) device
- Where
- 3 sites in Canada
- Volunteers
- 20 people
- Sponsor
- The Hospital for Sick Children
STEMI (ST Elevation MI)
Randomised EValuation of Therapies for microvAscuLar Injury in STEACS
The goal of this interventional study is to evaluate if the CoFI system can act as a platform for intracoronary infusion of therapeutic agents to treat and relieve microvascular injury in ST Elevation Acute Coronary Syndrome…
- Trial name
- REVITALISE (NCT06935383)
- Testing
- Therapeutic sequence, Diagnostic sequence
- Volunteers
- 250 people
- Sponsor
- CorFlow Therapeutics AG
Familial Hypercholesterolemia, Familial Hypercholesterolemia Due to Genetic Defect of Apolipoprotein B
Advancing Cardiac Care Unit-based Rapid Assessment and Treatment of hypErcholesterolemia
ACCURATE will test the hypothesis that opportunistic genetic testing for Familial Hypercholesterolemia (FH) in patients admitted to hospital with an acute coronary syndrome will increase the diagnosis of FH and will impact…
- Conditions
- Familial Hypercholesterolemia, Familial Hypercholesterolemia Due to Genetic Defect of Apolipoprotein B, Familial Hypercholesterolemia Due to Heterozygous LDL Receptor Mutation, Familial Hypercholesterolemia - Heterozygous
- Trial name
- ACCURATE (NCT05218005)
- Testing
- Research-based genetic test for Familial Hypercholesterolemia
- Where
- 2 sites in Canada
- Volunteers
- 140 people
- Sponsor
- University of British Columbia
Thrombosis, Atherothrombosis
In-vivo Thrombus Imaging With 18F-GP1, a Novel Platelet PET Radiotracer
To date, the investigators have successfully employed a radiotracer (18F-sodium fluoride) as a marker of necrotic inflammation in human atherosclerosis.
- Conditions
- Thrombosis, Atherothrombosis, Myocardial Infarction, STEMI
- Trial name
- iThrombus (NCT03943966)
- Testing
- 18F-GP1 PET CT
- Where
- United Kingdom
- Volunteers
- 73 people
- Sponsor
- University of Edinburgh
Myocardial Infarction
Invasive vs. Conservative Management in Cancer Patients With Non-ST Elevation MI (CAN-NSTEMI)"
This retrospective study investigates the impact of invasive versus conservative management strategies in cancer patients presenting with non-ST elevation myocardial infarction (non-ST MI).
- Trial name
- CAN-NSTEMI (NCT06702436)
- Testing
- Observational Study
- Where
- Turkey (Türkiye)
- Volunteers
- 12,500 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
ACS - Acute Coronary Syndrome, NSTEMI - Non-ST Segment Elevation MI
MCG Discovery Study in Emergency Departments
This prospective discovery study is designed to demonstrate the feasibility of using an unshielded, mobile MCG device in an Emergency Department (ED) setting.
- Trial name
- NCT06095557
- Testing
- Sponsor MCG device
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- SB Technology, Inc.
STEMI
Randomized Placebo-controlled Trial of Inhaled iNO in Acute ST-segment Elevation MI Treated by Primary Angioplasty
Reperfusion of ischemic myocardium, termed ischemia/reperfusion during the treatment of MI may result in paradoxical myocardial injury compromising myocardial salvage and left ventricular functional recovery.
- Trial name
- ENAMOR (NCT00854711)
- Testing
- inhaled nitric oxide
- Where
- Israel
- Volunteers
- 7 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Anterior MI
Impact of DApagliflozin on Cardiac Function Following Anterior Myocardial Infarction in Non-Diabetic Patients
Sodium glucose co-transporter 2 inhibitors (SGLT2i) proved their favorable outcomes in heart failure. However, it is still unknown if their role extent into preventing heart failure, especially after acute myocardial infarction.
- Trial name
- DACAMI (NCT05424315)
- Testing
- Dapagliflozin 10mg, Glucose Tab
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Omar Younis