Clinical trials: Sacroiliitis
Sacroiliac Joint Disruption, Degenerative Sacroiliitis
Post-Market Feasibility Study of the Tenon Medical CATAMARAN™ SI Joint Fusion System
The purpose of this study is to evaluate the outcomes of patients with sacroiliac joint pain treated with the CATAMARAN SI Joint Fusion System.
- Trial name
- NCT05633888
- Testing
- CATAMARAN SI Joint Fusion System
- Where
- 6 sites in United States
- Volunteers
- 50 people
- Sponsor
- Tenon Medical
Degenerative Sacroiliitis, Sacroiliac Joint Disruption
Investigation of Sacroiliac Fusion Treatment (INSITE)
The purpose of this study is to compare outcomes when patients with degenerative sacroiliitis (arthritis of the SI joint) and or sacroiliac disruption (abnormal separation or tearing of the sacroiliac joint)undergo either SI…
- Trial name
- INSITE (NCT01681004)
- Testing
- iFuse Implant System, Non-surgical management
- Where
- 19 sites in United States
- Volunteers
- 159 people
- Sponsor
- SI-BONE, Inc.
Enthesitis Related Arthritis (ERA)
A Study of the Efficacy and Safety of Adalimumab in Pediatric Subjects With Enthesitis Related Arthritis
The purpose of this study is to evaluate the efficacy and safety of adalimumab given subcutaneously every other week (eow) as compared to placebo in pediatric subjects with Enthesitis Related Arthritis (ERA).
- Trial name
- NCT01166282
- Testing
- adalimumab
- Volunteers
- 46 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Sacroiliac Dysfunction
Study of Bone Growth in the Sacroiliac Joint After Minimally Invasive Surgery With Titanium Implants
SALLY studies sacroiliac joint fusion with the iFuse-3D implant.
- Trial name
- SALLY (NCT03122899)
- Testing
- SIJ fusion with iFuse-3D
- Where
- 11 sites in United States
- Volunteers
- 51 people
- Sponsor
- SI-BONE, Inc.
Sacroiliitis
CT Follow-Up of the SImmetry Sacroiliac Joint Fusion System
This study will evaluate long-term follow-up of subjects implanted with the SImmetry Sacroiliac (SI) Joint Fusion System (SImmetry).
- Trial name
- NCT02425631
- Testing
- SImmetry Sacroiliac Joint Fusion System
- Volunteers
- 19 people
- Sponsor
- Zyga Technology, Inc.
Sacroiliac Joint Disruption, Degenerative Sacroiliitis
Tenon Medical CATAMARAN™ SI Joint Fusion System CT Scan Study
The objective of this study is to evaluate 6-to-12-month radiographic outcomes of patients with sacroiliac joint disruptions or degenerative sacroiliitis that have already undergone treatment with the CATAMARAN SI Joint Fusion…
- Trial name
- NCT05628142
- Testing
- Pelvic CT Scan
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Tenon Medical
SI Joint Pain
Validity and Reliability of Diagnostic Findings of SI Joint Blocking
The purpose of the trial is to confirm the validity and reliability of diagnostic SI joint blocks.
- Trial name
- VaReFi (NCT01874236)
- Testing
- 0.75% bupivacaine, .75% bupivacaine
- Where
- 7 sites in United States
- Volunteers
- 28 people
- Sponsor
- SI-BONE, Inc.
Sacroiliitis, Sacroiliac Joint Dysfunction
Clinical Outcome and Fusion Results Using the SiJoin® Transfixing Sacroiliac Fusion Device
The purpose of this clinical study is to evaluate fusion of the SI joint(s) and any reduction in VAS pain scores in a prospective cohort of patients utilizing the SiJoin® Transfixing Sacroiliac Fusion Device in patients that…
- Conditions
- Sacroiliitis, Sacroiliac Joint Dysfunction, Iatrogenic Injury, Osteitis Condensans Ilii
- Trial name
- NCT05712850
- Testing
- SiJoin® Transfixing Sacroiliac Fusion Device
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- VG Innovations, LLC
Ankylosing Spondylitis
Study to Demonstrate the Efficacy, Safety and Tolerability of an Intravenous Regimen of Secukinumab Compared to Placebo in Subjects With Active axSpA
The purpose of this global study was to demonstrate the efficacy, safety, and tolerability of an intravenous (i.v.) regimen of secukinumab compared to placebo in participants with active ankylosing spondylitis (AS) or…
- Trial name
- NCT04156620
- Testing
- Secukinumab
- Where
- 102 sites in United States, Belgium and 16 more
- Volunteers
- 527 people
- Sponsor
- Novartis Pharmaceuticals
Sacroiliitis
Use of the Neurolyser XR for the Treatment of Low Back Pain Related to Sacroiliitis
The Neurolyser XR is a device used to deliver high-intensity focused ultrasound for the ablation of the lateral sacral branch nerve in patients with Sacroiliitis.
- Trial name
- NCT06053255
- Testing
- High-intensity focused ultrasound for Sacroiliitis using the Neurolyser XR
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- FUSMobile Inc.
Sacroiliitis
Safety and Feasibility of the NeurolyserXR for Sacroiliac Joint Pain
Pilot study to evaluate the safety and the effectiveness of the Neurolyser XR as a treatment for sacroiliitis
- Trial name
- NCT05396495
- Testing
- NeurolyserXR
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- FUSMobile Inc.
Sacroiliitis, Sacroiliac Joint Dysfunction
Post-Market Clinical Study on a Modular SI Joint Fusion System
A prospective study on the use of the TransLoc 3D SI Joint Fusion System for patients with sacroiliac joint disruptions or degenerative sacroiliitis.
- Trial name
- SPARTAN (NCT05916092)
- Testing
- TransLoc 3D
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- CornerLoc
Degenerative Sacroiliitis, Sacroiliac Joint Disruption
Sacroiliac Joint Fusion With iFuse Implant System (SIFI)
The purpose of this study is to evaluate the use of the iFuse Implant System to treat degenerative sacroiliitis (arthritis of the SI joint) and sacroiliac disruption (abnormal separation or tearing of the sacroiliac joint).
- Trial name
- SIFI (NCT01640353)
- Where
- 26 sites in United States
- Volunteers
- 194 people
- Sponsor
- SI-BONE, Inc.
Degenerative Sacroilitis, Sacroiliac Joint Disruption
LOIS: Long-Term Follow-Up in INSITE/SIFI
The purpose of this study is to evaluate the long term safety and effectiveness of SI joint fusion using the iFuse Implant System in patients with degenerative sacroiliitis (DS) and/or sacroiliac joint disruptions (SD).
- Trial name
- LOIS (NCT02270203)
- Testing
- Pelvic CT at 5 years post-op
- Where
- 12 sites in United States
- Volunteers
- 103 people
- Sponsor
- SI-BONE, Inc.
Sacro Iliac Joint Pain, Sacro-iliac Joints
Posterior-Inferior Intra-articular Cortical Piercing Titanium Implant for Sacroiliac Joint Fusion: Evaluation of Safety and Effectiveness Outcomes
The purpose of this study is to evaluate outcomes in patients treated with iFuse INTRA Ti for chronic SI joint pain.
- Conditions
- Sacro Iliac Joint Pain, Sacro-iliac Joints, Sacroiliac Disorder, Sacroiliac Joint Dysfunction
- Trial name
- PIERCE (NCT07565545)
- Testing
- iFuse INTRA Ti Implant System
- Volunteers
- 120 people
- Sponsor
- SI-BONE, Inc.
Non-radiographic Axial Spondyloarthritis
A Study of Secukinumab to Evaluate Maintenance of Response in Participants With Non-radiographic Axial Spondyloarthritis Who Achieved Remission
This study will establish whether prolonged chronic dosing with secukinumab is needed in participants with Non-radiographic axial spondyloarthritis, (nr-axSpA) who have achieved remission.
- Trial name
- NCT05622708
- Testing
- Secukinumab
- Where
- 61 sites in Belgium, Brazil and 16 more
- Volunteers
- 240 people
- Sponsor
- Novartis Pharmaceuticals
Degenerative Sacroiliitis, Sacroiliac Disorder
Sacroiliac Joint Fusion Intervention For Mobility, Pain Relief, and Lasting Improvement in Functional Recovery "SIMPLIFY"
The purpose of this study is to determine the clinical efficacy of The Trellis SI Joint Fusion System in unilateral sacroiliac (SI) joint fusion surgeries.
- Trial name
- SIMPLIFY (NCT07849244)
- Testing
- TRELLIS SI Joint Fusion System
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- OrthoFundamentals, LLC