Clinical trials: Safety
Medication Errors, Medical Records Systems, Computerized
Improving Pediatric Safety and Quality With Health Care Information Technology
This study includes four projects aimed to improve the quality and safety of pediatric care through the implementation of four clinical decision support services in the electronic health record (EHR).
- Conditions
- Medication Errors, Medical Records Systems, Computerized, Patient Safety, Quality Improvement
- Trial name
- NCT00134823
- Testing
- weight based dosing decision support
- Where
- United States
- Volunteers
- 5,420 people
- Sponsor
- Massachusetts General Hospital
Drug Safety
A Study to Assess the Efficacy and Safety of Fospropofol Disodium
The aim of this study was to evaluate the pharmacodynamics, safety, and tolerability of Fospropofol disodium up to a dose producing maximal hypnotic effect as defined by electroencephalogramderived assessment (Bispectral Index…
- Trial name
- NCT01271569
- Testing
- Fospropofol disodium
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Safety
Safety and Pharmacokinetics of SNX-001 in Healthy Aged Volunteers
This is a randomised, double-blind, group-sequential, placebo-controlled, safety and pharmacokinetic study in healthy, aged volunteers. Objectives: 1.
- Trial name
- NCT01269476
- Testing
- SNX-001
- Where
- Germany
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- SeneXta Therapeutics SA
The Primary Evaluation is the Change From Baseline at End of Study for CDSS Total Scores., The Secondary Efficacy Evaluations Include: MADRS, PANSS Total Scores and Subscales and Responder Rate; CGI-S and CGI-I Scales.
Efficacy and Safety of Ziprasidone to Treat Depressive Symptoms in Patients With Schizophrenia
This study is going to determine the efficacy, tolerability and safety of ziprasidone in 120 schizophrenic patients with depressive symptoms. The study will be carried out at 2 mental centers in China.
- Conditions
- The Primary Evaluation is the Change From Baseline at End of Study for CDSS Total Scores., The Secondary Efficacy Evaluations Include: MADRS, PANSS Total Scores and Subscales and Responder Rate; CGI-S and CGI-I Scales., Safety Evaluations Include: Laboratory Test Abnormalities; BARS and SAS; Physical Examinations; Vital Signs; Electrocardiogram,Etc., Subjective Well-being Under Neuroleptics Short Form Will be Used in Our Study to Assess the Subjective Side-effects.
- Trial name
- NCT01260116
- Volunteers
- 120 people
- Sponsor
- Wuhan University
The Objectives of the Study is to Evaluate the Efficacy and Safety of Acarmet (Metformin HCl 500 mg, Plus Acarbose 50 mg Tablets) Thrice Daily Versus Acarbose 50 mg Thrice Daily Over 16 Weeks in
A Phase III Randomized, Double-blind, Parallel-group Study to Evaluate the Efficacy and Safety of Acarmet (Metformin HCl 500 mg Plus Acarbose 50 mg Tablets) Versus Acarbose Alone in Subjects With Type 2 Diabetes Mellitus
Type 2 diabetes mellitus is a chronic metabolic disorder which is caused by both insulin secretion deficiency and insulin action defect.
- Conditions
- The Objectives of the Study is to Evaluate the Efficacy and Safety of Acarmet (Metformin HCl 500 mg, Plus Acarbose 50 mg Tablets) Thrice Daily Versus Acarbose 50 mg Thrice Daily Over 16 Weeks in, Subjects With Type 2 Diabetes Mellitus.
- Trial name
- NCT01245166
- Testing
- Acarbose, Metformin/Acarbose
- Where
- Taiwan
- Volunteers
- 220 people
- Sponsor
- Lotus Pharmaceutical
Safety
A Study to Assess the Pharmacokinetics, Safety and Tolerability of CT327 in Healthy Male Volunteers
K-252a is a potent inhibitor of nerve growth factor (NGF) and therefore has the ability to inhibit keratinocyte proliferation. K-252a is strongly lipophilic and therefore passes freely into the cell membranes of keratinocytes and…
- Trial name
- NCT01243502
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Creabilis SA
Bowel Preparation, Efficacy, Tolerability, Safety
Efficacy, Safety and Tolerability of Split-dose of PEG Compared With NaP Solution for Colonoscopy Preparation: A Randomized, Controlled Trial
: In several studies comparing of sodium phosphate solutions versus PEG, both regimen had similar efficacy of bowel cleansing and sodium phosphate solutions are more acceptable to patients because patient are required to consume…
- Trial name
- SPEN (NCT01229800)
- Testing
- Polyethylene glycol, Sodium phosphate(NaP) solution
- Where
- South Korea
- Volunteers
- 207 people
- Sponsor
- Inje University
Safety and Tolerability of SENSIMED Triggerfish in Glaucoma Patients
SENSIMED Triggerfish Discomfort During IOP Monitoring
Evaluation of the wearing discomfort (safety and tolerability) involved during IOP monitoring with the SENISMED Triggerfish, a sensor embedded in a telemetric contact lens
- Trial name
- 09/02 (NCT00966108)
- Testing
- SENSIMED Triggerfish
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sensimed AG
Healthy, Safety
AZD2624 Multiple Ascending Dose Study in Japan
This multiple ascending dose study will evaluate safety and tolerability after repeated ascending doses of AZD2624
- Trial name
- JMAD (NCT00696865)
- Testing
- AZD2624
- Where
- Japan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Medication Errors, Patient Safety
Impact of Computerized Physician Order Entry on Medication Prescription Errors in the Intensive Care Unit: a Controlled Cross-Sectional Trial.
Device: computerized physician order entry. We wanted to investigate if the introduction of a computerized intensive care unit system reduced the incidence and severity of medication prescription errors (MPEs).
- Trial name
- NCT00287274
- Testing
- computerized physician order entry
- Where
- Belgium
- Volunteers
- 160 people
- Sponsor
- University Hospital, Ghent
Vasomotor Symptoms, Endometrial Safety
Study of Hot Flashes and Night Sweats in Postmenopausal Women Receiving Combination Raloxifene and Oral Estrogen
This pilot study was designed to explore the effects of combined treatment with raloxifene HCl 60 mg and oral 17 beta-estradiol 1mg/day on the number of vasomotor episodes (hot flashes plus night sweats) in postmenopausal women…
- Trial name
- NCT00332553
- Testing
- Raloxifene, medroxyprogesterone acetate, estrogen
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Safety
LabAlert: Enhancing Medication Safety Through Electronic Interventions to Improve Laboratory Monitoring
Errors and preventable adverse events associated with medication prescription and dispensing are common, and the difference between guideline recommendations and the actual frequency of laboratory monitoring is substantial.
- Trial name
- NCT00256386
- Testing
- Electronic Medical Record (EMR) to clinician's in-basket, Automated Voice Message (AVM) reminder to patient's phone, Pharmacy Team phone call-letter followup
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- Kaiser Permanente