Clinical trials: Saliva
Thirst
Effectiveness of Menthol Chewing Gum in the Management of Thirst
The objective of this study was to compare the effectiveness of menthol chewing gum compared to maintained fasting (usual care) in reducing the intensity of the surgical patient's thirst during the preoperative period.
- Trial name
- NCT03200197
- Testing
- Menthol chewing gum, Usual care (fasting)
- Volunteers
- 102 people
- Sponsor
- Universidade Estadual de Londrina
Tobacco Use Cessation
Mobile Media-Rich Interactive Guideline System (MMRIGS) Pilot Study
The goal of this research study is to learn about 2 different interactive methods that are designed to help people with HIV/AIDS stop smoking.
- Trial name
- NCT02302859
- Testing
- Nicotine Patch, Questionnaires, Pamphlet
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Dental Plaque
Effect of a Propolis Tablet on the Saliva and the Amount of Adolescent Dental Plaque Microbes
The aim of the present study was to evaluate the effect of a xylitol containing propolis tablet on the salivary pH, total microorganisms count and soluble and insoluble extracellular polysaccharide concentration of the dental…
- Trial name
- NCT03394729
- Testing
- Propolis tablet to limit dental biofilm, Xilytol tablet to limit dental biofilm
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Dry Eye Disease, Xerostomia
Sphenopalatine Ganglion Stimulation for Ocular and Oral Dryness
Dry Eye Disease (DED) is a multifactorial pathology characterized by inflammation of the lacrimal functional unit that develops in ocular surface pathology, severely affecting patients quality of life.
- Trial name
- NCT05187533
- Testing
- Osteopathic protocol of Sphenopalatine Ganglion Stimulation
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA
End Stage Renal Disease
Pilot Study of Taste Sensations in Patients With End-stage Renal Disease on Hemodialysis
Individuals on dialysis due to kidney failure have very prescriptive diets. These diets help increase dialysis effectiveness and help patients control blood levels of electrolytes including potassium and phosphate, acid-base…
- Trial name
- NCT03495271
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Purdue University
Dental Caries
Fluoride in Saliva After Use of Fluoride Toothpastes Followed by Fluoride Mouthrinses
This study will evaluate fluoride (F) bioavailability in saliva when using an over-the-counter mouthrinse of 226 ppm F, immediately after brushing with an over-the-counter toothpaste of 1,100 ppm F or a prescription toothpaste of…
- Trial name
- NCT05601154
- Testing
- Crest Cavity Protection toothpaste, Crest Cavity Protection toothpaste followed by Act Mint Fluoride Rinse, Colgate PreviDent 5000+ toothpaste
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Michigan
COVID-19, Sars-CoV2
Rapid, Onsite COVID-19 Detection
The purpose of this research study is to evaluate and improve a rapid COVID-19 test. The test is designed to identify people who are most contagious and likely to spread the virus to others.
- Trial name
- NCT04460690
- Testing
- Rapid Onsite COVID-19 Detection
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- University of Wisconsin, Madison
Tetanus
TETANUS Antibody Detection in Saliva Study
This study aims to design, develop and optimise a non-invasive, saliva sample-based point-of-care lateral flow test for use in low and middle income settings that can return a qualitative result on whether an individual has or…
- Trial name
- TETANUS (NCT07446166)
- Testing
- Point of care, saliva-based lateral flow test, Blood based immunoassay
- Where
- Rwanda
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Sars-CoV2, RT-PCR
Detection of COVID-19 in Saliva Collection
Since December 2019, the world has faced a pandemic of COVID-19, an infectious disease caused by SARS-CoV-2, a virus that emerged in China.
- Conditions
- Sars-CoV2, RT-PCR, Saliva Collection, Nasopharyngeal Sample
- Trial name
- SALICOV (NCT04386551)
- Where
- France
- Volunteers
- 501 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Mouth Diseases, Periodontal Inflammation
Evaluation of Biomarkers Levels in Gingival Crevicular Fluid, Saliva and Serum for Different Periodontal Diseases
The aim of this study is; detection of interleukin(IL)-38, IL-36 gamma(γ) , IL-17 and matrix metalloproteinase(MMP)-9 levels in gingival crevicular fluid (GCF), saliva and serum samples of periodontally healthy, gingivitis and…
- Conditions
- Mouth Diseases, Periodontal Inflammation, Periodontal Diseases
- Trial name
- NCT05435131
- Testing
- GCF obtaining, Saliva Obtaining, Serum obtaining
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Xerostomia, Halitosis
Effect of Whitening Agent With Emulsion Gel in Saliva and Halitosis
The objective of this study is to evaluate how well the study product, Crest Daily Whitening Serum, alleviates Xerostomia and perceived halitosis over 1 week of use.
- Trial name
- NCT06194123
- Testing
- Crest Daily Whitening Serum
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Tufts University
Streptococcal Infections, Saliva Altered
Efficacy of Propolis Varnish Against Oral Biofilm
This study aims to evaluate the effectiveness of a varnish containing 15% of green propolis on Streptococcus mutans in saliva and biofilm.
- Trial name
- NCT02052973
- Testing
- Propolis varnish
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Heart Failure, Thirst
Using Saliva Stimulation to Immediately Improve Heart Failure Inpatient's Thirst Sensation
The purpose of this study is to Using saliva stimulation to immediately improve heart failure inpatient's thirst sensation.
- Conditions
- Heart Failure, Thirst, Saliva
- Trial name
- NCT05325983
- Testing
- lemonade ice cubes, water ice cubes
- Where
- Taiwan
- Volunteers
- 96 people
- Sponsor
- LI-JU Chen
Dental Plaque
Antibacterial Effect of the Infusion of Green Tea Used as a Mouthwash on Saliva and Bacterial Plaque
Given that the participation of oral microorganisms in the development of the most prevalent pathologies of the oral cavity is unquestionable, efforts have been made to create agents that allow controlling these bacteria.
- Trial name
- NCT04410666
- Testing
- Green Tea mouthwash
- Where
- Paraguay
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Julieta María Méndez Romero
Mouth Diseases, Quality of Life
Prospective Studies on Oral Health and Quality of Life in Head and Neck Cancer Patients
Radiation therapy (RT) leads to a markedly reduced salivary secretion rate, which makes it difficult to eat and talk and it is a risk factor for oral disorders such as caries and mucosal infections.
- Conditions
- Mouth Diseases, Quality of Life, Secretion; Salivary Gland, Deficient
- Trial name
- NCT02870270
- Testing
- Cancer treatment
- Where
- Sweden
- Volunteers
- 33 people
- Sponsor
- Göteborg University
Gingivitis, Periodontal Disease
Rapid Point-of-Care Salivary Diagnostic for Periodontal Health
The purpose of this study is to learn if a chair-side testing device will accurately measure levels of a salivary biomarker and thus indicate if a patient has periodontal health, gingivitis or periodontal disease.
- Trial name
- NCT02403297
- Testing
- Quik Check PD
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Innovative Diagnostics Inc
Electrolyte Disturbance, Saliva Altered
Effects of Cardamom and Fennel on Salivary pH and Anti Microbial Activity
Dental caries is the most prevalent infectious disease related to oral health.. Although significant advances have been made on a global front to prevent caries, studies show its incidence is on the rise making it one of the…
- Trial name
- NCT05245019
- Testing
- cardamom, fennel
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Karachi
Cognitive Function, Cardiopulmonary Function
Commuter Air Pollution Intervention Study
Traffic related air pollution is a well-recognised and much studied contributor to smog and is linked to a number of adverse health outcomes.
- Conditions
- Cognitive Function, Cardiopulmonary Function, Saliva Stress Hormones, Air Pollution Exposure
- Trial name
- CAPI (NCT02277002)
- Testing
- Cabin Air Filtration
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Health Canada
Covid19
Antiseptic Mouth Rinses to Reduce Salivary Viral Load in COVID-19 Patients
As no curative treatment for SARS-CoV-2 is currently available, most public health measures to contain the pandemic are based on preventing the spread of the pathogen.
- Trial name
- BUCOSARS (NCT04707742)
- Testing
- Betadine© bucal 100 mg/ml, Oximen® 3%, Clorhexidine Dental PHB©
- Where
- Spain
- Volunteers
- 160 people
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Sleep Problems, Insomnia
Sleep and Blankets
Purpose The primary aim of this research project is to evaluate whether a special blanket is an effective intervention for improving sleep among young people aged 16-24 with sleep disturbances.
- Trial name
- SWAN (NCT07181577)
- Testing
- Special blanket, Different special blanket
- Where
- Denmark
- Volunteers
- 672 people
- Sponsor
- Aarhus University Hospital