Clinical trials: Saphenous Vein
Varicose Veins, Vascular Diseases
New Compression Hosiery Versus Standard Class II Compression Stockings After Endothermal Ablation
A prospective comparative randomized multicentre non-inferiority trial. The purpose of this study is to compares of a short compression hosiery (stocking without a foot, compression class 2) with standard compression class 2…
- Trial name
- COSMOS (NCT03477227)
- Testing
- Short stocking, Usual stocking
- Where
- 3 sites in Russia
- Volunteers
- 187 people
- Sponsor
- Pirogov Russian National Research Medical University
Varicose Veins, Insufficiency of Great Saphenous Vein
Clinical Trial of Endovenous 940 and 1470 Laser Ablation for Treating Great Saphenous Veins
A clinical randomized controlled trial, comparing 2 endovenous laser ablation (EVLA) techniques in patients with insufficiency of the great saphenous vein (GSV).
- Trial name
- COLA (NCT01637181)
- Testing
- Endovenous laser ablation (EVLA)
- Where
- Netherlands
- Volunteers
- 142 people
- Sponsor
- Erasmus Medical Center
Saphenous Vein Cannulation
Saphenous Vein Cannulation in Infants and Small Children
The purpose of this study is to compare the two different saphenous vein cannulation techniques; real-time ultrasound image-guided technique (Ultrasound group) vs. traditional landmark technique (Landmark group).
- Trial name
- NCT01924975
- Testing
- Saphenous vein cannulation, ultrasound with a linear transducer (L15-7io), A 22 or 24 G intravenous catheter
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Satoshi Hanada
Anatomy of the GSV for Rescue Peripheral IV Access
Great Saphenous Vein Anatomy at the Proximal Medial Thigh as a Potential Site for Rescue Venous Access
The purpose of this study is to assess the anatomy of the great saphenous vein at the level of the medial thigh in the general population in an effort to categorize this as a reliable target vessel for rescue peripheral IV access.
- Trial name
- NCT04922606
- Testing
- US ot the GSV
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Coronary Artery Disease, Stable Angina
The Effect Of Ticagrelor On Saphenous Vein Graft Patency In Patients Undergoing Coronary Artery Bypass Grafting Surgery
In the POPular CABG study we investigate if the addition of ticagrelor, a drug that inhibits blood platelets from clotting, to treatment with aspirin will reduce the rate of saphenous vein graft occlusion as assessed with…
- Conditions
- Coronary Artery Disease, Stable Angina, Acute Coronary Syndrome
- Trial name
- POPular CABG (NCT02352402)
- Testing
- Ticagrelor
- Where
- 6 sites in Netherlands
- Volunteers
- 487 people
- Sponsor
- J.M. ten Berg
Varicose Veins Leg
Flush Versus Standard Distance From Saphenofemoral Junction in Endovenous Laser Ablation of Great Saphenous Vein
Varicose veins of the great saphenous vein (GSV) are a prevalent venous disorder, with higher incidence in women. They cause swelling, pain, ulcers, eczema, and phlebitis, impacting patients' occupational performance and quality…
- Trial name
- fEVLA (NCT06913322)
- Testing
- flush endovenous laser ablation of great saphenous vein, standard endovenous laser ablation of great saphenous vein
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Kafrelsheikh University
Endothelial Function of Saphenous Vein Grafts
Investigation of Endothelium in Saphenous Vein Grafts
This is a single center prospective study of 30 patients undergoing elective heart bypass surgery (CABG) with at least two vein grafts from the leg (SVG).
- Trial name
- NCT01510821
- Testing
- Use of Maquet Vasoshield Pressure-limiting syringe on SVG, Use of non-regulated syringe on SVG
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Emory University
Varicose Veins Leg, Great Saphenous Vein Insufficiency
Calcium Dobesilate After Radiofrequency Ablation for Varicose Veins
This study evaluates whether calcium dobesilate, a venoactive drug, improves recovery after radiofrequency ablation (RFA) for varicose veins.
- Conditions
- Varicose Veins Leg, Great Saphenous Vein Insufficiency, Chronic Venous Insufficiency
- Trial name
- NCT07390097
- Testing
- calcium dobesilate
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Oguz Arslanturk
Superficial Vein Thrombosis, Endovenous Laser Ablation
Endovenous Laser Ablation in Acute Thrombophlebitis of the Varicose Great Saphenous Vein
Рrospective single-centre randomized open-label study for comparison three modes of treatment for thrombosis of varicose great saphena vein - standard medical with fondaparinux sodium for 45 days, endovenous laser ablation close…
- Trial name
- NCT05001776
- Testing
- Endovenous laser ablation, Fondaparinux Sodium
- Where
- Russia
- Volunteers
- 105 people
- Sponsor
- National Medical Research Center for Therapy and Preventive Medicine
Major Adverse Cardiovascular Events, Saphenous Vein Graft Disease
Virtual Histology Intravascular Ultrasound to Evaluate Prognostic Risks of Saphenous Vein Graft Disease Before Percutaneous Coronary Intervention.
The study is a prospective cohort study conducted in Tianjin Chest Hospital, China. Patients with saphenous vein graft disease after coronary artery bypass graft, and planning for receiving percutaneous coronary intervention…
- Conditions
- Major Adverse Cardiovascular Events, Saphenous Vein Graft Disease, Virtual Histology Intravascular Ultrasound, Percutaneous Coronary Intervention
- Trial name
- NCT03175952
- Testing
- virtual histology intravascular ultrasound
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Tianjin Chest Hospital
Coronary Artery Disease
Radial Artery Versus No-touch Saphenous Vein
This study evaluates the short-term and long-term patency of the radial artery and the No-touch vein in patients undergoing isolated on-pump/off-pump coronary artery bypass graft (CABG) surgery.
- Trial name
- NCT06014047
- Testing
- No-touch vein graft, Radial artery graft
- Where
- China
- Volunteers
- 774 people
- Sponsor
- China National Center for Cardiovascular Diseases
Coronary Artery Disease
Radial Artery Versus Saphenous Vein Patency (RSVP) Trial - 10 Year Follow-up
During coronary bypass surgery, veins are taken from the leg and applied to the heart and aorta to 'bypass' narrowings in the coronary arteries.
- Trial name
- NCT01622387
- Testing
- Coronary artery bypass (CABG) surgery using a radial arterial conduit, Coronary artery bypass surgery using a long saphenous vein conduit
- Where
- United Kingdom
- Sponsor
- Imperial College London
Limb Edema, Surgical Site Infections
Prevention of Edema After Coronary Artery Bypass Graft by Customized Pressure-guided Elastic Bandages
The study aimed to assess the efficacy of customized pressure-guided elastic bandages (CPG-EB) in preventing postoperative edema and complications in Coronary Artery Bypass Graft (CABG) patients.
- Conditions
- Limb Edema, Surgical Site Infections, Leg Swelling, Compression Bandages
- Trial name
- PEACCE (NCT06603961)
- Testing
- CPG-EB group
- Where
- 2 sites in Thailand
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Coronary Arteriosclerosis
Radial Artery Versus Saphenous Vein Patency (RSVP) Study
The purpose of this study is to determine whether the radial artery (artery in the arm) or saphenous vein (vein in the leg), when used as bypass grafts for coronary artery bypass surgery, have a greater patency rate (degree of…
- Trial name
- RSVP (NCT00139399)
- Testing
- Coronary artery bypass graft (CABG) surgery
- Where
- United Kingdom
- Volunteers
- 142 people
- Sponsor
- Imperial College London
Coronary Artery Disease
The eSVS (TM) Mesh External Saphenous Vein Support Trial
Prospective, multi-center, randomized, controlled (patients as their own control) trial on an external mesh device (eSVS™, Kips Bay Medical) supporting saphenous vein grafts for coronary bypass graft surgery in patients with…
- Trial name
- eSVS (NCT00777777)
- Testing
- eSVS, saphenous vein supporting mesh
- Where
- Singapore
- Volunteers
- 120 people
- Sponsor
- National University Hospital, Singapore
Arteritis, Diabetes
Comparison of Two Lower Limb Bypass Types : Prosthesis Versus Autologous Vein
When medical treatments fail, critical ischemia of the lower limb often leads to surgery, i.e. above knee femoro popliteal bypass.
- Trial name
- REVA (NCT00221715)
- Testing
- femoropopliteal artery bypass
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Bordeaux
Postoperative Complications, Surgical Wound Infection
Acupuncture and Post-Surgical Wound Healing
The purpose of this study is to determine if acupuncture improves wound healing. Since we, the investigators at the University of California, San Francisco (UCSF), know that how much oxygen is delivered to tissue is the best…
- Conditions
- Postoperative Complications, Surgical Wound Infection, Surgical Wound Dehiscence
- Trial name
- NCT00260494
- Testing
- acupuncture
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of California, San Francisco
Varicose Veins
Prospective Randomized Trial Comparing the New Endovenous Procedures Versus Conventional Surgery for Varicose Veins Due to Great Saphenous Vein Incompetence
Through a prospective RCT evaluate and compare the three new endovenous methods for great saphenous vein ablation (Radiofrequency, endovenous laser and foam sclerotherapy) versus high ligation and stripping.
- Trial name
- RAFPELS (NCT00621062)
- Testing
- High Ligation of the GSV, Endovenous Laser Ablation, Radiofrequency ablation
- Where
- Sweden
- Volunteers
- 540 people
- Sponsor
- Uppsala University
Venous Insufficiency, Varicose Veins
Endovenous Laser Therapy (EVLT) for Sapheno-Popliteal Incompetence and Short Saphenous Vein (SSV) Reflux: A RCT
Varicose veins are a common problem, affecting up to a third of the western adult population. Most suffer with aching, discomfort, pruritis, and muscle cramps, whilst complications include oedema, eczema, lipodermatosclerosis…
- Trial name
- NCT00841178
- Testing
- Surgery, EVLT
- Where
- United Kingdom
- Volunteers
- 106 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Venous Reflux
ClosureFAST vs. Laser Ablation for the Treatment of GSV Disease: A Multicenter, Single-Blinded, Randomized Study.
The objective of this post-market study is to compare the post-procedure recovery between two types of minimally invasive catheter treatments for venous disease in the Great Saphenous Vein.
- Trial name
- RECOVERY (NCT00509392)
- Testing
- Seg. RF Ablation & ClosureFAST catheter, Endovenous Laser
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Medtronic Endovascular