Clinical trials: Saphenous Vein
Coronary Artery Disease, Myocardial Ischemia
The eSVS® Mesh Post-Marketing Trial
The purpose of this study is to evaluate patency rates of the eSVS Mesh Saphenous Vein Graph (SVG) and control SVG at six and twenty-four months via coronary angiography and analyses of Duplex Sonography Results and coronary…
- Conditions
- Coronary Artery Disease, Myocardial Ischemia, Coronary Disease, Heart Diseases
- Trial name
- NCT01520311
- Testing
- eSVS Mesh
- Where
- Switzerland
- Volunteers
- 8 people
- Sponsor
- Kips Bay Medical, Inc.
Stenosis in Saphenous Vein Graft, Drug Eluting Stent
Comparison of Safety and Efficacy of Two Different Drug Eluting Stents Implanted Into Saphenous Vein Grafts
Drug eluting stents significantly reduced the rate of in-stent restenosis in coronary arteries. There are several kinds of DES i.e. eluting the drug either from stable or biodegradable polymer.
- Trial name
- NCT00766129
- Testing
- Taxus stent implantation, Luc-Chopin stent
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- National Institute of Cardiology, Warsaw, Poland
Coronary Artery Disease, Coronary Artery Bypass Grafting
Ticagrelor-based De-escalation of Dual Antiplatelet Therapy After Coronary Artery Bypass Grafting
Ticagrelor-based De-escalation of Dual Antiplatelet Therapy After Coronary Artery Bypass Grafting trial (TOP-CABG trial) is a multicenter, randomized, double-blind, non-inferiority, parallel controlled trial.
- Conditions
- Coronary Artery Disease, Coronary Artery Bypass Grafting, Dual Antiplatelet Therapy, Bleeding
- Trial name
- TOP-CABG (NCT05380063)
- Testing
- De-escalated Dual Antiplatelet Therapy, Dual Antiplatelet Therapy
- Where
- China
- Volunteers
- 2,300 people
- Sponsor
- China National Center for Cardiovascular Diseases
Chronic Venous Insufficiency, CVI
Clinical Study to Assess the Safety and Efficacy of Mechanochemical Ablation With Flebogrif in Patients With Great Saphenous Vein Insufficiency
The objective of the study is to collect clinical data of patients in whom Flebogrif® will have been used for mechanochemical ablation of incompetent veins in the follow-up period, as related to the safety, clinical…
- Trial name
- POLFLEB (NCT04558957)
- Testing
- FLEBOGRIF
- Where
- 4 sites in Poland
- Volunteers
- 200 people
- Sponsor
- Balton Sp.zo.o.
Coronary Artery Disease
CT-angiographic Follow up of Patients That Underwent Coronary Bypass Surgery Between 1993-1997
Coronary artery surgery (CABG) is necessary to improve blood circulation in many patients with coronary artery disease. This is done by using alternative blood vessels (grafts) to bypass the stenosed coronary arteries.
- Trial name
- NCT01686100
- Testing
- No touch technique, Conventional technique
- Where
- Sweden
- Volunteers
- 52 people
- Sponsor
- Örebro County Council
Arteritis
Comparison of Two Under Knee Lower Limb Bypass Types:Endothelialised Prosthesis Versus Autologous Vein Graft
The aim of this project is to improve the hemocompatibility of vascular prosthesis with a complete covering of its endoluminal surface with autologous endothelial cells.
- Trial name
- NCT00221806
- Testing
- endothelialised prosthesis
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Bordeaux
Varicose Ulcer, Varicose Veins of Lower Limb
Venous Ulcer: Endovenous Radiofrequency Treatment Trial
The aim of this study is to analyze the effect of intravenous therapy with radiofrequency for superficial and perforating venous insufficiency versus compression therapy with multilayer banding in patients with active venous…
- Conditions
- Varicose Ulcer, Varicose Veins of Lower Limb, Saphenous Vein Injury
- Trial name
- VUERT (NCT03293836)
- Testing
- Radiofrequency ablation, Multilayer Compressive Bandage
- Where
- Brazil
- Volunteers
- 84 people
- Sponsor
- Juliana Puggina
Coronary Artery Bypass Grafting
Sealing Moderate Coronary Saphenous VEin Graft Lesions With Paclitaxel-Eluting Stents
Hypothesis: Sealing moderate SVG lesions with paclitaxel-eluting stents reduces cardiac events (death, myocardial infarction, target vessel revascularization) over the duration of follow-up.
- Trial name
- VELETI II (NCT01223443)
- Testing
- Paclitaxel eluting stent
- Where
- Canada
- Volunteers
- 125 people
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec
Venous Leg Ulcer
DEep VEin Lesion OPtimisation (DEVELOP) Trial
This is a prospective, single centre, randomised controlled, feasibility study recruiting patients with lower limb venous ulceration and Great Saphenous incompetence.
- Trial name
- Develop (NCT03640689)
- Testing
- Endovenous ablation + iliac US +/- iliac stenting, Endovenous ablation of Great Saphenous Vein
- Where
- 2 sites in Ireland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National University of Ireland, Galway, Ireland
Varicose Vein of Lower Limbs
Catheter-directed Foam Sclerotherapy With Tumescence
Foam sclerotherapy has been established as another option of treatment for varicose veins of the lower limbs. Its advantages are the application to patients with high surgical risk and immediate return to usual activities.
- Trial name
- NCT02753270
- Testing
- Short catheter, Long catheter preceded by tumescence
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Coronary Artery Disease
Graft Patency Analysis of the Right Coronary Artery System
The ideal grafts for the right coronary artery system in coronary artery bypass surgery remain controversial. The objective of this study is to compare the long-term patency of a right gastroepiploic artery and a saphenous vein…
- Trial name
- NCT01559350
- Testing
- A right gastroepiploic artery in situ grafting, A saphenous vein grafting
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Samsung Medical Center
Coronary Artery Bypass, Arteriosclerosis
The SOS (Stenting Of Saphenous Vein Grafts) Trial
The main purpose of this study is to determine whether implantation of a paclitaxel-eluting stent (Taxus™) in saphenous vein graft lesions will reduce the incidence of in-stent restenosis after 12 months when compared to a…
- Trial name
- NCT00247208
- Testing
- Taxus polymer-based paclitaxel-eluting stent, Express 2 bare metal stent
- Where
- 5 sites in United States, Greece
- Volunteers
- 80 people
- Sponsor
- North Texas Veterans Healthcare System
Venous Insufficiency
Radiofrequency Ablation vs Conventional Surgery for Superficial Venous Insufficiency
The current study was a double blind randomised controlled trial that compared radiofrequency ablation (RFA) versus conventional surgery (CS) in patients who served as their own controls and who had intact great saphenous veins…
- Trial name
- NCT02588911
- Testing
- Conventional Surgery, Radiofrequency Ablation
- Where
- Brazil
- Volunteers
- 18 people
- Sponsor
- Nelson Wolosker
Coronary Artery Disease, Saphenous Vein Graft Patency
Surgical Revascularization Outcomes After Oral Anticoagulation or Antiplatelets
The primary purpose of this study is to evaluate whether treatment with oral anticoagulation or oral anticoagulation and aspirin is better than aspirin alone in cardiovascular outcomes and saphenous graft patency in patients…
- Trial name
- SCOOP (NCT03605433)
- Testing
- Rivaroxaban
- Where
- Portugal
- Volunteers
- 100 people
- Sponsor
- Unidade Local de Saúde de Coimbra, EPE
Surgical Wound Infection, Coronary Artery Bypass
Ultrasound to Prevent Leg Wound Complications in Heart Bypass.
The long saphenous vein is traditionally harvested for use as a conduit in coronary artery bypass grafting surgery. Currently, the long saphenous vein is not imaged prior to surgery.
- Trial name
- NCT02307084
- Testing
- Ultrasound imaging of the long saphenous vein
- Where
- United Kingdom
- Volunteers
- 55 people
- Sponsor
- University Hospitals Bristol and Weston NHS Foundation Trust
Restenosis, Myocardial Infarction
Bioabsorbable Versus Durable Polymer Drug Eluting Stent (DES): a Meta-analysis
Evidence supporting use of bioabsorbable polymer drug eluting stents (BP-DES) is uncertain. Thus the investigators planned a meta-analysis to compare outcomes of BP-DES versus PP-DES in obstructive coronary artery disease.
- Trial name
- NCT01466634
- Testing
- percutaneous coronary intervention with stent
- Where
- Italy
- Volunteers
- 6,221 people
- Sponsor
- Azienda Ospedaliero Universitaria Maggiore della Carita
Varicose Veins
Endovenous Radiofrequency Versus Laser Ablation for the Treatment of Great Saphenous Vein Reflux
our aim is to compare early outcomes following EVL 1320 nm and segmental RF in a randomized study.
- Trial name
- NCT02080013
- Testing
- radiofrequency
- Volunteers
- 5 people
- Sponsor
- Ain Shams University
Varicose Veins, Venous Reflux
Comparison of Zero- and Two-centimeter Distance From Sapheno-femoral Junction in Laser Ablation of Varicose Vein
EVLA is used in in treating refluxing veins, commonly the GSV. The tip of catheter is usually placed 2-2.5 cm distal to the sapheno-femoral junction.
- Conditions
- Varicose Veins, Venous Reflux, Venous Insufficiency, Venous Leg Ulcer
- Trial name
- NCT05707169
- Testing
- Saphenous Ablation, Endogenous Laser Ablation (EVLA), mixture of 20 mL 2% lidocaine, 1: 200,000 adrenaline and 20 mL 0.5% levobupivacaine in 1 L of 0.9% saline
- Where
- Egypt
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Deep Vein Thrombosis (DVT), Thrombus in the Peripheral Venous Vasculature
Cleaner Long-tErm Assessment Registry - Venous Insights and Efficacy With eXtended Tracking
The primary objective of this clinical investigation is to evaluate the safety and effectiveness of the Cleaner Vac® Thrombectomy System for the treatment of thrombus in patients with lower extremity proximal deep vein thrombosis…
- Conditions
- Deep Vein Thrombosis (DVT), Thrombus in the Peripheral Venous Vasculature, Venous Embolism, Thrombus in the Central and Peripheral Circulatory System, Including Saphenous Vein Grafts
- Trial name
- CLEAR-VIEW XT (NCT07102160)
- Testing
- Aspiration thrombectomy system
- Where
- 4 sites in United States
- Volunteers
- 185 people
- Sponsor
- Argon Medical Devices
Coronary Artery Disease
Improving the Results of Heart Bypass Surgery Using New Approaches to Surgery and Medication
Surgery for blocked arteries in the heart (coronary artery bypass grafting) can be accomplished using veins from the leg sewn onto the heart to provide an alternate path for blood flow, i.e. 'bypassing' the blockages.
- Trial name
- SUPERIORSVG (NCT01047449)
- Testing
- No-touch SVG harvest vs conventional SVG harvest technique
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- Sunnybrook Health Sciences Centre