Clinical trials: Saphenous Vein
Varicose Vein Disease
FOAM-study, Cost Minimization Study Comparing Surgery Versus Duplex Guided Foam Sclerotherapy of Varicose Veins
Varicose vein disease is a common health problem, which causes much discomfort to patients. Nowadays treatment modalities for greater saphenous veins include surgery and duplex guided foam sclerotherapy.
- Trial name
- NCT01103258
- Testing
- high ligation and stripping (surgery), FOAM
- Where
- Netherlands
- Volunteers
- 460 people
- Sponsor
- Maastricht University Medical Center
Varicose Veins
3-4 Year Outcomes Following Endovenous Steam Ablation for Venous Insufficiency
The aim of this study is to evaluate the long-term effects of endovenous steam ablation (EVSA). Postoperative data at 3-4 year follow-up will be collected from patients treated with EVSA.
- Trial name
- NCT02944331
- Testing
- Endovenous steam ablation
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Lovisenberg Diakonale Hospital
Bleeding
Effect on Bleeding When Using FloSeal Matrix™ in Subjects Undergoing Endoscopic Vein Harvest (EVH)
This is a prospective, randomized trial to see in patients undergoing coronary artery bypass grafting and endoscopically-harvested greater saphenous vein, if using FloSeal Matrix in the endoscopically-harvested saphenous vein…
- Trial name
- NCT00742313
- Testing
- FloSeal Matrix
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Duke University
Varicose Veins
Varithena Versus Endothermal Ablation of the Great Saphenous Vein (VERITAS)
The purpose of this study is to observe insights into the benefits of Varithena compared to Endothermal Ablation (ETA) in the treatment of the great saphenous vein.
- Trial name
- VERITAS (NCT05312970)
- Testing
- Varithena®, FDA-approved Endothermal Ablation (ETA) systems
- Where
- 9 sites in United States
- Volunteers
- 43 people
- Sponsor
- Boston Scientific Corporation
Saphenous Vein Graft Atherosclerosis
Drug-Eluting Stents vs. Bare Metal Stents In Saphenous Vein Graft Angioplasty
Patients who have undergone coronary bypass surgery have had a vein removed from the leg and implanted in the chest to "bypass" blockages in the coronary arteries. These veins are called saphenous vein grafts or SVGs.
- Trial name
- DIVA (NCT01121224)
- Testing
- Bare Metal Stent, Drug-Eluting Stent, Blinded clopidogrel
- Where
- 25 sites in United States
- Volunteers
- 597 people
- Sponsor
- VA Office of Research and Development
Coronary Artery Bypass Grafting Surgery
ESOS (Endoscopic Saphenous Harvesting With an Open CO2 System) Trial
The ESOS (Endoscopic Saphenous harvesting with an Open CO2 System) trial is a prospective randomized trial for coronary artery bypass grafting (CABG) surgery to compare endoscopic open CO2 harvesting system versus conventional…
- Trial name
- ESOS (NCT01121341)
- Testing
- Vein harvesting
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Azienda Ospedaliera San Giovanni Battista
Peripheral Arterial Disease, Peripheral Artery Disease
FRAME, External Support for Lower Limb Autologous Grafts
30 patients will be enrolled in a prospective, multi-center, one-arm study, enrolling patients with claudication and chronic limb ischemia scheduled for lower limb venous bypass grafting on clinical grounds with single segment…
- Trial name
- NCT04003480
- Testing
- FRAME
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Vascular Graft Solutions Ltd.
Coronary Artery Disease
VENEK: Healing in Different Vein Harvesting Methods During Aortocoronary Coronary Artery Bypass Graft Surgery (CABG)
The VENEK trial is a randomized, prospective trial to compare economic parameters, quality of life and wound healing after endoscopic vein harvesting versus open vein harvesting.
- Trial name
- NCT00180388
- Testing
- endoscopic vein harvesting, open vein harvesting
- Where
- 2 sites in Germany
- Volunteers
- 300 people
- Sponsor
- Boston Scientific Corporation
Greater Saphenous Vein Injury
MOCA Versus RFA in the Treatment of Primary Great Saphenous Varicose Veins
The newly developed Mechanochemical Endovenous Ablation (MOCA) device uses a technique that combines mechanical endothelial damage using a rotating wire with the infusion of a liquid sclerosant.
- Trial name
- MARADONA (NCT01936168)
- Testing
- Mechanochemical Endovenous Ablation (MOCA), Radiofrequency ablation (RFA)
- Where
- 5 sites in Netherlands
- Volunteers
- 213 people
- Sponsor
- Rijnstate Hospital
Varicosis
Early Outcome of Mechanochemical Endovenous Ablation
More than 25 percent of the general population suffers from varicose veins, which has a considerable impact on quality of life. Nowadays endovenous treatment modalities for great saphenous incompetence are widely accepted.
- Trial name
- ClariVein-2 (NCT01459263)
- Testing
- ClariVein
- Where
- 2 sites in Netherlands
- Volunteers
- 124 people
- Sponsor
- Rijnstate Hospital
Coronary Artery Bypass Grafting (CABG) Surgery, Saphenectomy
Adductor Canal Block: Efficacy in Postoperative Pain Management for Cardiac Surgery
Adductor Canal Block: Efficacy in Postoperative Pain Management for Cardiac Surgery
- Trial name
- AddEase (NCT07732465)
- Testing
- Aductor canal bloc, Control adductor canal block
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Montreal Heart Institute
Varicose Veins
A Comparison of Specialized Versus Standard Compression After Saphenous Ablation
The purpose of this study is to determine if the use of specialized compression garments, in comparison to standard compression, improves early patient outcomes after endovenous ablation.
- Trial name
- NCT01332838
- Testing
- Compression stockings, compression stockings (Sigvaris )
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Washington
Stenosis
PMS Retrospective Study of WIRION Performance in Patients Undergoing Saphenous Vein Graft (SVG) Intervention
The objective of this study is to collect data on the use of the WIRION system in Patients undergoing Percutaneous Intervention of Saphenous Vein Graft (SVG).
- Trial name
- NCT02373852
- Testing
- Saphenous vein graft (SVG) stenting
- Where
- Israel
- Volunteers
- 12 people
- Sponsor
- Gardia Medical
Varicose Veins of Lower Limb, Venous Insufficiency of Leg
Clinical Outcomes, Safety, and Cost-Effectiveness Analysis of Two Catheters (Xianrui Da and Medtronic) in Radiofrequency Ablation for Varicose Veins
This study aims to systematically compare the clinical efficacy (venous closure rate and symptom relief rate), safety (perioperative and postoperative complications), and cost-effectiveness (direct medical costs) of domestic…
- Conditions
- Varicose Veins of Lower Limb, Venous Insufficiency of Leg, Vascular Disease，Peripheral
- Trial name
- NCT07046286
- Testing
- Compare the two brands of radiofrequency ablation catheters for the treatment of lower limb varicose veins.
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Recurrent Angina After Coronary Artery Bypass Graft, Graft Failure
Prior CABG Patients Evaluated for Saphenous VeIn grAft DysfUnction and Progression of Coronary arTery Disease
This is a multi-center, observational cohort study including patients with prior coronary artery bypass grafting (CABG) and ≥1 saphenous vein grafts (SVG) presenting with recurrent ischemic symptoms.
- Conditions
- Recurrent Angina After Coronary Artery Bypass Graft, Graft Failure, Coronary Artery Disease Progression
- Trial name
- VIADUCT (NCT04772768)
- Where
- Netherlands
- Volunteers
- 500 people
- Sponsor
- Amsterdam UMC, location VUmc
Varicose Veins
The BRILLIANT Study
This trial was designed as a prospective, multi-center, randomized clinical trial of the FDA-cleared Vari-Lase Bright Tip Fiber compared to commercially available standard bare-tip laser fiber (control) to demonstrate the safety…
- Trial name
- BRILLIANT (NCT00618514)
- Testing
- Bright Tip Laser Fiber, Bare Tip Laser Fiber
- Where
- 7 sites in United States
- Volunteers
- 93 people
- Sponsor
- Vascular Solutions LLC
Venous Reflux
Lake Washington Vascular VenaSeal™ Post-Market Evaluation (WAVES)
The VenaSeal Closure system offers an outpatient treatment option for the permanent closure of lower extremity superficial truncal veins, such as the great saphenous vein (GSV), through endovascular embolization with coaptation.
- Trial name
- WAVES (NCT02585726)
- Testing
- SP-402 VenaSeal™ Closure System
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Lake Washington Vascular
Coronary Artery Disease, Coronary Artery Stenosis
Study of the No-touch Saphenous Vein Graft
Authors hypothesize that "no-touch" saphenous vein as I graft is superior over conventional "no-touch" saphenous vein as free graft in the incidence of graft patency.
- Conditions
- Coronary Artery Disease, Coronary Artery Stenosis, Graft Failure, Cardiac Ischemia
- Trial name
- NCT05757947
- Testing
- Сoronary bypass surgery according to the I-graft method, Сoronary bypass surgery by the method of free conduit
- Where
- Russia
- Volunteers
- 106 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Venous Reflux
ClosureFAST - Radiofrequency Great Saphenous Vein Treatment
The purpose of this study is to confirm that the ClosureFAST system can be used as an alternative to the current ClosurePlus catheter for treating the GSV and to accumulate pivotal data for optimization of the operating…
- Trial name
- NCT00842296
- Testing
- RF ablation (ClosureFAST)
- Volunteers
- 326 people
- Sponsor
- Medtronic Endovascular
Coronary Artery Disease
Multicentre Radial Artery Patency Study: Results of Patency Beyond 5 Years After Coronary Artery Bypass Surgery
Bypass surgery is often required to treat severe coronary heart disease. Either arteries or veins can be used as bypass grafts. We wish to compare the long-term durability of the saphenous vein from the leg to that of the radial…
- Trial name
- RAPS - 5 years (NCT00187356)
- Testing
- Radial Artery and Saphenous Vein Grafts Randomized to either right coronary or left circumflex coronary artery territories
- Where
- 13 sites in Canada, New Zealand
- Volunteers
- 269 people
- Sponsor
- Sunnybrook Health Sciences Centre