Clinical trials: Sarcopenia, open to volunteers
Sarcopenia, Acute Lymphoblastic Leukemia
Physical Activity and Exercise During Early Treatment Phases for Childhood Acute Lymphoblastic Leukaemia to Protect Against Muscle Loss and Improve Frailty Outcomes
This is a small trial testing out a new approach before doing a bigger study. Researchers are observing a group of children/adolescents (ages 5-17) with acute lymphoblastic leukemia (ALL) and testing a physical activity and…
- Trial name
- PROTECT (NCT07325305)
- Testing
- Exercise
- Where
- Australia
- Volunteers
- 60 people
- Sponsor
- Murdoch Childrens Research Institute
COPD, Emphysema
Implementation of a Sarcopenia Clinic to Diagnose and Treat Skeletal Muscle Loss Due to COPD
Sarcopenia, or skeletal muscle loss, impacts up to 40% of COPD patients and is a major cause for morbidity and mortality. Despite the high clinical significance of sarcopenia in COPD, the diagnosis remains elusive because…
- Conditions
- COPD, Emphysema, Sarcopenia
- Trial name
- NCT07059637
- Testing
- Multidisciplinary clinic evaluation, COPD standard of care
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- The Cleveland Clinic
Malnutrition, Cirrhosis, Liver
Comparison of Nutritional Screening Tools in Liver Cirrhosis Patients
This study compares two nutritional screening questionnaires in cirrhotic patients. All patients will be assessed with both questionnaires, besides a complete nutritional assessment.
- Trial name
- NCT04502719
- Testing
- Nutritional screening.
- Where
- Spain
- Volunteers
- 46 people
- Sponsor
- Hospital Clinic of Barcelona
Malnutrition, Calorie, Sarcopenia
Malnutrition Screening Study
This is a non-interventional, cross-sectional, non-randomized, observational study to screen for the risk of malnutrition and sarcopenia in outpatients aged 18 and over who attend hospital clinics for any reason in Turkey.
- Trial name
- NCT07256925
- Where
- 69 sites in Turkey (Türkiye)
- Volunteers
- 7,500 people
- Sponsor
- Abbott Nutrition
Obesity, Sarcopenia
Chrono-restricted Diet and Physical Activity as a New Preventive Strategy for Sarcopenia in Postmenopausal Women With Obesity and Type 2 Diabetes
The aim of TIMEDIAB is to demonstrate that early TRE (eTRE) combined to late (afternoon) exercise will outperform eTRE combined to morning exercise on muscle function as primary endpoint, and glucose homeostasis as secondary…
- Conditions
- Obesity, Sarcopenia, Post Menopause, Type 2 Diabetes
- Trial name
- TIMEDIAB (NCT07075133)
- Testing
- Antidiabetic diet (control), eTRE diet, Physical activity in the morning
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Ageing Well
Eccentric Exercise in Community-dwelling Older Adults
The goal of this clinical trial is to evaluate the feasibility, acceptability, and preliminary effectiveness of a 12-month eccentric-biased strengthening programme in community-dwelling older adults aged 65 years and older.
- Trial name
- HEX:AGEUK (NCT07916935)
- Testing
- Eccentric exercise intervention
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Northampton
Sarcopenia, Preoxygenation
Comparison of the Time to Reach End-Tidal Oxygen Value of 90 and Oxygen Reserve Index Decline Times During Preoxygenation in Sarcopenic and Non-Sarcopenic Patients
The purpose of this study is to compare the time required to reach an end-tidal oxygen (EtO2) value of 90% and the time until the Oxygen Reserve Index (ORI) drops below 0.55 during preoxygenation in sarcopenic and non-sarcopenic…
- Conditions
- Sarcopenia, Preoxygenation, Oxygen Reserve Index
- Trial name
- NCT06847672
- Testing
- preoxygenation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara City Hospital Bilkent
Knee Osteoarthritis, Low Level Laser Therapy
Low-Level Laser Therapy in Knee Osteoarthritis: Effects on Clinical Outcomes, Femoral Cartilage Thickness and Regional Sarcopenia
It was designed as a single-center, prospective, randomized controlled study. The study consists of two groups. Both groups of patients will receive a conventional home based exercise program.
- Conditions
- Knee Osteoarthritis, Low Level Laser Therapy, Regional Sarcopenia, Exercise Theraphy
- Trial name
- NCT07078877
- Testing
- home based exercise, Low Level Laser Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Ankara Etlik City Hospital
Sarcopenia in Elderly, Falls
Prevalence of Sarcopenia-Promoting Medicines in Patients With Sarcopenia and Falls
Sarcopenia, characterised by the loss of muscle mass and function, is a common condition among the elderly and is often associated with increased risk of falls.
- Trial name
- NCT07127692
- Testing
- Strength, Assistance with walking, Rise from a chair, Climb stairs, and Falls (SARC-F) questionnaire, Hand grip strength, Timed Up and Go test
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Medway NHS Foundation Trust
Spinal Stenosis Lumbar, Sarcopenia
Sarcopenia and Interlaminar Epidural Steroid Injection Outcomes in Lumbar Spinal Stenosis
This prospective observational study aims to investigate the association between sarcopenia and clinical outcomes following interlaminar epidural steroid injection in patients with lumbar spinal stenosis.
- Trial name
- NCT07855419
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Marmara University
Sarcopneia in Elderly Individuals
Impact of Lower Limb Neural Mobilization on Neuromuscular Function and Calf Muscle Thickness in Elderly Individuals With Sarcopenia
Sarcopenia is a common age-related condition characterized by a gradual loss of muscle mass, strength, and physical performance.
- Trial name
- NCT07515144
- Testing
- Neural Mobilization, Otago Exercise
- Where
- Malaysia
- Volunteers
- 52 people
- Sponsor
- INTI International University
Sarcopenia, Coxarthrosis
Sarcopenia Screening in Advanced Coxarthrosis: The SARCO-COX Study
The SARCO-COX study evaluates whether screening for sarcopenia (loss of muscle strength and mass) in adults aged 65 years or older with advanced hip osteoarthritis, followed by a structured postoperative exercise program…
- Trial name
- SARCO-COX (NCT07734129)
- Testing
- Intensive Physical Rehabilitation, Preoperative Sarcopenia Screening
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Cancer Abdomen, Elderly (People Aged 65 or More)
Functional Decline and Quality of Life After Gastrointestinal Cancer Surgery in Older Adults
This prospective cohort study will evaluate functional decline, health-related quality of life, and long-term oncological outcomes in adults aged 65 years and older undergoing curative-intent resective surgery for…
- Conditions
- Cancer Abdomen, Elderly (People Aged 65 or More), Quality of Life, Sarcopenia in Elderly
- Trial name
- NCT07412379
- Where
- Colombia
- Volunteers
- 590 people
- Sponsor
- Hospital Universitario Mayor Méderi
Sudden Cardiac Death
Skeletal Muscle Multi-omics Analysis and Risk Tailoring in Sudden Cardiac Death
This study is designed as a prospective, single-center, observational cohort study (the SMART-SCD Study, full name: Skeletal Muscle Multi-omics Analysis and Risk Tailoring in Sudden Cardiac Death), which enrolls high-risk…
- Trial name
- SMART-SCD (NCT07476456)
- Where
- China
- Volunteers
- 421 people
- Sponsor
- China National Center for Cardiovascular Diseases
Sarcopenia
Effect of Essential Aminoacid Supplementation and Exercise on Skeletal Muscle Function in Hemodialysis Patients
Sarcopenia can be easily observed in patients with hemodialysis. However, there were few studies on the precise concept and diagnostic criteria for sarcopenia in patients with hemodialysis.
- Trial name
- NCT05884138
- Testing
- exercise and nutritional support
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Chungnam National University Hospital
Physical Performance Decline in Older Adults, Sarcopenia
Clinical Relevance of Ultrasound-based Intramuscular Fat Infiltration Assessment in Hospitalized Older Adults (FATUS-OLD)
Sarcopenia in older adults is associated not only with loss of muscle mass but also with deterioration of muscle quality, particularly intramuscular fat infiltration.
- Conditions
- Physical Performance Decline in Older Adults, Sarcopenia, Muscle Fat Infiltration
- Trial name
- FATUS-OLD (NCT07411547)
- Where
- France
- Volunteers
- 115 people
- Sponsor
- Nantes University Hospital
Coginitive Dysfunction, Compensated Liver Cirrhosis
Examining the Effects of Different Resistive Exercise Programs in Individuals With Compensated Liver Cirrhosis
Reasons such as sleep disorders, depression, decreased independence in daily living activities and decreased quality of life, which are seen in the majority of liver cirrhosis patients, can cause cognitive dysfunction, especially…
- Conditions
- Coginitive Dysfunction, Compensated Liver Cirrhosis, Physical Dysfunction, Sarcopenia
- Trial name
- NCT06749340
- Testing
- Assigned Interventions, Face-to-face Exercise, Home-based Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Bahçeşehir University
Healthy, Perimenopausal Depression
Multidimensional Determinants of Functional Health In Women Aged 45-60
The goal of this observational study is to learn about the multidimensional determinants of functional health in women aged 45 to 60 years.
- Conditions
- Healthy, Perimenopausal Depression, Menopausal Complaints, Bone Mineral Density
- Trial name
- NCT07667699
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kartal City Hospital
Sarcopenia
Austrian Biobanking Study for Sarcopenia
The investigators aim to set up a biobanking study in Graz, Austria, to study sarcopenia in liver cirrhosis and chronic inflammatory bowel disease by collecting a standardized dataset including routine clinical and biochemical…
- Trial name
- ASGSC (NCT06632743)
- Where
- Austria
- Volunteers
- 1,000 people
- Sponsor
- Medical University of Graz
Exercise Training and Sarcopenia
Time Efficient Exercise to Reverse Sarcopenia and Improve Cardio-metabolic Health
Participants will be 60-80 y men and women who vary their physical activity (steps/day) while their lipid metabolism is studied (n=24).
- Trial name
- NCT04641117
- Testing
- Exercise
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin