Clinical trials: Sarcopenia in Elderly
Sarcopenia, Elderly
Omega 3, Leucine, Probiotic Lactobacillus Paracasei PS23 on Muscle Mass in Sarcopenic Subjects
The purpose of the study is to evaluate the effect of supplementation with a nutritional blend based on Omega 3 fatty acids, the probiotic leucine Lactobacillus paracasei PS23 (OLEP), on muscle mass recovery in sarcopenic…
- Conditions
- Sarcopenia, Elderly, Omega 3
- Trial name
- NCT04702087
- Testing
- OLEP
- Where
- Italy
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Azienda di Servizi alla Persona di Pavia
Sarcopenia
Effectiveness of Nutrition and Exercise Interventions in Older Adults With Sarcopenia in Can Gio District, Ho Chi Minh City
Sarcopenia is an age-related condition characterized by progressive loss of muscle mass, muscle strength, and physical performance, which may adversely affect functional capacity and quality of life in older adults.
- Trial name
- HMUIRB1078 (NCT07761091)
- Testing
- Health education, Physical Activity Intervention, Individualized Nutritional Counseling
- Where
- Vietnam
- Volunteers
- 90 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Sarcopenia
Study of Inactivity on Metabolism of Elderly Muscles
Skeletal muscle mass declines with inactivity (casting is a good example) and increases with activity (such as weightlifting). Whether muscle mass increases or decreases, is determined by whether more new proteins within muscle…
- Trial name
- NCT01818609
- Testing
- Step reduction
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- McMaster University
Aging
SArcopenia Prevalence in Frail Older Adults. SAF Study
The age-associated loss of lean mass is a defining parameter of sarcopenia and may lead to various negative health outcomes such as impairment of physical performance and disability.
- Trial name
- SAF (NCT02903992)
- Testing
- Dual-energy X-ray absorptiometry (DXA)
- Where
- France
- Volunteers
- 225 people
- Sponsor
- University Hospital, Toulouse
Sarcopenia, Muscle Weakness
Foot Core Exercise Program on Balance Control and Walking in Aged Sarcopenia
In modern society with an increasing aging population, recent literature has defined sarcopenia as a significant reduced mass and function of skeletal muscle with physical limitations due to aging.
- Conditions
- Sarcopenia, Muscle Weakness, Walking, Difficulty, Balance Control
- Trial name
- NCT05750888
- Testing
- integrated exercise therapy with 3D printing exerciser for training intrinsic foot muscles, regular exercises for the elderly
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Buddhist Tzu Chi General Hospital
Colorectal Cancer, Sarcopenia
Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer
This study will examine the association between low muscle mass (myopenia) at diagnosis and chemotherapy toxicity in older adults with newly diagnosed advanced colorectal cancer.
- Trial name
- M&M (NCT03998202)
- Where
- 147 sites in United States
- Volunteers
- 300 people
- Sponsor
- Wake Forest University Health Sciences
Sarcopenia, Body Weight Changes
Effects of Resistance Training on Physical Performance, Health and Quality of Life in Elderly (RTCHealth)
Physical exercise is considered an important intervention for promoting well-being and healthy aging. The purpose of the present study was to determine the effects of moderate-to-high intensity resistance training circuit on…
- Conditions
- Sarcopenia, Body Weight Changes, Quality of Life
- Trial name
- RTCHealth (NCT03551132)
- Testing
- Exercise test
- Where
- Spain
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Osteoporosis, Sarcopenia
Comprehensive Risk Assessment and Prevention Plan of Osteoporosis and Sarcopenia for the Elderly Participating in Community-based Long-term Care Services
The purpose of this project is: 1. Provide the epidemiological data of the prevalence, incidence, and risk factors of osteoporosis and sarcopenia among the elderly in rural areas. 2.
- Conditions
- Osteoporosis, Sarcopenia, Frailty
- Trial name
- NCT05104034
- Testing
- Osteoporosis screening and treatment as needed, Sarcopenia, Exercise
- Where
- Taiwan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Sarcopenia, Frailty at Older Adults
Targeting Sarcopenia and Frailty: Multicomponent Exercise With Focal Muscle Vibration
This study aimed to evaluate the efficacy of multicomponent exercises (aerobic exercises, strength exercises, and balance exercises), individualized with the application of a focal muscle vibration machine at the lower…
- Conditions
- Sarcopenia, Frailty at Older Adults, Cognitive Impairment, Adherence
- Trial name
- NCT07049809
- Testing
- Focal Muscle Vibration, Multicomponent Exercise
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Sarcopenia, Muscle Loss
Biomarkers of Sarcopenia and Frailty in Geriatric Patients
During the last decades there has been an increase in the relative proportion and life expectancy of elderly people. Hence, the number of elderly with diseases and disabilities related to aging will increase and consequently…
- Conditions
- Sarcopenia, Muscle Loss, Fall Patients
- Trial name
- BioFrail (NCT05795556)
- Testing
- Assessing sarcopenia and potential biomarkers of sarcopenia in fall patients
- Where
- Denmark
- Volunteers
- 508 people
- Sponsor
- Herlev and Gentofte Hospital
Sarcopenia, Aging
Dual-benefits of Aerobic and Resistance Training
This study evaluates the effect of three different exercise strategies on physical function in older adults. Participants will be randomly assigned to one of three exercise groups: resistance training, moderate-intensity…
- Conditions
- Sarcopenia, Aging, Disability Physical
- Trial name
- DART (NCT03978572)
- Testing
- Resistance Training, Moderate-Intensity Continuous Cycling, High-Intensity Interval Cycling
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ohio University
Aging, Sarcopenia
Mycoprotein as the Basis of a Sustainable Diet to Support Muscle Mass Maintenance and Reconditioning in Older Adults.
A hallmark of ageing is loss of skeletal muscle mass and strength (sarcopenia). Sarcopenia is explained, partially, by reduced responsiveness of muscle to dietary protein.
- Trial name
- MASS (NCT04325178)
- Testing
- Protein, calorie and macronutrient controlled diet, derived from either omnivorous or non-animal sources, alongside unilateral resistance exercise, over a three-day period.
- Where
- United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Frailty at Older Adults, Sarcopenia
A Clinical Study on the Improvement of Frailty and Sarcopenia in Elderly Community Residents Through Pulsed Electromagnetic Field Therapy
The entire clinical study will be conducted strictly following the following procedure: 1) Informed Consent If you decide to participate in this trial, we will first ensure that you fully understand the research purpose…
- Trial name
- NCT07834697
- Testing
- Standard treatment with pulsed magnetic therapy apparatus, Fake stimulation therapy with pulse magnetic therapy device
- Volunteers
- 100 people
- Sponsor
- Xuanwu Hospital, Beijing
Aging, Sarcopenia
Leucine Co-ingestion and Myofibrillar Protein Synthesis in Older Adults
The loss of muscle mass with aging is associated with a dysregulation of muscle protein synthesis (MPS) that is generally characterized by a suppressed MPS response to protein ingestion.
- Trial name
- NCT02371278
- Testing
- Leucine
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- McMaster University
Frailty, Sarcopenia
Clinical Evaluation, Biomarkers and Metabolomics of Sarcopenia in Frail Older Adults at Ambulatory Clinics
Sarcopenia related mobility dysfunction was a preventable presentation in transitional variation of frailty. However, the definition, associated risk factors, clinical course and outcome of sarcopenia in Taiwanese older adults…
- Trial name
- EC0991002-E (NCT02073370)
- Where
- Taiwan
- Volunteers
- 350 people
- Sponsor
- National Taiwan University Hospital
Sarcopenia in Elderly, Hospital Associated Disability
Preventing Hospital Associated Disability in Older Patients: Individualized Nutrition and Exercise Strategy
Aproximately a third of persons older than 70 years lose physical function and ability to take care of themselves during a stay at a hospital. This is associated to an increased risk of readmission and mortality.
- Conditions
- Sarcopenia in Elderly, Hospital Associated Disability, Malnutrition Elderly, Physical Function
- Trial name
- PrevHAD RCT (NCT07373587)
- Testing
- Exercise
- Where
- Denmark
- Volunteers
- 360 people
- Sponsor
- Bispebjerg Hospital
Sarcopenia
TRX Suspension Training for Sarcopenia in Older Men
This randomized controlled trial evaluated the effects of a 12-week TRX suspension training program on physical fitness, gait performance, and selected blood biomarkers in older men with sarcopenia.
- Trial name
- TRX-SARC (NCT07398092)
- Testing
- TRX Suspension Training, Usual Daily Activities
- Where
- China
- Volunteers
- 36 people
- Sponsor
- WeiJin Zhang
Frailty, Sarcopenia
Combining Nutrition Supplementation With an Exercise Program in Elderly Malnourished Frail Patients After Hospital Stay
The objective of this study is to investigate the feasibility of a combined nutritional and home-based exercise intervention in elderly, malnourished, frail patients after hospital discharge.
- Conditions
- Frailty, Sarcopenia, Malnutrition; Protein
- Trial name
- NCT05325697
- Testing
- Intervention consisting of a multicomponent exercise program combined with an oral nutritional supplement
- Volunteers
- 15 people
- Sponsor
- University Department of Geriatric Medicine FELIX PLATTER
Immune Senescence, Sarcopenia
Effects of PS-IPC Supplementation on Muscle Mass and Functional Outcomes in Older Adults
Sarcopenia, the age-associated loss of skeletal muscle mass and strength, is a frequent precursor to functional impairment, disability, falls, and loss of independence in the elderly.
- Trial name
- PS-IPC (NCT00926250)
- Testing
- Oral PS-IPC supplement
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Sarcopenia, Aging
Effects of Polyphenol Supplementation and Exercise on Physical Performance in Older Adults
After approximately age 40 years, individuals experience a natural loss of muscle mass, strength, and physical function that is linked to higher risks of falls, disability, loss of independence, and mortality.
- Conditions
- Sarcopenia, Aging, Frailty
- Trial name
- NCT07441343
- Testing
- Polyphenol Rich-Extract, Resistance Band-Based & Aerobic Stationary Cycling Exercise
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Dr. Chris McGlory, PhD