Clinical trials: Sarcopenia in Elderly
Obesity, Sarcopenia
Prevalence of Osteosarcopenic Obesity in Older Adults
Osteosarcopenic Obesity (OSO) is a syndrome characterized by the loss of bone and muscle in addition to increase in the fat tissue as a result of aging process.
- Conditions
- Obesity, Sarcopenia, Osteopenia, Osteoporosis
- Trial name
- NCT04288401
- Where
- Turkey (Türkiye)
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Sarcopenia in Elderly
Blood Flow Restriction Training in Acute Geriatric Rehabilitation
Background: Older adults have a reduced ability to build and maintain muscle mass due to age-related changes in the muscular system.
- Trial name
- NCT07291765
- Testing
- Stationary Bike + Blood-Flow-Restriction, Acute geriatric rehabilitation + No additional Intervention
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- University Hospital, Bonn
Knee Osteoarthritis, Ultrasound Exams
Applications of Ultrasound and Physical Parameters in Assessing Fall Risk in Patients With Knee Osteoarthritis
Falls are a significant issue for patients with knee osteoarthritis, as they can lead to hospitalization or even more severe consequences. Therefore, it is crucial to assess fall risk early in rehabilitation clinics.
- Conditions
- Knee Osteoarthritis, Ultrasound Exams, Fall Risk, Sarcopenia in Elderly
- Trial name
- UPPFR-KneeOA (NCT06882928)
- Where
- Taiwan
- Volunteers
- 250 people
- Sponsor
- National Taiwan University Clinical Trial Center
Sarcopenia, Geriatric
Effect Of Ophiochepalus Striatus Extract On Serum IGF-1 And IL-6 Levels In Elderly Patients With Sarcopenia
The goal of this Clinical Trial is to analyze effect of Ophiochepalus striatus extract on serum IGF-1 and IL-6 levels in elderly patients with sarcopenia. The main questions it aims to answer are: 1.
- Conditions
- Sarcopenia, Geriatric, Muscle Mass, Muscle Strength
- Trial name
- NCT05869383
- Testing
- Ophiochepalus striatus extract
- Where
- Indonesia
- Volunteers
- 80 people
- Sponsor
- Universitas Sriwijaya
Sarcopenia in Elderly, Muscle Atrophy
Effects of Cyclical Blood Flow Restriction Exercise on Muscle Hypertrophy and Capillaries in Older Adults
The purpose of this study was to learn if low-load resistance exercise combined with cyclical blood flow restriction (BFR) could improve small blood vessel structure and muscle size in older adults.
- Conditions
- Sarcopenia in Elderly, Muscle Atrophy, Aging
- Trial name
- NCT07689487
- Testing
- Blood Flow Restriction (BFR), Conventional Low-Load Resistance Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Elderly Women, Sarcopenia
Dietary Supplementation With Omega-3 Fatty Acid in Muscle Response
Both aging and other factors associated with it may contribute to the development of sarcopenia, such as lack of physical activity, inadequate food intake, hormonal changes and age-related increases in cytokine levels.
- Trial name
- NCT03462771
- Testing
- Fish oil, sunflower oil
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Eduardo Ferriolli
Sarcopenia, Sarcopenia in Elderly
Determination of Skeletal Muscle Mass Index Values in the Turkish Population Using Dual Energy X-Ray Absorptiometry
Sarcopenia is defined by the European Working Group on Sarcopenia in Older People (EWGSOP) as "a syndrome characterized by progressive and generalized loss of skeletal muscle mass and strength, carrying a risk of adverse outcomes…
- Trial name
- NCT07510009
- Where
- Turkey (Türkiye)
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Sarcopenia in Elderly
Feasibility of Egg White Pudding Supplementation for Individuals in Personal Care Home Centres Needing Dietary Supplementation
This trial is an open-label randomized controlled parallel arm feasibility trial. 54 residents in care homes receiving nutrition supplementation (minimum 40% of each sex, ≥ 50 years of age).
- Trial name
- NCT07805993
- Testing
- Egg White Pudding, Nestle Resource
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Seven Oaks Hospital Chronic Disease Innovation Centre
Sarcopenia
Integrated Physical Training With Protein Diet in Older Adults With Sarcopenia Symptoms.
Sarcopenia is the major health concern and common consequence of COVID-19 in the aging population. Moreover, this clinical condition has not been considered in usual physical rehabilitation practice, and its optimal protein…
- Trial name
- NCT05224453
- Testing
- Physical training and high protein diet, Physical training and low protein diet
- Where
- Saudi Arabia
- Volunteers
- 76 people
- Sponsor
- Prince Sattam Bin Abdulaziz University
Critical Illness, Sarcopenia
Effect of Protein, Mobility Therapy and Electric Stimulation on Recovery in Older ICU Survivors
Older ICU survivors with ICU acquired weakness (ICUAW) are malnourished, sarcopenic, and functionally debilitated as a consequence of the high burden of comorbidities common in the elderly.
- Conditions
- Critical Illness, Sarcopenia, ICU Acquired Weakness
- Trial name
- ProMoTE (NCT05326633)
- Testing
- MRP and High Protein Supplement (HPRO) and Neuromuscular Electric Stimulation (NMES)
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- University of Maryland, Baltimore
Sarcopenia, Bladder Cancer
SArcopenia, Mobility, PHYsical Activity and Post-operative Risk of Bladder Carcinoma in the Elderly
Sarcopenia is associated with lower prognosis in solid tumors, but this has not been studied in bladder carcinoma requiring cystectomy.
- Trial name
- SAMPHYR (NCT03362801)
- Testing
- sarcopenia and mobility measurement
- Where
- 3 sites in France
- Volunteers
- 69 people
- Sponsor
- University Hospital, Caen
Protein Metabolism
Prandial Metabolic Phenotyping in Sarcopenic Older Adults Comparing Plant Based and Whey Based Protein
The researchers overall objective is to determine whether plant and animal protein based proteins affect the anabolic responses across aging populations differently due to specific changes in the essential amino acids (EAA) and…
- Trial name
- NCT06628349
- Testing
- Whey Protein Isolate 90%, Soy Protein Isolate (90% Protein), Organic Pea Protein Isolate
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Sarcopenia
Clinical Trial of Astaxanthin Formulation With Exercise in Sarcopenia Elderly
The primary objective of this trial is to evaluate the effect of oral administration of an Astaxanthin formulation compared to placebo after one month alone and after an additional 3 months of exercise training on mitochondrial…
- Trial name
- NCT03368872
- Testing
- Astaxanthin formulation, Exercise training
- Where
- 2 sites in United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Astavita, Inc.
Hip Arthritis, Sarcopenia
Effects of Whey and Collagen on FFM, Muscle Strength and Wound Healing in Elderly Surgical Patients
The purpose of the study is to compare the effect of whey protein and collagen on fat free mass, muscle strength, functional ability, wound healing and life quality in elderly patients undergoing elective knee- or hip surgery…
- Conditions
- Hip Arthritis, Sarcopenia, Knee Arthritis
- Trial name
- NCT04496856
- Testing
- Whey protein and Collagen supplementation
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- University of Copenhagen
Sarcopenia
Insulin and Sarcopenia in the Elderly
Muscle loss with aging is a significant contributor to disability in older people. Our general hypothesis is that loss of muscle with aging, known as sarcopenia, may be due to inability of muscle to grow in response to insulin.
- Trial name
- NCT00690534
- Testing
- Insulin Regular, L-NMMA, Sodium Nitroprusside
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Low Muscle Strength, Malnutrition
Efficacy of Oral Nutritional Supplement in Community-Dwelling Adults Following Acute Care
The study aims to determine the effects of Oral Nutritional Supplement (ONS) added to usual care on body weight compared with usual care alone in community-dwelling adults aged 55 years and older who are at risk of malnutrition…
- Trial name
- NCT07753239
- Testing
- ONS, Standard of Care (SOC)
- Where
- 7 sites in Thailand
- Volunteers
- 304 people
- Sponsor
- Abbott Nutrition
Frailty, Obesity
Slow Gait Speed as an Indicator of Overweight, Dynapenic Obesity and Sarcopenic Obesity in Elderly People in the Community
The goal of this observational study is to evaluate the relationship of gait speed with dynapenic or sarcopenic obesity in community-dwelling older people.
- Conditions
- Frailty, Obesity, Sarcopenia, Sarcopenic Obesity
- Trial name
- SGSF (NCT06413030)
- Testing
- 10 Meter Walk Test
- Where
- Chile
- Volunteers
- 383 people, healthy volunteers welcome
- Sponsor
- University of Americas - Chili
Frail Elderly Syndrome, Emergencies
Frailty and Sarcopenia Outcomes in Emergency General Surgery
1. A retrospective scoping cohort review of adult patients undergoing emergency laparotomy/laparoscopy for acute gastrointestinal (GI) pathology who have had a CT scan of the abdomen(+/- pelvis).
- Conditions
- Frail Elderly Syndrome, Emergencies, Surgery, Sarcopenia
- Trial name
- FrOGS (NCT03534765)
- Testing
- CT abdomen +/- pelvis, Edmunton Frailty Score, Emergency laparotomy for general surgical pathology
- Where
- 10 sites in United Kingdom
- Volunteers
- 294 people
- Sponsor
- Yeovil District Hospital NHS Foundation Trust
Physical Performance Decline in Older Adults, Sarcopenia
Clinical Relevance of Ultrasound-based Intramuscular Fat Infiltration Assessment in Hospitalized Older Adults (FATUS-OLD)
Sarcopenia in older adults is associated not only with loss of muscle mass but also with deterioration of muscle quality, particularly intramuscular fat infiltration.
- Conditions
- Physical Performance Decline in Older Adults, Sarcopenia, Muscle Fat Infiltration
- Trial name
- FATUS-OLD (NCT07411547)
- Where
- France
- Volunteers
- 115 people
- Sponsor
- Nantes University Hospital
Sarcopenia, Memory Loss
Effects of Multidomain Training of Health With Aging (Train-Old)
The current study aims to determine the effect of a multidomain intervention (physical fitness, motivational and cognitive training) on body composition, sarcopenia, cardiovascular health, physical fitness, functional capacity…
- Conditions
- Sarcopenia, Memory Loss, Muscular Atrophy, Cardiovascular Diseases
- Trial name
- Train-Old (NCT05481346)
- Testing
- Multidomain training
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidad de Almeria