Clinical trials: Scar
Post-acne Atrophic Scars
Various Procedural Treatment Options for Post-acne Atrophic Scars
Post acne scars are formed as a result of very inflamed and nodulocystic acne. Most common type of acne scars are atrophic scars and they are further classified on the basis of depth and size of destruction into ice pick, boxcar…
- Trial name
- NCT06770608
- Testing
- micro-needling with topical human actrapid insulin, Micro-needling with topical Platelet rich plasma
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Sheikh Zayed Medical College
Post Surgical Scars, Epidermic Burn
Cicatrix Cream in Post Surgical Scars and Epidermic Burn
The purpose of the study is to assess the effect of CICATRIX (Asian Gotu Kola or Pennywort) usage in the treatment of epidermic burns or post surgical scars. The duration of this phase 2 clinical trial will be two months.
- Trial name
- NCT01018589
- Testing
- Cicatrix cream
- Where
- Cuba
- Volunteers
- 100 people
- Sponsor
- Catalysis SL
Pemphigoid, Benign Mucous Membrane, Gingivitis Hyperplastic
Peridontal and Intestinal Microbiota in Patients With Gingival Scarring Pemphigoid
Patients suffering from Mucous Membrane Pemphigoid with desquamative gingivitis (MMPg) generally present a more degraded periodontal condition compared with controls.
- Trial name
- MICROPC (NCT06291350)
- Testing
- Plaque sampling and stool collection, periodontal examination
- Where
- 3 sites in France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Scar Prevention
Safety and Efficacy Study of EXC 001 to Improve the Appearance of Scars From Prior Breast Surgery
This study will compare how well EXC 001 works to improve the appearance of scars in subjects undergoing breast scar revision surgery. The study will also evaluate the safety of EXC 001 in healthy adult subjects.
- Trial name
- NCT01037413
- Testing
- EXC 001
- Where
- 5 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Pfizer
Keloid Scar
Proof of Concept (POC) Study of the Soliton's Acoustic Scar Reduction (ASR) Treatment for the Treatment of Keloid Scar
To evaluate the safety, and efficacy of the ASR device for the temporary improvement in the appearance of a keloids.
- Trial name
- ASR (NCT04016610)
- Testing
- Soliton's Acoustic Scar Reduction (SAR)
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Soliton
Acne Scars
Comparison of 1550nm Fractional Laser Alone Versus in Combination With Microneedling for the Treatment of Acne Scars
Acne scarring is an unfortunate consequence of inflammatory acne vulgaris that often leads to significant cosmetic and psychosocial impacts.
- Trial name
- NCT03901417
- Testing
- Fraxel Restore (Non-ablative Fractional Laser), Fraxel Restore (Non-ablative fractional laser) and SkinPen (Microneedling Device)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Corneal Scar
Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Subjects With Corneal Scars
This study will enroll subjects with recently formed corneal scars that resulted from a corneal insult presenting and diagnosed within the past approximately 30 days and not less than approximately 7 days.
- Trial name
- NCT06257355
- Testing
- CSB-001 Ophthalmic Solution 0.1%
- Where
- 7 sites in United States
- Volunteers
- 20 people
- Sponsor
- Claris Biotherapeutics, Inc.
Scar
Botox in the Healing of Surgical Wounds of the Neck
The investigators hypothesize that Botox A will reduce scarring and improve healing of surgical neck wounds.
- Trial name
- NCT01177358
- Testing
- Botulinum Toxin Type A, Normal Saline
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Rhinoplasty, Surgical Procedure, Unspecified
Aesthetic and Functional Results of Alar Base Modifications in Rhinoplasty
Rhinoplasty is among the most accomplished aesthetic procedures in Plastic Surgery. The mastery of Alar Base modifications is essential for superior aesthetic results.
- Conditions
- Rhinoplasty, Surgical Procedure, Unspecified, Surgery, Plastic, Cicatrix
- Trial name
- NCT03213548
- Testing
- Alar facial groove incision, Alar facial groove spared
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Post Surgical Scars
Treatment of Surgical Scars With Fractional Photothemolysis Versus Pulse Dye Laser
1. Evaluate the efficacy of the Fraxel SR laser to improve the cosmetic appearance of surgical scars, both in terms of pigmentary and textural changes. 2.
- Trial name
- NCT00685243
- Testing
- Laser treatment
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Henry Ford Health System
Cutaneous Scars
The Effect Of Light On Scar Appearance
The goal of this project is to examine the ability of light exposure to improve the appearance of cutaneous scars.
- Trial name
- NCT00544635
- Testing
- no intervention, light
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Northwestern University
Atrophic Acne Scar
Subcision With CO₂ Laser or PRP vs Subcision Alone in Atrophic Acne Scars
Acne vulgaris is an inflammatory disease of pilosebaceous unit ,leading to different types of scars including atrophic, hypertrophic and keloidal.
- Trial name
- NCT07199608
- Testing
- subcision, subcision+fractional co2 laser, subcision+PRP
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Assiut University
Myocardial Infarction
Changes in Regional and Global Cardiac Contractility After Stimulation in Scar Zone With the NOGA System
Despite a decrease in voltage amplitude in post-infarction scar areas, greater voltage amplitudes are sometimes observed at the time of local extrasystoles mechanically induced by catheters.
- Trial name
- SCARPACE (NCT04757168)
- Testing
- NOGA TM probe
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Toulouse
Zygomatic and Lefort II Fractures, Infraorbital Rim Fixation
Post-operative Lower Eyelid Massage for Prevention of the Lower Eyelid Scare Contracture After Subciliary Approach
Patients were randomly allocated to the lower eyelid massage (experimental) or standard care (control) groups. The massage group received post-operative instructions.
- Conditions
- Zygomatic and Lefort II Fractures, Infraorbital Rim Fixation, Subciliary Approach Repair
- Trial name
- RCT (NCT06311318)
- Testing
- lower eyelid massage
- Volunteers
- 59 people
- Sponsor
- Chiang Mai University
Tissue Adhesion, Gynecologic Surgery
The Assessment of the Use of Anti-Adhesion Agents to Prevent Pelvic Postoperative Adhesions
The aim of this study is to assess the safety and effectiveness of PROTAHERE Absorbable Adhesion Barrier to prevent pelvic postoperative adhesions.
- Trial name
- NCT04063085
- Testing
- PROTAHERE Absorbable Adhesion Barrier, Hyalobarrier Gel, No treatment
- Where
- Taiwan
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- SciVision Biotech Inc.
Scar
Evaluation of the Effect of CGF in Promoting Mechanical-stretch Induced in Vivo Skin Regeneration
The purpose of this study is to evaluating whether autologous Concentrate Growth Factors(CGF) is safe and/or effective to accelerating skin regeneration and soft tissue expansion.
- Trial name
- NCT03406143
- Testing
- CGF injection, Control
- Where
- 2 sites in China
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Cesarean Section Scar
Cesarean Section Scar Evaluation by Saline Contrast Sonohysterography During Hysteroscopy
To apply an existing diagnostic imaging test (saline infusion sonohysterography by Hysteroscopic) to characterize the "filling defect" of a previous cervical cesarean delivery scar in the nonpregnant uterus
- Trial name
- NCT02865655
- Testing
- Hysteroscopic
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
Uterine Scar Defect
Suture of UTerus and Ultrasound Repair Evaluation
This study compares three techniques of uterine closure on myometrium thickness evaluated by ultrasound six months after the primary cesarean.
- Trial name
- SUTURE (NCT01860859)
- Testing
- Closure of the hysterotomy at the time of primary cesarean
- Where
- Canada
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Fibrosis, Scarring
High Fluence Light Emitting Diode-Red Light (LED-RL) in Human Skin
The goal of this study is to establish the safety of high fluence LED-RL from 160 J/cm2 up to 640 J/cm2 in healthy subjects. The hypothesis is that high fluence LED-RL phototherapy is safe in human skin.
- Conditions
- Fibrosis, Scarring, Scar, Wounds
- Trial name
- NCT02630303
- Testing
- LED-RL Phototherapy, Mock Therapy
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jared Jagdeo, MD, MS
Cesarean Section Complications
Laparoscopic Repair of Cesarean Scar Niche
Evaluation of laparoscopy repair of cesarean scar niche in resolution of symptoms related to niche as compared to expectant management.
- Trial name
- NCT04307524
- Testing
- laparoscopic repair, medical treatment in the form of combined hormonal contraception
- Volunteers
- 30 people
- Sponsor
- Zagazig University