Clinical trials: Scar Reduction
Hair Reduction, Tattoo Removal
Clinical Study to Evaluate the Safety and Efficacy of Candela Technology
This is a non-randomized, multi-center, open-label, prospective clinical study evaluating the clinical treatment with Candela Medical Technology.
- Conditions
- Hair Reduction, Tattoo Removal, Wrinkle, Acne
- Trial name
- NCT06202274
- Testing
- Nordlys, Gentle, Picoway, Vbeam, Profound, Profound Matrix, eTwo, Exceed, CO2RE
- Where
- 3 sites in United States, Israel
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Candela Corporation
Burn Scar, Itch Scarring
Novel Strategies for Reducing Burn Scar Itch
The purpose of the study is to see whether using diphenhydramine (Benadryl), famotidine (Pepcid), and cromolyn sodium will decrease burn scar itch.
- Conditions
- Burn Scar, Itch Scarring, Wound
- Trial name
- NCT06801626
- Testing
- Famotidine and 4% topical cromolyn sodium
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Mohs Surgery
Study of EB-001 in Facial Scar Reduction
This study will evaluate the safety and efficacy of EB-001 in improving wound healing and reducing scar formation in patients undergoing Mohs surgery for skin lesions in the forehead area following a single treatment of EB-001…
- Trial name
- NCT03346902
- Testing
- EB-001, 0.9% Sodium Chloride Injection
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Bonti, Inc.
Cicatrix, Wound Healing
Investigation Into the Scar Reduction Potential of Prevascar (Interleukin-10)
The purpose of this study was to investigate the scar-reducing properties of eight doses of intradermal Prevascar (IL-10).
- Trial name
- NCT00984646
- Testing
- Prevascar
- Where
- United Kingdom
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Renovo
Acne Scars - Mixed Atrophic and Hypertrophic, Wrinkle
Fractional Radiofrequency for the Treatment and Reduction of Acne Scars and Wrinkles
The objective of this clinical study is to evaluate the efficacy of fractional RF for the treatment and reduction of acne scarring or facial wrinkles.
- Trial name
- NCT04057768
- Testing
- Venus Viva
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Venus Concept
Surgical Incision
Fractional Radiofrequency for Reduction of Surgical Scar Formation
Safety and Efficacy of Fractional Radiofrequency for the Reduction of Surgical Scar Formation
- Trial name
- NCT05897723
- Testing
- Fractional Radiofrequency
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Venus Concept
Evaluation of Short Scar Periareolar Inferior Pedicle Reduction Mammoplasty in Oncoplastic Breast Surgery
in Our Study we Compare Results of Two Oncoplastic Breast Surgery (Short Scar Reduction Mammoplasty and Wise Pattern Reduction Mammoplasty) as Surgical Treatment of Breast Cancer
in our study we compare results of two oncoplastic breast surgery (short scar reduction mammoplasty and wise pattern reduction mammoplasty) as surgical treatment of breast cancer
- Trial name
- NCT06901180
- Testing
- short scar periareolar inferior pedicle reduction mammoplasty
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Efficiency of Surgical Incision Closure, Post-operative Scar
Use of Prineo in Breast Reduction Surgery
This is a prospective, randomized, controlled, single-blinded study to compare Prineo™ with subcuticular sutures in 20 women undergoing bilateral breast reduction.
- Trial name
- Prineo (NCT01996917)
- Testing
- Prineo
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Columbia University
Cicatrix, Wound Healing
Genomic Changes Associated With the Use of Intradermal Avotermin (Juvista) in Small Wounds in Healthy Male Subjects
The purpose of this study is to further determine the safety and toleration of intradermal avotermin (Juvista), confirm accelerated healing and investigate genomic expression profiles
- Trial name
- NCT00977951
- Testing
- Intradermal avotermin
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Renovo
Reduction of Hypertrophic Skin Scarring
Safety and Efficacy Study of PF-06473871 to Reduce Hypertrophic Scars From Recurring Post-Revision Surgery
The study will compare how well PF-06473871 works versus placebo in reducing skin scarring after scar revision surgery of existing breast scars. The study will also evaluate the safety of PF-06473871 in healthy adult subjects.
- Trial name
- NCT01730339
- Testing
- PF-06473871
- Where
- 40 sites in United States, Germany and 2 more
- Volunteers
- 103 people
- Sponsor
- Pfizer
Cicatrix
Intraoperative Hyaluronic Acid Gel Injection for Improvement of Scar Quality Following Reduction Mammaplasty
The purpose of this study is to determine the efficacy of hyaluronic acid gel injections compared to saline injections in improving scar quality in patients undergoing breast reduction surgery.
- Trial name
- NCT00958425
- Testing
- Hyaluronic acid gel, Saline
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Acne Scars
Clinical Evaluation of Fractional Radiofrequency for the Treatment Acne Scarring
Prospective, single centre, evaluator-blind study of the safety and performance of fractional radiofrequency (RF) for the treatment and reduction of acne scarring.
- Trial name
- NCT03821324
- Testing
- Venus Viva
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Venus Concept
Scar Prevention, Scar Reduction
A Phase 2a Study to Evaluate the Safety and Efficacy of AZX100 in Trocar Sites of Arthroscopic Shoulder Surgery Patients
The purpose of this study was to determine the safety of AZX100 Drug Product and to determine whether it was effective in preventing or reducing scars that were made from trocars following arthroscopic shoulder surgery.
- Trial name
- NCT00811577
- Testing
- AZX100
- Where
- 5 sites in United States
- Volunteers
- 150 people
- Sponsor
- Capstone Therapeutics
Scar
Reducing Side-effects of Autologous Skin Tissue Harvesting
The investigators are doing this research study to learn about how the skin heals after many microscopic skin biopsies are collected.
- Trial name
- NCT02234193
- Testing
- Micro biopsy, Lidocaine with epinephrine
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Congenital Heart Defect, Surgery-Induced Tissue Adhesions
Effects of CoSeal on Bleeding & Adhesions in Pediatric Heart Surgery
This is a prospective, randomized, open-label, blinded-evaluator study that will evaluate the effectiveness of a surgical sealant (CoSeal) composed of biocompatible polyethylene glycol on the formation of mediastinal and…
- Conditions
- Congenital Heart Defect, Surgery-Induced Tissue Adhesions, Hemorrhage
- Trial name
- NCT01330433
- Testing
- CoSeal Surgical Spray Group
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Loma Linda University
Hypertrophic Scar, Burn Scar
Pain and Itch Reduction in Burn Scars Treated With Fractional CO2 Laser
Hypertrophic Burn Scars (HTBS) are often treated with Fractional CO2 laser therapy to improve cosmetic appearance. It has been noted that this leads to a reduction in the pain and itch associated with this type of scars.
- Trial name
- NCT04364217
- Testing
- Luminis ultrapulse fractional ablative carbon dioxide laser
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Surgical Incision
Force Modulating Tissue Bridges for Closure of Vertical Scars in Breast Reduction
This is a prospective, within-subject randomized, single blinded study designed to follow up to forty-two (42) qualified and consenting adult females, 18-65 years of age scheduled for elective breast reduction surgery using a…
- Trial name
- NCT05028816
- Testing
- Side 1: Final layer closure with force modulating tissue bridges (FMTB), Side 1: Final layer dermal closure with poliglecaprone 25 suture, Side 2: Final layer closure with force modulating tissue bridges (FMTB)
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Breast Ptosis, Mammaplasty
Autologous Free Dermal Graft Support in Superior Pedicle Vertical Scar Reduction Mammaplasty
The goal of this observational study is to learn whether using an autologous free dermal graft during breast reduction surgery helps maintain lower breast pole shape over time in women undergoing primary bilateral reduction…
- Conditions
- Breast Ptosis, Mammaplasty, Lower Pole Elongation, Postoperative Breast Pseudoptosis
- Trial name
- NCT07657962
- Testing
- Autologous Free Dermal Graft Support
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Cumhuriyet University Hospital
Ovarian Cysts, Endometriosis
Evaluation of Adhexil Safety and Efficacy in Prevention and/or Reduction of Adhesions in Gynecological Surgery
The objective of this study is to evaluate the safety and efficacy of ADHEXIL™ in preventing and/or reducing post-operative adhesions in patients undergoing surgery involving the ovaries.
- Conditions
- Ovarian Cysts, Endometriosis, Adhesions
- Trial name
- NCT00865488
- Testing
- ADHEXIL
- Where
- 5 sites in United States, Germany and 3 more
- Volunteers
- 80 people
- Sponsor
- OMRIX Biopharmaceuticals