Clinical trials: Scar Tissue
Hypertrophic Scars
Effectivity of Dermatix in Promoting Scar Maturation
The purpose of this research is to demonstrate effectivity of Dermatix in promoting maturation of the scar, versus a control region that will be treated with an indifferent cream.
- Trial name
- NCT00548210
- Where
- Netherlands
- Volunteers
- 25 people
- Sponsor
- Association of Dutch Burn Centres
Adhesion
PMCF Study for COSEAL® in Gynecologic Surgery
The study is a single-arm, retrospective, chart review with a patient questionnaire intended to supplement the patient chart, when necessary.
- Trial name
- NCT05996809
- Testing
- Coseal
- Where
- 2 sites in United States, Italy
- Volunteers
- 200 people
- Sponsor
- Baxter Healthcare Corporation
Polyp of Colon
Linked Color Imaging Versus White Light Endoscopy for the Evaluation of Scars of Non-pedunculated Polyps. LCI Scar Study.
Careful inspection and evaluation of the post-polipectomy scars of polyps greater than 20 mm looking for residual polyp is mandatory. LCI has demonstrated to improve polyp and adenoma detection rate in previous studies.
- Trial name
- LCIScar (NCT04899700)
- Testing
- Linked Color Imaging, White light endoscopy
- Where
- 2 sites in Spain
- Volunteers
- 173 people
- Sponsor
- Hospital Clinic of Barcelona
Obesity, Morbid, Obesity
CiNPT for Abdominoplasties in Post-bariatric Patients Study
The overarching goal of this research is to assess whether the post-operative use of closed-incision Negative Pressure Therapy (ciNPT) accelerates healing of surgical wounds, improves surgical outcomes, and reduces the rate of…
- Conditions
- Obesity, Morbid, Obesity, Obesity, Abdominal, Wound
- Trial name
- CAPS (NCT04214236)
- Testing
- ciNPT group, Control group
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera, Ospedale Civile di Legnano
Sudden Death, Cardiac, Myocardial Scarring
Cardiac Magnetic Resonance - PROgnostic HEart Scar for Sudden Cardiac Death Prediction StudY
The purpose of this observational study is to investigate whether myocardial scar characteristics assessed by cardiac magnetic resonance (CMR) can predict the risk of out-of-hospital sudden cardiac death (SCD) after myocardial…
- Conditions
- Sudden Death, Cardiac, Myocardial Scarring, Myocardial Infarction (MI)
- Trial name
- NCT07137936
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Beijing Anzhen Hospital
Hypertrophic or Keloid Scars
Silicone Gel Versus Onion Extract Gel as Prevention for Postsurgical Scars
Hypertrophic or keloid scars develop for about 39% to 68% of patients after surgery. The subjective opinion of the patient regarding the scar will often constitute the standard for judging the success or failure of the procedure.
- Trial name
- NCT01861119
- Testing
- Silicone gel Kelo-cort™;, Onion extract gel Contractubex™
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- CHA University
Tissue Adhesions
Cine-magnetic Resonance Imaging (MRI) Detecting Intra Abdominal Adhesions
Official title: Sensitivity and predictive value of functional cine magnetic resonance imaging (MRI) detecting intra-abdominal adhesions Background: Adhesions are a frequent problem in abdominal surgery.
- Trial name
- NCT00882167
- Testing
- CineMRI
- Where
- 5 sites in Netherlands
- Volunteers
- 100 people
- Sponsor
- Radboud University Medical Center
Acne Vulgaris, Isotretinoin
Investigation of the Effect of Oral Isotretinoin on Skin Thickness and Elasticity in Patients With Atrophic Acne Scar
Acne scar is a common complication of acne vulgaris (AV). Early and effective treatment of AV has a crucial role in managing both acne and acne scarring.
- Conditions
- Acne Vulgaris, Isotretinoin, Atrophic Acne Scar
- Trial name
- NCT05413200
- Testing
- Isotretinoin
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul Training and Research Hospital
SCAR
An Exploratory Study of Genetic and Clinical Factors for Serious Skin Reactions Among Users of Eslicarbazepine Acetate
The reason for this study is to understand if people with certain genes are predisposed to develop severe skin reactions after they are administered Eslicarbazepine Acetate.
- Trial name
- NCT02520557
- Testing
- Blood or Saliva
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- Sumitomo Pharma America, Inc.
Caesarean Scar Defect
Effectiveness of Transvaginal Niche Resection Versus Expectant Management in Patients with Secondary Infertility and a Large Uterine Caesarean Scar Defect
The goal of this clinical trial is to evaluate the efficacy and safety of transvaginal niche resection in improving pregnancy outcomes of a large uterine caesarean scar defect (niche) with secondary infertility.
- Trial name
- TVARES (NCT06599671)
- Testing
- Transvaginal niche resection
- Volunteers
- 100 people
- Sponsor
- International Peace Maternity and Child Health Hospital
Keloids
Efficacy 2 Part Study of Identification of Keloid Biomarkers and Effect of QAX576 on Keloid Recurrence
This is a 2-part study. In the first part (Part I, 8 subjects), biopsies will be obtained from the resection site after keloid shaving and two weeks following resection to assess and select biomarkers to determine the biologic…
- Trial name
- NCT00987545
- Testing
- QAX576
- Where
- 4 sites in United States
- Volunteers
- 3 people
- Sponsor
- Novartis Pharmaceuticals
Fissure, Dental, Adhesion
Randomized Clinical Trial of Fissure Sealants Comparing Universal Adhesive With Etch-And-Rinse Adhesive After 24 Month
Objective: This randomized, controlled clinical study aimed to evaluate the performance of one universal adhesive applied with etch-and-rinse or self-etch strategy and one etch-and-rinse adhesive on fissure sealant retention over…
- Trial name
- NCT04837469
- Testing
- fissure sealant application
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Ventricular Tachycardia, Monomorphic, Cardiomyopathies
Stereotactic Radioablation as First-Line Therapy for Scar-Related Ventricular Tachycardia
Ventricular tachycardia (VT) is a dangerous fast heart rhythm originating from scarred areas of the heart muscle, often after a heart attack or in patients with cardiomyopathy.
- Trial name
- START-VT (NCT07618780)
- Testing
- Stereotactic Arrhythmia Radioablation
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Southlake Health
Acne Scars, Acne Scars - Atrophic
Safety and Efficacy Evaluation of the Radiofrequency Therapeutic Device for the Treatment of Atrophic Acne Scars
The objective of this clinical trial is to evaluate the safety and effectiveness of a radiofrequency treatment device for the treatment of atrophic acne scars.
- Conditions
- Acne Scars, Acne Scars - Atrophic, Acne Scar, Acne Scarring
- Trial name
- NCT07620769
- Testing
- Investigational Device with the function deactivated, Investigational Device with the function activated, Control Device
- Where
- 4 sites in China
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- CLASSYS Inc.
Keloid
Epidemiology Study of Keloid
Although keloid is a very common condition; there are no statistics as to its true incidence and prevalence, neither in United States, nor elsewhere in the world.
- Trial name
- NCT01423383
- Where
- United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Tirgan, Michael H., M.D.
Ventricular Tachycardia, Ischemic Cardiomyopathy
Ablation-Index Guided Scar-Mediated Ventricular Tachycardia Ablation in Patients With Ischemic Cardiomyopathy
Over the last decade, radiofrequency catheter ablation (RFCA) has become an established treatment for ventricular arrhythmias (VA).
- Trial name
- AIM-VT (NCT06138873)
- Testing
- Ablation-index guided ventricular tachycardia ablation, Ventricular tachycardia ablation with no AI-guidance
- Where
- 5 sites in United States
- Volunteers
- 100 people
- Sponsor
- Rush University Medical Center
Burns
Study With an Autologous Dermo-epidermal Skin Substitute for the Treatment of Burns in Children
This phase IIb trial aims to evaluate the efficacy and safety of EHSG-KF (synonym denovoSkin) in comparison to meshed STSG in children with partial deep dermal and full thickness burns.
- Trial name
- NCT03229564
- Testing
- EHSG-KF, STSG
- Where
- 4 sites in Italy, Netherlands and 1 more
- Volunteers
- 12 people
- Sponsor
- CUTISS AG
Hypertrophic Scar
Hypertrophic Scar Prevention by Novel Topical Gel Application
Researchers are trying to find out more about the side effects of topical (applied to the skin) Pentamidine, to determine if it is safe for use in people.
- Trial name
- NCT03403621
- Testing
- Pentamidine Isethionate
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Mayo Clinic
Dental Implant Failed, Dental Prosthesis Failure
Peri-implant Tissues in BLX® Implants
This is a randomized triple-blind clinical trial to evaluate the behavior of peri-implant tissues (bone and soft tissues) in BLX implants loaded early or delayed and with different surgical milling protocols.
- Trial name
- BLX (NCT03720236)
- Testing
- Implant bed preparation protocol, Implant loading
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Skin Wound, Scar, Hypertrophic
Umbilical Cord Stem Cells for Skin Grafts in Donor Site Wounds
The goal of this clinical trial is to evaluate the safety and effectiveness of human umbilical cord mesenchymal stem cell (hUCMSC) therapy in patients undergoing medium-thickness skin grafts for donor site wounds.
- Trial name
- NCT05984628
- Testing
- human umbilical cord mesenchymal stem cells, blank solvent
- Where
- China
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University Union Hospital