Clinical trials: Scar Tissue, open to volunteers
Dyspareunia
Effectiveness of Radiofrequency Combined With Ultrasound for the Treatment of Postpartum Dyspareunia
The objective of this community-based, non-randomized, quasi-experimental study is to assess the effectiveness of BTL EXILIS technology-based on combined radiofrequency and ultrasound-in women of childbearing age from an…
- Trial name
- NCT07504991
- Testing
- Combining radiofrequency and ultrasound. BTL Exilis
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili
Skin Wound Healing After Cesarean Section, Cesarean Section Scar Healing
Tissue-Engineered Construct Based on Amniotic Membrane and Calcium Alginate for Cesarean Section Wound Healing
This clinical trial aims to evaluate the safety and efficacy of an experimental tissue-engineered construct (TEC) based on amniotic membrane and calcium alginate for promoting epithelialization and improving scar quality in…
- Trial name
- NCT07241013
- Testing
- Tissue-engineered construct based on amniotic membrane and calcium alginate (TEC)
- Where
- Kazakhstan
- Volunteers
- 100 people
- Sponsor
- Asfendiyarov Kazakh National Medical University
Scar Conditions and Fibrosis of Skin, Scar Quality Assessment and Safety
Scar Remodeling After Burn Injury Using Allogeneic Adipose-derived Stromal Cells
The present project serves to test whether stem cell therapy offers a new treatment option for the scars of burn survivors. In Denmark, 12.000 people seek medical assistance every year for burn injuries leaving thousands of…
- Conditions
- Scar Conditions and Fibrosis of Skin, Scar Quality Assessment and Safety, Scar Tissue
- Trial name
- ScarASC (NCT07635875)
- Testing
- Allogeneic adipose-Derived Mesenchymal Stromal Cells, Cryostor CS10 + Ringers Lactate
- Where
- Denmark
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cesarean Scar Pregnancy
The Treatment Outcomes of Cesarean Scar Pregnancy
A prospective randomized controlled study evaluating the impact of various treatment modalities for cesarean scar pregnancy on treatment outcomes and pregnancy outcomes
- Trial name
- NCT07608094
- Testing
- different surgical treatment
- Where
- China
- Volunteers
- 82 people
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Caesarean Scar Pregnancy
Surgical Evacuation Versus Methotrexate Injection in Treatment of Caesarean Scar Pregnancy [Clinical Trial ]
The aim of the study is to compare the effectiveness and the complications of Ultrasound guided surgical evacuation versus using combined local and systemic methotrexate injection for management of caesarean scar pregnancy.
- Trial name
- NCT07288307
- Testing
- Surgical evacuation and methotrexate injection
- Volunteers
- 42 people
- Sponsor
- Minia University
Myofascial Release, Deep Friction Massage
Effect of Myofascial Release Versus Deep Friction Massage on Abdominal Recovery and Scar After Cesarean Section
This study was done to compare the effect of myofascial release versus deep friction massage on abdominal recovery and scar after cesarean section.
- Conditions
- Myofascial Release, Deep Friction Massage, Cesarean Section Complications, Scar
- Trial name
- NCT07130747
- Testing
- Myofascial release, Deep friction massage, Routine daily scar care advices
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Cairo University
Burn Scar, Burn Wound
Post-Operative Use of FS2 to Mitigate Scarring in Burn Patients
The goal of this study is to see how an ingredient called kynurenic acid (which we named "FS2") affects scar formation in people with burn injuries that need skin graft surgery.
- Trial name
- NCT06807021
- Testing
- IP1 control cream (Vehicle base), IP2 - 0.5% w/w FS2
- Where
- 2 sites in Canada
- Volunteers
- 70 people
- Sponsor
- Birch BioMed Inc
Corneal Scar
Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Subjects With Corneal Scars
This study will enroll subjects with recently formed corneal scars that resulted from a corneal insult presenting and diagnosed within the past approximately 30 days and not less than approximately 7 days.
- Trial name
- NCT06257355
- Testing
- CSB-001 Ophthalmic Solution 0.1%
- Where
- 7 sites in United States
- Volunteers
- 20 people
- Sponsor
- Claris Biotherapeutics, Inc.
Cesarean Scar Diverticulum
A Randomized Controlled Study of Uterine Incision Diverticulum Repair vs. no Repair During Second/Third Cesarean Section
The goal of this study is to assess the efficacy and safety of uterine incision diverticulum repair during repeat cesarean section.The main questions it aims to answer are: Can this surgical method improve the symptom of…
- Trial name
- NCT06612957
- Testing
- Repair of uterine cicatricial diverticulum
- Volunteers
- 60 people
- Sponsor
- Shanghai First Maternal and Infant Health Hospital affiliated to Tongji University Medical School
Acne Scars, Ablative Fractional CO₂ Laser Therapy
Comparative Real-world Study on Ablative Fractional CO₂ Laser vs PRP With Microneedling for Acne Scar Treatment.
Road traffic accidents (RTAs) remain a major public health concern worldwide and in Bangladesh, contributing significantly to injury, disability, and premature death.
- Conditions
- Acne Scars, Ablative Fractional CO₂ Laser Therapy, Platelet-rich Plasma (PRP)
- Trial name
- NCT07189923
- Testing
- Ablative Fractional CO₂ Laser, Platelet-Rich Plasma (PRP) With Microneedling
- Where
- Bangladesh
- Volunteers
- 116 people
- Sponsor
- Dr. Sirajul Islam Medical College
Facial Scarring, Facial Trauma
Tools for Return of Facial Function
This study will evaluate novel intraoral (inside-the-mouth) splints designed to gently stretch facial tissues that have become tight or scarred following facial trauma, including burn injuries and gunshot wounds.
- Conditions
- Facial Scarring, Facial Trauma, Burn, Orofacial Contracture
- Trial name
- NCT07825844
- Testing
- Intraoral Stretching Splints
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Cesarean Scar Defect
Impact of a Bladder Flap on Cesarean Scar Niche Development
The goal of this trial is to examine if the completion or omission of a bladder flap impacts the location and formation of cesarean scar niche in women undergoing primary cesarean section.
- Trial name
- B-FIND (NCT07634679)
- Testing
- Bladder flap formation
- Where
- 2 sites in United States
- Volunteers
- 338 people
- Sponsor
- Montefiore Medical Center
Keloids
Comparison Of Effectiveness Of Intralesional Injectioms Of 5 Flourouracil Alone Verses Its Cpmbination With Cryotherapy In The Treatment Of Keloids
The goal of this clinical trial is to learn how well intralesional 5 fluorouracil with cryotherapy works to treat keloids as compared to intralesional 5 fluorouracil alone on keloids.
- Trial name
- NCT07531056
- Testing
- Cryotherapy will be done followed by intralesional injection of 5-fluorouracil, Intralesional 5-fluorouracil
- Where
- Pakistan
- Volunteers
- 88 people
- Sponsor
- Combined Military Hospital (CMH) institute of Medical Sciences Bahawalpur Pakistan
Isthmocele, Cesarean Scar Defect
Clinical Impact of Uterine Repair During Cesarean Section With Barbed Suture on the Incidence of Isthmocele
Pregnant women, irrespective of their pregnancy risk, who undergo a cesarean section for any reason will be randomized to one of two suturing techniques: conventional suture or barbed suture for uterine repair after the cesarean…
- Conditions
- Isthmocele, Cesarean Scar Defect, Pelvic Pain, Spotting
- Trial name
- CESARIS (NCT06691750)
- Testing
- Barbed suture, Conventional smooth suture
- Where
- Spain
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Scar
Tissue-engineered Skin Graft Repair of Autologous Scar Dermal Scaffolds
Hypertrophic scar is an inevitable outcome of wound repair. It affects the appearance and some scar contracture often leads to joint dysfunction.Patients have low quality of life, long treatment cycle, heavy social burden and…
- Trial name
- NCT04389164
- Testing
- Tissue-engineered skin grafts of autologous scar dermal scaffolds
- Where
- China
- Volunteers
- 226 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Cesarean Scar Pregnancy
Effect of Methotrexate on Blood Loss During Laparoscopic Management of CS Scar Pregnancy
Effect of Preoperative Methotrexate on Intraoperative Blood Loss and Surgical Outcomes During Laparoscopic Management of Cesarean Scar Pregnancy: A Prospective Cohort Study.
- Trial name
- CSEP (NCT07886216)
- Volunteers
- 42 people
- Sponsor
- Assiut University
Cleft Lip, Cleft Lip Scar
Cleft Lip Scarring After Botox
This study is investigating whether botulinum toxin type A (Botox) can improve scar appearance after cleft lip repair surgery. Cleft lip repair is commonly performed during infancy, but visible scarring can occur as the incision…
- Trial name
- CLSAB (NCT07880860)
- Testing
- Botulinum Toxin Type A (BOTOX) Injection, Normal Saline
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Children's National Research Institute
Surgical Scar, Postoperative Scar
Impact of Perioperative Antibiotic Use on Surgical Scarring
This retrospective observational cohort study will evaluate whether perioperative antibiotic use is associated with long-term surgical scar outcomes.
- Trial name
- PASS (NCT07741591)
- Testing
- Perioperative Antibiotic Exposure
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Defect
Comparison of the Therapeutic Effects of VR and VR + Metformin in the Treatment of Cesarean Section Scar Defect
Cesarean section scar defect (CSD) is a novel recognized cause of postmenstrual abnormal uterine bleeding in women. No clinical guidelines have been issued for the management of CSD.
- Trial name
- NCT05205317
- Testing
- Metformin Hydrochloride Sustained-release Tablets, Vaginal repair
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Ventricular Tachycardia (VT), Ischemic Cardiomyopathy
Targeted Ablation to Isolate Scar Channels Causing Ventricular Tachycardia
The goal of this study is to map conducting channels within scar that cause ventricular tachycardia (VT) in patients with scar in their hearts in order to block these channels from causing VT with targeted radiofrequency ablation…
- Conditions
- Ventricular Tachycardia (VT), Ischemic Cardiomyopathy, Nonischemic Cardiomyopathy
- Trial name
- NCT07814079
- Testing
- Selective Substrate Isolation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- New York Medical College