Clinical trials: Scarred Uterus
Uterine Caesarean Scar Defect
Enhanced Reproductive Efficiency: Shorter Time to Pregnancy After Hysteroscopic-Assisted Novel Transvaginal Repair
To investigate whether a novel hysteroscopic-assisted transvaginal repair technique results in a shorter time to pregnancy and superior fertility outcomes compared to traditional transvaginal repair.
- Trial name
- NCT07169435
- Where
- China
- Volunteers
- 120 people
- Sponsor
- International Peace Maternity and Child Health Hospital
Recurrent Miscarriage
3D Ultrasound to Assess in Recurrent Miscarriage
This observational study aims to compare the prevalence of acquired abnormalities of the uterus (fibroids, polyps, intrauterine adhesions, adenomyosis) in women who have recurrent miscarriages with the fertile population.
- Trial name
- 3D-ARM (NCT06164015)
- Testing
- 3D Ultrasound scan with power Doppler angiography
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University Hospitals of Derby and Burton NHS Foundation Trust
Cesarean Section, Uterine Scar Deficiency
Impact of Double-layer Versus Single-layer Uterine Closure Suture in Cesarean Section on the Development of Postoperative Uterine Scar Deficiency
In recent decades, the rate of cesarean section delivery has steadily increased worldwide ranging at 30% of deliveries, thus long-term risks after cesarean section need to be evaluated.
- Conditions
- Cesarean Section, Uterine Scar Deficiency, Myometrial Thickness, Single-layer Continuous Uterotomy Suture
- Trial name
- NCT03039803
- Testing
- uterine closure during cesarean section
- Where
- Austria
- Volunteers
- 200 people
- Sponsor
- Medical University of Vienna
Cesarean Scar Defects, Cesarean Section Complications
Diagnostic Accuracy of Saline Sonohystrography vs. 3D Transvaginal Ultrasound for Cesarean Scar Defect Assessment
To compare accuracy of three dimensional transvaginal ultrasound versus the "gold standard" saline infused sonography for assessing the characteristics, frequency and appearance of caesarean scar defects in symptomatic patients…
- Conditions
- Cesarean Scar Defects, Cesarean Section Complications, Uterine Scar Dehiscence, Vaginal Birth After Cesarean
- Trial name
- NCT05996926
- Testing
- Three-Dimensional Transvaginal Ultrasound (3D TVS), Saline-Infused Sonography (Sonohystrography)
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Cairo University
Cesarean Scar Defect (Isthmococele)
Incision-Parallel Double-Layer Non-Locking Versus Single-Layer Locked Uterine Closure After Primary Caesarean Delivery: A Randomized Controlled Trial
This randomized controlled trial was conducted to compare two uterine closure techniques in women undergoing primary cesarean delivery.
- Trial name
- NCT07841028
- Testing
- Single-Layer Locked Uterine Closure, Double-Layer Incision-Parallel Nonlocking Uterine Closure
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Onur Karaaslan
Infertility, Polyp Uterus
HYALOBARRIER® GEL ENDO Versus no HYALOBARRIER® GEL ENDO Following Operative Hysteroscopy for Improving Reproductive Outcome in Women With Intrauterine Pathology Wishing to Become Pregnant
To compare the costs and effects of HYALOBARRIER® GEL ENDO versus no HYALOBARRIER® GEL ENDO for increasing the chance of conception leading to live birth measured at 30 weeks after randomization in women wishing to become…
- Conditions
- Infertility, Polyp Uterus, Myoma;Uterus, Adhesion
- Trial name
- AGNOHSTIC (NCT03880435)
- Testing
- Hyalobarrier® gel endo
- Where
- Belgium
- Volunteers
- 419 people
- Sponsor
- University Hospital, Ghent
Induction of Abortion, Scarred Uterus
Laminaria Japonicum Followed by Misoprostol Versus Misoprostol Alone for Mid-Trimester Abortion Induction in Scarred Uterus
The goal of this clinical trial is to compare the induction-to-abortion time interval between women receiving Laminaria tent followed by misoprostol and those receiving misoprostol alone for mid-trimester abortion induction in…
- Trial name
- Obstetrics (NCT07465016)
- Testing
- Misoprostol ( Cytotec) 200 microgram a tablet, Laminaria Tent
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Pavly Maged Jimmy Fouad
Infertility, Abnormal Uterine Bleeding (AUB)
Evaluation of the Uterine Cavity After Operative Hysteroscopy
This study will focus on evaluation of the uterine cavity after operative hysteroscopy using three dimensional transvaginal ultrasonography and office hysteroscopy to detect and residual or recurrent abnormalities or intrauterine…
- Conditions
- Infertility, Abnormal Uterine Bleeding (AUB), Intrauterine Adhesion, Submucous Leiomyoma of Uterus
- Trial name
- NCT06924437
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Cesarean Section Complications, Abnormal Uterine Bleeding
Combined Hystroscopic and Laparoscopic Repair of CS Scar Disorder
Combined hystroscopic and laparoscopic repair of symptomatic uterine Niche as new technique to maximize resolution of symptoms after niche repair with concomitant increase in RMT
- Trial name
- NCT07183501
- Testing
- Combined hystroscopic and laparoscopic repair
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Cesarean Section; Dehiscence, Uterine Bleeding
Impact of Single- Versus Double-layer Hysterotomy Closure on Cesarean Niche Development: a Randomized Controlled Trial
The objective of this randomized monocentric study is to assess potential variations in the incidence and severity of isthmocele morbidity among women undergoing cesarean section with either single or double-layer closure of the…
- Conditions
- Cesarean Section; Dehiscence, Uterine Bleeding, Uterus; Scar, Uterus Abnormal
- Trial name
- NCT06308172
- Testing
- Hysterotomy closure
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Cesarean Section Complications
Vasopressin vs. Uterine Artery Clamping for Laparoscopic Cesarean Scar Niche Repair
This study evaluates two methods for controlling intraoperative bleeding during laparoscopic surgery to repair a cesarean scar niche (CSN).
- Trial name
- NCT07446933
- Testing
- Vasopressin Group, Bulldog Clamping Group, Standard of Care
- Where
- Saudi Arabia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Scarred Uterus
Planned Mode of Delivery After Caesarean: a Comparative Prospective National Population-based Cohort Study
In women with one previous caesarean, the choice of mode of delivery is determined by a shared decision-making process between the women and the obstetrician, with the two options being a trial of labour after caesarean (TOLAC)…
- Trial name
- CICAMODA (NCT05439733)
- Testing
- Questionnaire completion
- Where
- France
- Volunteers
- 16,764 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Infertility, Asherman's Syndrome
Platelet-rich Plasma (PRP) for Endometrial Regeneration and Repair
Patients with intrauterine adhesions (Asherman's Syndrome) and persistent thin endometrial lining in in vitro fertilization (IVF) treatment programs, particularly those resistant to standard therapies, present a significant…
- Trial name
- PRP-E (NCT02825849)
- Testing
- Intrauterine infusion of platelet rich plasma
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Scar; Previous Cesarean Section
Assessing the Stability of Uterine Scar Tissue in Women With Previous History of Caesarean Section Using Multimodal Analyses of the Lower Uterine Segment Including Quantitative Sonography
This prospective, clinical, observational trial compares the measured value with quantitative ultrasonic (preoperatively) Elastic modulus E (kPA) with the measured value with quantitative ultrasonic Elastic modulus E (kPA) in…
- Trial name
- QUANTUSLUS (NCT02827591)
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Caesarean Scar Pregnancy
UACE Followed by Uterine Suction Curettage for the Treatment of Caesarean Scar Pregnancy
The purpose of this study is to determine whether UACE(uterine artery chemo-embolization) followed by suction curettage under the guidance of ultrasonography or hysteroscopy can decrease complications in the treatment of…
- Trial name
- UACECSP (NCT02357095)
- Testing
- monitoring
- Volunteers
- 144 people
- Sponsor
- Maternal and Child Health Hospital of Hubei Province
Assessment of Uterine Healing
Preliminary Study of Uterine Healing After Caesarean Section: CLInico-ECHOgraphic and Anatomopathologic COrrelation
Caesarean section is one of the most common surgical procedures. The multiplication of uterine scars leads to an increase in complications and in particular those related to poor healing such as isthmocele or uterine rupture.
- Trial name
- COCLIECHO (NCT05785559)
- Testing
- uterine biopsies
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sliding Sign, Vesicouterin Thickness
Vesico-uterin Thickness and Sliding Sign in Term Pregnancies
In this study, our aim was to evaluate the relationship of the bladder to the uterus including vesicouterin thickness and sliding sign in term pregnancies with at least one previous cesarean section and compare to controls.
- Conditions
- Sliding Sign, Vesicouterin Thickness, Term Pregnancy, Adhesion; Bladder
- Trial name
- sliding sign (NCT07523698)
- Testing
- ultrasound evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Adana City Training and Research Hospital
Cesarean Scar Diverticulum
A Randomized Controlled Study of Uterine Incision Diverticulum Repair vs. no Repair During Second/Third Cesarean Section
The goal of this study is to assess the efficacy and safety of uterine incision diverticulum repair during repeat cesarean section.The main questions it aims to answer are: Can this surgical method improve the symptom of…
- Trial name
- NCT06612957
- Testing
- Repair of uterine cicatricial diverticulum
- Volunteers
- 60 people
- Sponsor
- Shanghai First Maternal and Infant Health Hospital affiliated to Tongji University Medical School
Uterine Scar
Safety of Umbilical Cord Mesenchymal Stem Cell Local Intramuscular Injection for Treatment of Uterine Scars
The purpose of this study is to evaluate the safety of umbilical cord mesenchymal stem cell local intramuscular injection for treatment of uterine scars by a prospective, single-center, open, and single-arm clinical trial.
- Trial name
- NCT03181087
- Testing
- Umbilical cord MSCs
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Maternal and Child Health Hospital of Foshan
Termination of Early Pregnancy in Scarred Uterus
Termination of Early Pregnancy in Scarred Uterus With Lletrozole and Misoprostol Compared to Misoprostol Alone
Termination of early pregnancy in scarred uterus with letrozole and misoprostol compared to Misoprostol alone
- Trial name
- NCT05067309
- Testing
- Letrozole 2.5mg
- Where
- 2 sites in Egypt
- Volunteers
- 1 people
- Sponsor
- Ahmed Elsayed Aref