Clinical trials: Scarred Uterus
Uterine Scar From Previous Cesarean Delivery (Diagnosis)
Uterine Niche After Cesarean Section
In the past decade several articles have described a defect that can be seen on ultrasound at the site of cesarean delivery scar, known as a 'niche' .An incompletely healed scar is a long-term complication of cesarean delivery…
- Trial name
- AMSRM (NCT03787381)
- Testing
- Ultrasound
- Where
- Israel
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Quality of Life, Sexual Activity
Quality of Life and Sexual Function of Vaginal Operation in The Treatment Of Previous Cesarean Scar Defect
The aim of this study is to further demonstrate the safety , validity and quality of (sexual)life of vaginal operation for previous cesarean scar defect resection.
- Trial name
- PCSD (NCT01978067)
- Testing
- transvaginal resection of Uterine Scar
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shu-Qin Chen
Uterus; Scar
Isthmocele Development Due to Primary Cesarean Section at The Latent or Active Phase
The importance of isthmocele development due to primary cesarean section at the latent or active phase of labour
- Trial name
- Isthmocele (NCT04891042)
- Where
- Turkey (Türkiye)
- Volunteers
- 320 people
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Caesarean Scar Defect
Effectiveness of Transvaginal Niche Resection Versus Expectant Management in Patients with Secondary Infertility and a Large Uterine Caesarean Scar Defect
The goal of this clinical trial is to evaluate the efficacy and safety of transvaginal niche resection in improving pregnancy outcomes of a large uterine caesarean scar defect (niche) with secondary infertility.
- Trial name
- TVARES (NCT06599671)
- Testing
- Transvaginal niche resection
- Volunteers
- 100 people
- Sponsor
- International Peace Maternity and Child Health Hospital
Adhesion; Uterus, Internal
Use of an Intra Uterine Balloon to Prevent Recurrent Adhesions (REpAIR)
Patients suffering of subfertility as a consequence of intrauterine adhesions could be treated with hysteroscopic adhesiolysis. Adhesion recurrence may occur postoperative.
- Trial name
- NCT03446755
- Testing
- intra uterine Cook balloon
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- University Hospital, Ghent
Twin; Complicating Pregnancy, Advanced Maternal Age Pregnancy
Birth Cohort Study of China Medical University
The CMUBCS is a birth cohort study located in Shenyang, China. Its initial aim is to facilitate research on understanding the interplay between genes and environmental factors on disease etiology.
- Conditions
- Twin; Complicating Pregnancy, Advanced Maternal Age Pregnancy, Scarred Uterus, Overweight and Obesity
- Trial name
- NCT03561766
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Infertility Due to Nonimplantation, Infertility Secondary
Inflammation Markers in Fluid Aspirate From a Scarred Uterine vs. a Normal Uterine Cavity
A prospective study that will take place in the hydrosonography clinic, comparing patients with an intact uterus to those who had a caesarean section.
- Conditions
- Infertility Due to Nonimplantation, Infertility Secondary, Cesarean Section Complications
- Trial name
- NCT06322498
- Testing
- Uterine lavage
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Scarred Uterus
Abnormal Placenta Plant Disease Early Diagnosis and Individualized Treatment Research
As the "two-child" policy implementation, caesarean women's clinical pregnancy is a huge problem again, Especially the placenta planting abnormal disease is a serious threat to the maternal health and life.
- Trial name
- NCT02946749
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Shanghai First Maternity and Infant Hospital
Cesarean Section, Repeated, Cesarean, Uterine Scar Thickness
Impact of Uterine Closure Techniques on the Cesarean Scar Thickness After Repeated Cesarean Section
We compares two techniques of uterine closure on myometrium thickness at the site of uterine scar of women who underwent repeated cesarean section.
- Conditions
- Cesarean Section, Repeated, Cesarean, Uterine Scar Thickness, Cesarean, Residual Myometrial Thickness, Cesarean Section Complications
- Trial name
- NCT03644433
- Testing
- Single layer closure, Double layer closure after resection uterine scar
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Magnetic Resonance Imaging, Ovarian Function
Fertility After Transvaginal Surgery or Uterine Artery Embolization Combined With Uterine Curettage in Patients With Cesarean Scar Pregnancy
To investigate the fertility in patients after treatment by transvaginal surgery or uterine artery embolization combined with uterine curettage
- Conditions
- Magnetic Resonance Imaging, Ovarian Function, Menstruation
- Trial name
- NCT02933190
- Testing
- transvaginal surgery；UAE and D&C
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
Myoma;Uterus, Adhesion; Uterus, Internal
Incidence of Intrauterine Adhesions After Myomectomy With Intrauterine Anti-Adhesion Gel
This prospective randomized study aims to evaluate whether the application of an intrauterine anti-adhesion gel reduces the incidence of intrauterine adhesions (IUAs) following robotic-assisted laparoscopic myomectomy.
- Trial name
- NCT07280286
- Testing
- Women will receive the application of an anti-adhesion gel at the end of the myomectomy procedure
- Volunteers
- 62 people
- Sponsor
- Federico II University
Adhesions Pelvic, Adhesion; Uterus
Prediction of Vesicouterine Adhesions by Transvaginal Sonographic Sliding Sign Technique: a Validation Study
The aim of this study is to evaluate the predictive value of the real-time dynamic TVS sliding sign for vesicouterine pouch adhesions in women and to test the inter- and intraobserver agreement of this new technique.
- Conditions
- Adhesions Pelvic, Adhesion; Uterus, Adhesion; Bladder
- Trial name
- NCT05862155
- Where
- Netherlands
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Cesarean Section Complications, Scar Niche
A Two-Layered Simple Interrupted Myometrial Suturing Reduces Uterine Niche Formation After Primary Cesarean Section
The purpose of the study is to determine whether two-layered simple interrupted myometrial suturing is superior to double-layered continuous suturing for the prevention of uterine niche formation after primary cesarean section.
- Conditions
- Cesarean Section Complications, Scar Niche, Myometrial Remodeling, Suture Techniques
- Trial name
- NCT07229222
- Testing
- Primary Cesarean Section with two-layered simple interrupted suturing of the myometrium, Primary Cesarean Section with double-layered continuous suturing of the myometrium, Saline-infusion Sonohysterography
- Where
- Egypt
- Volunteers
- 380 people
- Sponsor
- Benha University
Uterine Scar, Cesarean Section Complications
Single or Double-layer Uterine Closure Techniques
There are different surgical techniques of uterine closure during cesarean. A growing data has suggested that the closure technique has an effect on uterine scar healing.
- Conditions
- Uterine Scar, Cesarean Section Complications, Cesarean Section; Dehiscence
- Trial name
- NCT03629028
- Testing
- Residual myometrium thickness, Niche Presence, Adjacent myometrium thickness
- Where
- Turkey (Türkiye)
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- Safak Baran Yilmaz
Cesarean Section Complications
Surgical Management of Cesarean Scar Ectopic Pregnancy: Hysteroscopy & Laparoscopy Outcomes
The study investigates the feasibility, safety, and outcomes of a simultaneous surgical approach for cesarean scar ectopic pregnancy (CSEP). CSEP is a prevalent and serious form of ectopic pregnancy requiring swift intervention.
- Trial name
- NCT07095647
- Testing
- Hysteroscopy
- Where
- Egypt
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Benha University
Placenta Accreta, Third Trimester, Uterine Scar Dehiscence
Ultrasound Model to Help Differentiate Between Placenta Accreta Spectrum and Uterine Dehiscence in 3rd Trimester Pregnancies
By using 2d Ultrasound on 3rd trimester pregnant women, a model is made to help differentiate between placenta accreta spectrum and uterine scar dehiscence before operative action to help prepare multi-disciplinary steps if needed
- Trial name
- NCT07236060
- Testing
- 2D ultrasound doppler
- Volunteers
- 50 people
- Sponsor
- Assiut University
Intrauterine Adhesions
Seprafilm Slurry in the Prevention of Uterine Scarring in Patients Undergoing Hysteroscopic Myomectomy
Seprafilm is an FDA-approved temporary bioresorbable barrier that physically separates opposing tissue surfaces. The physical presence of the membrane separates adhesiogenic tissue while the normal tissue repair process takes…
- Trial name
- Seprafilm (NCT01632202)
- Testing
- Seprafilm, Sterile Saline Solution
- Where
- 2 sites in United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Cesarean Section; Dehiscence
Mri in Evaluation of Cesarean Section Scar Niche
To evaluate cesarean section scar and the lower uterine segment in non pregnant woman by MRI to : 1. Assess the clinical symptoms like postmenstrual spotting or prolonged menstrual bleeding, dysmenorrhea, chronic pelvic pain and…
- Trial name
- NCT03911622
- Testing
- MRI
- Volunteers
- 30 people
- Sponsor
- Assiut University
Scar; Previous Cesarean Section, Complications; Cesarean Section, Wound, Dehiscence
Optimization of the Healing Process of the Uterine Scar Tissue After Re-cesarean Section
This prospective, controlled, clinical, intervention study measures the number of uterine Cesarean section scars and median myometrial thickness of women who underwent two Cesarean sections six to nine months after their last…
- Trial name
- OPSTAR (NCT02703519)
- Testing
- resection of uterine scar tissue
- Where
- 2 sites in Germany
- Volunteers
- 116 people
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Transvaginal Ultrasound, Caesarean Section
Transvaginal Ultrasound Assessment of Caesarean Section Uterine Scar Closed by Single Versus Double Layer
This study aimed to evaluate uterine scar thickness and integrity using transvaginal ultrasonography in women randomly assigned to single versus double-layer closure of the uterine incision, with a comparison between the two…
- Conditions
- Transvaginal Ultrasound, Caesarean Section, Uterine Scar, Single Layer
- Trial name
- NCT07074522
- Testing
- Single-layer closure, Double-layer closure
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University