Clinical trials: Scarred Uterus
Cesarean Scar Pregnancy, Menstruation
Outcome After MTX & Transvaginal Surgery or UAE & Uterine Curettage in Patients With Cesarean Scar Pregnancy
Cesarean scar pregnancy (CSP)is one of the more serious complications of pregnancies that occur after a prior cesarean delivery. No clinical guidelines have been issued for the management of CSP.
- Trial name
- NCT03218059
- Testing
- Methotrexate Combined With Transvaginal Surgery
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
Uterine Scar, Cesarean Section Complications
Single or Double-layer Uterine Closure Techniques
There are different surgical techniques of uterine closure during cesarean. A growing data has suggested that the closure technique has an effect on uterine scar healing.
- Conditions
- Uterine Scar, Cesarean Section Complications, Cesarean Section; Dehiscence
- Trial name
- NCT03629028
- Testing
- Residual myometrium thickness, Niche Presence, Adjacent myometrium thickness
- Where
- Turkey (Türkiye)
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- Safak Baran Yilmaz
Cesarean Section, Repeated, Cesarean, Uterine Scar Thickness
Evaluation of Cesarean Scar After Three Different Uterine Closure Technis
The study compares three techniques of uterine closure on myometrium thickness at the site of uterine scar of women who underwent repeated cesarean section.
- Conditions
- Cesarean Section, Repeated, Cesarean, Uterine Scar Thickness, Cesarean, Residual Myometrial Thickness
- Trial name
- NCT03915847
- Testing
- Single layer closure, Double layer closure, Doble layer closure with trimming
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Caesarean Scar Defect
Effectiveness of Transvaginal Niche Resection Versus Expectant Management in Patients with Secondary Infertility and a Large Uterine Caesarean Scar Defect
The goal of this clinical trial is to evaluate the efficacy and safety of transvaginal niche resection in improving pregnancy outcomes of a large uterine caesarean scar defect (niche) with secondary infertility.
- Trial name
- TVARES (NCT06599671)
- Testing
- Transvaginal niche resection
- Volunteers
- 100 people
- Sponsor
- International Peace Maternity and Child Health Hospital
Scar Niche, Abnormal Uterine Bleeding
Sublingual Misoprostol Versus No Cervical Priming Before Hysteroscopic Resection of Symptomatic Uterine Niches
The purpose of the study is to evaluated whether preoperative sublingual misoprostol can enhance the effectiveness and safety of niche resection in patients with symptomatic uterine niche.
- Conditions
- Scar Niche, Abnormal Uterine Bleeding, Cesarean Section Complications
- Trial name
- NCT07271056
- Testing
- Misoprostol 200mcg Tab, Hysteroscopic resection of uterine niche, Saline-infusion Sonohysterography
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Benha University
Uterine Scar
Assessment of Single and Double Layer Suturation of Lower Segment Uterine Incision by USG After C/S
After 6 months of cesarean delivery, the investigators will compare uterine incision scar defects of single and double layer suturation of uterine incision by transvaginal ultrasonography.
- Trial name
- NCT03676907
- Testing
- double layer suturation technique
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Gazi University
Chronic Endometritis, Uterus; Scar
Fertility Restoration Using Autologous Mesenchymal Stem Cells
Treatment of the patients with scarring and adhesions in the uterus resulting from caesarean section or chronic inflammation in the mucosa of the uterus and fallopian tubes and preventing the occurrence of these effects in the…
- Conditions
- Chronic Endometritis, Uterus; Scar, Uterine Synechiae, Fallopian Tube Obstruction
- Trial name
- NCT04432467
- Testing
- Autologous mesenchymal stem cells, standard treatment
- Where
- Belarus
- Volunteers
- 10 people
- Sponsor
- Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus
Isthmocele, Cesarean Scar Diverticula
Comparing Decidual Inclusion vs. Exclusion in Uterine Suture Techniques During Cesarean Section to Improve Scar Thickness and Reduce Isthmocele Risk in Primiparous Women
This study compares two ways of closing the uterus during cesarean delivery. In one group, the decidual layer near the uterine cavity is included in the suture. In the other group, this layer is left out.
- Trial name
- DISSUC (NCT07608874)
- Testing
- Single-Layered Non-Locked Closure with Decidual Inclusion, Single-Layered Non-Locked Closure with Decidual Sparing
- Where
- Switzerland
- Volunteers
- 374 people
- Sponsor
- Kantonsspital Baden
Placenta Accreta
Comparison Between the Role of Transabdominal Ultrasound Versus Transvaginal Ultrasound in Evaluation of Placental Invasion in Cases of Placenta Previa Anterior Wall With Previous Uterine Scar
Objective: To compare between the role of Transabdominal ultrasound versus Transvaginal ultrasound in evaluation of placental invasion in cases of placenta previa anterior wall with previous uterine scar applying the unified…
- Trial name
- NCT03437291
- Testing
- Cesarean section, Transabdominal ultrasound, Transvaginal ultrasound
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Transvaginal Ultrasound, Caesarean Section
Transvaginal Ultrasound Assessment of Caesarean Section Uterine Scar Closed by Single Versus Double Layer
This study aimed to evaluate uterine scar thickness and integrity using transvaginal ultrasonography in women randomly assigned to single versus double-layer closure of the uterine incision, with a comparison between the two…
- Conditions
- Transvaginal Ultrasound, Caesarean Section, Uterine Scar, Single Layer
- Trial name
- NCT07074522
- Testing
- Single-layer closure, Double-layer closure
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Uterine Scar
Safety of Umbilical Cord Mesenchymal Stem Cell Local Intramuscular Injection for Treatment of Uterine Scars
The purpose of this study is to evaluate the safety of umbilical cord mesenchymal stem cell local intramuscular injection for treatment of uterine scars by a prospective, single-center, open, and single-arm clinical trial.
- Trial name
- NCT03181087
- Testing
- Umbilical cord MSCs
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Maternal and Child Health Hospital of Foshan
Induction of Abortion, Scarred Uterus
Laminaria Japonicum Followed by Misoprostol Versus Misoprostol Alone for Mid-Trimester Abortion Induction in Scarred Uterus
The goal of this clinical trial is to compare the induction-to-abortion time interval between women receiving Laminaria tent followed by misoprostol and those receiving misoprostol alone for mid-trimester abortion induction in…
- Trial name
- Obstetrics (NCT07465016)
- Testing
- Misoprostol ( Cytotec) 200 microgram a tablet, Laminaria Tent
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Pavly Maged Jimmy Fouad
Cesarean Section; Dehiscence, Cesarean Scar Niche
Effect of Alpha Lipoic Acid on Uterine Scar Healing After Cesarean Section
The aim of this study is to evaluate the efficacy of alpha lipoic acid on uterine scar healing after cesarean section by using saline contrast sonohysterography
- Trial name
- NCT03257514
- Testing
- alpha lipoic acid drug (thioctic acid acid)
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Ain Shams University
Sliding Sign, Vesicouterin Thickness
Vesico-uterin Thickness and Sliding Sign in Term Pregnancies
In this study, our aim was to evaluate the relationship of the bladder to the uterus including vesicouterin thickness and sliding sign in term pregnancies with at least one previous cesarean section and compare to controls.
- Conditions
- Sliding Sign, Vesicouterin Thickness, Term Pregnancy, Adhesion; Bladder
- Trial name
- sliding sign (NCT07523698)
- Testing
- ultrasound evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Adana City Training and Research Hospital
Minor Intra-uterine Abnormalities
The Impact of Treating Minor Uterine Cavity Abnormalities Diagnosed by Office Hysteroscopy in Unselected In Vitro Fertilization (IVF) Cases
This is a comparative, controlled trial to evaluate the impact of treating undetected, asymptomatic, predefined minor uterine cavity abnormalities on the success of IVF treatment.
- Trial name
- NCT00830401
- Testing
- Treatment of predefined abnormality by hysteroscopic surgery, Ofloxacinum/Doxycycline
- Where
- Netherlands
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht