Clinical trials: Scheduled Surgery
Infection Secondary to Surgical Procedure
Effect of Chlorhexidine Gluconate Hair Bath on the Development of Surgical Site Infection and Time to Discharge
One of the most important preventable complications occurring in the postoperative period is surgical site infections. Surgical site infections (SSI) are infections that occur in incisions, organs or organ spaces that occur after…
- Trial name
- NCT06763211
- Testing
- Chlorhexidine Hair Bath
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- HAVVA ÇOŞKUN
Dry Eye Disease
Application of Pulse Electrical Stimulation Around Eye in Dry Eye Disease Patients Scheduled for LASEK Surgery
This study aims to evaluate the efficacy and safety of applying pulse electrical stimulation around eye in dry eye disease patients who are scheduled for LASEK surgery.
- Trial name
- NCT05271422
- Testing
- Real Pulse Electrical Stimulation (NuEyne 01)
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Nu Eyne Co., Ltd.
Staphylococcus Aureus, Bacteremia
Efficacy, Immunogenicity, and Safety of a Single Dose of V710 in Adult Patients Scheduled for Cardiothoracic Surgery (V710-003 AM2)
This study will assess the efficacy of a single dose of V710 vaccine to prevent serious Staphylococcus aureus infections following elective cardiothoracic surgery.
- Conditions
- Staphylococcus Aureus, Bacteremia, Mediastinitis
- Trial name
- NCT00518687
- Testing
- V710
- Volunteers
- 8,031 people
- Sponsor
- Merck Sharp & Dohme LLC
Scheduled Cardiac Surgery, Age Under 85 Years
Administration of Ropivacaine by Bi-laterosternal Multiperforated Catheters Placed Before a Sternotomy for Cardiac Surgery
The sternotomy site is the most painful site after cardiac surgery. Local infiltration of ropivacaine through the multihole catheters in the bilaterosternal position (BLS) after sternotomy significantly reduces pain at rest and…
- Trial name
- Pre-BLS-Sterno (NCT04495504)
- Testing
- Ropivacaine
- Where
- France
- Volunteers
- 32 people
- Sponsor
- University Hospital, Clermont-Ferrand
Full- Thickness Massive RCT (MRCT) of at Least 5 cm in Diameter Including Fatty Infiltration Grade III or IV
InSpace™ System in Comparison to Best Repair of Massive Rotator Cuff Tear.
This is a post-marketing study to further assess the safety and effectiveness of the InSpace™ device implantation in comparison to surgical repair of full thickness Massive Rotator Cuff Tear .
- Trial name
- NCT01890733
- Testing
- Best Repair of torn Rotator Cuff, InSpace™ system
- Where
- Italy
- Volunteers
- 5 people
- Sponsor
- OrthoSpace Ltd.
Scheduled Surgery
Transfusion HeAd NecK Surgery
During elective surgery, the decision to transfuse a patient to correct anemia or an unstable hemodynamic state is often determined on a case by case basis according to personal and hospital transfusion practice.
- Trial name
- THANKS (NCT03910816)
- Where
- France
- Volunteers
- 377 people
- Sponsor
- University Hospital, Montpellier
Anesthesia Morbidity, Child, Only
Impact of Preoperative Fasting on Intraoperative Glycemic Homeostasis and Enhanced Recovery in Children
In 2018, the main societies of anesthesia (European Society Anaesthesiology, European Society Pediatric Anesthesia, and Association des Anesthésistes Réanimateurs Pédiatriques d'Expression Française) changed the current…
- Conditions
- Anesthesia Morbidity, Child, Only, Fasting Hypoglycemia
- Trial name
- GLYNEMCaen (NCT04826627)
- Testing
- glycemia
- Where
- 2 sites in France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Caen
Cerebral Aneurysm Unruptured, Iron Deficiency Anemia
Effect of Preoperative Intravenous Ferric Carboxymaltose for Clipping Surgery
Hypothesis: Correction of preoperative anemia can reduce the need for intra-/postoperative RBC transfusions and can improve surgical outcomes.
- Conditions
- Cerebral Aneurysm Unruptured, Iron Deficiency Anemia, Surgery
- Trial name
- PICASA (NCT04616092)
- Testing
- FEFINJECT
- Volunteers
- 130 people
- Sponsor
- Seoul National University Hospital
Intraocular Pressure
Effects of Dexmedetomidine on Intraocular Pressure During Scheduled Spine Surgeries
The aim of this study is to examine the effects of intraoperative systemic use of dexmedetomidine on the intraocular pressure (IOP) in patients undergoing spine surgeries in a prone position under general anesthesia.
- Trial name
- NCT04628663
- Testing
- Dexmedetomidine, Normal Saline
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Attikon Hospital
Ovarian Cancer
Monoclonal Antibody Therapy in Treating Patients Scheduled for Surgery to Remove Ovarian Cancer
RATIONALE: Monoclonal antibodies can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. Giving monoclonal antibodies in different ways may kill more tumor cells.
- Trial name
- NCT00006099
- Testing
- Monoclonal antibody hu3S193
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Ludwig Institute for Cancer Research
Acquired Antithrombin Deficiency
Phase 3 Study on the Efficacy and Safety of Human Plasma Derived Antithrombin (Atenativ) in Heparin-Resistant Patients Scheduled to Undergo Cardiac Surgery Necessitating Cardiopulmonary Bypass
The primary objective of this study is to evaluate the efficacy of two different doses of Atenativ, versus placebo, in restoring and maintaining heparin responsiveness in adult patients undergoing cardiac surgery necessitating…
- Trial name
- NCT06096116
- Testing
- Human plasma derived antithrombin
- Where
- 27 sites in United States, Austria and 8 more
- Volunteers
- 120 people
- Sponsor
- Octapharma
Anesthesia Education
The Effect of Video Education on Anesthesia Choice
This prospective single-group study aims to evaluate the effect of preoperative artificial intelligence-based video education on anxiety, anesthesia preference, satisfaction, and knowledge level in patients undergoing…
- Trial name
- NCT07246798
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Cardiac Surgery
Ropivacaine Though Laterosternal Catheters After Cardiac Surgery
This is a prospective double-blinded and randomised study involving patients undergoing cardiac surgery with median sternotomy, the effects on postoperative analgesia of a 48-hr continuous infusion of ropivacaine 2 mg.mL-1, at…
- Trial name
- NCT01196767
- Testing
- Ropivacaine (in one arm); catheterization (in both).
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Clermont-Ferrand
Patients With ASA Status I-III Scheduled for Surgery
Intraoperative Air-Test
Although imaging techniques are the reference standard to diagnose alveolar collapse, in the postoperative period and using the peripheral hemoglobin oxygen saturation (SpO2), a non-invasive simple and accurate test (Air-Test)…
- Trial name
- NCT03469648
- Testing
- Air-Test
- Where
- 2 sites in Spain
- Volunteers
- 180 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Thrombocytopenia
Avatrombopag for the Treatment of Thrombocytopenia in Adults Scheduled for a Surgical Procedure
Phase 3b open-label, multicenter study to evaluate the safety and efficacy of avatrombopag in subjects with thrombocytopenia scheduled for operations to critical sites or operations with a high risk of bleeding.
- Trial name
- NCT03326843
- Testing
- Avatrombopag 60 mg
- Where
- 27 sites in United States
- Volunteers
- 4 people
- Sponsor
- Sobi, Inc.
Gynecologic Disease, Endometriosis
Ultrasound Evaluation of the Pelvis in Women with Suspected Endometriosis Scheduled for Laparoscopic Surgery
An international multicenter observation study to evaluate the diagnostic accuracy and predictive value of ultrasound using the IDEA terminology in the detection of deep endometriosis in women scheduled for surgery.
- Conditions
- Gynecologic Disease, Endometriosis, Endometriosis, Rectum, Endometriosis of Colon
- Trial name
- IDEA1 (NCT04171297)
- Testing
- Ultrasound evaluation of DE
- Where
- 3 sites in Australia, Belgium and 1 more
- Volunteers
- 1,866 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
High-risk Nulliparous Pregnancy, Patients Scheduled for Cesarean Section, Surgical Fear, Preoperative Anxiety, and Cortisol Level
The Effect of Mandala Art Therapy on Surgical Fear and the Stress Hormone (Cortisol) in High-risk Pregnant Women Before Cesarean Section.
This randomized controlled study aims to evaluate the effect of mandala art therapy applied before cesarean section on surgical fear and cortisol levels in high-risk pregnant women.
- Trial name
- NCT07691320
- Testing
- Mandala Art Therapy
- Volunteers
- 142 people
- Sponsor
- Inonu University
Colon Cancer
Response to Immunotherapy in MMR-deficient Localized Colon Cancer
The aim of this study is to evaluate the safety and efficacy of neoadjuvant treatment with pembrolizumab before colonic resection in patients with early-stage (I-III) deficient mismatch repair (dMMR) colon cancer (CC).
- Trial name
- RESET-C (NCT05662527)
- Testing
- Pembrolizumab
- Where
- Denmark
- Volunteers
- 85 people
- Sponsor
- Camilla Qvortrup
Anemia, Iron Deficiency
Nutritional Optimization in Anemic Patients Scheduled for Elective Open-Heart Surgery
1. To test the effect and feasibility of culturally relevant SNP program in Anaemic patients scheduled for elective open-heart surgery versus those getting usual preoperative care in a public sector hospital. 2.
- Trial name
- Prehab_Nutri (NCT07801469)
- Testing
- Immune Modulating Formula, Whey Protein, Multivitamins and Iron Supplements
- Volunteers
- 140 people
- Sponsor
- National Institute of Cardiovascular Diseases, Pakistan
Postoperative Pain, Nerve Block
Investigation of the Effects of Serratus Posterior Superior Intercostal Plane Block and Serratus Anterior Plane Block on Perioperative Analgesia Management in Patients Scheduled for Mastectomy
This study aims to evaluate and compare the analgesic efficacy of two ultrasound-guided regional anesthesia techniques, the serratus anterior plane (SAP) block and the serratus posterior superior intercostal plane (SPSIP) block…
- Conditions
- Postoperative Pain, Nerve Block, Mastectomy, Patient Outcome Assessment
- Trial name
- NCT07510269
- Testing
- SAP Block, SPSIP Block
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Uludag University