Clinical trials: Scheduled Surgery
Mechanical Ventilation
RespirAq Humidifier Usability During Invasive Ventilation
This study aims to capture preliminary safety and effectiveness information on a near-final humidifier device design and to provide data for more extensive research, if required.
- Trial name
- NCT04765878
- Testing
- RespirAq Humidification
- Volunteers
- 20 people
- Sponsor
- Auckland University of Technology
Patients Having a Scheduled Abdominal Surgery Procedure
Muscles in Liver Diseases
Cirrhosis is the 11th leading cause of death in the world. The progression to cirrhosis occurs as a result of chronic hepatic injury, related to excessive alcohol consumption, non-alcoholic steatohepatitis, chronic viral…
- Trial name
- UNIVERSE (NCT04758793)
- Testing
- blood samples, biopsy of abdominal paroie
- Volunteers
- 260 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Vocal Cord Dysfunction
Ultrasound Prediction For Vocal Cord Dysfunction In Patients Scheduled For Anterior Cervical Spine Surgeries
Anterior cervical discectomy and fusion (ACDF) is a highly effective and safe method for spinal cord and cervical root decompression.
- Trial name
- NCT04140799
- Testing
- vocal cord ultrasonography
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Lung Neoplasms
Dose-escalation Study of BIBH 1 in Patients With Non-small Cell Lung Cancer Scheduled for Surgical Resection
Study to assess the toxicity, pharmacokinetics, biodistribution and imaging characteristics associated with increasing doses of 131I-BIBH 1, to compare the uptake of 131I-BIBH 1 in tumour to that of normal tissue in patients with…
- Trial name
- NCT02199886
- Testing
- BIBH 1
- Volunteers
- 6 people
- Sponsor
- Boehringer Ingelheim
ASA Class I/II Patients Scheduled for Surgery Under General Anesthesia
Nitrous Oxide - Sevoflurane-Remifentanil Interaction
patients are allocated to one of the two study groups. In both groups a mixture of 60% nitrous oxide and 40% oxygen is administered through a face mask.
- Trial name
- NCT01103193
- Testing
- remifentanil injected, sevoflurane in step up concentration
- Where
- Belgium
- Volunteers
- 4 people
- Sponsor
- University Hospital, Ghent
Oropharyngeal Squamous Cell Carcinoma
Three Schedules of CUE-101 Administered Before Surgery or Definitive Chemoradiation Therapy in HLA-A*0201 Positive Patients With Locally Advanced, HPV16-Positive Oropharyngeal Squamous-Cell Carcinoma
This is a phase 2 trial to assess the safety and tolerability of three schedules of CUE-101 administered in the neoadjuvant phase before standard of care (SOC) therapy to treatment naïve, HLA-A*0201 positive patients with newly…
- Trial name
- NCT04852328
- Testing
- CUE-101
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Washington University School of Medicine
Difficult Intubation, Airway Disease
STOP-Bang Questionnaire: A Predictor of Obstructive Sleep Apnea and Difficult Mask/Intubation?
Difficult airway management remains the leading cause of anaesthesia-related morbidity and mortality. Obstructive sleep apnea syndrome (OSAS) is a warning sign of difficult airway management.
- Trial name
- NCT06247631
- Testing
- STOP BANG
- Where
- Turkey (Türkiye)
- Volunteers
- 125 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
ENT Patients Scheduled for Surgery
Comparison of Telemedicine Evaluation to Standard Evaluation Methods for Pre-Anesthesia Consultation
The purpose of the study is to evaluate different methods of pre-anesthesia consultation, with the aim of improving the day of surgery experience for the patient.
- Trial name
- NCT01240239
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Loma Linda University
Dry Eye Disease
Application of Pulse Electrical Stimulation Around Eye in Dry Eye Disease Patients Scheduled for LASEK Surgery
This study aims to evaluate the efficacy and safety of applying pulse electrical stimulation around eye in dry eye disease patients who are scheduled for LASEK surgery.
- Trial name
- NCT05271422
- Testing
- Real Pulse Electrical Stimulation (NuEyne 01)
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Nu Eyne Co., Ltd.
Severe Obesity Scheduled for Bariatric Surgery
Cardiometabolic Risk Factor Management and Adherence to Antihypertensive Therapy in Patients With Severe Obesity Prior to Bariatric Surgery: a Prospective Longitudinal Cohort Study
Patients with severe obesity frequently exhibit elevated cardiovascular risk. Contributing factors could be inadequate recognition and subsequent management of cardiovascular risk factors, and non-adherence to cardiovascular…
- Trial name
- NCT07441304
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Universität des Saarlandes
Lung Collapse
HFNC for Induction During Bariatric Surgery Patients.
This study aims to compared the effects of high flow nasal during the induction and during the weaning of anesthesia on intraoperative and postoperative oxygenation and postoperative atelectasis in obese patients undergoing…
- Trial name
- NCT03155711
- Testing
- HFNC group, Standard group
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Cerebral Aneurysm Unruptured, Iron Deficiency Anemia
Effect of Preoperative Intravenous Ferric Carboxymaltose for Clipping Surgery
Hypothesis: Correction of preoperative anemia can reduce the need for intra-/postoperative RBC transfusions and can improve surgical outcomes.
- Conditions
- Cerebral Aneurysm Unruptured, Iron Deficiency Anemia, Surgery
- Trial name
- PICASA (NCT04616092)
- Testing
- FEFINJECT
- Volunteers
- 130 people
- Sponsor
- Seoul National University Hospital
Anxiety Postoperative
Impact on Anxiety of a Digital Application for Children Undergoing Scheduled Ambulatory Surgery
The prospect of pediatric surgery is a source of preoperative anxiety for children and their parents. It affects 50% of children waiting for surgery and the causes vary according to age.
- Trial name
- KOALOU (NCT06227663)
- Testing
- KOALOU(®) digital application
- Where
- France
- Volunteers
- 98 people
- Sponsor
- Centre Hospitalier de Valenciennes
Malnutrition
Recording and Evaluating Preoperative Malnutrition in Electively Scheduled Adult Surgical Patients With the GLIM Criteria (GLIM-study)
Data about the prevalence of preoperative malnutrition according to all the five GLIM criteria among the broad range of surgical patients are lacking.
- Trial name
- GLIM (NCT06144411)
- Testing
- prevalence of preoperative malnutrition
- Where
- Netherlands
- Volunteers
- 215 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Myopia, Hyperopia
Creating LASIK Flaps With the LenSx Femtosecond Laser
This will be a prospective, single-center clinical trial of up to 50 eyes of subjects scheduled to undergo LASIK surgery requiring an initial corneal flap. Subjects will be screened for eligibility.
- Trial name
- NCT01556893
- Testing
- LenSx Laser
- Where
- Hungary
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Alcon LenSx, Inc.
Airway Obstruction, Difficult Intubation
A Study of Laryngoscopic Vision With the TotalTrack Device Versus Indirect Laryngoscopy
Assessment of the airway forms part of routine anesthetic practice. However, the predictions referred to intubation or ventilation difficulties are usually inconclusive.
- Trial name
- MULTITOTAL (NCT03208140)
- Where
- 2 sites in Spain
- Volunteers
- 300 people
- Sponsor
- Formacion Internacional para la Docencia e Investigación de la Vía Aérea
Atelectasis
Effects of Spontaneous Breathing Activity on Atelectasis Formation During General Anaesthesia
Atelectasis and redistribution of ventilation towards non-dependent lung zones are a common side effects of general anesthesia. Spontaneous breathing activity (SBA) during mechanical ventilation may avoid or reduce atelectasis…
- Trial name
- SBAFGA (NCT01073917)
- Testing
- Spontaneous Breathing, Pressure Controlled Ventilation, Pressure Support Ventilation
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Technische Universität Dresden
Patient Scheduled for Surgery
Evaluation of Pupillometry as a Predictor of Pain Intensity Upon Withdrawal of Sedation in the Postoperative Period Following Cardiac Surgery: A Prospective Cohort Study
Postoperative pain is a significant issue following surgery, and pain that is either inadequately treated or, conversely, overtreated can increase morbidity.
- Trial name
- PUPREA (NCT07648342)
- Testing
- Pupilometry, VAS
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Hypovolemia
Comparison of Two Gelatine Solutions
The aim of volume replacement is to compensate a reduction in the intravascular volume e.g. during surgery and to counteract hypovolemia in order to maintain hemodynamics and vital functions.
- Trial name
- NCT01515397
- Testing
- Gelofusine balanced, Gelofusine 4%
- Where
- 2 sites in Germany
- Volunteers
- 40 people
- Sponsor
- B. Braun Melsungen AG
Post Operative Pain
Patient Satisfaction and Pain Control Following Reconstructive Vaginal Surgery
The investigators hypothesize that patient controlled analgesia (PCA) provides superior pain relief and patient satisfaction when compared to scheduled intravenous analgesia following vaginal reconstructive surgery.
- Trial name
- NCT01442818
- Testing
- Dilaudid PCA, Dilaudid IV Scheduled
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- TriHealth Inc.