Clinical trials: Scheduled Surgery, open to volunteers
Orthopedic Procedure, Anesthesia
Evaluation of the Impact of Virtual Reality on Sedation Use in Patients Undergoing Regional Anesthesia for Scheduled Orthopedic Surgery
The VIRTUALR study evaluates the effect of virtual reality combined with hypnosis on anxiety in patients undergoing orthopedic surgery under regional anesthesia.
- Conditions
- Orthopedic Procedure, Anesthesia, Sedation
- Trial name
- VIRTUALR (NCT07013695)
- Testing
- Virtual reality headset, Standard Care (in control arm)
- Where
- France
- Volunteers
- 164 people
- Sponsor
- Centre Hospitalier Eure-Seine
Postoperative Pain; Knee Arthroscopy; Acupuncture
Acupuncture for Pain Control After Ambulatory Knee Arthroscopy
Aim of the study: To investigate whether acupuncture with indwelling fixed needles reduces pain and analgesic requirement and foster mobilization in patients after arthroscopic knee surgery (AKS) Design: Prospective pilot…
- Trial name
- AcuK-Scope (NCT04134702)
- Testing
- Acupuncture
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Diabetes Mellitus, Pancreas Transplantation
The Norwegian Pancreas Transplantation (PTx) Study
Several studies have shown acceptable results after Pancreas Transplantation (PTx) by substituting ATG with basiliximab, which is considered to convey a considerably lower number of adverse events.
- Conditions
- Diabetes Mellitus, Pancreas Transplantation, Allograft Rejection, Surgical Complication Nec
- Trial name
- PTx (NCT01957696)
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Oslo University Hospital
Surgical Procedure, Unspecified, Non Small Cell Lung Cancer
Fissios© and Postoperative Complications (FPoC Trial)
Respiratory physiotherapy as part of a pre-operative physical training program may reduce the risk of developing post-operative complications, improving post-operative results and optimizing physical conditions in patients with a…
- Conditions
- Surgical Procedure, Unspecified, Non Small Cell Lung Cancer, Surgery Scheduled, Thoracic Surgery
- Trial name
- FPoC (NCT06732193)
- Testing
- On-site respiratory physiotherapy, Fissios App
- Where
- Spain
- Volunteers
- 560 people
- Sponsor
- Carlos Alfredo Fraile Olivero, MD, PhD.
Patients Scheduled for Elective Lower Extremity Surgery, Ages 18-80
Parasacral Ischial Plane Block in Lower Extremity Surgery
The parasacral ischial plane block is a novel fascial plane approach targeting the sacral plexus. This technique is technically less challenging and eliminates the requirement for direct visualization of the sacral plexus.
- Conditions
- Patients Scheduled for Elective Lower Extremity Surgery, Ages 18-80, ASA I-III, Patients Operated on Under Regional Anesthesia
- Trial name
- NCT07594197
- Testing
- Parasacral Ischial Plan Block, Sacral plexus block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Preoperative Anxiety, Women's Health
Anxiety, Physiological Parameters, Patient Satisfaction and VR in Gynecological Oncology Surgery
Surgical procedures often cause significant anxiety in patients, particularly among women undergoing gynecological oncology surgeries.
- Conditions
- Preoperative Anxiety, Women's Health, Gynecological Cancers, Gynecological Surgery
- Trial name
- NCT07016880
- Testing
- Virtual Reality Relaxation Session
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Hacettepe University
Patient Scheduled for Surgery
Evaluation of Pupillometry as a Predictor of Pain Intensity Upon Withdrawal of Sedation in the Postoperative Period Following Cardiac Surgery: A Prospective Cohort Study
Postoperative pain is a significant issue following surgery, and pain that is either inadequately treated or, conversely, overtreated can increase morbidity.
- Trial name
- PUPREA (NCT07648342)
- Testing
- Pupilometry, VAS
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Postoperative Pain, Nerve Block
Investigation of the Effects of Serratus Posterior Superior Intercostal Plane Block and Serratus Anterior Plane Block on Perioperative Analgesia Management in Patients Scheduled for Mastectomy
This study aims to evaluate and compare the analgesic efficacy of two ultrasound-guided regional anesthesia techniques, the serratus anterior plane (SAP) block and the serratus posterior superior intercostal plane (SPSIP) block…
- Conditions
- Postoperative Pain, Nerve Block, Mastectomy, Patient Outcome Assessment
- Trial name
- NCT07510269
- Testing
- SAP Block, SPSIP Block
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Uludag University
Anesthesia, Dexmedetomidine
Evaluation of the Hemodynamic Effect of Dexmedetomidine in Scheduled Outpatient Surgery
Ambulatory surgery is increasingly used in anesthesia. In case of general anesthesia, it is recommended to use anesthesia molecules with a short half-life and low doses of opiates to ensure a rapid awakening and to prevent nausea…
- Conditions
- Anesthesia, Dexmedetomidine, Hemodynamics, Ambulatory Care
- Trial name
- DEXCOEUR (NCT06082856)
- Testing
- Dexmedetomidine, Sufentanil
- Where
- France
- Volunteers
- 594 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Benign Prostatic Hyperplasia
Preoperative Anxiety and Surgical Fear in Holmium Laser Enucleation of the Prostate and Transurethral Resection of the Prostate Patients With Benign Prostatic Hyperplasia
Benign prostatic hyperplasia (BPH) is a common condition in older men and may cause bothersome lower urinary tract symptoms that can negatively affect quality of life.
- Trial name
- HoLEP and TURP (NCT07663097)
- Testing
- Holmium Laser Enucleation of the Prostate (HoLEP), Transurethral Resection of the Prostate (TURP)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Hitit University
Renal Cell Carcinoma (RCC)
Anlotinib + Benmelstobart vs Surgery for Patients With Localized Renal Cell Carcinoma Scheduled to Undergo Partial Nephrectomy
Evaluation of long-term renal function improvement, surgical safety, as well as efficacy and safety of preoperative anlotinib hydrochloride capsules combined with benmelstobart injection versus surgery in patients with localized…
- Trial name
- ALTER-UC-011 (NCT07627464)
- Testing
- Anlotinib hydrochloride + Benmelstobart + Partial nephrectomy, Partial nephrectomy
- Where
- 14 sites in China
- Volunteers
- 144 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Oropharyngeal Squamous Cell Carcinoma, HPV-mediated Oropharyngeal Squamous Cell Carcinoma
Shortened Course of Radiation Therapy After Trans-oral Robotic Surgery in Patients With HPV-Mediated Oropharyngeal Squamous Cell Carcinoma.
The goal of this study is to evaluate if a shorter course of therapy can improve the quality of life in patients receiving radiation therapy after trans-oral robotic surgery.
- Trial name
- RAD RAPTORS (NCT07044635)
- Testing
- Radiation Therapy
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Utah
Anesthesia, Sedation
The Million Anesthesia Cases Study (MACS) - a Cohort Study of Preoperative Fasting and Perioperative Outcomes
Perioperative fasting has historically been viewed as a low-risk intervention. However, preliminary data indicate that perioperative loss of nutrition and fluids is likely harmful.
- Conditions
- Anesthesia, Sedation, Monitored Anesthesia Care, Procedure
- Trial name
- MACS (NCT07022951)
- Testing
- Preoperative fasting
- Where
- United States
- Volunteers
- 1,200,000 people
- Sponsor
- Massachusetts General Hospital
Anxiety, Pain
Effects of Music on Preoperative Anxiety in Patients With Femoral Fractures Undergoing Surgery
This randomized controlled trial (RCT) investigates the effectiveness of music therapy in reducing preoperative anxiety among elderly patients with femoral fractures.
- Conditions
- Anxiety, Pain, Surgery, Femoral Fractures
- Trial name
- NCT07008482
- Testing
- Music intervention
- Volunteers
- 154 people
- Sponsor
- Azienda Unita Sanitaria Locale di Piacenza
Sleep
Sleep Longitudinal Exploration of the Experience of Patients
Many epidemiological studies report that insomnia is common after fifty years in the general population but also in the post-operative period of surgery.
- Trial name
- SLEEP (NCT06888427)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Thyroid Nodule (Diagnosis)
Safety & Feasibility of Ultrasound-assisted Non-invasive Measurement of Compressibility of the Thyroid Gland in Patients Scheduled for Surgical Removal
The thyroid gland plays an important role in hormone regulation however, it is often prone to nodules. This is common with nodules being found in up to 68% of people in a neck ultrasound, with likelihood increasing with age.
- Trial name
- NCT07102264
- Testing
- CPMX1
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Desaturation, Apnea, Hypoxia
The Effectiveness of Oxygen Reserve Index in Early Detection of Desaturation in Geriatric Patients Scheduled for Oncological Surgery
This prospective observational study aims to evaluate the relationship between the Oxygen Reserve Index (ORI) and tolerable apnea time in geriatric patients undergoing elective oncologic surgery under general anesthesia.
- Conditions
- Desaturation, Apnea, Hypoxia, Oxygen Reserve Index
- Trial name
- NCT07326293
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Ankara City Hospital Bilkent
Loosening, Prosthesis, Hip Arthropathy
Radiographic Stability of Hip Prosthesis Prior to Revision Surgery
The goal of this validation study is to compare the preoperative implant stability, assessed by Implant Movement Analysis (IMA), provocation dual CT scans, with the intraoperative stability evaluation in revision hip arthoplasty.
- Trial name
- MULTICIMA (NCT06924567)
- Testing
- Implant motion provocation CT
- Where
- 6 sites in Denmark, Norway and 1 more
- Volunteers
- 600 people
- Sponsor
- Georgios Tsikandylakis, MD PhD
Frail Elderly Syndrome
The Importance of Anesthesia Method in Fragile Patients
The aim of this study is to comparatively evaluate the effects of different anaesthesia methods (spinal anaesthesia and general anaesthesia) administered to frail elderly patients scheduled for transurethral surgery (e.g.
- Trial name
- NCT07191769
- Testing
- general anaesthesia, regional anaesthesia
- Volunteers
- 180 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Ovarian Cancer
Utility of Adjusting Chemotherapy Dose & Dosing Schedule With the SALVage Weekly Dose-dense Regimen in Patients With Poor Prognostic OVARian Cancers Based on the Tumor Unfavorable Primary Chemosensitivity and Incomplete Debulking Surgery
SALVOVAR will be a pragmatic open-label multicenter randomized phase III trial (ratio 1:1) comparing the efficacy of the salvage weekly dose-dense regimen with those of the continuation of the standard regimen.
- Trial name
- SALVOVAR (NCT06476184)
- Testing
- Carboplatin, Paclitaxel
- Where
- 76 sites in France, Italy and 2 more
- Volunteers
- 250 people
- Sponsor
- ARCAGY/ GINECO GROUP