Clinical trials: Schizophrenia Disorders
Schizophrenia
In-Patient Study In Schizophrenic Patients
This study is a placebo-controlled study to assess the safety and tolerability of a novel antipsychotic medication, (773812) when given to schizophrenic patients for twenty-eight days.
- Trial name
- NCT00197093
- Testing
- SB773812
- Volunteers
- 60 people
- Sponsor
- GlaxoSmithKline
Comparing Hospitalisation Time With Seroquel and Seroquel Prolong
Nis Register Study Comparing Seroquel and Seroquel Prolong
The general aim of this non interventional study is to clarify what are the current clinical treatment practices of Quetiapine Immediate Release and Quetiapine Extended Release.
- Trial name
- NCT00965536
- Where
- Finland
- Volunteers
- 200 people
- Sponsor
- AstraZeneca
Schizophrenia
Peer-led Psycho-education for Schizophrenia
Profession-led psycho-education programs for people with schizophrenia are evidenced to improve patients' knowledge about the illness, mental state and relapse rate.
- Trial name
- NCT03246932
- Testing
- Peer-led psycho-education group, Profession-led psycho-education group, Routine psychiatric care
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 342 people
- Sponsor
- Chinese University of Hong Kong
Affective Disorders, Psychotic
Clinical Validation of the Rating Scale for Psychotic Depression (RAS-PD)
The aim of this study is to develop a scale to measure the severity of depression with psychotic symptoms (psychotic depression).
- Trial name
- NCT01518049
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Søren Dinesen Østergaard
Bipolar Affective Disorder, Schizophrenia Disorders
Medical Phenotyping of NHS General Adult Psychiatry (GAP) Inpatients
This observational study will characterise the general psychiatric and general medical phenotypes of 100 adults, sequentially admitted to NHS General Adult Psychiatry (GAP) "mental health" inpatient wards, providing the first…
- Conditions
- Bipolar Affective Disorder, Schizophrenia Disorders, Depression Disorders, Personality Disorders
- Trial name
- NCT07398365
- Testing
- Questionnaires, rating scales, & review of notes
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University of Edinburgh
Schizophrenia
The Effect of Intranasal Administration of Oxytocin on Empathic Abilities.
Empathy constitutes one prominent ability of social cognition, which represents the human capability of understanding mental state of the other, and responding in sympathetic way.
- Trial name
- 20070766 (NCT00813436)
- Testing
- Oxytocin (also: syntocinon, pitocin)
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shalvata Mental Health Center
Schizophrenia
Compensatory Strategies Applied to Cognitive Impairment in Schizophrenia
The purpose of this study is to determine whether Cognitive Adaptation Training are effective in comparison with conventional treatment, focusing on social functions, symptoms, relapse, re-hospitalisation, and quality of life in…
- Trial name
- CAT-Denmark (NCT01055509)
- Testing
- Cognitive Adaptation Training
- Where
- 3 sites in Denmark
- Volunteers
- 65 people
- Sponsor
- University of Southern Denmark
Schizophrenia
Linagliptin and Mesenchymal Stem Cells: A Pilot Study
The purpose of the present study is to gather pilot data on the effects of linagliptin on the concentration of the long and short forms of SDF1-α (stromal cell-derived factor alpha) in humans, and to demonstrate the feasibility…
- Trial name
- NCT02442817
- Testing
- Linagliptin
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Nevada, Reno
Schizophrenia
SCIT Versus TAR for Outpatients With Schizophrenia
The present work consists of a randomized clinical trial comparing the effectiveness of two interventions based on social cognition training in outpatients with schizophrenia.
- Trial name
- NCT03446703
- Testing
- SCIT, TAR
- Volunteers
- 100 people
- Sponsor
- University of Alcala
Schizophrenia
Long-term Safety of SPD489 When Added to Stable Doses of Antipsychotic Medications in Clinically Stable Adults With Negative Symptoms of Schizophrenia
The primary purpose of this study is to determine if the long-term use of SPD489 (40, 80, 100, 120, 140, and 160mg) administered as a daily morning is safe and tolerable.
- Trial name
- NCT01760993
- Testing
- SPD489
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- Shire
Schizophrenia, Schizoaffective Disorder
Effect of High-Dose B-Complex Vitamins on the Symptoms of Schizophrenia
The purpose of this study is to determine whether individuals with schizophrenia who will take a high dose of the B-vitamins folate, B12 and pyridoxine, may experience improvement in their symptoms.
- Trial name
- NCT00403247
- Testing
- Capsule with folate, Vitamin B12 & pyridoxine
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Nathan Kline Institute for Psychiatric Research
Quality of Life in Schizophrenia
Non-interventional Open Label Study to Investigate the Effect of Quetiapine XR on Patient Satisfaction and Quality of Life in Patients With Schizophrenia
Since subjective well-being and quality of life (QoL) are increasingly being recognized as important treatment outcomes in patients with schizophrenia (Hofer et al., 2004; Becker et al., 2005), the aim of this study is to…
- Trial name
- PASQAL (NCT00934726)
- Volunteers
- 150 people
- Sponsor
- AstraZeneca
Psychosis
Improving Access to Early Psychosis Coordinated Specialty Care
The aim of this study is to evaluate the feasibility of developing an Early Psychosis CSC service delivery model suitable for rural settings in NC.
- Trial name
- NCT04277585
- Testing
- Telehealth
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of North Carolina, Chapel Hill
Relapse Management
Relapse Management Group Psychoeducation Program
This study was planned to be conducted between February and March 2026, with a total of 60 patients diagnosed with schizophrenia who met the inclusion criteria and were followed at the community mental health center in the…
- Trial name
- NCT07327944
- Testing
- Relapse Management Group Psychoeducation Program
- Volunteers
- 60 people
- Sponsor
- Ankara Etlik City Hospital
Schizophrenia, Major Depression
Effect of Specific Anti-Toxoplasmatic Add-on Medication in Toxoplasma Gondii Seropositive Individuals With Schizophrenia or Major Depression
We investigate whether the add-on specific antitoxoplasmatic medication has positive effects in individuals with schizophrenia or major depression seropositive for Toxoplasma gondii (TG) infection.
- Trial name
- NCT00300404
- Testing
- daraprim, pyrimethamine, folinic acid
- Volunteers
- 40 people
- Sponsor
- Zentrum für Integrative Psychiatrie
Schizophrenia
Evaluation of Effectiveness and Safety of Paliperidone ER (Extended-release) Compared With Quetiapine in Patients With Schizophrenia
The purpose of this study is to evaluate the efficacy (effectiveness of drug) and safety of the antipsychotic paliperidone ER compared to another antipsychotic, quetiapine, and to placebo in patients who are acutely ill with…
- Trial name
- NCT00334126
- Volunteers
- 399 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Alcohol Abuse, Alcohol Use Disorder
The Effect of Comorbid Alcohol/Substance Use
Study Design This study was designed as a comparative, cross-sectional case-control study examining the effect of comorbid alcohol and substance use disorder (ASUD) on clinical course and social inclusion among individuals with…
- Conditions
- Alcohol Abuse, Alcohol Use Disorder, Substance Use Disorders, Severe Mental Disorder
- Trial name
- NCT07692984
- Testing
- case (comorbid diagnosis), control
- Where
- Turkey (Türkiye)
- Volunteers
- 297 people
- Sponsor
- Abant Izzet Baysal University
Cognitive Impairment Associated With Schizophrenia (CIAS)
A Study To Evaluate The Safety And Efficacy Of PF-04958242 In Subjects With Cognitive Impairment Associated With Schizophrenia (CIAS)
The purpose of this study is to determine whether PF-04958242 is safe and effective in the treatment of cognitive dysfunction in schizophrenia subjects
- Trial name
- NCT02855411
- Testing
- PF-04958242
- Where
- 16 sites in United States
- Volunteers
- 35 people
- Sponsor
- Biogen
Schizophrenia
Risperidone Treatment in Schizophrenia Patients Who Are Currently Taking Clozapine
This study will determine whether adding the drug risperidone (Risperdal®) is more effective than placebo in treating schizophrenic patients who are taking the drug clozapine.
- Trial name
- NCT00056498
- Testing
- Risperdal
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of Maryland, Baltimore
Schizophrenia
Enhancing Brain Connectivity in Schizophrenia Through Neuromodulation (Study 3)
The aim of the study is to assess the treatment effects of deep active repetitive transcranial magnetic stimulation (rTMS) with H4 coil combined with cognitive training for improving frontal white matter microstructural integrity…
- Trial name
- NCT07772349
- Testing
- Active rTMS, Strong Cognitive Training, Weak Cognitive Training
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- The University of Texas Health Science Center, Houston