Clinical trials: Schizophrenia and Disorders With Psychotic Features
Schizophrenia, Schizoaffective
An Open Trial of Cysteamine Treatment in Schizophrenia
The purpose of this study is to determine the tolerability of the medication cysteamine bitartrate on schizophrenia patients and to evaluate the effect of the medication on the symptoms of schizophrenia.
- Trial name
- NCT01139125
- Testing
- (Cystagon) Cysteamine Bitartrate
- Where
- 2 sites in United States
- Volunteers
- 3 people
- Sponsor
- Augusta University
Schizophrenia
Long-Term Efficacy and Safety of Asenapine Using Olanzapine as a Positive Control (41512)(COMPLETED)(P05784)
Schizophrenia is a brain disease. The primary features of schizophrenia are characterized by Positive symptoms (symptoms that should not be there, inability to think clearly, to distinguish reality from fantasy i.e., hearing…
- Trial name
- NCT00156091
- Testing
- Olanzapine, Asenapine
- Volunteers
- 260 people
- Sponsor
- Organon and Co
Schizophrenia
Safety and Tolerability of Risperidone Implants
A one year, open-label, study to evaluate the safety and tolerability of risperidone implants as a maintenance treatment in patients with schizophrenia
- Trial name
- NCT02773576
- Testing
- Risperidone implant
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Braeburn Pharmaceuticals
Schizophrenia / Schizoaffective Disorder
tACS for Self-Other Boundary in Schizophrenia
This clinical trial investigates whether a non-invasive brain stimulation technique called transcranial alternating current stimulation (tACS) can improve the ability to distinguish between "self" and "others" in patients with…
- Trial name
- NCT07818668
- Testing
- Transcranial Alternating Current Stimulation (tACS)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Chunyan Zhu
Schizophrenia, Psychosis
Aripiprazole Treatment of Prodromal Patients
We hypothesize that symptoms will improve in patients who meet diagnostic criteria for the schizophrenia prodrome when they are prescribed aripiprazole.
- Trial name
- NCT00237874
- Testing
- Aripiprazole
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Yale University
Schizophrenia, Schizoaffective Disorder
Theta Burst Stimulation for Schizophrenia
Purpose and objective Schizophrenia is a chronic debilitating illness with cognitive deficits that cause serious impairment in psychosocial recovery and with few treatments to remediate these deficits.
- Trial name
- NCT03288779
- Testing
- Theta Burst Stimulation
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Duke University
Schizophrenia, Schizoaffective Disorder
Systematic Evaluation of Antiviral Medication in Schizophrenia
The purpose of this study is to examine whether antiviral medication will help improve psychotic symptoms and cognition in individuals early in the course of schizophrenia or schizoaffective disorder who are exposed to herpes…
- Trial name
- SEAMS (NCT00514449)
- Testing
- Valacyclovir
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- Konasale Prasad
Schizophrenia
A Positron-Emission-Tomography (PET) Study to Measure the Blockade of Dopamine Receptors (D2) in Specific Areas of the Brain in Relation to the Plasma Concentrations of Paliperidone Extended Release (ER) and Oral Risperidone in Schizophrenia Patients and Healthy Controls
The primary objective of this study is to compare the effect of two different antipsychotic compounds which are used in the treatment of schizophrenia (paliperidone ER and risperidone) at their target sites in two specific areas…
- Trial name
- NCT00934635
- Testing
- Paliperidone ER, Oral risperidone, PET Scan
- Where
- Germany
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Janssen-Cilag G.m.b.H
Schizophrenia, Bipolar I Disorder
A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Sublingual Asenapine in a Pediatric Population With Schizophrenia or Bipolar I Disorder (P06522 AM1)
This study is an open label, sequential-group, two site, multiple dose escalating study of sublingual administered asenapine in a pediatric population with schizophrenia or bipolar I disorder; in one study cohort (3a)…
- Trial name
- NCT01206517
- Testing
- Asenapine 2.5 mg, Asenapine 5 mg, Asenapine 10 mg
- Volunteers
- 30 people
- Sponsor
- Organon and Co
Auditory Hallucinations in Patients With Schizophrenic Disorders
High Frequency Repetitive Transcranial Magnetic Stimulation (rTMS) in Schizophrenia : a Randomized Controlled Study
Background: Repetitive transcranial magnetic stimulation (rTMS) is a recent therapeutic which has demonstrated its efficacy in the treatment of auditory hallucinations in patients with schizophrenic disorders.
- Trial name
- TMS-Hz (NCT01022489)
- Testing
- Transcranial magnetic stimulation: rTMS
- Where
- France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Caen
Schizophrenia, Bipolar Disorder
Longitudinal Effect of Electroconvulsive Therapy on Schizophrenia and Bipolar Disorder: a MRI Study
For more severe and treatment-resistant cases in schizophrenia and bipolar disorder, electroconvulsive therapy (ECT) is often very effective.
- Trial name
- NCT03651674
- Testing
- ECT treatment, Drug treatment
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Xidian University
Schizophrenia and Related Disorders, Bipolar Disorder
Exercise Therapy in Mental Disorders-study
The study will compare standard high-intensity training with brief high-intensity training in people with schizophrenia-spectrum or bipolar disorder.
- Trial name
- NCT06313918
- Testing
- High intensity training (HIT)
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Haukeland University Hospital
Psychotic Disorders
HCT Effect Among Patients With Psychotic Disorders
Horticulture therapy has been found to have positive effects on individuals with psychotic disorders, promoting social interaction, reducing social isolation, and improving cognitive function.
- Trial name
- HCT (NCT06077279)
- Testing
- Horticultural Therapy Program
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Schizophrenia
Atomoxetine for Treatment of Weight Gain in Olanzapine or Clozapine Patients
The study investigates the use of Atomoxetine in combination with exercise and a diet support group (Weight Watchers)to treat weight gain associated with Olanzapine or clozapine.
- Trial name
- NCT00176436
- Testing
- Diet support group, Group counseling and exercise
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Maryland, Baltimore
Schizophrenia, Schizoaffective Disorder
Injectable Naltrexone Treatment of Alcohol Dependence in Serious Mental Illness (SMI)
The overall goal of this project is to improve the treatment of alcohol dependence in patients with serious mental illness (SMI).
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Alcohol Dependence
- Trial name
- vivitrol (NCT00453609)
- Testing
- long-lasting injectable naltrexone
- Where
- 3 sites in United States
- Volunteers
- 15 people
- Sponsor
- State University of New York - Upstate Medical University
Schizophrenia
Effectiveness of Antipsychotic Combination With Psychosocial Intervention on Outcome of Patients With Schizophrenia
Antipsychotic alone is limit to improve the overall outcome of schizophrenia and has a high discontinue rate.To solve these problems, we provide practical and available psychosocial intervention.
- Trial name
- ACPIOS (NCT00654576)
- Testing
- Chlorpromazine, Sulpiride, Clozapine, Olanzapine, Risperidone, Quetiapine, Aripitrazole, psychosocial intervention
- Where
- China
- Volunteers
- 1,400 people
- Sponsor
- Central South University
Schizoaffective Disorder
Synergy Between Physical Activity and Outdoor Green Environments to Reduce the Intensity of Negative Symptoms in Schizophrenia.
Physical activity appears to be a novel and original adjunctive therapeutic approach in the management of patients with schizophrenia.
- Trial name
- SAPIN (NCT07058389)
- Testing
- 8-week outdoor physical activity program, 8-week indoor physical activity program
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Schizophrenia
Evaluation of Dorsal Visual Stream in Patients With Schizophrenia
Schizophrenia patients in comparing to normal controls show decreased ability to identify objects with decreased level of fragmentation, a task that is associated with magnocellular pathway function.
- Trial name
- NCT01378403
- Where
- Israel
- Volunteers
- 22 people
- Sponsor
- Sheba Medical Center
Hallucinations, Psychoses
Treatment of Hallucinosis/Psychosis in Parkinson's Disease by an Investigational Drug
The primary objective is to demonstrate that the investigational new drug, ACP-103, is well tolerated by, and will not worsen parkinsonism in, patients with Parkinson's disease and psychosis.
- Conditions
- Hallucinations, Psychoses, Parkinson's Disease
- Trial name
- NCT00087542
- Testing
- ACP-103
- Where
- 13 sites in United States
- Volunteers
- 60 people
- Sponsor
- ACADIA Pharmaceuticals Inc.
Auditory Hallucination
The Efficacy of Speech Competition Training on Auditory Hallucination in Schizophrenia
One hundred schizophrenia patients with auditory hallucinations will be recruited and randomized into group A and group B. Participants of group A will firstly receive a speech competition training for 2 weeks, and those in group…
- Trial name
- NCT05850923
- Testing
- speech competition training, the soothing music
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Jing SHI