Clinical trials: Schizophrenia and Related Disorders
Major Depressive Disorder, Bi-Polar Disorder
DELPhI Evaluation of Psychiatric Conditions
DELPhI acquisition and analysis software, a QuantalX Neuroscience development, which is designed to measure, analyze, and display brain electrical activity of human electroencephalogram (EEG), to transcranial magnetic stimulation…
- Conditions
- Major Depressive Disorder, Bi-Polar Disorder, ADHD, Schizophrenia
- Trial name
- NCT03842345
- Sponsor
- QuantalX Neuroscience
Schizophrenia, Bipolar Disorder
Health Promotion and Fitness for Younger and Older Adults With SMI
The goal of this project, which has not changed, is to improve the health and fitness of persons with serious mental illness (SMI) using an innovative model: In SHAPE Lifestyles.
- Conditions
- Schizophrenia, Bipolar Disorder, Schizoaffective Disorder
- Trial name
- InSHAPE (NCT02090335)
- Testing
- In SHAPE, Fitness Club Membership
- Where
- 3 sites in United States
- Volunteers
- 210 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Obesity, Ketogenic Dieting
Impact of a Ketogenic Diet on Metabolic and Psychiatric Health in Patients With Bipolar or Schizophrenia Illness
To initiate a low-carbohydrate, high-fat (LCHF) or ketogenic dietary (KD) intervention among a cohort of outpatients with either schizophrenia or bipolar illness who also have metabolic abnormalities, overweight/obesity, and/or…
- Conditions
- Obesity, Ketogenic Dieting, Metabolic Syndrome, Bipolar Disorder
- Trial name
- NCT03935854
- Testing
- LCHF, Ketogenic Diet
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Stanford University
Traumatic Brain Injury, Major Depressive Disorder
Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations
In the current study, the investigators aim to understand the role of transcranial direct current stimulation (tDCS) in improving executive function across neuropsychiatric populations known to have deficits in this cognitive…
- Conditions
- Traumatic Brain Injury, Major Depressive Disorder, Bipolar Disorder, Schizophrenia
- Trial name
- NCT04296604
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Self Harm, Personality Disorders
Extreme Challenges - Psychopathology & Treatment Experiences Among Severly Selfharming Inpatients in Norway
Patients who self-harm are a heterogeneous population. Outpatient treatments structured for borderline personality disorder are often recommended and hospitalization kept to a minimum.
- Conditions
- Self Harm, Personality Disorders, Psychosis, Developmental Disorder
- Trial name
- NCT03768674
- Testing
- Assessment of diagnoses, functioning and health services
- Where
- Norway
- Volunteers
- 1,640 people
- Sponsor
- Oslo University Hospital
Severe Mental Illness, Schizophrenia
Group Intervention for Romantic Relationships in Young Adults With Severe Mental Illness
This study evaluates a group-based intervention designed to improve romantic and social relationship skills in adults living with a severe mental illness (SMI), such as schizophrenia, bipolar disorder, or major depressive…
- Conditions
- Severe Mental Illness, Schizophrenia, Bipolar Disorder, Major Depressive Disorder
- Trial name
- A2C'estMieuxVE (NCT07316803)
- Testing
- À deux, c'est mieux (Better Together) Group Intervention
- Where
- 2 sites in France
- Volunteers
- 20 people
- Sponsor
- Centre hospitalier de Ville-Evrard, France
Schizophrenia, Cannabis Abuse
Niacin Flushing as Marker of Cannabis Effects on Arachidonic Acid Pathways in Schizophrenia
Increasing evidence suggests modulating effects of cannabinoids on time of onset, severity, and outcome of schizophrenia. Efforts to discover the underlying pathomechanism have led to the assumption of gene x environment…
- Trial name
- NCT00376233
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Jena
Psychotic Disorders, Bipolar Disorder
Honest Open Proud for Psychotic and Bipolar Disorder in Norway
The purpose of this pilot study is to evaluate the feasibility, acceptability and efficacy of a Norwegian adaptation of the group-based intervention 'Honest Open Proud' among adults with psychotic and bipolar disorders in an…
- Conditions
- Psychotic Disorders, Bipolar Disorder, Disclosure
- Trial name
- HOP-NOR (NCT06384755)
- Testing
- Honest Open Proud program
- Where
- 2 sites in Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Type 2 Diabetes Mellitus, Serious Mental Illness
Lifestyle MIND- Feasibility of Wait-list Control
The goal of this clinical trial is to examine if it is feasible to randomly assign people into two groups and participate in Lifestyle MIND (Mental Illness and/N' Diabetes) at two different times.
- Conditions
- Type 2 Diabetes Mellitus, Serious Mental Illness, Schizophrenia, Major Depression
- Trial name
- MIND (NCT06384521)
- Testing
- Lifestyle MIND
- Where
- United States
- Sponsor
- The University of Texas Health Science Center at San Antonio
Schizophrenia, Major Depressive Disorder
General Practice Research Database Seroquel XR Safety Study
The main objective of this observational study is to characterize new users of quetiapine XR as well as new users of other study drugs (i.e.
- Conditions
- Schizophrenia, Major Depressive Disorder, Bipolar Disorder
- Trial name
- GPRD SeroquelS (NCT01447082)
- Where
- Switzerland
- Volunteers
- 37,372 people
- Sponsor
- AstraZeneca
Schizophrenia, Bipolar Disorder
Rochester Forensic Assertive Community Treatment Model in Minnesota
This study evaluates the Rochester Forensic Assertive Community Treatment (R-FACT) model in Minnesota. R-FACT is an enhanced version of Assertive Community Treatment designed to support individuals with serious mental illness who…
- Conditions
- Schizophrenia, Bipolar Disorder, Criminal Behavior
- Trial name
- R-FACT (NCT07592884)
- Testing
- R-FACT intervention, Standard Outpatient Treatment
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Rochester
Alcoholism, Schizophrenia
Facilitation of NMDA Receptor Function in Patients With Schizophrenia and Co-morbid Alcoholism
This placebo-controlled study is designed to evaluate the efficacy of glycine, an agonist of the glycine-B co-agonist site of the NMDA receptor, on alcohol consumption and craving as well as negative symptoms in schizophrenia.
- Trial name
- NCT00338598
- Testing
- Glycine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Yale University
Schizophreniform Disorders, Bipolar Disorder
REWRITALIZE Your Recovery - Evaluation of a Creative Writing Group Intervention
Health institutes call for psychosocial interventions and recovery-oriented approaches as supplement to pharmacological treatment for mental health disorders.
- Conditions
- Schizophreniform Disorders, Bipolar Disorder, Severe Depression, Ptsd
- Trial name
- REWR (NCT06251908)
- Testing
- Rewritalize, Standard mental health care
- Where
- 6 sites in Denmark
- Volunteers
- 300 people
- Sponsor
- Amager Hospital
Depressive Disorder, Major, Bipolar Disorder
In-person vs. Remote Wellness Support
The study team will use components of the Reach, Effectiveness, Adoption, Implementation, Maintenance (RE-AIM) framework to compare Cognitive Adaptation Training (CAT) to Remotely delivered Cognitive Adaptation Training (R-CAT)…
- Conditions
- Depressive Disorder, Major, Bipolar Disorder, Schizo Affective Disorder, Schizophrenia
- Trial name
- R-CAT (NCT04526067)
- Testing
- CAT, R-CAT
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Inhibition (Psychology), Schizophrenia
Prepulse Inhibition (PPI) of Startle Reflex in Schizophrenia Patients Related to Type of Treatment and Illness Duration
PPI is an objective measure to assess pre-attentive processes that have already been tested before in the case of schizophrenia.
- Conditions
- Inhibition (Psychology), Schizophrenia, Medication Adherence
- Trial name
- NCT02484521
- Testing
- PPI monitoring device protocol, Questionnaires
- Where
- Israel
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Schizophrenia
The Outcomes Among Persons With Schizophrenia Under the Peer-support Service in Vocational Rehabilitation Program
There are few programs related to vocational peer support services in persons with psychiatric disability in Taiwan. This study aims to develop a peer co-lead services in the community rehabilitation center and evaluate the…
- Trial name
- NCT04767204
- Testing
- peer co-delivered vocational rehabilitation service
- Where
- Taiwan
- Volunteers
- 46 people
- Sponsor
- Yu-Li Hospital
Attention Deficit Disorder With Hyperactivity, Bipolar Disorder
Genetic Aspects of Neurologic and Psychiatric Disorders
The purpose of this study is to improve the understanding of the genetic causes of specific neurologic and psychiatric disorders.
- Conditions
- Attention Deficit Disorder With Hyperactivity, Bipolar Disorder, Mental Disorder Diagnosed in Childhood, Mental Retardation
- Trial name
- NCT00001544
- Where
- United States
- Volunteers
- 1,227 people
- Sponsor
- National Institute of Mental Health (NIMH)
Schizophrenia
The Compliance Project Concerning People With Schizophrenia
The purpose of this study is to determine whether individual and/ or system orientated interventions can help the problem of people with schizophrenia dropping out of their drug treatment
- Trial name
- NCT00497848
- Testing
- motivational interviewing, The System-Orientated Intervention
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Ministry of the Interior and Health, Denmark
Schizophrenia, Schizophrenia and Related Disorders
Digital Implementation Support to Achieve Uptake and Integration of Task-Shared Care for Schizophrenia in Primary Care in India
Schizophrenia represents a significant contributor to the global burden of disease, with this burden disproportionately impacting low- and middle-income countries (LMICs).
- Conditions
- Schizophrenia, Schizophrenia and Related Disorders, Psychosocial Functioning
- Trial name
- NCT06043778
- Testing
- Community care for People with Schizophrenia in India (COPSI), mindLAMP Mobile Application
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
Mental Disorder, Recovery
Evaluation of Excellence in Italy's Residence for Execution of Security Measure
The model of care for forensic psychiatry in Italy was changed by law (Law 81/2014) so that the six legacy secure forensic hospitals (Judicial Psychiatric Hospitals, OPG) were closed and new secure community residences for the…
- Conditions
- Mental Disorder, Recovery, Schizophrenia and Related Disorders, Personality Disorders and Disturbances in Behavior
- Trial name
- ITAL-EE-REMS (NCT06018298)
- Testing
- Treatment as usual (TAU)
- Where
- Italy
- Volunteers
- 245 people
- Sponsor
- University of Bari