Clinical trials: Sciatic Nerve Block
Postoperative Analgesia, Anesthesia; Functional
Comparison of Two Regional Technics In Knee Artroplasty
Purpose: This prospective, randomised, controlled, single-blind, multicentre study was designed to investigate the effects of peripheral nerve block methods (applied using unilateral spinal anaesthesia [USA] on elderly patients…
- Trial name
- CTRTIKA (NCT03021421)
- Testing
- intratechal (subarachnoidal )injection, lombar plexus and sciatic nerve injection
- Volunteers
- 60 people
- Sponsor
- Ordu University
Orthopedic Disorder, Total Knee Replacement
Combined Adductor&Sciatic Nerve Block vs Femoral&Sciatic Nerve Block in Total Knee Replacement Surgery
Knee joints, one of the largest and most functional joints of the human body, have great features to provide ideal body posture and movement.
- Conditions
- Orthopedic Disorder, Total Knee Replacement, Post Operative Pain, Surgery
- Trial name
- NCT05648708
- Testing
- Combine Adductor Canal & Sciatic Nerve Block, Combine Femoral & Sciatic Nerve Block, Bupivacaine and prilocaine hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Surgical Pathology of the Leg or the Foot.
Pharmacokinetic of levobupivacaïne After Sciatic Nerve Block in Children
Levobupivacaïne (Chirocaine®) is a new local anaesthetic recently marketed in France. The goal of this prospective work is to study the pharmacokinetic aspect of this drug after injection around the sciatic nerve (subgluteal way).
- Trial name
- NCT00682344
- Testing
- Levobupivacaïne
- Where
- France
- Volunteers
- 7 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Tourniquet Hypertension
A Long Axis Approach to the Femoral Artery Block (FAB) for Managing Tourniquet Pain and Hypertension in Below-the-Knee Fracture Surgery
This is a prospective, randomized, double-blind controlled trial evaluating an ultrasound-guided femoral artery block (FAB) using a long-axis in-plane approach compared with a short-axis approach and a control group.
- Trial name
- FAB (NCT07548567)
- Testing
- Femoral artery block - short-axis, Femoral artery block - long-axis, Normal saline injection (control)
- Where
- Greece
- Volunteers
- 84 people
- Sponsor
- National and Kapodistrian University of Athens
Injuries to the Ankle and Foot
Minimum Effective Volume of Lidocaine-Bupivacaine for Subgluteal Block
The aim of this study is to determine the minimum effective volume of LA in 90 % of patients (MEV90) required for US-guided subgluteal sciatic nerve block.
- Trial name
- NCT02571699
- Testing
- Subgluteal Nerve Block
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Hallux Valgus, Bunionectomy
Sciatic Nerve Block With ALX006 in Subjects Undergoing Bunionectomy
This is a Phase 2, randomized, double-blind, active-controlled, dose-escalation study evaluating the safety, pharmacokinetics, efficacy, and pharmacodynamics of ALX006, an extended-release bupivacaine formulation, administered as…
- Trial name
- NCT07574385
- Testing
- ALX006 (bupivacaine extended-release injection), Bupivacaine Hcl 0.25% Inj, Sciatic Nerve Block
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Rebel Medicine Inc
Lower Extremity Surgery, Upper Extremity Surgery
Perineural Catheter Insertion Distance for Continuous Peripheral Nerve Blocks
This is a research study to determine if the effects of continuous peripheral nerve blocks are influenced by the distance of insertion past the needle tip of the perineural catheter.
- Conditions
- Lower Extremity Surgery, Upper Extremity Surgery, Post-operative Pain
- Trial name
- NCT00997867
- Testing
- Sciatic catheter left 0-1cm past needle tip vs. 5-6cm past needle tip
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- University of California, San Diego
Phantom Limb Pain
Pre-emptive Sciatic Bloc to Prevent Lower Limb Phantom Pain
Phantom limb pain is a complication of amputation. Although pre-empitve epidural analgesia was once thought to prevent such a com plication, recent studies did not demonstrate this.
- Trial name
- NCT00528463
- Testing
- sciatic nerve block
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- Université de Sherbrooke
Adult, Regional Anesthesia Morbidity
How Do We Ultrasound-Guided Popliteal Approach Sciatic Nerve Block?
The aim of this prospective, randomized, observer-blind study to compare subparaneural approach injection with interneural approach injection in popliteal sciatic nerve blocks.
- Conditions
- Adult, Regional Anesthesia Morbidity, Anesthesia Injection Site
- Trial name
- NCT06372691
- Testing
- Subparaneural Injection (Grup S), Block, Interneural Injection (Grup I), Block
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Ankle Disease, Foot Diseases
Dexamethasone vs Dexmedetomidine vs Combination as Adjuvants to Popliteal Sciatic Nerve Block in Children
This clinical study will evaluate three commonly used medications that can be added to local anesthetic during a popliteal sciatic nerve block in children undergoing surgery of the lower leg or foot.
- Trial name
- NCT07289620
- Testing
- Dexamethasone, Dexmedetomidine, Dexamethasone + Dexmedetomidine
- Where
- Poland
- Volunteers
- 120 people
- Sponsor
- Poznan University of Medical Sciences
Postoperative Pain
Postoperative Pain Management for Hip Surgeries: UltrasoundGuided Suprainguinal Fascia Iliaca Compartment Block Versus Suprainguinal Fascia Iliaca Compartment Block in Combination With Sciatic Nerve Block
The aim of the Study is to compare the analgesic efficacy and clinical outcomes of suprainguinal fascia iliaca block (SIFIB) alone versus SIFIB combined with sciatic nerve block (SNB) in patients undergoing hip surgery.
- Trial name
- NCT07787442
- Testing
- Bupivacaine injection
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Pain
Comparison of Ultrasound and Nerve Stimulation Technique for Continuous Sciatic Nerve Block
The most useful method to manage pain after major foot and ankle surgery is infusion of local anesthetic with a catheter close to the sciatic nerve in the popliteal space above the knee joint.
- Trial name
- NCT00497276
- Testing
- placement of popliteal catheter
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Anesthesia
Application of Combined Lumbar Plexus and Sciatic Nerve Block
The research is to study the effectiveness and safety of combined lumbar plexus and sciatic nerve block by the guide of peripheral nerve stimulator (PNS) in unilateral knee replacement.There have be some papers which supported…
- Trial name
- NCT02084368
- Testing
- Nerve block, Combined spinal and epidural anesthesia, Ropivacaine
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Ankle Fractures, Leg Fracture
Sciatic Nerve Block for Ankle and Leg Fracture Manipulation in the Emergency Department
The goal of this feasibility clinical trial is to assess the acceptability of ultrasound-guided sciatic nerve block when performed at Emergency Departments for manipulation and temporary stabilization of distal leg and ankle…
- Trial name
- AnkleMan (NCT06329752)
- Testing
- Ultrasound-guided Sciatic Nerve block (20 mL of 2% Lidocaine)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Foot Surgery
Ultrasound-Guided Continuous Sciatic Nerve Blocks: Popliteal Versus Subgluteal Catheters
To determine the relationship between perineural catheter location along the sciatic nerve (popliteal versus subgluteal placement) and infusion effects for ultrasound-guided continuous sciatic nerve blocks.
- Trial name
- NCT01325012
- Testing
- Subgluteal Sciatic Nerve Block, Popliteal Sciatic Nerve Block
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- University of California, San Diego
Total Knee Arthroplasty, Adductor Canal Block
Analgesic Efficacy of Adding SCB With Low Concentration Bupivacaine Combined With Dexamethasone on Pain After TKA
This study evaluate the efficacy of adding popliteal sciatic nerve block with low concentration bupivacaine and dexamethasone to abductor canal block for total knee arthroplasty in patient with NSAIDs prescribing precaution.
- Conditions
- Total Knee Arthroplasty, Adductor Canal Block, Sciatic Nerve Block
- Trial name
- NCT03486548
- Testing
- bupivacaine and dexamethasone, bupivacaine and lidocaine, Ultrasound
- Where
- Thailand
- Volunteers
- 50 people
- Sponsor
- Mahidol University
Post Operative Analgesia, Regional Anesthesia
Does Interneural Local Anesthetic Spread at the Site of Sciatic Nerve Bifurcation Shorten Block Onset Time?
Following foot and ankle surgery, ultrasound-guided sciatic nerve block (SNB) at the popliteal fossa decreases post-operative pain and opioid consumption.
- Conditions
- Post Operative Analgesia, Regional Anesthesia, Sciatic Nerve Block
- Trial name
- NCT01568476
- Testing
- Distal, Interneural
- Where
- Canada
- Volunteers
- 88 people
- Sponsor
- University Health Network, Toronto
Knee Arthritis
Spinal Anesthesia Versus Combined Sciatic-femoral Nerve Block for Outpatient Knee Arthroscopy
The aim of the study is to compare the time of home discharge in day-case patients receiving either a spinal anesthesia or a combined sciatic-femoral nerve block for knee arthroscopy
- Trial name
- NCT02384915
- Testing
- prilocaine, mepivacaine, Sciatic-femoral Nerve Block
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- ASST Gaetano Pini-CTO
Arthropathy of Knee Joint
Evaluation of Optimal Dose of Local Anesthetics for Patient Controlled Continuous Femoral Nerve Block
To evaluate an analgesic effect without basal administration of local anesthetics for patient-controlled femoral nerve block (with sciatic nerve block) after total knee arthroplasty.
- Trial name
- NCT01198340
- Testing
- PC-FNB with basal administration of local anesthetics, PC-FNB without basal local anesthetics
- Where
- Japan
- Volunteers
- 60 people
- Sponsor
- Okayama University
Pain, Sciatic Block
Trial Comparing Duration of Analgesia After Popliteal Fossa Sciatiac Nerve Block With Ropivacaine 0.5% When Combined With Placebo, Dexamethasone 4mg or Dexamethasone 8 mg
The purpose is to find out if the addition of dexamethasone to ropivacaine 0.5% increases the duration of pain relief provided by popliteal sciatic nerve block performed for foot/ankle surgery.
- Trial name
- NCT01641419
- Testing
- Dexamethasone 4 mg, Dexamethasone 8 mg
- Where
- United States
- Sponsor
- Baylor College of Medicine