Clinical trials: Sciatic Neuropathy
Lumbar Radiculopathy
Safety and Efficacy of SX600 Administered by Lumbosacral Transforaminal Epidural Injection for Radicular Pain
This is a Phase I/II, double-blind, parallel-group, randomized, placebo-controlled multi-centre trial in 180 patients randomized 1:1:1 to receive the IMP (Dexamethasone acetate microspheres for extended-release injectable…
- Trial name
- SALIENT (NCT03952377)
- Testing
- SX600
- Where
- 10 sites in Australia
- Volunteers
- 56 people
- Sponsor
- SpineThera Australia PTY LTD
Low Back Pain, Sciatica
Management Strategies for Patients With Low Back Pain and Sciatica
Low back pain and sciatica is a common condition resulting in high costs and disability for society and affected individuals. Presently there is a lack of evidence for what treatments may help this condition early in the course…
- Conditions
- Low Back Pain, Sciatica, Physical Therapy
- Trial name
- NCT02391350
- Testing
- Education and re-assurance, Physical Therapy
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of Utah
Lumbar Disc Herniation With Radiculopathy, Sciatica
FINDISC-Pain, Finnish Discectomy Trial on the Benefits and Harms of Surgery in Patients With Lumbar Disc Herniation
The FINDISC trial studies whether common back operation, microdiscectomy, is effective and safe for treating sciatica caused by a lumbar disc herniation.
- Trial name
- FINDISC-Pain (NCT07418944)
- Testing
- Microdiscectomy
- Where
- Finland
- Volunteers
- 122 people
- Sponsor
- Helsinki University Central Hospital
Piriformis Syndrome
Effects of Hip Abductor Strengthening Exercises in Patients With Piriformis Syndrome
The study was conducted to determine the effects of hip abductor strengthening exercises on pain, range of motion, and lower extremity function in patients with piriformis syndrome.
- Trial name
- NCT07484373
- Testing
- Progressive Hip Abductor Strengthening Exercises, conventional physiotherapy treatment
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Riphah International University
Sciatica, Intervertebral Disc Disorder
Alternative and Integrative Therapy for Lumbar Disk Herniation
The investigators report management of lumbar disc herniation with severe sciatic pain using an integrative complementary and alternative medicine approach with a 5 year follow-up.
- Trial name
- NCT01989403
- Testing
- herbal medicine, acupuncture, bee-venom acupuncture, and Chuna manipulation
- Where
- South Korea
- Volunteers
- 128 people
- Sponsor
- Jaseng Hospital of Korean Medicine
Sciatica, Spinal Stenosis of Lumbar Region
Prolotherapy Versus Epidural Steroid Injections (ESI) for Lumbar Pain Radiating to the Leg
The hypothesis is that in the treatment of low back pain (LBP) radiating to the leg, the long-term results of prolotherapy are more effective than those of the current conventional treatment: epidural steroid injections (ESI).
- Conditions
- Sciatica, Spinal Stenosis of Lumbar Region, Degeneration of Lumbar or Lumbosacral Intervertebral Disc
- Trial name
- NCT01934868
- Testing
- prolotherapy solution of 20% dextrose, Epidural Steroid Injection
- Where
- Israel
- Volunteers
- 110 people
- Sponsor
- Hadassah Medical Organization