Clinical trials: Scoliosis; Adolescence
Adolescent Idiopathic Scoliosis
The Effect of the Inspiratory Muscle Training on Respiratory Parameters and Functional Capacity in Idiopathic Scoliosis
Scoliosis is the abnormality of the spine with direct effects on the shape and mechanics of the thoracic cage. Adolescent Idiopathic Scoliosis (AIS) is the most common 3-dimensional deformity of the spine which can potentially…
- Trial name
- NCT03391895
- Testing
- Home based exercise program, Inspiratory Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Bezmialem Vakif University
Scoliosis, Vitamin D
6 Years Study on Changes in Bone Quality, Bone Turnover and Curve Severity in AIS With and Without Calcium and Vit-D Supplementation
The study aimed to: 1. To investigate and compare the changes in bone mineral density (BMD), trabecular bone micro-architecture, bone strength, and curve severity at a mean of 6 years longitudinal follow up in AIS girls with low…
- Conditions
- Scoliosis, Vitamin D, Bone
- Trial name
- NCT02904421
- Where
- China
- Volunteers
- 330 people
- Sponsor
- Chinese University of Hong Kong
Adolescent Idiopathic Scoliosis
3D, Dynamic and Mechanically-informed Decision Making in AIS
Adolescent Idiopathic Scoliosis (AIS) is a growth defect of the spine that primarily occurs in prepubertal children between the age of 10 to 14 years, affecting approximately 3% of these otherwise normal children.
- Trial name
- 3D-AIS (NCT04761549)
- Testing
- Adolescent Idiopathic Scoliosis
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Scoliosis; Adolescence
Investigation of the Efficacy of PNF and Schroth Treatment
our study was to compare the advantages of Schroth and PNF methods used in AIS treatment
- Trial name
- NCT05227638
- Testing
- exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Mehmet Hanifi Kaya
Adolescent Idiopathic Scoliosis, Multimodal Analgesia
Propofol + Remifentanil vs. Propofol + Dexmedetomidine in Adolescent Idiopathic Scoliosis Patients Having Spine Surgery
Patients with Adolescent Idiopathic Scoliosis may need surgery to correct their scoliosis. General anesthesia is required for this surgery, and a multimodal analgesic regimen using combinations of opioid and non-opioid…
- Conditions
- Adolescent Idiopathic Scoliosis, Multimodal Analgesia, Opioid Induced Hyperalgesia, Remifentanil
- Trial name
- NCT06096181
- Testing
- Remifentanil TIVA, Dexmedetomidine TIVA, Propofol TIVA
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Adolescent Idiopathic Scoliosis
Green Sun Medical Dynamic Brace
The Green Sun Medical Dynamic Brace (GSM) brace was developed as an alternative to rigid thoracolumbosacral orthoses (TLSOs, braces) commonly used to prevent continued curve progression in patients with adolescent idiopathic…
- Trial name
- NCT04877236
- Testing
- Green Sun Medical Brace
- Where
- United States
- Sponsor
- Children's Hospital Los Angeles
Scoliosis Idiopathic Adolescent
SIMDiscovery: The Benefits of Utilizing a Simulation Preparation Program for Spinal Fusion Surgery
This is a pilot study aiming to examine preliminary effectiveness of a preparation program which includes simulation (SIMDiscovery) in reducing anxiety and increasing feelings of preparedness among parents and their children who…
- Trial name
- NCT03835390
- Testing
- SIMDiscovery
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Boston Children's Hospital
Adolescent Idiopathic Scoliosis
The Effects of Core Stability Training in Children With Adolescent Idiopathic Scoliosis
Adolescent idiopathic scoliosis (AIS) is a three-dimensional structural deformity of the spine in which lateral flexion and axial rotation are seen in vertebrae with a Cobb (method for measuring spinal curvature) angle of 10° and…
- Trial name
- NCT05056363
- Testing
- Home Based Traditional Scoliosis Exercises, Core Stability Training
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Istanbul University
Scoliosis Idiopathic, Telerehabilitation
Telerehabilitation Support for Home Exercise in Mild AIS
Adolescent idiopathic scoliosis (AIS) is a three-dimensional spinal deformity that affects postural alignment, function, and quality of life.
- Conditions
- Scoliosis Idiopathic, Telerehabilitation, Exercise
- Trial name
- NCT07260383
- Testing
- home exercise, telerehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Juvenile Idiopathic Scoliosis, Adolescent Idiopathic Scoliosis
Study of the Braive Growth Modulation System for Progressive Pediatric Scoliosis
The purpose of this study was to establish probable benefits and evaluate the safety and preliminary effectiveness of the Braive™ GMS when used in the treatment of pediatric progressive scoliosis.
- Trial name
- BRAIVE IDE (NCT04929678)
- Testing
- Braive™ Growth Modulation System (Braive™ GMS)
- Where
- 4 sites in United States, Canada and 1 more
- Volunteers
- 10 people
- Sponsor
- Medtronic Spinal and Biologics
Adolescent Idiopathic Scoliosis
Spinal Balance With Wearables - Case-control
Observational case-control study to see if the Margin of Stability and Dynamic Postural Stability (measured using a motion capture gait laboratory and wearable device, respectively) are different in children with Adolescent…
- Trial name
- NCT04735484
- Testing
- Gait analysis
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University College, London
Adolescent Idiopathic Scoliosis
Dynamic Pressure Monitoring System for Orthotic Treatment of Scoliosis
Adolescent idiopathic scoliosis (AIS) involves three-dimensional spinal deformity in children aged between 10 and 16. Traditional braces modify the natural dynamics and thus the mechanical behaviour of the scoliotic spine through…
- Trial name
- NCT03716843
- Testing
- Pressure monitoring system
- Where
- Hong Kong
- Volunteers
- 20 people
- Sponsor
- The Hong Kong Polytechnic University
Scoliosis; Adolescence
Use of Intravenous Acetaminophen in Pediatrics Undergoing Spinal Fusion Surgery
The purpose of this study is to investigate whether perioperative intravenous acetaminophen administration reduces postoperative pain and opioid consumption in adolescents and pediatric patients undergoing spinal fusion surgery.
- Trial name
- NCT04959591
- Testing
- intravenous acetaminophen
- Where
- South Korea
- Volunteers
- 99 people
- Sponsor
- Asan Medical Center
Adolescent Idiopathic Scoliosis, Osteogenesis Imperfecta
Experimental Evaluation of Back Braces for the Treatment of Spinal Deformity Produced With 3D Printing Technology
The proposed investigation is a pilot study that involves pediatric patients affected by spinal deformity (Adolescent Idiopathic Scoliosis and Osteogenesis Imperfecta).
- Trial name
- NCT04282408
- Testing
- Scoliosis back brace
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- IRCCS Eugenio Medea
Scoliosis; Adolescence
Scoliosis Survey to Development Treatment Decision Tool
This is a survey to help understand the influences related to the decision for Adolescent Idiopathic Scoliosis treatment (observation vs. bracing vs. surgery).
- Trial name
- NCT03017755
- Testing
- Survey for Patients Treated for Scoliosis and ther Families
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Mayo Clinic
Scoliosis Idiopathic Adolescent
Efficacy of Physiotherapeutic Scoliosis Specific Exercises in Adolescent Idiopathic Scoliosis
Adolescent idiopathic scoliosis (AIS) has a relatively high prevalence in adolescents. Exercise is the most common conservative therapy for mild AIS patients.
- Trial name
- NCT02968043
- Testing
- physiotherapeutic scoliosis specific exercises, generalised physiotherapy exercises
- Where
- 2 sites in China
- Volunteers
- 42 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Adolescent Idiopathic Scoliosis
Analysis of Prognostic Cell Signaling Factors in Adolescent Idiopathic Scoliosis
The purpose of this study is to identify potential markers for curve progression in adolescent idiopathic scoliosis (AIS). Despite its prevalence and impact on child health, the etiology of AIS and molecular mechanisms underlying…
- Trial name
- NCT02315729
- Where
- United States
- Volunteers
- 380 people
- Sponsor
- University of Colorado, Denver
Adolescent Idiopathic Scoliosis (AIS), Scoliosis; Adolescence
Effects of Expiratory Muscle Strength Training in Adolescent Idiopathic Scoliosis
Adolescent idiopathic scoliosis result in deterioration of core muscles and respiratory system. Core muscles provide trunk stabilization as well as responsible for respiratory system. Especially tr.
- Trial name
- NCT06752993
- Testing
- Expiratory Muscle Strength Training (EMST-150)
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Gazi University
Adolescent Idiopathic Scoliosis
Long-term Effectiveness of Integrative Scoliosis-specific Rehabilitation in High-risk Adolescent Idiopathic Scoliosis
Adolescent idiopathic scoliosis (AIS) is one of the most common spinal deformities diagnosed in adolescents, especially female, with the prevalence in general population ranging from 0.93% to 12%, 80% of which are idiopathic.
- Trial name
- NCT06672029
- Testing
- combining pattern-specific manual therapy, Schroth Best Practice exercise, and Gensingen brace application
- Where
- Taiwan
- Volunteers
- 54 people
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Spine Deformity, Idiopathic Scoliosis
Advanced SPinal Innovations With Robotics and Enabling Technology Registry
Creation of a pediatric robotic spine surgery registry will allow for data collection and analysis on the coupled use of robotics and navigation, as well as patient-specific rods in pediatric spine deformity surgery across…
- Conditions
- Spine Deformity, Idiopathic Scoliosis, Adolescent Idiopathic Scoliosis, Spondylolisthesis
- Trial name
- ASPIRE (NCT05071144)
- Where
- 10 sites in United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital