Clinical trials: Scoliosis
Lumbar Disc Herniation, Lumbar Spinal Stenosis
Nurse-Led Early Standing Exercise After Lumbar Fusion in Older Adults
This single-center, randomized controlled trial aimed to evaluate the effects of a nurse-led early standing active exercise program on postoperative functional recovery in older adults undergoing short-segment lumbar fusion.
- Conditions
- Lumbar Disc Herniation, Lumbar Spinal Stenosis, Lumbar Spondylolisthesis, Degenerative Lumbar Scoliosis
- Trial name
- NCT07870993
- Testing
- Nurse-Led Early Standing Active Exercise Program, Routine Postoperative Rehabilitation
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Xuanwu Hospital, Beijing
Adolescent Idiopathic Scoliosis, Postoperative Pain, Acute
The Use of a Comfort Tote to Improve Recovery in Pediatric and Adolescent Patients After Surgery
The goal of this clinical trial is to learn if the use of Comfort Tote can treat pain and anxiety in adolescents with idiopathic scoliosis undergoing posterior spinal fusion. The study aims to answer two questions: 1.
- Conditions
- Adolescent Idiopathic Scoliosis, Postoperative Pain, Acute, Postoperative Nausea and Vomiting, Anxiety
- Trial name
- NCT07632833
- Testing
- The Therapeutic Comfort Tote, The Modified Comfort Tote
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Columbia University
Scoliosis, Kyphosis
Postoperative and Chronic Pain Genetic Spine and Pectus Surgery Study
This will be an open label, prospective study to determine the association between specific genotypes, epigenetics and behavioral factors, with the phenotypes, defined by pain perception, postoperative pain, analgesic and side…
- Conditions
- Scoliosis, Kyphosis, Kyphoscoliosis, Pectus Excavatum
- Trial name
- NCT02998138
- Where
- 5 sites in United States
- Volunteers
- 880 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Pain, Postoperative, Excavatum, Pectus
Comprehensive Study of Post-surgical Pain After Pectus or Spine Surgery
This will be a prospective observational study to determine the association between specific genotypes, epigenetics, behavioral, social and biological factors, with the phenotypes, defined by pain perception, postoperative pain…
- Conditions
- Pain, Postoperative, Excavatum, Pectus, Scoliosis Idiopathic
- Trial name
- NCT04031716
- Testing
- Meditation
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Idiopathic Scoliosis
Evaluation of Analgesia for Spine Fusion Elective Surgery in Children
The multicenter PRECISE Analgesia (Prospective Randomized Evaluation of Analgesia for Idiopathic Scoliosis Spine Fusion Elective Surgery in Children) trials will a) implement and investigate the efficacy and safety of multidose…
- Trial name
- PRECISE (NCT06626503)
- Testing
- Methadone based ERAS, Non-methadone based group
- Where
- 4 sites in United States
- Volunteers
- 500 people
- Sponsor
- Senthil Sadhasivam
Adolescent Idiopathic Scoliosis
Immediate Effects of Self-Corrective Training in Adolescent Idiopathic Scoliosis: A Nested Study
This nested study was conducted within a broader adolescent idiopathic scoliosis research protocol approved under IRB UW24-747. It evaluated immediate within-session changes in bilateral muscle-activation asymmetry and posterior…
- Trial name
- NCT07194564
- Testing
- Fixed-Sequence Exercise and Self-Corrective Posture Training
- Where
- Hong Kong
- Volunteers
- 36 people
- Sponsor
- The University of Hong Kong
Scoliosis, Respiratory Function
The Effect of Curve Type Determined According to the Rigo Classification on Respiratory Muscle Strength, Quality of Life, and Functional Status in Individuals Diagnosed With Adolescent Idiopathic Scoliosis.
Adolescent Idiopathic Scoliosis (AIS) is a disorder that occurs between the ages of 10 and 18, with an unknown etiology, and is characterized by a three-dimensional deformity of the spine.
- Conditions
- Scoliosis, Respiratory Function, Rigo Classification, MIP
- Trial name
- NCT07863492
- Volunteers
- 120 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Adolescent Idiopathic Scoliosis, Postural Balance
Feedback-Based Balance Training for Adolescents With Idiopathic Scoliosis
Adolescent idiopathic scoliosis (AIS) is the most common form of scoliosis occurring during the growth period and is associated with significant alterations in postural balance compared with healthy peers.
- Trial name
- NCT07430098
- Testing
- HUBER® 360 Balance Training, Home-Based Balance Exercise Program, Individualized Conservative Scoliosis Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Ankara Etlik City Hospital
Spinal Fusion, Adolescent Idiopathic Scoliosis
Low Dose Dexmedetomidine as a Postoperative Pain Adjunct
This randomized controlled trial examines whether the addition of a low-dose dexmedetomidine infusion to our current multimodal pain management plan decreases narcotic consumption and reduces side effects in adolescent patients…
- Trial name
- NCT06067893
- Testing
- Dexmedetomidine, Normal Saline
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Nichole Doyle
Adolescent Idiopathic Scoliosis (AIS)
Validation of the Clinical Decision Support Systems (CDSS) Developed in the EU Horizon PREPARE Project in the Rehabilitative Treatment of Idiopathic Scoliosis
The study aims to validate both the predictive capacity and the clinical usability of the Clinical Decision Support System (CDSS) developed within the PREPARE project (European Union Grant Agreement 101080288 PREPARE…
- Trial name
- PREPARE (NCT07379593)
- Testing
- CDSS simulation, Focus group - clinicians, Focus group - patients
- Where
- Italy
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Istituto Scientifico Italiano Colonna Vertebrale
Adolescent Idiopathic Scoliosis (AIS)
Hypnosis for Pain and Nausea Reduction in Scoliosis Surgery: An Interventional Study
This study evaluates whether preoperative hypnosis can reduce postoperative pain, nausea, and opioid use in adolescents undergoing scoliosis surgery. Participants aged 12-18 years will receive hypnosis training before surgery.
- Trial name
- HYP-SCOL (NCT07854951)
- Testing
- Hypnosis
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- St. Olavs Hospital
Fracture, Scoliosis Idiopathic Adolescent
Opioid Analgesia Impacts on Neurological Development
Background: Pain in childhood - whether from injuries like fractures or long-term conditions like scoliosis - is often treated with opioid medicines. These drugs are effective for pain relief.
- Conditions
- Fracture, Scoliosis Idiopathic Adolescent, Traumatic Injury, Adolescent
- Trial name
- OPAL (NCT07855952)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Nottingham
Minor, Scoliosis; Juvenile
Evaluation of a Prehabilitation Program in Patients Requiring Scoliosis Surgery.
Scoliosis is a curvature of the spine that, in the most severe cases, may require surgical treatment. This surgery is invasive and complex, causing anxiety for children, adolescents, and their parents.
- Conditions
- Minor, Scoliosis; Juvenile, Scoliosis; Adolescence, Surgery
- Trial name
- PHYPSYSCOL (NCT07852286)
- Testing
- Pre-habilitation program
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Grenoble
Scoliosis Idiopathic Adolescent, Cyberchondria
Cyberchondria in Adolescents With Idiopathic Scoliosis
Scoliosis is a three-dimensional torsional deformity of the spine and trunk characterized by alignment abnormalities in the coronal plane, the presence of axial rotation in the horizontal plane, and abnormalities in the normal…
- Trial name
- NCT07481071
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Scoliosis Idiopathic
A Prospective Analysis of Long-Term Clinical Outcomes and 3D Spine Growth in Anterior Vertebral Body Tethering
Anterior vertebral body tethering (AVBT) is a novel, minimally invasive, growth modulation technique that was recently approved by the FDA under a Humanitarian Device Exemption (HDE).
- Trial name
- NCT04914507
- Testing
- Anterior Vertebral Body Tethering
- Where
- 12 sites in United States, Canada
- Volunteers
- 106 people
- Sponsor
- Pediatric Spine Foundation
Adolescent Idiopathic Scoliosis
Diaphragm Mobilization in Adolescent Idiopathic Scoliosis
Adolescent idiopathic scoliosis (AIS) is a three-dimensional spinal deformity that can affect posture, trunk movement, and respiratory function.
- Trial name
- NCT07482748
- Testing
- Diaphragm Mobilization, Schroth Best Practice Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Marmara University
Early-Onset Scoliosis Deformity of Spine
Hospital-Based Cluster Trial: Magnetically Controlled Growing Rods Using Distraction Intervals
A hospital-based cluster stratified randomization control study will be conducted to investigate spinal growth in Early Onset Scoliosis patients between 5 and 9 years of age.
- Trial name
- MCGR (NCT04058561)
- Testing
- MAGEC® Spinal Bracing And Distraction System
- Where
- 20 sites in United States, Canada and 2 more
- Volunteers
- 210 people
- Sponsor
- Pediatric Spine Foundation
Juvenile; Scoliosis, Scoliosis Idiopathic
Digital Health Psychosocial Intervention for Adolescent Spine Surgery Preparation and Recovery
This is a randomized controlled trial to test effectiveness of the SurgeryPal intervention vs. education control to improve acute and chronic pain and health outcomes in youth undergoing major musculoskeletal surgery.
- Conditions
- Juvenile; Scoliosis, Scoliosis Idiopathic, Scoliosis; Adolescence, Scoliosis;Congenital
- Trial name
- SurgeryPal (NCT04637802)
- Testing
- CBT (SurgeryPal), Education
- Where
- United States
- Volunteers
- 433 people
- Sponsor
- Seattle Children's Hospital
Idiopathic Scoliosis
Multicentric Evaluation of Enhanced Recovery After Surgery Protocol in Adolescent Idiopathic Scoliosis Surgery
Adolescent idiopathic scoliosis is a deformation of the spine affecting 2 to 4% of under 18 years old population. This can have severe physical or psychological impact during adulthood.
- Trial name
- EMRACSIA (NCT06908213)
- Testing
- Posterior vertebral fusion surgery with Enhanced Recovery After Surgery (ERAS) procedure, Posterior vertebral fusion surgery with standard of care procedure
- Where
- 11 sites in France
- Volunteers
- 316 people
- Sponsor
- Hospices Civils de Lyon
Scoliosis
Effect of Treatment on Activity and Muscle Function in Pediatric Patients With Scoliosis
This study will explore the relationship between skeletal muscle and physical activity in scoliosis patients to provide insight into both the etiology of scoliosis and potential ways to mitigate the potential harms of treatment.
- Trial name
- SAMUS SCOLI (NCT02610855)
- Testing
- Spinal Fusion Surgery, Bracing, Tri-axial Accelerometers
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Mayo Clinic