Clinical trials: Scoring Systems
Periodontal Diseases, Periodontitis
HALP Score, Blood-Based Inflammatory Indices, and Salivary MMP-8 in Periodontal Disease and Healing After Non-Surgical Therapy
This observational clinical study aims to investigate the relationship between the HALP score (Hemoglobin × Albumin × Lymphocyte / Platelet), several blood-based inflammatory indices (including NLR, PLR, LMR, and SII), and…
- Conditions
- Periodontal Diseases, Periodontitis, Gingivitis; Chronic
- Trial name
- NCT07312045
- Testing
- Non-surgical Periodontal Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ömer Faruk Okumuş
Spinal Cord Injuries, Multiple Sclerosis
Polish Translation and Validation of NBSS, Qualiveen and SF-Qualiveen
The aim of this study is to translate, culturally adapt, and validate Polish versions of the NBSS, Qualiveen and SF-Qualiveen questionnaires.
- Trial name
- NCT04185792
- Testing
- NBSS, Qualiveen and SF-Qualiveen
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Jagiellonian University
Cystic Fibrosis
Fidgety Movements in Cystic Fibrosis
Very low birth weight infants who are at risk for chronic lung diseases may also be at risk for brain anomalies such as increased echogenicity, leukomalacia and intracranial hemorrhage.
- Trial name
- NCT03381157
- Testing
- Observational General Movements Assessments
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Rectal Cancer
Italian Validation of the LARS Score
BACKGROUND and RATIONALE Colorectal cancer, with 49,000 new diagnoses expected in 2019 (27,000 in men and 22,000 in women) represents, in Italy, the third neoplasm in men (14%) and the second in women (12%).
- Trial name
- NCT04406311
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Ovarian Cancer
Doppler Ultrasound and CT Versus Laparoscopy in Assessment of Ovarian Malignancy
The aim of this study is to assess validation of ultrasound (± Doppler) parameters in the diagnosis of suspicious ovarian malignant tumors and laparoscopic assessment of these findings according to Fagotti score evaluation of…
- Trial name
- NCT06109545
- Testing
- Laparoscopy
- Where
- Egypt
- Volunteers
- 95 people
- Sponsor
- Mansoura University
Hepatocellular Carcinoma
TACE Combined With ICIs Plus MTT After 125I Irradiation Stent Placement in HCC With Main PVTT.
Hepatocellular carcinoma (HCC) patients with Vp4 [main trunk] portal vein tumor thrombosis (PVTT) face a significantly poor prognosis, and current treatment options provide limited benefits.
- Trial name
- NCT06669377
- Where
- China
- Volunteers
- 444 people
- Sponsor
- Zhongda Hospital
Deterioration of Patient's State of Health
Development of an Automatically Generated and Wearable-based Early Warning System
The aim of this project is to create an automated EWS and analyze whether the use of wearable devices is suitable for vital sign measurements in a hospital by using the recording of vital parameters taken by nurses via the…
- Trial name
- NCT05699967
- Testing
- data collection
- Where
- Switzerland
- Volunteers
- 210 people
- Sponsor
- University Hospital, Basel, Switzerland
Chronic Urticaria, Urticaria
A Single-Arm Exploratory Study of NatureU Hista Dissolve on Chronic Urticaria Symptoms
This was a single-center, open-label, single-arm, exploratory self-controlled study evaluating NatureU Histra Disslove in adults with chronic urticaria symptoms.
- Conditions
- Chronic Urticaria, Urticaria, Angioedema
- Trial name
- NUHISTRA (NCT07611032)
- Testing
- NatureU Histra Disslove
- Where
- China
- Volunteers
- 19 people
- Sponsor
- OmniSolutions Laboratory Holdings Limited
Epithelial Ovarian Cancer
Health-Economic Evaluation of Early Diagnosis of Epithalial Ovarian Cancer Recurrence Using the ROMA Score: a Prospective Multicenter Randomized Trial
In this study, we hypothesize that calculating the ROMA score (CA125 + HE4 blood marker assay) will enable faster, more targeted diagnosis and management of epithelial ovarian cancer recurrence than the CA125 marker assay alone.
- Trial name
- ROMECO (NCT05991752)
- Testing
- ROMA score evaluation
- Sponsor
- University Hospital, Tours
Appendicitis, Abdominal Pain
The Value of Pancreatic Stone Protein in Predicting Acute Appendicitis
PSP (Pancreatic Stone Protein) is a compound naturally produced mainly in the pancreas and the gut. There is evidence from experimental and clinical trials that the levels of PSP in the blood rise in the presence of inflammation…
- Conditions
- Appendicitis, Abdominal Pain, Abdominal Sepsis
- Trial name
- NCT01610193
- Testing
- Appendicectomy
- Where
- 2 sites in Switzerland
- Volunteers
- 245 people
- Sponsor
- University of Zurich
Adenomyosis
Factors Associated With Adenomyosis and a Clinical Scoring System for the Diagnosis
Adenomyosis is a relatively common benign disorder in which endometrial gland and stroma are located within the myometrium resulting angiogenesis of the spiral vessel, hypertrophy of the surrounding smooth muscles and enlargement…
- Trial name
- NCT04830085
- Testing
- Hysterectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 221 people
- Sponsor
- Mersin University
Critical Illness
Administrative Workload in the Intensive Care Unit
A prospective observational study in the Intensive Care Unit and the Medium Care Unit in a university hospital in Amsterdam. Recent studies show that administrative tasks occupy more than 30% of the workload.
- Trial name
- AWIC (NCT02730221)
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Amsterdam UMC, location VUmc
Huntington Disease
Evaluation of Three Tests to Assess Social Cognition in Huntington Disease
The goal of this observational study is to learn about the usefulness of a test of social functioning in persons with Huntington disease.
- Trial name
- NCT07253038
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Region Skane
Gastrointestinal Hemorrhage
Glasgow-Blatschford Score Validation in Digestive Hemorrhage
The purpose of this study is to validate the Glasgow-Blatchford score for the stratification of patients with upper gastro-intestinal hemorrhage. This score is easy to calculate.
- Trial name
- NCT01029626
- Testing
- Endoscopy
- Where
- Switzerland
- Volunteers
- 208 people
- Sponsor
- University Hospital, Geneva
Advanced or Metastatic Solid Tumors, Breast Cancer
A Study of PARG Inhibitor IDE161 in Participants With Advanced Solid Tumors
The purpose of this study is to characterize the safety, tolerability, and efficacy of IDE161 as a single agent and in combination with pembrolizumab.
- Conditions
- Advanced or Metastatic Solid Tumors, Breast Cancer, Ovarian Cancer, Prostate Cancer
- Trial name
- NCT05787587
- Testing
- IDE-161, Pembrolizumab
- Where
- 27 sites in United States
- Volunteers
- 216 people
- Sponsor
- IDEAYA Biosciences
Ulcerative Colitis (UC)
The Role of CALLY and HAALP in Ulcerative Colitis
The aim of this study is to demonstrate the type and amount of retention in the colon during ulcerative colitis activation, as well as the relationship between C-reactive protein (CRP), albumin and the calculated CALLY index.
- Trial name
- NCT07236333
- Testing
- CALLY, HALP
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ataturk University
Spondylolisthesis, Lumbar Disc Herniation
Erector Spinae Plane Block as Pain Management After Lumbar Fusion Surgery
Rationale: Lumbar spine surgery is associated with high postoperative pain scores and analgesic use, despite use of multimodal analgesia.
- Conditions
- Spondylolisthesis, Lumbar Disc Herniation, Lumbar Spinal Stenosis, Lumbar Disc Disease
- Trial name
- RCT-ESPB (NCT05345249)
- Testing
- Ropivacaine Hydrochloride Injection, Sodium chloride
- Where
- Netherlands
- Volunteers
- 76 people
- Sponsor
- Ilse van de Wijgert
Bleeding
Potassium-competitive Acid Blocker Versus Double Dose Proton Pump Inhibitors in High High-risk Peptic Ulcer Bleeding
This randomized clinical trial will enroll patients at National Cheng Kung University Hospital who have upper gastrointestinal ulcer bleeding, have undergone endoscopic hemostasis, and have a Rockall score of 6 or higher.
- Trial name
- NCT07772700
- Testing
- Vonoprazon, Esomeprazole
- Volunteers
- 108 people
- Sponsor
- National Cheng-Kung University Hospital
Asthma, Bronchial
REACT - REAl Care for AsThma - A Disease Study to Identify Patients With Severe Uncontrolled Asthma
This is a multi-center, single-country, single-arm, prospective, disease study to collect real world data of patients with severe uncontrolled asthma in Germany.
- Trial name
- REACT-Asthma (NCT06299306)
- Where
- 6 sites in Germany
- Volunteers
- 19 people
- Sponsor
- AstraZeneca
Acute Appendicitis
Comparative Study on the Diagnostic Validity of the Alvarado Score, Appendicitis Inflammatory Response (AIR), and Adult Appendicitis Score (AAS) in Acute Appendicitis at East Lancashire Hospitals NHS Trust (ELHT)
This retrospective observational study aims to compare the diagnostic accuracy of Alvarado Score, Appendicitis Inflammatory Response (AIR) Score, and Adult Appendicitis Score (AAS) in predicting histologically confirmed acute…
- Trial name
- DV-AAA ELHT (NCT07804238)
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- East Lancashire Hospitals NHS Trust
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