Clinical trials: Scoring Systems
Obstructive Sleep Apnea, Difficult Intubation
STOP-BANG and Cephalometry in Prediction of Difficult Airway in Patients at Risk of OSA
Incidence of difficult laryngoscopy and difficult intubation are higher among patients with obstructive sleep apnoea (OSA). Precision in making the diagnosis and predicting difficult laryngoscopy preoperatively may help to reduce…
- Trial name
- NCT03105388
- Where
- Malaysia
- Volunteers
- 41 people
- Sponsor
- Universiti Sains Malaysia
Emergence Agitation, Pain
Emergence Agitation and Pain Scores in Pediatrics When Comparing Single-modal vs Multi-modal Analgesia for ENT Surgery
The purpose of this study is to compare the incidence of EA in pediatric patients undergoing minor ENT surgery under Sevoflurane and compare opioid-only based intra-operative analgesia to multi-modal analgesia consisting of…
- Trial name
- NCT03062488
- Testing
- IV acetaminophen, Fentanyl, PO acetaminophen
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Breast Cancer
Chemotherapy-Induced Peripheral Neuropathy - Additional Evaluation in Breast Cancer Survivors
The main goal of this trial is to identify the optimal cut-off score of a Scoring System to discriminate between mild chemotherapy-induced peripheral neuropathy (CIPN) and no CIPN in breast cancer survivors previously treated…
- Trial name
- NEURO-BREAC-02 (NCT07604441)
- Testing
- Symptom-based scoring system
- Where
- Germany
- Volunteers
- 28 people
- Sponsor
- University Hospital Schleswig-Holstein
Pain and Anxiety in Patients Undergoing Surgery for Lumbar Laminectomy.
Perioperative Melatonin in Lumbar Laminectomy
Patients undergoing lumbar laminectomy surgery will receive either 5 or 10 mg melatonin or placebo once the evening before surgery and again 90 minutes before surgery.
- Trial name
- NCT01126294
- Testing
- 5 mg melatonin, 10 mg melatonin
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- University Health Network, Toronto
Prostate Cancer
Pilot Study to Investigate Magnetic Resonance (MR) Image Guided Focal Therapy in Prostate Cancer
Background: The ability to treat early prostate cancer is still limited. Thermal ablation methods are being tested for focal prostate cancer therapy. Researchers want to improve on these methods.
- Trial name
- NCT04808427
- Testing
- TULSA-PRO
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- National Cancer Institute (NCI)
Cardiogenic Shock
ECMOsorb Trial - Impact of a VA-ECMO in Combination With CytoSorb in Critically Ill Patients With Cardiogenic Shock
In the ECMOsorb study the impact of a veno-arterial -ECMO in combination with an extracorporeal cytokine hemadsorption system in critically ill patients with cardiogenic shock is to be examined
- Trial name
- ECMOsorb (NCT05027529)
- Testing
- CytoSorb, VA-ECMO only
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- Christian Schulze
Stem Cell Transplant Complications
KIR Sequencing and Typing for Allograft in Nancy
The use of haploidentical donors for aHSCT has greatly increased this past decade leading to a major paradigm shift: while finding 10/10 HLA-matched donors represented the prior difficulty for decades, the current problem is…
- Trial name
- KIR-STAN (NCT04882605)
- Testing
- MHC typing, KIR typing, Assessment of KIR-based prediction scores
- Volunteers
- 156 people
- Sponsor
- Central Hospital, Nancy, France
Inflammatory Bowel Disease (IBD)
Comparing the Accuracy of Different Ultrasound-based Scores to Assess Disease Severity in Patients With Inflammatory Bowel Disease
Infammatory Bowel Disease (IBD) is a lifelong chronic disease comprised of two main entities: Crohn's disease and Ulcerative Colitis.
- Trial name
- NCT06705972
- Volunteers
- 60 people
- Sponsor
- Assiut University
Antisynthetase Syndrome
Descartes-08 in Autoantibody Myositis
This is a randomized, double-blind, placebo-controlled phase 2 study to evaluate the efficacy, safety and tolerability of an autologous T-cells expressing a chimeric antigen receptor (CAR) directed to B-Cell maturation antigen…
- Trial name
- NCT07391605
- Testing
- Descartes-08
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- Cartesian Therapeutics
Giant Cell Arteritis
Association of Ultrasonographic Temporal Artery Lesions and Relapse in Patients With Giant Cell Arteritis
Ultrasound evaluation of the temporal and axillary arteries is currently well recognized in the field of giant cell arteritis (GCA), a disease primarily affecting medium- and large-caliber vessels.
- Trial name
- ALERT (NCT06894602)
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Brest
Digestive System Disease
CONECCT (Colorectal Neoplasia Endoscopic Classification To Chose the Endoscopic Treatment)
Prospective study so as to evaluate CONECCT score to determine both histological tissue and therapeutic choice
- Trial name
- NCT03455595
- Testing
- Endoscopic exams
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Hôpital Edouard Herriot
Sleep-Wake Disorders, Healthy
Validation of Non-invasive Miniature Optical Sensors for Scoring Sleep Stages
Validation of two devices with optical sensor in healthy participants and patients with sleep wake disorders.
- Trial name
- NCT03823105
- Testing
- OHR Tracker and PulseWatch
- Where
- Switzerland
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Sigmoid Cancer, Sigmoid Diverticulosis
Comparison of Quality of Life and Functionnal Resultats After Sigmodectomy Between Diverticulitis and Cancer
The aim of this present study is to compare functional results and quality of life after sigmoidectomy for diverticulitis and sigmoid cancer.
- Trial name
- SIG-QOL (NCT04729283)
- Testing
- Sigmoidectomy
- Where
- 4 sites in France
- Volunteers
- 94 people
- Sponsor
- Nantes University Hospital
Fecal Impaction, Lower Urinary Tract Disorder
Development of Fecal Scoring for the Management of Fecal Impaction With Regards to Lower Urinary Tract Dysfunction
The role of bowel bladder disorder, or BBD, has been highlighted as a major player in vesicoureteral reflux and urinary tract infection (UTI).
- Conditions
- Fecal Impaction, Lower Urinary Tract Disorder, Bladder Dysfunction, Bowel Dysfunction
- Trial name
- NCT04579731
- Testing
- Lactitol Monohydrate
- Where
- South Korea
- Volunteers
- 187 people
- Sponsor
- Seoul National University Hospital
Critically Ill Patients
Pain Measurement and Pain Management in the Intensive Care Unit(ICU)
The purpose of this study is to evaluate the effect of a pain training program and systematic measurement of pain scores on actual pain levels and the use of analgesics in critically ill patients.
- Trial name
- PIJNICU2 (NCT00773045)
- Testing
- A Pain training program and pain measurement
- Volunteers
- 190 people
- Sponsor
- St. Antonius Hospital
Coronary Artery Disease, Atherosclerosis, Coronary
HIV Infection And Evolvement of Atherosclerotic Plaque
In a prospective multi-center observational study, 200 HIV-infected patients treated with antiretroviral treatment (ART) and who suffered from coronary artery disease (CAD) will be enrolled.
- Conditions
- Coronary Artery Disease, Atherosclerosis, Coronary, Hiv, HIV Infections
- Trial name
- HIVE (NCT04810364)
- Testing
- Quantitative coronary angiography, intravascular imaging with percutaneous intervention
- Where
- 2 sites in Russia
- Volunteers
- 1,000 people
- Sponsor
- Central Clinical Hospital of the Russian Academy of Sciences
Prediabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
Pharmacists' Delivery of Education to Prevent Diabetes in the New Orleans Hospitality Industry
This is a one-year pilot study focused on prediabetes among hospitality workers in New Orleans, Louisiana. The project will assess prediabetes rates among the target population, evaluate the impact of pharmacist led lifestyle…
- Conditions
- Prediabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Prediabetic State &Amp; High Risk Individuals on the Basis of Diabetes Risk Score
- Trial name
- NCT07451314
- Testing
- Linkage to Care, Educational, Healthy Lifestyle Tools
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Xavier University of Louisiana.
Syncope
SW-RCT Implementation of Canadian Syncope Risk Score Based Practice Recommendations
Syncope is a common reason for emergency department (ED) presentation. While often benign, some patients have serious and life-threatening underlying causes, both cardiac and non-cardiac, which may or may not be apparent at the…
- Trial name
- NCT04972071
- Testing
- Knowledge translation (KT) of the CSRS based practice recommendations
- Where
- 15 sites in Canada
- Volunteers
- 14,400 people
- Sponsor
- Ottawa Hospital Research Institute
Advanced or Metastatic Solid Tumors, Breast Cancer
A Study of PARG Inhibitor IDE161 in Participants With Advanced Solid Tumors
The purpose of this study is to characterize the safety, tolerability, and efficacy of IDE161 as a single agent and in combination with pembrolizumab.
- Conditions
- Advanced or Metastatic Solid Tumors, Breast Cancer, Ovarian Cancer, Prostate Cancer
- Trial name
- NCT05787587
- Testing
- IDE-161, Pembrolizumab
- Where
- 27 sites in United States
- Volunteers
- 216 people
- Sponsor
- IDEAYA Biosciences
Rheumatoid Arthritis (RA)
Validation of the Synovo Digital Disease Activity Score (DDAS) Against Physician-Performed DAS28/CDAI: A Non-Clinical, Non-Interventional, Non-Academic Study
The goal of this observational study is to assess whether the Synovo digital assessment can measure rheumatoid arthritis disease activity in adults with rheumatoid arthritis.
- Trial name
- DDAS accuracy (NCT07740200)
- Testing
- Digital Disease Activity Assessment
- Where
- Pakistan
- Volunteers
- 61 people
- Sponsor
- Synovo Ltd.