Clinical trials: Scoring Systems
Chronic Spontaneous Urticaria
Study of Efficacy and Safety of Ligelizumab in Chronic Spontaneous Urticaria Patients Who Completed a Previous Study With Ligelizumab
The purpose of this extension study was to establish efficacy and safety of ligelizumab. This was assessed in adult and adolescent chronic spontaneous urticaria (CSU) patients who had completed a preceding ligelizumab study and…
- Trial name
- NCT04210843
- Testing
- Ligelizumab
- Where
- 273 sites in United States, Argentina and 43 more
- Volunteers
- 1,033 people
- Sponsor
- Novartis Pharmaceuticals
Congenital Heart Disease
Comparison of PRISM III, PIM2 and PELOD Scoring Systems
PRISMIII(Pediatric Risk of Mortality III), PIM2(Pediatric Index of Mortality 2) and PELOD(Pediatric Logistic Organ Dysfunction) are frequently used for predicting mortality and morbidity in general pediatric ICUs(Intensive Care…
- Trial name
- NCT04848168
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people
- Sponsor
- Antalya Training and Research Hospital
Acute Appendicitis
Sensitivity and Specificity of the Alvarado Score for the Timely Differential Diagnosis of Acute Appendicitis in Samoa
Retrospective clinical data review design of all patients admitted to the Tupua Tamasese Meaole Hospital Surgical Unit for AA from January 2015 to December 2016.
- Trial name
- NCT05168410
- Testing
- Alvarado Score
- Volunteers
- 225 people
- Sponsor
- Dr Annette Kaspar
Minor/Mild Traumatic Brain Injury
S100 Protein in Minor/Mild Traumatic Brain Injury
Traumatic brain injury (TBI) is a Public Health problem, because of the numbers of events (more than 200,000 per year in France).
- Trial name
- S100 (NCT00822445)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Gastric Cancer
Multi-Omics Noninvasive Inspection of TumOr Risk for Gastric Cancer
This is a prospective, case-control study intended to develop and validate a blood-based multi-omics assay and computational model for early detection of gastric cancer.
- Trial name
- MONITOR- GAC (NCT04947995)
- Testing
- ctDNA multi-omics test
- Where
- China
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- GeneCast Biotechnology Co., Ltd.
Vitiligo
Virus Early Transcription Factor (VETF) Multicenter Phototherapy Protocol
Background Phototherapy UVB TL01 currently represents the first choice in treatment to induce the repigmentation of vitiligo spots.
- Trial name
- VETF (NCT00525395)
- Testing
- Sequential phototherapy, Continuous phototherapy
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Istituti Fisioterapici Ospitalieri
Hepatocellular Carcinoma, Portal Vein Thrombosis
Surgical Outcome of HCC With Portal Vein Tumor Thrombosis on the Basis of Risk Scoring
The goal of this multicenter retrospective cohort study is to investigate the clinical outcomes and prognostic factors after hepatic resection in patients with HCC exhibiting PVTT, and to develop a prognostic index that can be…
- Conditions
- Hepatocellular Carcinoma, Portal Vein Thrombosis, Prognosis
- Trial name
- NCT06005883
- Where
- South Korea
- Volunteers
- 332 people
- Sponsor
- Keimyung University Dongsan Medical Center
Neuropathic Pain, Diabetes
Study to Evaluate the Efficacy and Safety of DS-1971a for the Treatment of Diabetic Peripheral Neuropathic Pain (DPNP)
The hypothesis of this Phase 2 study is that at least 1 dose regimen of DS-1971a will demonstrate clinical superiority to placebo in managing pain associated with DPNP, and will be generally well tolerated.
- Trial name
- NCT02673866
- Testing
- DS-1971a, pregabalin
- Sponsor
- Daiichi Sankyo
Painful Diabetic Neuropathy
Safety and Efficacy of EMA401 in Patients With Painful Diabetic Neuropathy (PDN)
The purpose of this study is to evaluate safety and efficacy of EMA401 compared to placebo in patients with painful diabetic neuropathy (PDN).
- Trial name
- EMPADINE (NCT03297294)
- Testing
- EMA401
- Where
- 64 sites in Australia, Austria and 14 more
- Volunteers
- 142 people
- Sponsor
- Novartis Pharmaceuticals
Nonalcoholic Fatty Liver, Nonalcoholic Steatohepatitis
Prevalence of NAFLD and Advanced Fibrosis in Patients With Type 1 Diabetes
The aim of this study is to assess the prevalence of nonalcoholic fatty liver disease (NAFLD) in patients with type 1 diabetes receiving care at Joslin clinic using noninvasive imaging and serum-based methods with the goal of…
- Conditions
- Nonalcoholic Fatty Liver, Nonalcoholic Steatohepatitis, Fibrosis, Liver, Type 1 Diabetes
- Trial name
- NCT04595474
- Testing
- Transient Elastography
- Where
- United States
- Volunteers
- 533 people
- Sponsor
- Joslin Diabetes Center
Sepsis Syndrome, Emergency Department
Can we Improve Mortality Prediction in Patients With Sepsis in the Emergency Department
This study aims to identify the prognostic role of procalcitonin (PCT), soluble Triggering Receptor Expressed on Myeloid Cells-1 (sTREM-1), the soluble form of the urokinase plasminogen activator receptor (suPAR), highly…
- Conditions
- Sepsis Syndrome, Emergency Department, Biomarker
- Trial name
- NCT06338111
- Testing
- ELISA Sepsis Biomarkers dosage
- Where
- Romania
- Volunteers
- 67 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Cerebral Palsy, Gait Disorders in Children
Gait Profile Score in Children With Cerebral Palsy (CP): Influence of the CP Type, Treatment With Botulinum Injection and Multilevel Surgery
Instrumented three dimensional gait analysis (3DGA) permits to record spatial, temporal, kinetics, kinematics and electromyographic (EMG) parameters in order to understand gait impairment in children and teenagers with cerebral…
- Trial name
- NCT06505499
- Testing
- Gait Profile Score, Gait Visual Score
- Where
- France
- Volunteers
- 51 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Rectal Adenocarcinoma, LARS - Low Anterior Resection Syndrome
ProLARS Trial: Prospective Longitudinal Follow-up of Low Anterior Resection Syndrome (LARS) and COREFO Score After Rectum Surgery in Patients Undergoing Upfront Surgery or Different Neo-adjuvant Treatment Regimens
OBJECTIVE Low anterior resection syndrome (LARS) is a term for functional bowel complaints occurring after low anterior resection.
- Conditions
- Rectal Adenocarcinoma, LARS - Low Anterior Resection Syndrome, Rectal Resection, Low Anterior Resection
- Trial name
- ProLARS (NCT07339904)
- Testing
- Questionnaire
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University Hospital, Antwerp
Fracture Non Union
Validity of the Non-union Scoring System in Management of Long Bone Fracture Non-union
The aim of this study is to apply Calori Non union Scoring System on long bone non-union cases and evaluate the results of treatment o f the patients according to the score.
- Trial name
- NCT07207447
- Testing
- Improving the stability and re-fixation with different modalities, Re-fixation with biological stimulation, complex care with non-union resection and bone reconstruction
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Seasonal Allergic Rhinitis
Study to Assess the Effect of a Combination of Cetirizine With Pseudoephedrine Versus Cetirizine Alone on Symptoms in Patients With Allergic Rhinitis
The aim of this study is to assess the efficacy on nasal congestion and other allergic symptoms and the onset of action of an oral combination of cetirizine and pseudoephedrine in comparison to the single substances under…
- Trial name
- NCT00334698
- Testing
- Cetirizine, Pseudoephedrine, Cetirizine with Pseudoephedrine
- Where
- Germany
- Volunteers
- 51 people
- Sponsor
- Fraunhofer-Institute of Toxicology and Experimental Medicine
Sleep Apnea, Obstructive
Influence of Different Methods of Measurement in the Accuracy of DES-OSA and P-SAP Scores
DES-OSA and P-SAP scores have been validated to detect OSA (Obstructive Sleep Apnea). One item of P-SAP and DES-OSA is the measurement of neck circumference.
- Trial name
- NCT03047421
- Testing
- Comparison of accuracy of DES-OSA and P-SAP scores
- Where
- Belgium
- Volunteers
- 1,682 people
- Sponsor
- Astes
Syncope
Canadian Prehospital Syncope Risk Score (Prehospital CSRS)
Background: Syncope is defined as a sudden, brief loss of consciousness (LOC) followed by a rapid complete recovery. It accounts for 160,000 emergency department (ED) visits each year in Canada.
- Trial name
- NCT05560126
- Where
- Canada
- Volunteers
- 4,875 people
- Sponsor
- Venkatesh Thiruganasambandamoorthy
Ulcerative Colitis
A Study Evaluating The Efficacy And Safety Of CP-690,550 In Patients With Moderate To Severe Ulcerative Colitis
This study is designed to evaluate the efficacy and safety of tofacitinib (CP-690,550) in patients with moderate to severe ulcerative colitis who have failed or be intolerant to one of following treatments for ulcerative colitis…
- Trial name
- OCTAVE (NCT01465763)
- Testing
- tofacitinib
- Where
- 178 sites in United States, Australia and 26 more
- Volunteers
- 614 people
- Sponsor
- Pfizer
Colonoscopy
A Clinical Validation Study of a Computerized Movement Analysis of the Colonoscope
Colonoscopy is the considered gold standard for diagnosing diseases in the colon. A colonoscopy is normally divided into the insertion from anus to cecum, the technical difficult part, and a retraction or diagnostic part.
- Trial name
- NCT03587935
- Testing
- 3D-Colonoscopy Progression Score, 3D-Colonoscopy Retraction Score
- Where
- Denmark
- Volunteers
- 9 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Seasonal Allergic Rhinitis
Comparison of the Effects of Desloratadine and Placebo in the Relief of Nasal Symptom Scores in Subjects With Seasonal Allergic Rhinitis to Cypress Pollen (Study P02836)
The purpose of this study was to demonstrate the efficacy (% of change from baseline) of desloratadine to improve the nasal total symptom score of SAR to cypress pollen.
- Trial name
- NCT00867191
- Testing
- Desloratadine
- Volunteers
- 233 people
- Sponsor
- Organon and Co
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