Clinical trials: Scoring Systems
Pelvic Organ Prolapse, Prolapse
A New POP (Pelvic Organ Prolapse) Scoring System: Validity and Reliability
There is a strong need for a better, simplified and informative applicable classification system that should be used to speak a common descriptive language among health care providers that treat POP.
- Conditions
- Pelvic Organ Prolapse, Prolapse, Prolapse, Vaginal, Prolapse Uterus
- Trial name
- NCT06520722
- Testing
- Prolapse scoring system
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Cairo University
Preterm Birth
Effectiveness of Targeted Cervical Length Screening Guided by a Preterm Birth Risk Scoring System in Reducing the Rate of Preterm Birth
This cluster non-randomized controlled trial aims to evaluate the effectiveness and feasibility of a risk score-guided targeted cervical length screening strategy for the prevention of spontaneous preterm birth in routine…
- Trial name
- NCT07415070
- Testing
- Preterm birth risk scoring system, Transvaginal ultrasound cervical length measurement, Vaginal Progesterone
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Ningbo University
Rheumatoid Arthritis
SMART Study: A Study of Re-treatment With MabThera (Rituximab) in Patients With Rheumatoid Arthritis Who Have Failed on Anti-TNF Alfa Therapy
This study will compare the efficacy and safety of re-treatment with 2 doses of MabThera (rituximab) in patients with active rheumatoid arthritis (RA) who have previously experienced an inadequate response or intolerance to…
- Trial name
- NCT01126541
- Testing
- rituximab
- Where
- 53 sites in France
- Volunteers
- 224 people
- Sponsor
- Hoffmann-La Roche
Pulmonary Atelectasis
Effect of Recruitment Maneuver on Postoperative Atelectasis Assessed by Lung Ultrasound in Laparoscopic Cholecystectomy
This single-centre, prospective, randomized, parallel-group controlled trial evaluated whether alveolar recruitment manoeuvres (RMs) added to a lung-protective ventilation strategy improve perioperative lung aeration in adults…
- Trial name
- LUNG USG SCORE (NCT07324122)
- Testing
- Alveolar recruitment manoeuvre, Lung-protective ventilation with lung ultrasound assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Inflammatory Myopathy, Idiopathic, Dermatomyositis
Add-on Intravenous Immunoglobulins in Early Myositis
In patients with myositis early immunomodulation by intensive treatment ("hit-early/hit-hard" principle) may induce faster reduction of disease activity and prevent chronic disability.
- Conditions
- Inflammatory Myopathy, Idiopathic, Dermatomyositis, Antisynthetase Syndrome, Immune-Mediated Necrotizing Myopathy
- Trial name
- TIMEISMUSCLE (NCT05832034)
- Testing
- Immune Globulin Intravenous (Human)
- Where
- Netherlands
- Volunteers
- 44 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Lung Cancer
Pneumonitis After Radiotherapy for Lung Cancer
Major goals of radiotherapy include local disease control and improvement of the patients' prognoses. One possible side effect of radiotherapy for lung cancer is radiation pneumonitis.
- Trial name
- PARALUC (NCT04335409)
- Testing
- Questionnaire, Mobile Application
- Where
- Germany
- Volunteers
- 57 people
- Sponsor
- University Hospital Schleswig-Holstein
Hospital Rapid Response Team, Hospital Medical Emergency Team
Deep Learning Based Early Warning Score in Rapid Response Team Activation
The objective of this study is to evaluate the safety and clinical usefulness of the Deep learning based Early Warning Score (DEWS).
- Trial name
- NCT04951973
- Testing
- Deep Learning Based Early Warning Score (DEWS)
- Volunteers
- 50,000 people
- Sponsor
- Seoul National University Hospital
Low Anterior Resection Syndrome
International Low Anterior Resection Score Evaluation
Aim: The aim of this study is to perform a prospective, international 4 months cohort study evaluating bowel function before curative rectal cancer surgery and one year after the surgery using the LARS score.
- Trial name
- PrePostLARS (NCT04040842)
- Testing
- Patients undergoing low anterior resection
- Where
- Lithuania
- Volunteers
- 400 people
- Sponsor
- National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos
Brain Injury
Criteria of Extubation Failure of Brain Injured Patients. Elaboration of a Prognostic Score.
Identification of criteria associated with extubation failure of brain injured patients. Elaboration of a prognostic score of extubation failure of brain injured patients.
- Trial name
- GODWEAN (NCT02235376)
- Testing
- weaning trial of mechanical ventilation
- Where
- France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Clermont-Ferrand
Postoperative Delirium
Naples Prognostic Score for Predicting Postoperative Delirium
Naples Prognostic Score (NPS) originally developed to predict outcomes in inflammatory and malignant conditions; we asked if it can effectively predict postoperative delirium (POD) in elderly patients undergoing hip surgery? NPS…
- Trial name
- NCT07297017
- Where
- Egypt
- Volunteers
- 168 people
- Sponsor
- South Valley University
Cardiovascular Disease Prevention, Cardiometabolic Diseases
Preventative Screening and Health Coaching in a Food Insecure Population
The goal of this longitudinal study is to investigate the role of virtual health coaching on mitigation of cardiometabolic disease risk in an underserved, food insecure population.
- Conditions
- Cardiovascular Disease Prevention, Cardiometabolic Diseases, Cardiovascular Risk Factor, Cardiovascular Risk Score
- Trial name
- HEALTHCOACH (NCT06907524)
- Testing
- Longitudinal, Individualized Health Coaching
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Rush University Medical Center
Obesity
Evaluation of Liver Fibrosis Following Surgical-induced Weight Loss
Obesity is a frequent disease with an increased prevalence, estimated to 12.4% in France (OBEPI study 2006). Non alcoholic fatty liver disease (NAFLD) and non alcoholic steatohepatitis (NASH) both complicate morbid obesity and…
- Trial name
- FIBROTEST (NCT01469962)
- Testing
- Surgical procedure
- Where
- France
- Volunteers
- 255 people
- Sponsor
- University Hospital, Rouen
Antisynthetase Syndrome
Descartes-08 in Autoantibody Myositis
This is a randomized, double-blind, placebo-controlled phase 2 study to evaluate the efficacy, safety and tolerability of an autologous T-cells expressing a chimeric antigen receptor (CAR) directed to B-Cell maturation antigen…
- Trial name
- NCT07391605
- Testing
- Descartes-08
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- Cartesian Therapeutics
Neuropathic Pain
Observational Study Aimed at Evaluating the Trend of Neuropathic Pain
The present study aims to evaluate the trend of neuropathic pain in patients treated with Peacetil for a period of two months. Neuropathic pain will me assessed through the Numeric Rating Scale (NRS) questionnaire score.
- Trial name
- NEURATIL (NCT06324123)
- Testing
- Peacetil
- Where
- 3 sites in Italy
- Volunteers
- 122 people
- Sponsor
- Istituto Auxologico Italiano
MASLD, T2DM (Type 2 Diabetes Mellitus)
Non-Invasive MASLD Diagnosis & T2D Remission Biomarkers
The goal of this observational study is to prospectively develop and validate a non-invasive scoring system based on metabolic markers, proteomic, and transcriptomic profiles to accurately screen, diagnose, stage, and monitor…
- Conditions
- MASLD, T2DM (Type 2 Diabetes Mellitus), Non-alcoholic Fatty Liver Disease (NAFLD), Obesity
- Trial name
- ENSURE-MASLD (NCT07172997)
- Testing
- Bariatric Surgery
- Where
- 2 sites in Bahrain
- Volunteers
- 163 people
- Sponsor
- Royal College of Surgeons in Ireland - Medical University of Bahrain
Rheumatoid Arthritis
Venlafaxine as Adjunct Therapy in Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent inflammation of the joints, leading to pain, swelling, disability, and reduced quality of life.
- Trial name
- NCT07497282
- Testing
- venlafaxine extended-release (XR), Standard conventional Rheumatoid Arthritis Therapy
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Liver Cirrhosis
Fecal Microbiota Transplantation in Decompensated Cirrhosis
Cirrhosis of the liver is the culmination point of long-standing chronic liver disease hallmarked by the cardinal features of liver fibrosis and portal hypertension.
- Trial name
- NCT04842539
- Testing
- Fecal Microbiota Transplantation, Standard of care
- Where
- India
- Volunteers
- 36 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Acute ST Segment Elevation Myocardial Infarction
ABSORB STEMI: the TROFI II Study
This is a Prospective, randomized (1:1), active control, single-blind, non-inferiority, European multicenter clinical trial. The primary objective of this study is to assess the neointimal healing score (as evaluated by…
- Trial name
- NCT01986803
- Testing
- Percutaneous Coronary Intervention
- Where
- 8 sites in Denmark, Netherlands and 2 more
- Volunteers
- 191 people
- Sponsor
- ECRI bv
Cholecystitis, Chronic
A Scoring System for Difficult Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is the treatment of choice for gall bladder stone disease. Difficult laparoscopic cholecystectomy (LC) is the most common "difficult" surgical procedure performed today, which possesses the potential…
- Trial name
- NCT04569370
- Testing
- Laparoscopic Cholecystectomy
- Volunteers
- 100 people
- Sponsor
- Assiut University
Pancreatic Carcinoma; Lipoprotein a; Overall Survival; Prognosis
Lipoprotein a is an Independent Risk Factor for Overall Survival in Patients With Pancreatic Cancer: a Propensity Score Matching Analysis
Background: This study aims to assess the prognostic significance of serum lipoprotein (a) [Lp (a)] levels on overall survival (OS) and progression free survival (PFS) in individuals diagnosed with pancreatic cancer through the…
- Trial name
- NCT06316466
- Testing
- Lp(a)
- Where
- China
- Volunteers
- 360 people
- Sponsor
- jingxue