Clinical trials: Screening
Obesity, Heart Failure
Screening Adults With Obesity to Reduce Heart Failure Events
Rationale: Obesity prevalence in Dutch adults increased to 14.2% in 2020. Obesity is strongly associated with cardiovascular disease, especially heart failure (HF).
- Trial name
- SCOR(hf)E (NCT06137261)
- Testing
- Screening for heart failure
- Where
- Netherlands
- Volunteers
- 420 people
- Sponsor
- Franciscus Gasthuis
Hepatitis C, Testing
Community Versus Facility-based Services to Improve the Screening of Active HCV Infection in Cambodia
Objectives Principal objective: to compare the effectiveness of a community-based intervention to a facility-based intervention to improve the combined-testing uptake (Antibody + RNA) of HCV infection among general population…
- Trial name
- Cam-C (NCT03992313)
- Testing
- Community-based HCV rapid test, Facility-based HCV rapid test, Plasmatic HCV viral load
- Where
- 2 sites in Cambodia
- Volunteers
- 7,692 people, healthy volunteers welcome
- Sponsor
- ANRS, Emerging Infectious Diseases
Diabetic Retinopathy
Diabetic Retinopathy and Diabetic Macular Edema Screening by Non-Physicians With Limited Training
The purpose is to assess accuracy of digital retinal image interpretation by technicians and direct ophthalmoscopy by nurses for the determination of diabetic retinopathy severity and the presence of diabetic macular edema for…
- Trial name
- NCT00500097
- Testing
- Digital retina image, direct ophthalmoscopy, comprehensive eye exam
- Where
- Thailand
- Volunteers
- 840 people
- Sponsor
- Ministry of Health, Thailand
AIDS, HIV Seropositivity
Investigation of the Psychosocial Factors Responsible for the Late Recourse to HIV Testing Within MSM
The present study will try to investigate and analyze the psycho-social hindrances and levers concerning the recourse to late HIV testing among the MSM population. This study is divided in two parts.
- Trial name
- ReTarD (NCT03661203)
- Testing
- Focus group, Individual interview, online self questionnaire
- Where
- 4 sites in France
- Volunteers
- 1,190 people
- Sponsor
- French National Agency for Research on AIDS and Viral Hepatitis
Cervical Cancer
SUCCESS - Feasibility of HPV Testing and Treatment of Pre-cancerous Cervical Cancer Lesions (HPV Study)
The goal is to assess the feasibility and acceptability of integrating into existing health systems, provision of HPV screening and treatment of pre-cancerous cervical cancer lesions with ablative treatments in Burkina Faso, Côte…
- Trial name
- HPV (NCT05133661)
- Testing
- HPV testing
- Where
- 4 sites in Burkina Faso, Côte d’Ivoire and 2 more
- Volunteers
- 17,602 people, healthy volunteers welcome
- Sponsor
- Jhpiego
Premature Labour
Prevention and Treatment of Premature Labour for Asymptomatic Pregnant Women
State of the question and research objective: International trials have shown that ultrasound measurement of the cervix identifies a population at high risk of preterm delivery.
- Trial name
- Echo-col (NCT02598323)
- Testing
- ultrasound
- Where
- France
- Volunteers
- 3,500 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Breast Neoplasms
Early Detection of Breast Cancer
The TriNetra™ Breast test is intended for use as a breast cancer screening test that evaluates Circulating Tumor Cells (CTCs) associated with breast cancer.
- Trial name
- NCT06043661
- Where
- United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Datar Cancer Genetics Inc
Colorectal Cancer, Satisfaction, Patient
Shared Decision Making and Satisfaction With the Diagnostic-therapeutic Process in the Shared Decision Making and Satisfaction With Colorectal Cancer Screening. The CyDESA Study
A cross sectional multicenter study (3 centers) to know the participation in decision making and the experience and satisfaction of participants with a positive immunological fecal test (FIT) result in relation to the screening…
- Trial name
- CyDESA (NCT04610086)
- Where
- Spain
- Volunteers
- 846 people
- Sponsor
- Corporacion Parc Tauli
Preterm Birth
Transvaginal Ultrasound Cervical Length Screening in Singleton Pregnancy With Prior Spontaneous Preterm Birth
Preterm birth (PTB) is the major cause of perinatal morbidity and mortality. Worldwide, about 15 million babies are born too soon every year, causing 1.1 million deaths, as well as short- and long-term disability in countless…
- Trial name
- NCT02923973
- Testing
- Transvaginal ultrasound cervical length screening
- Where
- 2 sites in Italy
- Volunteers
- 500 people
- Sponsor
- Federico II University
Endovascular Thrombectomy
Medical Imaging Screening for Posterior-circulation Ischemic Stroke
Patients with ischemic stroke in the posterior circulation continue to have high rates of mortality and disability, even with aggressive treatment.
- Trial name
- NCT06094569
- Testing
- Endovascular Therapy
- Where
- 4 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Tianjin Huanhu Hospital
Health Knowledge, Attitudes, Practice, Alcohol Drinking
An Electronic Brief Alcohol Intervention for Women Attending a Breast Screening Service (Health4Her)
Alcohol is a major modifiable risk factor for female breast cancer; yet, awareness of this risk remains surprisingly low and is not systematically addressed in healthcare settings.
- Trial name
- NCT06019442
- Testing
- Brief alcohol intervention (Health4Her-Automated), Lifestyle health promotion
- Where
- Australia
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Turning Point
Advanced Colorectal Neoplasms, Throat Cancer
Fecal Screening Assay for Taiwanese Population
Fecal occult blood test (FOBT) is a convenient tool for the screening of asymptomatic gastrointestinal (GI) bleeding while 「guaiac-based fecal occult test (G-FOBT) 」 is increasingly replaced by the use of an 「immunochemical-based…
- Conditions
- Advanced Colorectal Neoplasms, Throat Cancer, Esophageal Cancer, Gastric Cancer
- Trial name
- NCT01341197
- Testing
- Fecal immunochemical test, guaiac fecal occult-blood test, and Helicobacter pylori stool antigen test
- Where
- Taiwan
- Volunteers
- 3,172 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Colorectal Carcinoma
Addressing Disparities in Colorectal Cancer Screening in Black and Underserved Phoenix Communities
This clinical trial studies disparities involving colorectal cancer prevention and screening in Black and underserved communities in the Phoenix metropolitan area.
- Trial name
- NCT05447923
- Testing
- Educational Intervention, Fecal Immunochemical Test, Patient Navigation
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Bone Marrow Transplant, Sickle Cell Disease
Screening for Subjects to Participate in Studies of Blood Disorders
This study will determine eligibility for participation in research studies on blood disorders conducted by the National Heart, Lung and Blood Institute and the National Institute of Diabetes, Digestive, and Kidney Diseases.
- Conditions
- Bone Marrow Transplant, Sickle Cell Disease, G-CSF
- Trial name
- NCT00695123
- Where
- United States
- Volunteers
- 816 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
HIV - Human Immunodeficiency Virus, HBV (Hepatitis B Virus)
MAGIA H3S Point of Care Test Performance for HIV, HBV, HCV, and Syphilis Screening in Pregnant Women in DR Congo
Performance study to evaluate the clinical performance of the In-Vitro Diagnostic Medical Device MagIA H3S (a Multiplex Point-of-Care test for the combined detection of Human Immunodeficiency Virus (HIV), Hepatitis B and C and…
- Conditions
- HIV - Human Immunodeficiency Virus, HBV (Hepatitis B Virus), Hepatitis C Virus (HCV), Syphilis
- Trial name
- MAGICS MAM (NCT07388979)
- Testing
- MAGIA H3S
- Volunteers
- 7,500 people, healthy volunteers welcome
- Sponsor
- Gardiens de Vies
Diabetic Retinopathy
Artificial Intelligence for Diagnosing Diabetic Retinopathy in Primary Care
This is a clinical trial to evaluate the effects of universal screening for diabetic retinopathy (DR) and diabetic macular edema (DME) using artificial intelligence (AI) in the interpretation of fundus photographs obtained by…
- Trial name
- AID-DR (NCT07236879)
- Testing
- Mobile retinography interpreted by artificial intelligence, Mobile retinography interpreted by ophthalmologists
- Where
- Brazil
- Volunteers
- 922 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Cervical Cancer Screening, Cervical Cancer
Using Artificial Intelligence-based ChatBot to Improve Women's Participation to Cervical Cancer Screening Programme
This project looks to improve the return rate of HPV self-sampling (HPVss) as well as the management of women HPVss positive.
- Trial name
- AppDate-You (NCT05286034)
- Testing
- Decision aid tailored to women with lower educational attainment,accessible via artificial intelligence-based Chatbot platforms
- Where
- France
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- International Agency for Research on Cancer
Participation Rate, Patient
Telephone Services for Participation in Colorectal Cancer Screening
A multicentre randomized health services study within the population-based primary colonoscopy screening program (PCSP) in Poland.
- Trial name
- ColoPhone (NCT04348058)
- Testing
- Telephone recruitment to screening colonoscopy, Combined methods recruitment to screening colonoscopy
- Where
- Poland
- Volunteers
- 6,300 people
- Sponsor
- Maria Sklodowska-Curie National Research Institute of Oncology
HIV Infections, Lipodystrophy
Underlying Abnormalities in Fat and Muscle Leading to Lipodystrophy Syndrome
With the advent of highly active anti-retroviral therapy(HAART), patients with HIV disease are developing a series of metabolic abnormalities including peripheral fat wasting, increase in truncal fat, high serum triglyceride…
- Conditions
- HIV Infections, Lipodystrophy, Insulin Resistance
- Trial name
- NCT00006185
- Testing
- Avandia administration for 6-12 weeks
- Where
- United States
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Tuberculosis
Tuberculosis Diagnostic Trial of CAD4TB Screening Alone Compared to CAD4TB Screening Combined With a CRP Triage Test, Both Followed by Confirmatory Xpert MTB/RIF Ultra in Communities of Lesotho and South Africa
According to WHO, about 40% of the incident TB cases in 2020 are either under-reported or under-diagnosed causing on one hand major health risks and on the other hand catastrophic financial consequences.
- Trial name
- NCT05526885
- Testing
- CAD4TB, POC-CRP, Xpert MTB/RIF Ultra
- Where
- 2 sites in Lesotho, South Africa
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Klaus Reither