Clinical trials: Screening Colonoscopies, open to volunteers
Colonic Neoplasms
Artificial Intelligence to Implement Cost-saving Strategies for Colonoscopy Screening Based on in Vivo Prediction of Polyp Histology
This three parallel-arms, randomized, multicenter trial is aimed at investigating the value of AI-assisted optical biopsy for differentiating between neoplastic and non-neoplastic polyps which will lead to the implementation of…
- Trial name
- SAVE (NCT06041945)
- Testing
- Standard, high-definition colonoscopy with the use of CADe assistance, Standard, high-definition colonoscopy with the use of CADe/CADx assistance, no leave-in-situ, Standard, high-definition colonoscopy with the use of CADe/CADx assistance, leave-in-situ
- Where
- 2 sites in Italy
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Colon Cancer
Building Capacity for Screening & Early Diagnosis of Colorectal Cancer Through a Comprehensive Colonoscopy Training Program in Nigeria
This protocol seeks to develop a colonoscopy training program in Nigeria in order to increase the number of health care providers proficient in colonoscopy.
- Trial name
- NCT05686499
- Testing
- Didactic Lectures and demonstrations
- Where
- 2 sites in Nigeria
- Volunteers
- 20 people
- Sponsor
- Obafemi Awolowo University Teaching Hospital
Breast Cancer Screening, Colon Cancer Screening
Bundled Cancer Screening and Genetic Services Navigation
The goal of this study is to test bundled familial cancer risk assessment + multicancer (colorectal + breast) vs. single (breast) cancer navigation, using a wait list control for colorectal cancer screening referral and…
- Conditions
- Breast Cancer Screening, Colon Cancer Screening, Genetics Predisposition
- Trial name
- NCT07228000
- Testing
- Breast cancer screening navigation, Multicancer screening navigation, Usual care genetics referral
- Where
- 2 sites in United States
- Volunteers
- 820 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Colorectal Neoplasms, Colonic Polyps
Evaluation of Versatile Intelligent Staining Technology (VIST) and Spectral Flexible Imaging (SFI) for Detection and Optical Characterization of Colorectal Lesions: A Prospective Randomized Controlled Study
This prospective randomized controlled study aims to evaluate the diagnostic accuracy of Versatile Intelligent Staining Technology (VIST) and Spectral Flexible Imaging (SFI) for detection and optical characterization of…
- Conditions
- Colorectal Neoplasms, Colonic Polyps, Adenoma, Serrated Polyps
- Trial name
- INSIGHT (NCT07797361)
- Testing
- White Light Endoscopy, Versatile Intelligent Staining Technology, Spectral Flexible Imaging
- Where
- Brazil
- Volunteers
- 990 people
- Sponsor
- Alexandre Vontobel Padoin
Cancer Screening, Chronic Diseases in Older Adults
Pragmatic Mobile Health Trial to Promote Cancer Screening and Healthy Behaviors
Cancer is the leading cause of death in Singapore, but many people who are eligible for breast, cervical, and colorectal cancer screening do not get screened on time.
- Conditions
- Cancer Screening, Chronic Diseases in Older Adults, Early Cancer Detection, Mammography
- Trial name
- mHEALTH (NCT07725328)
- Testing
- Intensive Engagement, Standard Engagement
- Where
- Singapore
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Colorectal Cancer Early Detection
Efficacy and Tolerability of a Simethicone-containing Evacuating Solution for Colorectal Cancer Screening Colonoscopy
Study to evaluate the efficacy and tolerability of a simethicone-containing evacuating solution for colorectal cancer screening colonoscopy.
- Trial name
- CLEAN+ (NCT07696793)
- Testing
- Clensia®, Citrafleet®
- Where
- Spain
- Volunteers
- 818 people
- Sponsor
- Fundacion Clinic per a la Recerca Biomédica
Colorectal Cancer
Mailed FIT-Based Outreach Interventions
Colorectal cancer (CRC) is the second most common cancer and the second leading cause of cancer-related mortality in Singapore. Although annual fecal immunochemical testing (FIT) and periodic colonoscopy are recommended for…
- Trial name
- NCT07852793
- Testing
- SMS Reminders, SMS reminders + mailed reminder, SMS reminders + mailed reminder + patient navigation
- Where
- 5 sites in Singapore
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- National Cancer Centre, Singapore
Colorectal Neoplasia, Screening Colonoscopy
Total Underwater Colonoscopy (TUC) for Improved Colorectal Cancer Screening: A Randomized Controlled Trial
Colorectal cancer (CRC), the third most diagnosed cancer and second most common cause of cancer death. CRCs develop from precursors like adenomas (about 70% of CRCs) or serrated lesions (SSLs) (about 25-30% of CRCs).
- Conditions
- Colorectal Neoplasia, Screening Colonoscopy, Colorectal Cancer, Colorectal Cancer Screening
- Trial name
- NCT06333392
- Testing
- Total underwater colonoscopy, Conventional colonoscopy
- Where
- 5 sites in Norway, Sweden
- Volunteers
- 1,070 people
- Sponsor
- Vestre Viken Hospital Trust
Colorectal Cancer Screening, Colonic Polyps/Colonoscopy/Colorectal Neoplasms
The Impact of Image-Assisted Colonoscope on Patient Experience, Physician Workload, and Examination Quality
Colonoscopy is the cornerstone for colorectal cancer screening, diagnosis, and post-treatment surveillance. Procedural quality is influenced by patient anatomy, particularly variations in colonic configuration such as sigmoid…
- Conditions
- Colorectal Cancer Screening, Colonic Polyps/Colonoscopy/Colorectal Neoplasms, Difficult Colonoscopy, Colonoscopy-Related Discomfort
- Trial name
- LOOP-p1 (NCT07541924)
- Testing
- CT-Based Image-Assisted Colonoscope Insertion
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- DONG WU
Colonoscopy (Procedure)
Use of GI Genius™ XR Software in Virtual Reality Headset During Routine Colonoscopy
This pilot study will evaluate the usability and safety of software GI Genius™ XR in the Apple Vision Pro™ virtual reality headset when used in conjunction with the GI Genius™ system during routine screening and surveillance…
- Trial name
- NCT07220174
- Testing
- software GI Genius™ XR on headset
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Cosmo Artificial Intelligence-AI Ltd
HELICOBACTER PYLORI INFECTIONS, Intestinal Metaplasia
Endoscopic Screening of Asymptomatic Patients for Helicobacter Pylori, Intestinal Metaplasia, and Barrett's Mucosa During Screening Colonoscopy
The goal of this observational study is to learn how common Helicobacter pylori (H. pylori) infection is in adults without stomach or upper gastrointestinal symptoms who are having a preventive screening colonoscopy.
- Conditions
- HELICOBACTER PYLORI INFECTIONS, Intestinal Metaplasia, Barett's Esophagus
- Trial name
- G-SCOGE (NCT07346521)
- Where
- Austria
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Sigmund Freud PrivatUniversitat
Adenoma Colon
White Light vs Narrow Band Imagingin the Diagnosis of Right Sided Colonic Polyps in Asymptomatic Subjects Undergoing Screening Colonoscopy
A randomized controlled crossover study to determine if narrow band imaging or white light endoscopy is superior in detecting right colonic polyps in average risk subjects undergoing screening colonoscopy
- Trial name
- WLEvsB-NBI (NCT05935124)
- Testing
- WLE first, then B-NBI
- Where
- Australia
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Western Sydney Local Health District
Colonoscopy, Colorectal Neoplasms
Efficacy of CAD in Screening Colonoscopy to Reduce the Risk of Advanced Adenoma at 3 Years.
The occurrence of interval cancers after colonoscopy raises the possibility of missed lesions. High- performance computer aided diagnosis (CAD) systems have been specially designed for the detection of colorectal lesions (CAD for…
- Conditions
- Colonoscopy, Colorectal Neoplasms, Intestinal Polyps
- Trial name
- IA-COLO 2 (NCT07299071)
- Testing
- Standard colonoscopy, Colonoscopy CADe
- Where
- 15 sites in France
- Volunteers
- 592 people
- Sponsor
- University Hospital, Bordeaux
Colorectal Neoplasms
AI-Based Stool Image Analysis for Colorectal Neoplasia Risk Assessment
This prospective observational substudy evaluates the association between artificial intelligence-derived features from stool images analyzed using the FAEX Health digital platform and fecal immunochemical test results in adults…
- Trial name
- FECAL-AI (NCT07740122)
- Testing
- AI-Based Stool Image Analysis
- Where
- Chile
- Volunteers
- 250 people
- Sponsor
- Servicio de Salud Metropolitano Sur Oriente
Polyps Colorectal, Colonoscopy
Optical Diagnosis of Neoplasia Using Artificial Intelligence
Computer-aided diagnosis (CADx) for colonoscopy aims to enhance optical diagnosis but often underperforms when used alongside humans due to under-reliance on AI.
- Conditions
- Polyps Colorectal, Colonoscopy, Optical Biopsy, Colorectal Cancer Control and Prevention
- Trial name
- FAIR (NCT07158203)
- Testing
- CADx simultaneously, CADx delayed
- Where
- 2 sites in Norway, Spain
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Fundacin Biomedica Galicia Sur
Colorectal Cancer, Advanced Adenoma
China Colorectal Cancer Screening Trial 1 (C-Cost1)
Colorectal cancer (CRC) is one of the most common malignancies in China. Currently, its incidence rate is increasing at a rate of 4% per year, exceeding the global annual average growth rate.
- Trial name
- NCT07090291
- Testing
- Colonoscopy, FIT, Blood test
- Where
- 7 sites in China
- Volunteers
- 60,300 people
- Sponsor
- Zhejiang University
Colonoscopy, Colorectal Cancer Screening
Triton 1.5 Robotic System for Diagnostic Colonoscopy in the Middle East
The purpose of this study is to gain early experience in the Triton 1.5 System in performing diagnostic, screening, surveillance, and basic therapeutic tasks (e.g., polypectomy for lesions ≤ 2 cm).
- Trial name
- CARE-UAE (NCT07835542)
- Testing
- Diagnostic Test: Diagnostic Colonoscopy
- Where
- United Arab Emirates
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Neptune Medical
Colorectal Cancer Screening, Bowel Cleansing for Colonoscopy
Cleansing Options in Out-Patient Setting to Improve Tolerance (COOP SIT) Trial
The purpose of this research is to compare patient preferences for two bowel preparation options: low-volume tablets (Suflave/Sutab) versus the standard colon preparation using Golytely (polyethylene glycol).
- Trial name
- COOP SIT (NCT07215000)
- Testing
- Golytely, Sulfave, Sutab
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Morehouse School of Medicine
CRC Screening, CRC (Colorectal Cancer)
Improving Rates of Diagnostic Colonoscopy in Native Americans
Colorectal cancer (CRC) is the second-leading cause of cancer death in both men and women in the United States. Compared to national averages, Native Americans (NA) endure a disproportionate burden of CRC incidence and…
- Trial name
- YVONNE-DX (NCT07115875)
- Testing
- Digital Outreach, In Person consultation
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- University of Oklahoma
Colonoscopy, Screening Colonscopy
What Influence Re-participation in the Danish Colorectal Screening Program.
This prospective observational study investigates how participants experience screening colonoscopy within the Danish colorectal cancer screening program and how these experiences relate to clinical findings, procedural factors…
- Conditions
- Colonoscopy, Screening Colonscopy, Pain
- Trial name
- NCT07353632
- Where
- 8 sites in Denmark
- Volunteers
- 8,000 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark