Clinical trials: Screening Colonoscopy
Adenoma Detection Rate
A Prospective Randomized Comparison of the Adenoma Detection Rate With a Disposable Cap (ENDOCUFF VISION®)
The aim of this study is to evaluate the effect of ENDOCUFF VISION® (caps with soft, about 1 cm long lateral feet of rubber ("Endocuff") to flatten the colon folds) on ADR in a real-life setting (general practices) and in a…
- Trial name
- Endocuff (NCT03442738)
- Testing
- Endocuff group
- Where
- 9 sites in Germany
- Volunteers
- 1,382 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Colonoscopy, Colonic Polyps
Implementation of Optical Diagnosis for Diminutive Polyps Amongst Endoscopists: Training and Long-term Quality Assurance
In this study, Dutch gastroenterologists who are certified for performing colonoscopies on FIT-positive patients in the Dutch population screening program are trained in optical diagnosis with validated methods.
- Trial name
- DISCOUNT2 (NCT02407925)
- Testing
- Feedback
- Where
- 13 sites in Netherlands
- Volunteers
- 3,144 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Colon Cancer
Cruciferous Vegetable Intake and Histone Status in Screening Colonoscopy Patients
This research study will assess cruciferous vegetable intake in patients presenting for screening colonoscopy and correlate intake with histone status and histone deacetylace (HDAC) expression in tissue biopsy specimens and…
- Trial name
- NCT01344330
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Colonic Polyp, Colon Cancer
Improving Outpatient Colonoscopy Bowel Prep With the Orton Score
Colonoscopy is a common endoscopic procedure which the UVA Gastroenterology \& Hepatology department performs on a daily basis for both screening/surveillance and diagnostic/therapeutic intent.
- Trial name
- NCT04093557
- Testing
- Orton Score, Typical Standard of Care
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Virginia
Colonoscopy, Colorectal Cancer Screening
Triton 1.5 Robotic System for Diagnostic Colonoscopy in the Middle East
The purpose of this study is to gain early experience in the Triton 1.5 System in performing diagnostic, screening, surveillance, and basic therapeutic tasks (e.g., polypectomy for lesions ≤ 2 cm).
- Trial name
- CARE-UAE (NCT07835542)
- Testing
- Diagnostic Test: Diagnostic Colonoscopy
- Where
- United Arab Emirates
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Neptune Medical
Outpatient Colonoscopy for Colorectal Cancer Screening or for Symptoms Suggestive of Colonic Diseases
Effect of Anesthesia on Force Application During Colonoscopy
The aim of the study is to determine if more force is used during colonoscopy when patients receive monitored anesthesia with propofol versus conscious sedation.
- Trial name
- CFM (NCT02101099)
- Testing
- Colonoscopy Force Monitor
- Where
- 3 sites in United States
- Volunteers
- 102 people
- Sponsor
- Artann Laboratories
Colorectal Cancer Screening, Bowel Cleansing for Colonoscopy
Cleansing Options in Out-Patient Setting to Improve Tolerance (COOP SIT) Trial
The purpose of this research is to compare patient preferences for two bowel preparation options: low-volume tablets (Suflave/Sutab) versus the standard colon preparation using Golytely (polyethylene glycol).
- Trial name
- COOP SIT (NCT07215000)
- Testing
- Golytely, Sulfave, Sutab
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Morehouse School of Medicine
CRC Screening, CRC (Colorectal Cancer)
Improving Rates of Diagnostic Colonoscopy in Native Americans
Colorectal cancer (CRC) is the second-leading cause of cancer death in both men and women in the United States. Compared to national averages, Native Americans (NA) endure a disproportionate burden of CRC incidence and…
- Trial name
- YVONNE-DX (NCT07115875)
- Testing
- Digital Outreach, In Person consultation
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- University of Oklahoma
Colon Polyp
Combined Chromoendoscopy and Water Method for Screening Colonoscopy
In a RCT in screening colonoscopy subjects, we will determine if chromoendoscopy using a dilute solution of Indigocarmine (IC) delivered by the water method (study method) will improve adenoma detection rate compared with the…
- Trial name
- NCT01383265
- Testing
- Water method and chromoendoscopy, Water method
- Where
- United States
- Volunteers
- 1,177 people
- Sponsor
- VA Northern California Health Care System
Cancer Colorectal
Evaluation of Letters Promoting Colorectal Cancer Testing
In this evaluation, 4 different versions of letters are being sent with mailers promoting colorectal cancer screening with an at-home test.
- Trial name
- NCT04548765
- Testing
- Letter, Loss Frame and Fear Appeals, Transparency
- Where
- United States
- Volunteers
- 14,644 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Colonic Polyps
Evaluation of Computer-assisted, Non-cathartic CT Colonography
The purpose of this study is to evaluate the performance of a non-cathartic, computer-assisted form of CT Colonography (Virtual Colonoscopy) for detection of pre-cancerous colon polyps in a group of asymptomatic screening…
- Trial name
- ncCTC (NCT01200303)
- Testing
- non-cathartic CTC
- Where
- 3 sites in United States
- Volunteers
- 605 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Colorectal Cancer
A New Method for Colorectal Cancer Screening: Colon Capsule Endoscopy Compared to Conventional Endoscopy
Introduction: Prevention of colorectal cancer (CRC) is feasible through polypectomy on screening colonoscopy. Patient acceptance remains the main limiting factor for execution.
- Trial name
- NCT00991003
- Testing
- Colon capsule endoscopy, Conventional Colonoscopy
- Where
- Switzerland
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Colorectal Cancer, Adenomatous Polyp of Colon
CRC Screening Using mSEPT9 (Methylated Septin 9) in Chinese Population
The purpose of this study is to evaluate the performance of the SEPT9 gene methylation assay in Colorectal cancer (CRC) high-risk population in Chinese hospitals using the opportunistic screening method.
- Conditions
- Colorectal Cancer, Adenomatous Polyp of Colon, Polyps, Other Disease/Injury
- Trial name
- RESEPT (NCT02540850)
- Where
- 4 sites in China
- Volunteers
- 1,031 people, healthy volunteers welcome
- Sponsor
- BioChain (Beijing) Science and Technology, Inc.
Colonoscopy, Screening Colonscopy
What Influence Re-participation in the Danish Colorectal Screening Program.
This prospective observational study investigates how participants experience screening colonoscopy within the Danish colorectal cancer screening program and how these experiences relate to clinical findings, procedural factors…
- Conditions
- Colonoscopy, Screening Colonscopy, Pain
- Trial name
- NCT07353632
- Where
- 8 sites in Denmark
- Volunteers
- 8,000 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Colorectal Neoplasms, Colonic Polyps
Accuracy of Detection Using ENdocuff Optimisation of Mucosal Abnormalities
The purpose of this study is to determine if a new device, called the Endocuff Vision (a small plastic device attached to the end of the colonoscope which helps by holding the folds of the bowel back to give a clear view of the…
- Conditions
- Colorectal Neoplasms, Colonic Polyps, Adenoma
- Trial name
- ADENOMA (NCT02552017)
- Testing
- Endocuff Vision
- Where
- 7 sites in United Kingdom
- Volunteers
- 1,772 people, healthy volunteers welcome
- Sponsor
- South Tyneside and Sunderland NHS Foundation Trust
Colorectal Neoplasms, Colonic Polyp
Effectiveness of Artificial Intelligence-Assisted Colonoscopy for Adenoma Detection in Routine Clinical Practice : a Prospective Multicenter Randomized Trial
This study is a multi-center, randomized controlled trial designed to evaluate whether an artificial intelligence (AI) system can assist endoscopists to improve the detection rate of colorectal adenomas and cancers during…
- Conditions
- Colorectal Neoplasms, Colonic Polyp, Adenoma, Colorectal Cancer
- Trial name
- AI-COLOADR (NCT07307547)
- Testing
- AI-Assisted Colonoscopy
- Where
- China
- Volunteers
- 3,300 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Screening Colonoscopy
Comparison of Adenoma Detection Rate Among Water, Carbon Dioxide and Air Methods of Minimal Sedation Colonoscopy
The purpose of this study is to determine which of the methods of colonoscopy viz. water insufflation or air insufflation or carbon dioxide insufflation is better in detecting the adenomas in colon and also which of these methods…
- Trial name
- NCT01782014
- Testing
- colonoscopy
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Diagnostic Colonoscopy Screening
Remifentanil Only vs. Midazolam and Meperidine During Elective Colonoscopy
The aim of the present study is to compare patient's recovery times after elective colonoscopy employing remifentanil only vs conventional combination of midazolam and meperidine
- Trial name
- remifentanil (NCT01693185)
- Testing
- Remifentanil, Midazolam, Meperidine
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Konkuk University Medical Center
Polypoid Lesions
Evaluation of Check-Cap C-Scan System in Providing Structural Information and Detection of Polypoid Lesions
The purpose of this study is to establish the efficacy of Check-Cap's C-Scan System in providing structural information on colonic polypoid lesions and masses, as an adjacent tool to FIT.
- Trial name
- NCT02990715
- Testing
- C-Scan System
- Where
- 3 sites in Israel
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Check-Cap Ltd.
Colorectal Cancer
Effect of Mailed Invites of Choice of Colonoscopy or FIT vs. Mailed FIT Alone on Colorectal Cancer Screening
This is a pragmatic, randomized, controlled trial comparing whether a mailed outreach intervention offering patients who are not up-to-date with colorectal cancer (CRC) a choice of completing a home Fecal Immunochemical Test…
- Trial name
- NCT03414125
- Testing
- FIT Screening Strategy, Choice Screening Strategy
- Where
- United States
- Volunteers
- 26,859 people
- Sponsor
- University of Texas Southwestern Medical Center