Clinical trials: Seasonal Allergies
Asthma
Montelukast in Pediatric Allergic Asthma (0476-336)(COMPLETED)
This is a 3-week study to evaluate FEV1 following treatment with drugs in persistent asthma which is also active during allergy seasons in pediatric patients with seasonal aeroallergen sensitivity.
- Trial name
- NCT00289874
- Testing
- montelukast sodium
- Volunteers
- 421 people
- Sponsor
- Organon and Co
Seasonal Allergic Rhinitis
To Study GSP 301 in Patients With Seasonal Allergic Rhinitis
Study to evaluate the two different strengths and dose regimen of GSP 301 to be effective in treatment of seasonal allergic rhinitis.
- Trial name
- NCT02318303
- Testing
- GSP 301-1 NS (QD), GSP 301-2 NS (BID), Olopatadine HCl-1 NS (QD)
- Where
- 10 sites in United States
- Volunteers
- 1,111 people
- Sponsor
- Glenmark Pharmaceuticals Ltd. India
Allergic Rhinitis
DYmista NAsal Spray in CHInese Patients
This study is a phase III clinical study to assess the efficacy and safety of Dymista® Nasal Spray in comparison to Azep® nasal spray and Flixonase® nasal spray in Chinese patients aged ≥ 12 years with moderate-to-severe allergic…
- Trial name
- DYNAS-CHI (NCT03599791)
- Testing
- Azelastine Hydrochl./Fluticasone Prop. 0.137/0.05 MG/ACTUAT, Azelastine Hydrochloride 0.137 MG/ACTUAT, Fluticasone Propionate 0.05 MG/ACTUAT
- Where
- 33 sites in China
- Volunteers
- 900 people
- Sponsor
- MEDA Pharma GmbH & Co. KG
Rhinitis, Allergic, Seasonal
Intralymphatic Immunotherapy in Increasing Doses, Substudy
The study evaluates the safety and effect of intralymphatic allergen specific immunotherapy in increasing doses. Patients with allergy to grass or birch will be treated with three intralymphatic injections in an up-dosing…
- Trial name
- NCT02975479
- Testing
- ALK Diluent, ALK Alutard SQ 5-grasses or ALK Alutard Birch
- Where
- 2 sites in Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Conjunctivitis, Allergic
A Methodology Development Clinical Trial of Reproxalap in Subjects With Seasonal Allergic Conjunctivitis Using the Environmental Exposure Chamber
An Exploratory Clinical Trial Evaluating Reproxalap Ophthalmic Solutions (0.25% and 0.5%) in Subjects with Seasonal Allergic Conjunctivitis Using the Environmental Exposure Chamber (EEC)
- Trial name
- NCT03709121
- Testing
- Reproxalap Ophthalmic Solution (0.25%), Reproxalap Ophthalmic Solution (0.5%), Vehicle Ophthalmic Solution
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Aldeyra Therapeutics, Inc.
Rhinitis, Allergic, Seasonal
Study of GW685698X In Patients With Seasonal Allergic Rhinitis
This study was designed to compare the efficacy and safety of an investigational nasal spray compared with placebo nasal spray and commonly used drug in the treatment of seasonal allergic rhinitis.
- Trial name
- NCT00363740
- Testing
- GW685698X Aqueous Nasal Spray
- Volunteers
- 38 people
- Sponsor
- GlaxoSmithKline
Type I Hypersensitivity
Assessment of the Contribution of Monophosphoryl Lipid A (MPL) to a Tree Pollen Allergy Vaccine
Allergen-specific immunotherapy (SIT), the administration of gradually increasing quantities of an allergen extract to an allergic patient, is a curative approach which directly treats the underlying allergic disease.
- Trial name
- NCT00118625
- Testing
- Tree MATA MPL
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Allergy Therapeutics
Allergy
A Trial of Grazax in Subjects With Hayfever
The trial is performed to evaluate the efficacy and safety of specific immunotherapy with Grazax for treatment of grass pollen induced allergy.
- Trial name
- NCT00421655
- Testing
- Grazax
- Where
- United States
- Volunteers
- 329 people
- Sponsor
- ALK-Abelló A/S
Seasonal Allergic Rhinitis
A Study to Evaluate the Efficacy and Safety of AK139 in Participants With Seasonal Allergic Rhinitis
This is a randomized, double-blind phase II clinical study to evaluate the efficacy and safety of AK139 in the treatment of participants with moderate to severe SAR
- Trial name
- NCT07436234
- Testing
- AK139
- Where
- China
- Volunteers
- 111 people
- Sponsor
- Akeso
Rhinitis, Allergic, Seasonal, Ragweed Pollen Allergy
Safety and Tolerability Study of Ragweed SLIT Tablets
The purpose of this study is to determine the safety and tolerability of several doses of ragweed pollen allergen extract administered as sublingual tablets in subjects with allergic rhinitis to ragweed.
- Trial name
- NCT01224834
- Testing
- Sublingual tablet of ragweed pollen allergen extract
- Where
- Hungary
- Volunteers
- 60 people
- Sponsor
- Stallergenes Greer
Birch Pollen Allergy
Study to Evaluate Safety, Tolerability and Explorative Efficacy of DM-101PX in Birch Pollen Allergic Participants
Randomized, double-blind placebo-controlled phase I trial with the primary aim to investigate safety and tolerability of three ascending dosing schemes of DM-101-PX in birch pollen allergic adults.
- Trial name
- NCT06037148
- Testing
- DM-101PX
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Desentum Oy
Birch Pollen Allergy, Healthy Control Subjects
Effect of the Nasal Provocation on the Breathing Style
The purpose of this study is to find out how the provocation of the nose changes breathing style (specifically, frequency and tidal volume changes)
- Trial name
- NCT02146300
- Testing
- 1. session birch pollen nasal exposure 2. session xylometazoline nasal exposure
- Where
- Finland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Oulu University Hospital
Allergy, Seasonal Allergic Rhinitis
Pilot Study of Allergy Immunotherapy and Prevention of Viral Respiratory Infections
The objective of this study is to determine whether there is a relationship between interferon-gamma levels and the incidence of viral respiratory infections in allergic children treated with allergy immunotherapy as compared to…
- Conditions
- Allergy, Seasonal Allergic Rhinitis, Perennial Allergic Rhinitis
- Trial name
- NCT00405899
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- West Penn Allegheny Health System
Allergic Rhinitis, Allergic Rhinoconjunctivitis
PURETHAL® Mites Dose Range Finding Study in Patients With Persistent Allergic Rhinitis/Rhinoconjunctivitis
The objective of the present study is to characterize the dose-response relationship of PURETHAL® Mites with a nasal provocation test in order to support the optimal dose in terms of clinical efficacy and safety.
- Trial name
- NCT01438463
- Testing
- PURETHAL Mites 6,667 AU/ml, PURETHAL Mites 20,000 AU/ml, PURETHAL Mites 50,000 AU/ml
- Where
- 35 sites in Austria, Belgium and 3 more
- Volunteers
- 290 people
- Sponsor
- HAL Allergy
Eosinophilic Esophagitis
Allergy Immunotherapy in the Management of Eosinophilic Esophagitis
Eosinophilic esophagitis (EoE) is a disease that has increased in incidence over the past decade that affects males predominantly, and in adults, is characterized by heartburn, dysphagia, strictures and food impactions.
- Trial name
- AIMEE (NCT01685034)
- Testing
- Allergy immunotherapy ("allergy shots")
- Sponsor
- United States Naval Medical Center, San Diego
Seasonal Allergic Rhinitis
Montelukast in Seasonal Allergic Rhinitis - Fall 1999 Study (0476A-117)
This study will evaluate the ability of oral montelukast/loratadine to improve the signs and symptoms of seasonal allergic rhinitis compared with loratadine alone, montelukast alone and placebo.
- Trial name
- NCT00963599
- Testing
- Comparator: montelukast/loratadine, Comparator: montelukast, Comparator: loratadine
- Volunteers
- 907 people
- Sponsor
- Organon and Co
Seasonal Allergic Rhinitis
Safety and Efficacy of Olopatadine HCl Nasal Spray in 6-11 Year Old Patients
A study to demonstrate the superiority of test article nasal spray relative to vehicle nasal spray for the treatment of seasonal allergic rhinitis for a 2 week period in patients aged 6 to 11 years with a history of seasonal…
- Trial name
- NCT00578929
- Testing
- Olopatadine Hydrochloride Nasal Spray 0.6%, Vehicle
- Where
- United States
- Volunteers
- 2,388 people
- Sponsor
- Alcon Research
Seasonal Allergic Rhinitis
A Safety and Efficacy Study of Ciclesonide Nasal Aerosol in Subjects 6-11 Years With Seasonal Allergic Rhinitis (SAR)
This is a 2-week, multicenter, randomized, double-blind, placebo-controlled, parallel group, efficacy and safety study of ciclesonide nasal aerosol administered once daily to male and premenarchal female subjects 6 to 11…
- Trial name
- NCT01458275
- Testing
- Ciclesonide nasal aerosol 37 mcg, ciclesonide nasal aerosol 74 mcg
- Where
- 66 sites in United States
- Volunteers
- 847 people
- Sponsor
- Sumitomo Pharma America, Inc.
Grass Pollen Allergy
Safety and Efficacy of Grass Pollen Allergoid in the Treatment of Allergic Rhinoconjunctivitis
The trial is performed to assess efficacy and safety of the Grass Pollen Allergoid in Allergic Rhinoconjunctivitis
- Trial name
- NCT00263601
- Testing
- Allergovit 6-grasses
- Where
- Germany
- Volunteers
- 154 people
- Sponsor
- Allergopharma GmbH & Co. KG
Allergic Rhinitis
Efficacy of Artemisia Pollen Specific Allergen Immunotherapy
Allergic rhinitis (AR) is a noninfectious inflammatory disease of the nasal mucosa mediated by immunoglobulin E (IgE) after exposure to allergens.
- Trial name
- NCT05318157
- Testing
- AIT drops, Clarityne, Rhinocort and Emedastine Difumarate Eye Drops
- Where
- 3 sites in China
- Volunteers
- 150 people
- Sponsor
- Beijing Tongren Hospital