Clinical trials: Seasonal Allergies
Birch Pollen Allergy, Healthy Control Subjects
Effect of the Nasal Provocation on the Breathing Style
The purpose of this study is to find out how the provocation of the nose changes breathing style (specifically, frequency and tidal volume changes)
- Trial name
- NCT02146300
- Testing
- 1. session birch pollen nasal exposure 2. session xylometazoline nasal exposure
- Where
- Finland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Oulu University Hospital
Conjunctivitis, Allergic
A Methodology Development Clinical Trial of Reproxalap in Subjects With Seasonal Allergic Conjunctivitis Using the Environmental Exposure Chamber
An Exploratory Clinical Trial Evaluating Reproxalap Ophthalmic Solutions (0.25% and 0.5%) in Subjects with Seasonal Allergic Conjunctivitis Using the Environmental Exposure Chamber (EEC)
- Trial name
- NCT03709121
- Testing
- Reproxalap Ophthalmic Solution (0.25%), Reproxalap Ophthalmic Solution (0.5%), Vehicle Ophthalmic Solution
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Aldeyra Therapeutics, Inc.
Seasonal Allergic Rhinitis
Study of ACT-129968 in Adult Patients With Seasonal Allergic Rhinitis
This study will assess the efficacy and safety of different doses of ACT-129968 in adult patients with seasonal allergic rhinitis, due to mountain cedar pollen.
- Trial name
- SAR (NCT01241214)
- Testing
- ACT-129968, Cetirizine
- Where
- 7 sites in United States
- Volunteers
- 579 people
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Seasonal Allergic Rhinitis
DNA Vaccine for Ragweed Allergic Adults
Various chemical modifications of allergens have been attempted to enhance efficacy, improve safety, and foster compliance with IT.
- Trial name
- NCT00346086
- Testing
- AIC (Amb a 1 Immunostimulatory Conjugate)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Johns Hopkins University
Seasonal Allergic Rhinitis
Efficacy and Safety Study of Desloratadine (MK-4117) in Japanese Participants With Seasonal Allergic Rhinitis (MK-4117-204)
This is an efficacy and safety study of desloratadine (MK-4117) in Japanese participants with seasonal allergic rhinitis (SAR). The primary hypothesis of this study is that the change from Baseline in Total Nasal Symptom Score…
- Trial name
- NCT02320396
- Testing
- Desloratadine 5 mg
- Volunteers
- 449 people
- Sponsor
- Organon and Co
Seasonal Allergic Rhinitis (SAR)
Efficacy and Safety of GSP 301 Nasal Spray in the Treatment of Seasonal Allergic Rhinitis (SAR)
Study to evaluate the efficacy, safety and tolerability of GSP 301 NS compared with placebo NS and individual monotherapy formulations for the treatment of Seasonal Allergic Rhinitis (subjects 12 years of age and older)
- Trial name
- GSP 301-304 (NCT02870205)
- Testing
- GSP 301 NS, GOM-NS, GMM-2 NS
- Where
- 43 sites in United States
- Volunteers
- 1,176 people
- Sponsor
- Glenmark Specialty S.A.
Rhinitis, Allergic, Seasonal
Dose-Ranging Study of Mometasone Furoate (MK-0887/SCH 032088) Nasal Spray in the Treatment of Children (Ages 6-11) With Seasonal Allergic Rhinitis (C95-161)
The purpose of this study was to identify the lowest dosage of mometasone furoate nasal spray (MFNS) that provided adequate efficacy with an acceptable safety profile for children (ages 6-11) with seasonal allergic rhinitis…
- Trial name
- NCT03879772
- Testing
- Mometasone furoate nasal spray, Beclomethasone dipropionate nasal spray, Chlorpheniramine maleate syrup
- Volunteers
- 679 people
- Sponsor
- Organon and Co
Seasonal Allergic Rhinitis
A Study to Evaluate the Safety & Effectiveness of a Nasal Spray to Treat Seasonal Allergies
The Purpose of this study is to determine if one allergy medication (0.15% azelastine hydrochloride) is more effective than Placebo alone
- Trial name
- NCT00719862
- Testing
- 0.15% azelastine hydrochloride Nasal Spray
- Where
- 34 sites in United States
- Volunteers
- 481 people
- Sponsor
- Meda Pharmaceuticals
Grass Pollen Allergy
Safety and Dose Finding Trial of BM32 in Subjects Suffering From Grass Pollen Allergy
The study will evaluate the dose response of immunotherapy against grass pollen allergy using the recombinant grass pollen vaccine BM32.
- Trial name
- NCT01445002
- Testing
- BM32
- Where
- Austria
- Volunteers
- 79 people
- Sponsor
- Biomay AG
Hay Fever
Observational Study With PASCALLERG ® in Patients With Hay Fever
The aim of this observational study is to document the therapeutic use of PASCALLERG ® for hay fever. Based on the survey is a decrease in disease-specific symptoms when taking PASCALLERG ® over a period of 4 weeks will be…
- Trial name
- NCT01660737
- Where
- Germany
- Volunteers
- 123 people
- Sponsor
- Pascoe Pharmazeutische Praeparate GmbH
Allergic Rhinitis, Allergy to Pollen
Evaluation of the Nasal and Conjunctival Response in Subjects Allergic to Birch Pollen in the ALYATEC Environmental Exposure Chamber
The aim of this study is to assess the nasal and conjunctival response in subjects allergic to birch pollen during controlled exposures in the ALYATEC environmental exposure chamber (EEC)
- Conditions
- Allergic Rhinitis, Allergy to Pollen, Rhinoconjunctivitis
- Trial name
- NCT04583202
- Testing
- Exposure to allergen
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Alyatec
Rhinitis, Allergic, Seasonal
A Dose-finding Study of ASP4070
The objective of this study was to evaluate the efficacy, safety, and dose-response of ASP4070 vaccinated in patients with cedar pollinosis.
- Trial name
- NCT03101267
- Testing
- ASP4070
- Where
- Japan
- Volunteers
- 150 people
- Sponsor
- Astellas Pharma Inc
Seasonal Allergic Rhinitis, Perennial Allergic Rhinitis
Preference for Clarinex Tablets vs. Zyrtec Tablets in Patients With Allergies (P03181)
This was a crossover study designed to see if patients with allergy symptoms preferred Clarinex® or Zyrtec®. Patients were randomized to take 7 days of Clarinex or Zyrtec treatment, followed by a 5 to 28-day washout period (days…
- Trial name
- NCT00794495
- Testing
- Desloratadine 5 mg (Clarinex), Cetirizine (Zyrtec)
- Volunteers
- 122 people
- Sponsor
- Organon and Co
Allergic Rhinitis, Chronic Urticaria
Safety Study of Levocetirizine Dihydrochloride Oral Liquid Formulation in Children Aged 1 to Less Than 6 Years Suffering From Allergic Rhinitis or Chronic Urticaria of Unknown Origin
The purpose of this study is to determine the safety of the oral formulation of levocetirizine in children ages 1 to less than 6 years old who suffer from allergic rhinitis or chronic urticaria of unknown origin.
- Trial name
- PAL (NCT00619801)
- Testing
- Levocetirizine
- Where
- 28 sites in United States
- Volunteers
- 173 people
- Sponsor
- UCB Pharma
Hayfever
Effects of Sublingual Immunotherapy on Grasspollen Allergy
The objective of the study is to document the objective immunological effects of SLIT on the nasal mucosa. Better understanding of these immunological pathways, in which this widely practised clinical therapy is likely to work…
- Trial name
- NCT00150514
- Testing
- Oralgen, Nasal biopsy, Nasal washing
- Where
- Netherlands
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Rhinitis, Allergic, Seasonal
Nasal Ocular Reflexes Contribute to Eye Symptoms
Eye symptoms of tearing, redness and itching frequently occur in patients with allergic rhinitis or hayfever. The purpose of this trial is to study whether placing an allergen (a substance that causes allergies) directly in your…
- Trial name
- NCT00117832
- Testing
- Azelastine nasal spray
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Severe Asthma, Allergy and Asthma
Multi-omics in Severe Asthma From Olive Pollen Allergy
Patients with severe olive pollen allergy exhibit characteristic sensitization profiles, marked by strong recognition of minor allergens like Ole e 7, and, more importantly, show poor clinical responses to pharmacological…
- Conditions
- Severe Asthma, Allergy and Asthma, Pollen; Allergy, Asthma
- Trial name
- DUPITEOLE (NCT07721376)
- Where
- Spain
- Volunteers
- 18 people
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Asthma, Respiratory Symptoms
Evaluation of the Control Level of Asthmatic Patients With Seasonal Increase of Respiratory Symptoms (High and/or Low)
To evaluate the level of control of Asthma (GINA : controlled, partially controlled, not controlled) of asthmatic patients consulting their general practitioner for a seasonal increase of respiratory symptoms (high and / or low)…
- Trial name
- SAISON (NCT00882128)
- Where
- 1,051 sites in France
- Volunteers
- 3,300 people
- Sponsor
- AstraZeneca
Seasonal Allergic Rhinitis
Safety and Efficacy of Bepotastine Besilate Nasal Spray in the Treatment of Seasonal Allergic Rhinitis
This is an efficacy study of bepotastine besilate nasal spray in seasonal allergic rhinitis.
- Trial name
- NCT01277341
- Testing
- Bepotastine Besilate Nasal Spray 2% Twice a day, Bepotastine Besilate Nasal Spray 3% Twice a day, Bepotastine Besilate Nasal Spray 4% Twice a day
- Where
- United States
- Volunteers
- 601 people
- Sponsor
- Bausch & Lomb Incorporated
Rhinitis, Allergic, Perennial and Seasonal
Regulatory AVAMYS Nasal Spray PMS
Non-interventional, open-label, single group, multicentric post-marketing surveillance to monitor the safety and effectiveness of AVAMYS nasal spray administered in Korean patients according to the prescribing information.
- Trial name
- NCT01001130
- Testing
- fluticasone furoate group
- Where
- South Korea
- Volunteers
- 3,244 people
- Sponsor
- GlaxoSmithKline