Clinical trials: Seasonal Allergies
Rhinitis, Allergic, Seasonal
Study of GW685698X In Patients With Seasonal Allergic Rhinitis
This study was designed to compare the efficacy and safety of an investigational nasal spray compared with placebo nasal spray and commonly used drug in the treatment of seasonal allergic rhinitis.
- Trial name
- NCT00363740
- Testing
- GW685698X Aqueous Nasal Spray
- Volunteers
- 38 people
- Sponsor
- GlaxoSmithKline
Allergic Rhinoconjunctivitis
Investigating Nasal and Ocular Immune Response to Conjunctival Allergen Exposure
The goal of this pilot study is to develop an eye allergen challenge model, called a conjunctival allergen challenge (CAC), using timothy grass as the allergen.
- Trial name
- INQUIRE (NCT07801625)
- Testing
- Standardized Allergen Extract, Timothy Grass (Phleum pratense)
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Dr. Anne Ellis
Asthma, Seasonal Allergic Rhinitis
Adolescent and Adult Subjects With Asthma and Seasonal Allergic Rhinitis Receiving Advair Diskus or Placebo
The four respiratory drugs being researched in this study have been approved by the US Food and Drug Administration (FDA) and are currently available by prescription at your drug store.
- Trial name
- NCT00385463
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Creighton University
Allergy
Phase 2 Study in Adults Sensitized to Cat
The purpose of this study is to identify an effective dose of allergen-specific immunotherapy for cat hair (Felis domesticus) administered by the oral/sublingual route.
- Trial name
- NCT00689299
- Testing
- Standardized Allergenic Extract, Cat Hair
- Where
- 3 sites in United States
- Volunteers
- 167 people
- Sponsor
- Antigen Laboratories, Inc.
Allergic Conjunctivitis, Dry Eye
PMCF Study to Evaluate Performance and Safety of "Xanoftal Next"
Dry eye disease (DED), also called keratoconjunctivitis sicca, is a multifactorial disease of the ocular surface characterized by loss of homeostasis of the tear film and accompanied by symptoms such as ocular discomfort and…
- Conditions
- Allergic Conjunctivitis, Dry Eye, Dry Eye Disease
- Trial name
- NCT05829499
- Testing
- HPMC-HA eyedrops
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- C.O.C. Farmaceutici S.r.l.
Rhinitis, Allergic, Seasonal, Ragweed Pollen Allergy
Safety and Tolerability Study of Ragweed SLIT Tablets
The purpose of this study is to determine the safety and tolerability of several doses of ragweed pollen allergen extract administered as sublingual tablets in subjects with allergic rhinitis to ragweed.
- Trial name
- NCT01224834
- Testing
- Sublingual tablet of ragweed pollen allergen extract
- Where
- Hungary
- Volunteers
- 60 people
- Sponsor
- Stallergenes Greer
Seasonal Allergic Rhinitis, Driving Ability
Rhinitis, Cognition and Driving Performance
This study investigates the effects of Allergic Rhinitis (AR) on driving ability and memory functions. Our group has previously shown that patients suffering from AR symptoms perform less well on tasks requiring sustained…
- Conditions
- Seasonal Allergic Rhinitis, Driving Ability, Cognition
- Trial name
- NCT01318681
- Testing
- cetirizine 10 mg, fluticasone furoate
- Where
- Netherlands
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Seasonal Allergic Rhinitis
Effect of a Probiotic on Seasonal Allergic Rhinitis Symptoms
The purpose of the current study is to evaluate the efficacy of administering a probiotic in adult human subjects suffering from allergic rhinitis during seasonal grass pollen exposure.
- Trial name
- NCT01653652
- Testing
- Probiotic, Maltodextrin
- Where
- Germany
- Volunteers
- 131 people
- Sponsor
- Société des Produits Nestlé (SPN)
Birch Pollen-Related Rhinoconjunctivitis, Rhinitis, Allergic, Seasonal
Safety, Tolerability and Pharmacodynamic Effects of Sublingual Immunotherapy (Tablets) With Recombinant Bet v1
To investigate the safety and tolerability of successive single rising doses of SLIT in subjects with allergic rhinitis and to investigate the safety and tolerability of multi high dose regimens of SLIT in subjects with allergic…
- Trial name
- NCT00396149
- Testing
- rBet v 1
- Where
- Denmark
- Volunteers
- 57 people
- Sponsor
- Stallergenes Greer
Hayfever
Effects of Sublingual Immunotherapy on Grasspollen Allergy
The objective of the study is to document the objective immunological effects of SLIT on the nasal mucosa. Better understanding of these immunological pathways, in which this widely practised clinical therapy is likely to work…
- Trial name
- NCT00150514
- Testing
- Oralgen, Nasal biopsy, Nasal washing
- Where
- Netherlands
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Seasonal Allergic Rhinitis
Vienna Challenge Chamber Study Using RV658 in Subjects With Allergic Rhinitis
RV568 is being developed for the treatment of diseases such as asthma, COPD and allergic rhinitis (e.g. hayfever). The main aim of this study is to investigate whether RV568 ameliorates the nasal symptoms to low doses of grass…
- Trial name
- NCT01230619
- Testing
- RV568
- Where
- Austria
- Volunteers
- 75 people
- Sponsor
- Respivert Ltd
Allergic Rhinitis, Rhinitis, Allergic, Seasonal
Investigate Two Trial Models; Vienna Challenge Chamber (in and Out of Season) and Park Study (in Season) Using a Drug for Seasonal Allergic Rhinitis
The aim of the study is to investigate the trial models, Vienna Challenge Chamber (VCC), in and out of season, and Park Study in season and the clinical efficacy of repeat doses of fluticasone propionate in subjects with seasonal…
- Trial name
- NCT00400998
- Testing
- Fluticasone Propionate
- Where
- Austria
- Volunteers
- 41 people
- Sponsor
- Research Consult GmbH
Allergic Rhinitis Due to Pollen
Nasal Allergen Challenge Test as a Method to Detect Clinical Reactivity Against Birch Pollen
Clinical efficacy and tolerability for allergen specific immunotherapy (AIT) with Itulazax (birch pollen extract tablet) is well established.
- Trial name
- NAC (NCT06085963)
- Testing
- ITULAZAX 12 SQ-Bet, Nacl
- Where
- Sweden
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Seasonal Allergic Rhinitis
To Study GSP 301 in Patients With Seasonal Allergic Rhinitis
Study to evaluate the two different strengths and dose regimen of GSP 301 to be effective in treatment of seasonal allergic rhinitis.
- Trial name
- NCT02318303
- Testing
- GSP 301-1 NS (QD), GSP 301-2 NS (BID), Olopatadine HCl-1 NS (QD)
- Where
- 10 sites in United States
- Volunteers
- 1,111 people
- Sponsor
- Glenmark Pharmaceuticals Ltd. India
Allergic Rhinitis
Study of Nasonex in the Relief of Nasal Congestion in Patients With Seasonal Allergic Rhinitis (Study P05529)
This study seeks to prospectively demonstrate that Nasonex is better than placebo in relieving nasal congestion in patients with seasonal allergic rhinitis.
- Trial name
- NCT00732381
- Testing
- Mometasone furoate nasal spray (MFNS)
- Volunteers
- 351 people
- Sponsor
- Organon and Co
Rhinitis, Allergic, Seasonal
Grass Pollen Immunotherapy Using a Cluster Regime for Seasonal Rhinitis and Asthma
The purpose of this study was to assess the effects of grass pollen immunotherapy on symptoms, bronchial hyperresponsiveness and quality of life in seasonal rhinitis and asthma.
- Trial name
- NCT00135642
- Testing
- Subcutaneous Alutard SQ grass pollen (Phleum pratense), Venepuncture: 20 ml blood sample taken on 2 separate visits
- Where
- United Kingdom
- Volunteers
- 44 people
- Sponsor
- Imperial College London
Rhinitis, Allergic, Seasonal, Asthma
Study of the Effectiveness and Safety of Desloratadine (Aerius) Syrup in Children With Hayfever With or Without Asthma (P03472)
The purpose of this study was to test the effectiveness and safety of desloratadine (Aerius) syrup in children with hayfever with or without asthma. Patients took desloratadine syrup once a day for 28 days.
- Trial name
- NCT00805324
- Testing
- Desloratadine
- Volunteers
- 54 people
- Sponsor
- Organon and Co
Rhinitis, Allergic, Seasonal
Intralymphatic Immunotherapy in Increasing Doses, Substudy
The study evaluates the safety and effect of intralymphatic allergen specific immunotherapy in increasing doses. Patients with allergy to grass or birch will be treated with three intralymphatic injections in an up-dosing…
- Trial name
- NCT02975479
- Testing
- ALK Diluent, ALK Alutard SQ 5-grasses or ALK Alutard Birch
- Where
- 2 sites in Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Allergic Rhinitis
Grazax Asthma Prevention
Investigation of the effect of Grazax (grass tablet) on asthma prevention in children with grass pollen allergy
- Trial name
- GAP (NCT01061203)
- Testing
- Grazax
- Where
- Finland
- Volunteers
- 812 people
- Sponsor
- ALK-Abelló A/S
Rhinitis, Allergic, Seasonal, Rhinitis, Allergic, Perennial
Study for the Treatment of Intermittent Allergic Rhinitis With Desloratadine (Study P04683)
This study will investigate the effectiveness of desloratadine in treating subjects with allergic rhinitis (AR) who meet the criteria for intermittent allergic rhinitis.
- Trial name
- NCT00406783
- Testing
- 5-mg Desloratadine
- Volunteers
- 547 people
- Sponsor
- Organon and Co